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Chemical Compound Review

Braunstein     dioxomanganese

Synonyms: Bruinsteen, pyrolusite, Mangandioxid, Mangaanbioxyde, Mangaandioxyde, ...
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Disease relevance of dioxomanganese


High impact information on dioxomanganese


Chemical compound and disease context of dioxomanganese


Biological context of dioxomanganese


Anatomical context of dioxomanganese


Associations of dioxomanganese with other chemical compounds


Gene context of dioxomanganese

  • Catalase (HPI), but not manganese-superoxide dismutase, was over-expressed under anaerobic conditions in a strain harboring a constitutive oxyR mutation [25].
  • We report the unexpected result that Escherichia coli isolates containing a multicopy plasmid (pDT1.5) carrying the manganese-superoxide dismutase gene sodA were more sensitive than the wild type to paraquat-mediated growth inhibition [26].
  • Paraquat-mediated selection for mutations in the manganese-superoxide dismutase gene sodA [26].
  • In order to test the hypothesis that the redox state of the cell is involved in regulating manganese-superoxide dismutase biosynthesis, we studied the effects of several oxidants on growth and superoxide dismutase biosynthesis [12].
  • It is concluded that the redox state of the cell possibly influences the biosynthesis and/or activity of an iron-containing repressor protein that serves to negatively regulate manganese-superoxide dismutase biosynthesis [12].

