Chemical Compound Review:
CCRIS 3455 1,1-dimethylhydrazine; 1,2-dimethylhydrazine
Synonyms:
LS-194135, AC1L1W2A, Hydrazine, dimethyl-
- Effect of BCG on dimethylhydrazine induction of colon tumors in rats. Rogers, A.E., Gildin, J. J. Natl. Cancer Inst. (1975)
- Proliferating cell nuclear antigen expression in normal, preneoplastic, and neoplastic colonic epithelium of the rat. Yamada, K., Yoshitake, K., Sato, M., Ahnen, D.J. Gastroenterology (1992)
- Biochemical and clinical effects of selenium on dimethylhydrazine-induced colon cancer in rats. Jacobs, M.M., Forst, C.F., Beams, F.A. Cancer Res. (1981)
- Proliferative characteristics of chronic crypt cells in C57BL/6J and A/J mice as predictors of subsequent tumor formation. Glickman, L.T., Suissa, S., Fleiszer, D.M. Cancer Res. (1987)
- Cytotoxicity of 5,6-dihydroxytryptamine in dimethylhydrazine-induced carcinomas of rat colon. Tutton, P.J., Barkla, D.H. Cancer Res. (1977)
- Lactobacillus- and bifidobacterium-mediated antigenotoxicity in the colon of rats. Pool-Zobel, B.L., Neudecker, C., Domizlaff, I., Ji, S., Schillinger, U., Rumney, C., Moretti, M., Vilarini, I., Scassellati-Sforzolini, R., Rowland, I. Nutrition and cancer. (1996)
- Gene interaction and single gene effects in colon tumour susceptibility in mice. van Wezel, T., Stassen, A.P., Moen, C.J., Hart, A.A., van der Valk, M.A., Demant, P. Nat. Genet. (1996)
- Comparison of lesions induced in the Syrian golden hamster by diethylnitrosamine, dimethylhydrazine, and dibutylnitrosamine: influence of subsequent butylated hydroxyanisole treatment. Moore, M.A., Thamavit, W., Ito, N. J. Natl. Cancer Inst. (1987)
- Differential susceptibility of inbred mouse strains forecast by acute colonic proliferative response to methylazoxymethanol. Deschner, E.E., Long, F.C., Hakissian, M., Cupo, S.H. J. Natl. Cancer Inst. (1984)
- Effect of embryonic tissue immunization on chemically induced gastrointestinal tumors in rats. I. Can embryonic antigens act as rejection antigens? Bansal, B.R., Mark, R., Rhoads, J.E., Bansal, S.C. J. Natl. Cancer Inst. (1978)
- Inhibition of dimethylhydrazine-induced neoplasia of the large intestine by disulfiram. Wattenberg, L.W. J. Natl. Cancer Inst. (1975)
- Premalignant alterations in the glycosphingolipid composition of colonic epithelial cells of rats treated with 1,2-dimethylhydrazine. Dahiya, R., Dudeja, P.K., Brasitus, T.A. Cancer Res. (1987)
- The mode of growth and compartmentalization of neoplastic glands during experimental colon carcinogenesis. Chang, W.W. Am. J. Pathol. (1986)
- Dietary cholesterol deprivation improves survival and reduces incidence of metastatic colon cancer in dimethylhydrazine-pretreated rats. Cruse, J.P., Lewin, M.R., Clark, C.G. Gut (1982)
- Combination chemotherapy with 5-fluorouracil (5FU) and 1,3-bis(2-chloro-ethyl)-1-nitrosourea (BCNU) prolongs survival of rats with dimethylhydrazine-induced colon cancer. Danzi, M., Lewin, M.R., Cruse, J.P., Clark, C.G. Gut (1983)
- The effect of dietary folate on Apc and p53 mutations in the dimethylhydrazine rat model of colorectal cancer. Sohn, K.J., Puchyr, M., Salomon, R.N., Graeme-Cook, F., Fung, L., Choi, S.W., Mason, J.B., Medline, A., Kim, Y.I. Carcinogenesis (1999)
- Colostomy closure promotes cell proliferation and dimethylhydrazine-induced carcinogenesis in rat distal colon. Terpstra, O.T., Dahl, E.P., Williamson, R.C., Ross, J.S., Malt, R.A. Gastroenterology (1981)
