The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

Acetoxyacetamidofluorene     (ethanoyl-(9H-fluoren-2- yl)amino) ethanoate

Synonyms: NAAAF, NA-AAF, Acetoxy AAF, CCRIS 729, CHEMBL85327, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.





Chemical compound and disease context of ACETOXYACETYLAMINOFLUORENE






Associations of ACETOXYACETYLAMINOFLUORENE with other chemical compounds




Analytical, diagnostic and therapeutic context of ACETOXYACETYLAMINOFLUORENE


  1. Stimulation of recombination between homologous sequences on plasmid DNA and chromosomal DNA in Escherichia coli by N-acetoxy-2-acetylaminofluorene. Luisi-DeLuca, C., Porter, R.D., Taylor, W.D. Proc. Natl. Acad. Sci. U.S.A. (1984) [Pubmed]
  2. Differences in removal of acetylaminofluorene and pyrimidine dimers from the DNA of cultured mammalian cells. Amacher, D.E., Elliott, J.A., Lieberman, M.W. Proc. Natl. Acad. Sci. U.S.A. (1977) [Pubmed]
  3. Reconstitution of rods from tobacco mosaic virus protein and RNA modified with bulky carcinogens. Fraenkel-Conrat, H., Singer, B., Takanami, Y., Santella, R.M., Grunberger, D. Proc. Natl. Acad. Sci. U.S.A. (1982) [Pubmed]
  4. Recognition of chemical carcinogen-modified DNA by a DNA-binding protein. Moranelli, F., Lieberman, M.W. Proc. Natl. Acad. Sci. U.S.A. (1980) [Pubmed]
  5. Unscheduled DNA synthesis in mononuclear leukocytes from patients with colorectal polyps. Pero, R.W., Ritchie, M., Winawer, S.J., Markowitz, M.M., Miller, D.G. Cancer Res. (1985) [Pubmed]
  6. Cooperative structural transition of PM2 DNA at high ionic strength and its dependence on DNA damages. Kuhnlein, U., Tsang, S.S., Edwards, J. Nature (1980) [Pubmed]
  7. Effects of the hepatocarcinogen 2-acetylaminofluorene on insulin binding to microsomal and Golgi fractions of rat liver cells. Lev-Ran, A., Josefsberg, Z., Carr, B.I., Barseghian, G., Hwang, D. J. Natl. Cancer Inst. (1984) [Pubmed]
  8. Induction of DNA repair synthesis in human urothelial cells by the N-hydroxy metabolites of carcinogenic arylamines. Wang, C.Y., Christensen, B., Zukowski, K., Morton, K.C., Lee, M.S. J. Natl. Cancer Inst. (1984) [Pubmed]
  9. Reduced capacity for DNA repair synthesis in patients with or genetically predisposed to colorectal cancer. Pero, R.W., Miller, D.G., Lipkin, M., Markowitz, M., Gupta, S., Winawer, S.J., Enker, W., Good, R. J. Natl. Cancer Inst. (1983) [Pubmed]
  10. Lack of susceptibility of F344 rats to mammary tumor induction by topically applied fluorenylacetohydroxamic acids and their acetates. Malejka-Giganti, D., Rydell, R.E. J. Natl. Cancer Inst. (1978) [Pubmed]
  11. Role of depurination in mutagenesis by chemical carcinogens. Schaaper, R.M., Glickman, B.W., Loeb, L.A. Cancer Res. (1982) [Pubmed]
  12. DNA repair synthesis in fibroblast strains from patients with actinic keratosis, squamous cell carcinoma, basal cell carcinoma, or malignant melanoma after treatment with ultraviolet light, N-acetoxy-2-acetyl-aminofluorene, methyl methanesulfonate, and N-methyl-N-nitrosourea. Thielmann, H.W., Edler, L., Burkhardt, M.R., Jung, E.G. J. Cancer Res. Clin. Oncol. (1987) [Pubmed]
  13. Comparison of the frequency of diphtheria toxin and thioguanine resistance induced by a series of carcinogens to analyze their mutational specificities in diploid human fibroblasts. Aust, A.E., Drinkwater, N.R., Debien, K., Maher, V.M., McCormick, J.J. Mutat. Res. (1984) [Pubmed]
  14. Nonspecific inhibition of DNA repair by promoting and nonpromoting phorbol esters. Langenbach, R., Kuszynski, C. J. Natl. Cancer Inst. (1975) [Pubmed]
  15. Inhibition of dimethylnitrosamine-induced strand breaks in liver DNA and liver cell necrosis by diethyldithiocarbamate. Abanobi, S.E., Popp, J.A., Chang, S.K., Harrington, G.W., Lotlikar, P.D., Hadjiolov, D., Levitt, M., Rajalakshmi, S., Sarma, D.S. J. Natl. Cancer Inst. (1977) [Pubmed]
  16. Base substitution mutations induced by metabolically activated aflatoxin B1. Foster, P.L., Eisenstadt, E., Miller, J.H. Proc. Natl. Acad. Sci. U.S.A. (1983) [Pubmed]
  17. Another approach to in vivo estimation of genetic damage in humans. Pero, R.W., Mitelman, F. Proc. Natl. Acad. Sci. U.S.A. (1979) [Pubmed]
