Chemical Compound Review:
AC1L18QD 7-[3-(3-hydroxyoct-1-enyl)- 4,7...
Synonyms:
- Thromboxane synthase inhibitors, thromboxane receptor antagonists and dual blockers in thrombotic disorders. Gresele, P., Deckmyn, H., Nenci, G.G., Vermylen, J. Trends Pharmacol. Sci. (1991)
- Effect of thromboxane and serotonin receptor antagonists on intracoronary platelet deposition in dogs with experimentally stenosed coronary arteries. Golino, P., Buja, L.M., Ashton, J.H., Kulkarni, P., Taylor, A., Willerson, J.T. Circulation (1988)
- Thromboxane is produced in response to intracoronary infusions of complement C5a in pigs. Cyclooxygenase blockade does not reduce the myocardial ischemia and leukocyte accumulation. Ito, B.R., Roth, D.M., Chenoweth, D.E., Lefer, A.M., Engler, R.L. Circ. Res. (1989)
- Internalization of the TXA2 receptor alpha and beta isoforms. Role of the differentially spliced cooh terminus in agonist-promoted receptor internalization. Parent, J.L., Labrecque, P., Orsini, M.J., Benovic, J.L. J. Biol. Chem. (1999)
- Arthur C. Corcoran Memorial Lecture. The role of eicosanoids in angiotensin-dependent hypertension. Nasjletti, A. Hypertension (1998)
- Increased glomerular thromboxane synthesis as a possible cause of proteinuria in experimental nephrosis. Remuzzi, G., Imberti, L., Rossini, M., Morelli, C., Carminati, C., Cattaneo, G.M., Bertani, T. J. Clin. Invest. (1985)
- Preliminary clinical studies with thromboxane synthase inhibitors and thromboxane receptor blockers. A review. Fiddler, G.I., Lumley, P. Circulation (1990)
- Thromboxane receptor blockade reduces renal injury in murine lupus nephritis. Spurney, R.F., Fan, P.Y., Ruiz, P., Sanfilippo, F., Pisetsky, D.S., Coffman, T.M. Kidney Int. (1992)
- Thromboxane contributes to pulmonary hypertension in ischemia-reperfusion lung injury. Zamora, C.A., Baron, D.A., Heffner, J.E. J. Appl. Physiol. (1993)
- Thromboxane-blocked swine as an experimental model of severe intravascular inflammation and septic shock. Jesmok, G., Gundel, R. Shock (1995)
- Ketoconazole inhibits alveolar macrophage production of inflammatory mediators involved in acute lung injury (adult respiratory distress syndrome). Williams, J.G., Maier, R.V. Surgery (1992)
- Involvement of brain thromboxane A in hypotension induced by haemorrhage in rats. Yalcin, M., Cavun, S., Yilmaz, M.S., Cengiz, F., Savci, V. Clin. Exp. Pharmacol. Physiol. (2005)
- Expression, purification, and spectroscopic characterization of human thromboxane synthase. Hsu, P.Y., Tsai, A.L., Kulmacz, R.J., Wang, L.H. J. Biol. Chem. (1999)
- Inhibition of thromboxane A synthesis in U937 cells by glucocorticoids. Lack of evidence for lipocortin 1 as the second messenger. Bienkowski, M.J., Petro, M.A., Robinson, L.J. J. Biol. Chem. (1989)
- Rapid, agonist-dependent phosphorylation in vivo of human thromboxane receptor isoforms. Minimal involvement of protein kinase C. Habib, A., Vezza, R., Créminon, C., Maclouf, J., FitzGerald, G.A. J. Biol. Chem. (1997)
- Role for transforming growth factor beta in thromboxane-induced increases in mesangial cell fibronectin synthesis. Negrete, H., Studer, R.K., Craven, P.A., DeRubertis, F.R. Diabetes (1995)
- 2-Arachidonoyl glycerol induces contraction of isolated rat aorta: role of cyclooxygenase-derived products. Stanke-Labesque, F., Mallaret, M., Lefebvre, B., Hardy, G., Caron, F., Bessard, G. Cardiovasc. Res. (2004)
- Effect of platelet-generated thromboxane on contractions of the pregnant rat uterus. Dubin, N.H., Blake, D.A., Egner, P.G., Ghodgaonkar, R.B. Biol. Reprod. (1982)
- Effect of amniotic fluid on platelet thromboxane production. Stuart, M., Wu, J., Sunderji, S., Ganley, C. J. Pediatr. (1987)
- Costimulation of Gi- and G12/G13-mediated signaling pathways induces integrin alpha IIbbeta 3 activation in platelets. Nieswandt, B., Schulte, V., Zywietz, A., Gratacap, M.P., Offermanns, S. J. Biol. Chem. (2002)
- A sequence within the cytoplasmic tail of GpIIb independently activates platelet aggregation and thromboxane synthesis. Stephens, G., O'Luanaigh, N., Reilly, D., Harriott, P., Walker, B., Fitzgerald, D., Moran, N. J. Biol. Chem. (1998)
- Effect of thromboxane synthase inhibition on eicosanoid levels and blood flow in ischemic rat brain. Pettigrew, L.C., Grotta, J.C., Rhoades, H.M., Wu, K.K. Stroke (1989)
- Role of thromboxane in producing portal hypertension following trauma-hemorrhage. Yokoyama, Y., Toth, B., Kitchens, W.C., Schwacha, M.G., Bland, K.I., Chaudry, I.H. Am. J. Physiol. Gastrointest. Liver Physiol. (2003)
- Mapping of the human thromboxane synthase gene (TBXAS1) to chromosome 7q34-q35 by two-color fluorescence in situ hybridization. Chase, M.B., Baek, S.J., Purtell, D.C., Schwartz, S., Shen, R.F. Genomics (1993)
- Pharmacological characterization of thromboxane and prostanoid receptors in human isolated urinary bladder. Palea, S., Toson, G., Pietra, C., Trist, D.G., Artibani, W., Romano, O., Corsi, M. Br. J. Pharmacol. (1998)
- Genomic structure and polymorphism of the human thromboxane synthase-encoding gene. Baek, S.J., Lee, K.D., Shen, R.F. Gene (1996)
- AT1 and TxA2/PGH2 receptors maintain hypertension throughout 2K,1C Goldblatt hypertension in the rat. Wilcox, C.S., Cardozo, J., Welch, W.J. Am. J. Physiol. (1996)
- In vitro thromboxane synthesis of depleted blood platelets following renal transplantation. Scharf, R.E. Thromb. Haemost. (1990)
- Annexin I concentration, phospholipase activity and thromboxane synthesis in irradiated rat lung. Ts'ao, C., Tsao, F.H., Taylor, J.M., Ward, W.F., Molteni, A. Radiat. Res. (1995)
- Anti-ischemic actions of a new thromboxane receptor antagonist during acute myocardial ischemia in cats. Brezinski, M.E., Yanagisawa, A., Darius, H., Lefer, A.M. Am. Heart J. (1985)
- Enhanced thromboxane synthesis during chronic reductions in uterine perfusion pressure in pregnant rats. Llinás, M.T., Alexander, B.T., Seedek, M., Abram, S.R., Crell, A., Granger, J.P. Am. J. Hypertens. (2002)