- Amplification and elevated expression of c-myc in a chemically induced mouse colon tumor. Yander, G., Halsey, H., Kenna, M., Augenlicht, L.H. Cancer Res. (1985)
- The incidence of aberrant crypt foci and colonic carcinoma in dimethylhydrazine-treated rats varies in a site-specific manner and depends on tumor histology. Park, H.S., Goodlad, R.A., Wright, N.A. Cancer Res. (1997)
- Exon-specific DNA hypomethylation of the p53 gene of rat colon induced by dimethylhydrazine. Modulation by dietary folate. Kim, Y.I., Pogribny, I.P., Salomon, R.N., Choi, S.W., Smith, D.E., James, S.J., Mason, J.B. Am. J. Pathol. (1996)
- Elevated expression of an endogenous retroviral long terminal repeat in a mouse colon tumor. Augenlicht, L.H., Kobrin, D., Pavlovec, A., Royston, M.E. J. Biol. Chem. (1984)
- Serial observations of colonic carcinogenesis in the rat. Premalignant mucosa binds Ulex europeus agglutinin. Shioda, Y., Brown, W.R., Ahnen, D.J. Gastroenterology (1987)
- In vivo activation of mitogen-activated protein kinases in rat intestinal neoplasia. Licato, L.L., Keku, T.O., Wurzelmann, J.I., Murray, S.C., Woosley, J.T., Sandler, R.S., Brenner, D.A. Gastroenterology (1997)
- Comparison of the effects of an ornithine decarboxylase inhibitor on the intestinal epithelium and on intestinal tumors. Tutton, P.J., Barkla, D.H. Cancer Res. (1986)
- Effects of dietary fat on incidence of spontaneous and induced cancer in mice. Brown, R.R. Cancer Res. (1981)
- Tumor-associated antigens common to humans and chemically induced colonic tumors of the rat. Shetye, J.D., Rubio, C.A., Harmenberg, U., Ware, J., Duvander, A., Mellstedt, H.T. Cancer Res. (1990)
- Biochemical changes in premalignant intestines. Salser, J.S., Ball, W.J., Balis, M.E. Cancer Res. (1976)
- Target cells for the cytotoxic effects of carcinogens in the murine small bowel. Li, Y.Q., Fan, C.Y., O'Connor, P.J., Winton, D.J., Potten, C.S. Carcinogenesis (1992)
- Abnormalities of the cadherin-catenin complex in chemically-induced colo-rectal carcinogenesis. Tucker, E., Buda, A., Janghra, B., Cpoad, J., Moorghan, M., Havler, M., Dettmar, P., Pignatelli, M. The Proceedings of the Nutrition Society. (2003)
- Expression and chromosomal mapping of mouse Gpx2 gene encoding the gastrointestinal form of glutathione peroxidase, GPX-GI. Chu, F.F., Esworthy, R.S., Ho, Y.S., Bermeister, M., Swiderek, K., Elliott, R.W. Biomed. Environ. Sci. (1997)
- Transformed immortalized gastric epithelial cells by virulence factor CagA of Helicobacter pylori through Erk mitogen-activated protein kinase pathway. Zhu, Y., Zhong, X., Zheng, S., Du, Q., Xu, W. Oncogene (2005)
- Selective necrosis in dimethylhydrazine-induced rat colon tumors using phthalocyanine photodynamic therapy. Barr, H., Tralau, C.J., Boulos, P.B., MacRobert, A.J., Krasner, N., Phillips, D., Bown, S.G. Gastroenterology (1990)
- Monoclonal antibodies to a rat colon carcinoma: model for monoclonal antibody therapy of solid tumors. Douillard, J.Y., Laborda, J., Burg, C., Ridge, J., Levenbook, I., Blottière, H., Sela, B., Hoffman, T., Ben Ami, S. Cancer Res. (1989)
- Effects of epidermal growth factor and dimethylhydrazine on crypt size, cell proliferation, and crypt fission in the rat colon. Cell proliferation and crypt fission are controlled independently. Park, H.S., Goodlad, R.A., Ahnen, D.J., Winnett, A., Sasieni, P., Lee, C.Y., Wright, N.A. Am. J. Pathol. (1997)
- Induction of renal tumours in rats by the administration of 1,2 dimethylhydrazine. Sunter, J.P., Senior, P.V. J. Pathol. (1983)