  18. High blood pressure related to carcinogen-induced unscheduled DNA synthesis, DNA carcinogen binding, and chromosomal aberrations in human lymphocytes. Pero, R.W., Bryngelsson, C., Mitelman, F., Thulin, T., Nordén, A. Proc. Natl. Acad. Sci. U.S.A. (1976) [Pubmed]
  19. Mutations activating human c-Ha-ras1 protooncogene (HRAS1) induced by chemical carcinogens and depurination. Vousden, K.H., Bos, J.L., Marshall, C.J., Phillips, D.H. Proc. Natl. Acad. Sci. U.S.A. (1986) [Pubmed]
  20. Involvement of mouse Rev3 in tolerance of endogenous and exogenous DNA damage. Van Sloun, P.P., Varlet, I., Sonneveld, E., Boei, J.J., Romeijn, R.J., Eeken, J.C., De Wind, N. Mol. Cell. Biol. (2002) [Pubmed]
  21. Inverse correlation of collagen production to anchorage independence and tumorigenicity in W8- and M-cell lines. Smith, B.D., Mahoney, A.P., Feldman, R.S. Cancer Res. (1983) [Pubmed]
  22. Quantification of aminofluorene adduct formation and repair in defined DNA sequences in mammalian cells using the UVRABC nuclease. Tang, M.S., Bohr, V.A., Zhang, X.S., Pierce, J., Hanawalt, P.C. J. Biol. Chem. (1989) [Pubmed]
  23. Mutagenesis of Chinese hamster cells in vitro by combination treatments with methyl methanesulfonate and N-acetoxy-2-acetylaminofluorene. Myhr, B.C., DiPaolo, J.A. Cancer Res. (1978) [Pubmed]
  24. Overlapping pathways for repair of damage from ultraviolet light and chemical carcinogens in human fibroblasts. Brown, A.J., Fickel, T.H., Cleaver, J.E., Lohman, P.H., Wade, M.H., Waters, R. Cancer Res. (1979) [Pubmed]
  25. Inhibitory effect of reducing agents on N-acetoxy- and N-hydroxy-2-acetylaminofluorene-induced mutagenesis. Rosin, M.P., Stich, H.F. Cancer Res. (1978) [Pubmed]
  26. Identification of DNA polymerases involved in DNA excision repair in diploid human fibroblasts. Dresler, S.L., Lieberman, M.W. J. Biol. Chem. (1983) [Pubmed]
  27. Differential inhibition of rat liver DNA polymerases in vitro by direct-acting carcinogens and the protective effect of a thiol reducing agent. Chan, J.Y., Becker, F.F. Biochem. J. (1981) [Pubmed]
  28. Recruitment of DNA damage checkpoint proteins to damage in transcribed and nontranscribed sequences. Jiang, G., Sancar, A. Mol. Cell. Biol. (2006) [Pubmed]
  29. N-acetoxy-N-acetyl-2-aminofluorene-induced mutagenesis in the lacI gene of Escherichia coli. Schaaper, R.M., Koffel-Schwartz, N., Fuchs, R.P. Carcinogenesis (1990) [Pubmed]
  30. Excision of N-acetoxy-2-acetylaminofluorene-induced DNA adducts from chromatin fractions of human fibroblasts. Kaneko, M., Cerutti, P.A. Cancer Res. (1980) [Pubmed]
  31. N-acetoxy-N-acetyl-2-aminofluorene-induced mutation spectrum in a human hprt cDNA shuttle vector integrated into mammalian cells. Ogawa, H.I., Kimura, H., Koya, M., Higuchi, H., Kato, T. Carcinogenesis (1994) [Pubmed]
  32. S-phase block and cell death in human lymphoblasts exposed to benzo[a]pyrene diol epoxide or N-acetoxy-2-acetylaminofluorene. Black, K.A., McFarland, R.D., Grisham, J.W., Smith, G.J. Toxicol. Appl. Pharmacol. (1989) [Pubmed]
  33. Clinical symptoms and DNA repair characteristics of xeroderma pigmentosum patients from Germany. Thielmann, H.W., Popanda, O., Edler, L., Jung, E.G. Cancer Res. (1991) [Pubmed]
  34. Detection of DNA adducts in N-acetoxy-2-acetylaminofluorene-treated human fibroblasts by means of immunofluorescence microscopy and quantitative immunoautoradiography. Muysken-Schoen, M.A., Baan, R.A., Lohman, P.H. Carcinogenesis (1985) [Pubmed]
  35. Antibodies to N-hydroxy-2-aminofluorene modified DNA as probes in the study of DNA reacted with derivatives of 2-acetylaminofluorene. Spodheim-Maurizot, M., Saint-Ruf, G., Leng, M. Carcinogenesis (1980) [Pubmed]
  36. Arsenic exposure is associated with decreased DNA repair in vitro and in individuals exposed to drinking water arsenic. Andrew, A.S., Burgess, J.L., Meza, M.M., Demidenko, E., Waugh, M.G., Hamilton, J.W., Karagas, M.R. Environ. Health Perspect. (2006) [Pubmed]
  37. Application of capillary liquid chromatography coupled with tandem mass spectrometric methods to the rapid screening of adducts formed by the reaction of N-acetoxy-N-acetyl-2-aminofluorene with calf thymus DNA. Wolf, S.M., Vouros, P. Chem. Res. Toxicol. (1994) [Pubmed]
WikiGenes - Universities