Analytical, diagnostic and therapeutic context of dioxomanganese


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  3. N2 fixation by Streptomyces thermoautotrophicus involves a molybdenum-dinitrogenase and a manganese-superoxide oxidoreductase that couple N2 reduction to the oxidation of superoxide produced from O2 by a molybdenum-CO dehydrogenase. Ribbe, M., Gadkari, D., Meyer, O. J. Biol. Chem. (1997) [Pubmed]
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  5. Down-regulation of Manganese-Superoxide Dismutase through Phosphorylation of FOXO3a by Akt in Explanted Vascular Smooth Muscle Cells from Old Rats. Li, M., Chiu, J.F., Mossman, B.T., Fukagawa, N.K. J. Biol. Chem. (2006) [Pubmed]
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  8. Insulin antiapoptotic signaling involves insulin activation of the nuclear factor kappaB-dependent survival genes encoding tumor necrosis factor receptor-associated factor 2 and manganese-superoxide dismutase. Bertrand, F., Desbois-Mouthon, C., Cadoret, A., Prunier, C., Robin, H., Capeau, J., Atfi, A., Cherqui, G. J. Biol. Chem. (1999) [Pubmed]
  9. Efficient gene transfer method into the whole heart through the coronary artery with hemagglutinating virus of Japan liposome. Sawa, Y., Kadoba, K., Suzuki, K., Bai, H.Z., Kaneda, Y., Shirakura, R., Matsuda, H. J. Thorac. Cardiovasc. Surg. (1997) [Pubmed]
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  11. Suppression of antioxidative enzyme expression by transforming growth factor-beta 1 in rat hepatocytes. Kayanoki, Y., Fujii, J., Suzuki, K., Kawata, S., Matsuzawa, Y., Taniguchi, N. J. Biol. Chem. (1994) [Pubmed]
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  13. Structure and gene expression of the E. coli Mn-superoxide dismutase gene. Takeda, Y., Avila, H. Nucleic Acids Res. (1986) [Pubmed]
  14. Cytokine-inducible enhancer with promoter activity in both the rat and human manganese-superoxide dismutase genes. Rogers, R.J., Chesrown, S.E., Kuo, S., Monnier, J.M., Nick, H.S. Biochem. J. (2000) [Pubmed]
  15. Localization of superoxide dismutases in Alzheimer's disease and Down's syndrome neocortex and hippocampus. Furuta, A., Price, D.L., Pardo, C.A., Troncoso, J.C., Xu, Z.S., Taniguchi, N., Martin, L.J. Am. J. Pathol. (1995) [Pubmed]
  16. Paraoxonase and superoxide dismutase gene polymorphisms and noise-induced hearing loss. Fortunato, G., Marciano, E., Zarrilli, F., Mazzaccara, C., Intrieri, M., Calcagno, G., Vitale, D.F., La Manna, P., Saulino, C., Marcelli, V., Sacchetti, L. Clin. Chem. (2004) [Pubmed]
  17. The distribution of copper, zinc- and manganese-superoxide dismutase, and glutathione peroxidase messenger ribonucleic acid in rat basal ganglia. Kunikowska, G., Jenner, P. Biochem. Pharmacol. (2002) [Pubmed]
  18. Renal mitochondrial dysfunction in spontaneously hypertensive rats is attenuated by losartan but not by amlodipine. de Cavanagh, E.M., Toblli, J.E., Ferder, L., Piotrkowski, B., Stella, I., Inserra, F. Am. J. Physiol. Regul. Integr. Comp. Physiol. (2006) [Pubmed]
  19. An immunocytochemical study of mitochondrial manganese-superoxide dismutase in the rat hippocampus after kainate administration. Kim, H.C., Jhoo, W.K., Kim, W.K., Suh, J.H., Shin, E.J., Kato, K., Ho Ko, K. Neurosci. Lett. (2000) [Pubmed]
  20. Protective role of copper, zinc superoxide dismutase against UVB-induced injury of the human keratinocyte cell line HaCaT. Sasaki, H., Akamatsu, H., Horio, T. J. Invest. Dermatol. (2000) [Pubmed]
  21. Inorganic materials and living organisms: surface modifications and fungal responses to various asbestos forms. Daghino, S., Martino, E., Fenoglio, I., Tomatis, M., Perotto, S., Fubini, B. Chemistry (Weinheim an der Bergstrasse, Germany) (2005) [Pubmed]
  22. Manganese(IV) Oxide Production by Acremonium sp. Strain KR21-2 and Extracellular Mn(II) Oxidase Activity. Miyata, N., Tani, Y., Maruo, K., Tsuno, H., Sakata, M., Iwahori, K. Appl. Environ. Microbiol. (2006) [Pubmed]
  23. Role of Kupffer cells in rat liver injury induced by diethyldithiocarbamate. Ishiyama, H., Ogino, K., Hobara, T. Eur. J. Pharmacol. (1995) [Pubmed]
  24. 6-Hydroxydopamine-lesioning of the nigrostriatal pathway in rats alters basal ganglia mRNA for copper, zinc- and manganese-superoxide dismutase, but not glutathione peroxidase. Kunikowska, G., Jenner, P. Brain Res. (2001) [Pubmed]
  25. Induction of the manganese-containing superoxide dismutase in Escherichia coli is independent of the oxidative stress (oxyR-controlled) regulon. Bowen, S.W., Hassan, H.M. J. Biol. Chem. (1988) [Pubmed]
  26. Paraquat-mediated selection for mutations in the manganese-superoxide dismutase gene sodA. Bloch, C.A., Ausubel, F.M. J. Bacteriol. (1986) [Pubmed]
  27. The absence of delayed graft function is predicted by the presence of manganese-superoxide dismutase in distal tubules of renal allografts. Boom, H., de Heer, E., van der Wal, A., Kruidenier, L., de Fijter, J.W., Benediktsson, H., Paul, L.C., van Es, L.A. Transplantation (2005) [Pubmed]
  28. Serum manganese-superoxide dismutase in patients with diabetes mellitus and thyroid dysfunction as judged by an ELISA. Ohno, H., Matsuura, N., Ishikawa, M., Sato, Y., Endo, Y., Taniguchi, N. Horm. Metab. Res. (1991) [Pubmed]
  29. Manganese induced brain lesions in Macaca fascicularis as revealed by positron emission tomography and magnetic resonance imaging. Eriksson, H., Tedroff, J., Thuomas, K.A., Aquilonius, S.M., Hartvig, P., Fasth, K.J., Bjurling, P., Långström, B., Hedström, K.G., Heilbronn, E. Arch. Toxicol. (1992) [Pubmed]
  30. Enzyme immunoassay for manganese-superoxide dismutase in serum and urine. Nishimura, N., Ito, Y., Adachi, T., Hirano, K., Sugiura, M., Sawaki, S. J. Pharmacobio-dyn. (1982) [Pubmed]
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