Gene Review:
Faah - fatty acid amide hydrolase
Mus musculus
Synonyms:
AW412498, Anandamide amidohydrolase 1, Faah1, Fatty-acid amide hydrolase 1, Oleamide hydrolase 1
Lichtman,
Shelton,
Advani,
Cravatt,
Di Marzo,
Griffin,
De Petrocellis,
Brandi,
Bisogno,
Williams,
Grier,
Kulasegram,
Mahadevan,
Razdan,
Martin,
Cravatt,
Demarest,
Patricelli,
Bracey,
Giang,
Martin,
Lichtman,
Jacobsson,
Fowler,
Holt,
Rocksén,
Bucht,
Petersen,
Hansen,
Valenti,
Di Marzo,
Fowler,
Pacher,
Bátkai,
Osei-Hyiaman,
Offertáler,
Liu,
Harvey-White,
Brassai,
Járai,
Cravatt,
Kunos,
- The endogenous cannabinoid system protects against colonic inflammation. Massa, F., Marsicano, G., Hermann, H., Cannich, A., Monory, K., Cravatt, B.F., Ferri, G.L., Sibaev, A., Storr, M., Lutz, B. J. Clin. Invest. (2004)
- Mice lacking fatty acid amide hydrolase exhibit a cannabinoid receptor-mediated phenotypic hypoalgesia. Lichtman, A.H., Shelton, C.C., Advani, T., Cravatt, B.F. Pain (2004)
- Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase. Cravatt, B.F., Demarest, K., Patricelli, M.P., Bracey, M.H., Giang, D.K., Martin, B.R., Lichtman, A.H. Proc. Natl. Acad. Sci. U.S.A. (2001)
- Hemodynamic profile, responsiveness to anandamide, and baroreflex sensitivity of mice lacking fatty acid amide hydrolase. Pacher, P., Bátkai, S., Osei-Hyiaman, D., Offertáler, L., Liu, J., Harvey-White, J., Brassai, A., Járai, Z., Cravatt, B.F., Kunos, G. Am. J. Physiol. Heart Circ. Physiol. (2005)
- Arachidonoylserotonin and other novel inhibitors of fatty acid amide hydrolase. Bisogno, T., Melck, D., De Petrocellis, L., Bobrov MYu, n.u.l.l., Gretskaya, N.M., Bezuglov, V.V., Sitachitta, N., Gerwick, W.H., Di Marzo, V. Biochem. Biophys. Res. Commun. (1998)
- Fatty acid amide hydrolase (-/-) mice exhibit an increased sensitivity to the disruptive effects of anandamide or oleamide in a working memory water maze task. Varvel, S.A., Cravatt, B.F., Engram, A.E., Lichtman, A.H. J. Pharmacol. Exp. Ther. (2006)
- Characterization of the sleep-wake patterns in mice lacking fatty acid amide hydrolase. Huitron-Resendiz, S., Sanchez-Alavez, M., Wills, D.N., Cravatt, B.F., Henriksen, S.J. Sleep. (2004)
- Fatty acid amide hydrolase deficiency limits early pregnancy events. Wang, H., Xie, H., Guo, Y., Zhang, H., Takahashi, T., Kingsley, P.J., Marnett, L.J., Das, S.K., Cravatt, B.F., Dey, S.K. J. Clin. Invest. (2006)
- Fatty acid amide hydrolase controls mouse intestinal motility in vivo. Capasso, R., Matias, I., Lutz, B., Borrelli, F., Capasso, F., Marsicano, G., Mascolo, N., Petrosino, S., Monory, K., Valenti, M., Di Marzo, V., Izzo, A.A. Gastroenterology (2005)
- Pharmacological activity of fatty acid amides is regulated, but not mediated, by fatty acid amide hydrolase in vivo. Lichtman, A.H., Hawkins, E.G., Griffin, G., Cravatt, B.F. J. Pharmacol. Exp. Ther. (2002)
- Characterization of the 5'-sequence of the mouse fatty acid amide hydrolase. Puffenbarger, R.A., Kapulina, O., Howell, J.M., Deutsch, D.G. Neurosci. Lett. (2001)
- Conserved chromosomal location and genomic structure of human and mouse fatty-acid amide hydrolase genes and evaluation of clasper as a candidate neurological mutation. Wan, M., Cravatt, B.F., Ring, H.Z., Zhang, X., Francke, U. Genomics (1998)
- Comparative analysis of fatty acid amide hydrolase and cb(1) cannabinoid receptor expression in the mouse brain: evidence of a widespread role for fatty acid amide hydrolase in regulation of endocannabinoid signaling. Egertová, M., Cravatt, B.F., Elphick, M.R. Neuroscience (2003)
- Endocannabinoid system in frog and rodent testis: type-1 cannabinoid receptor and fatty acid amide hydrolase activity in male germ cells. Cobellis, G., Cacciola, G., Scarpa, D., Meccariello, R., Chianese, R., Franzoni, M.F., Mackie, K., Pierantoni, R., Fasano, S. Biol. Reprod. (2006)
- Increasing cannabinoid levels by pharmacological and genetic manipulation delay disease progression in SOD1 mice. Bilsland, L.G., Dick, J.R., Pryce, G., Petrosino, S., Di Marzo, V., Baker, D., Greensmith, L. FASEB J. (2006)
- Comparison of anandamide transport in FAAH wild-type and knockout neurons: evidence for contributions by both FAAH and the CB1 receptor to anandamide uptake. Ortega-Gutiérrez, S., Hawkins, E.G., Viso, A., López-Rodríguez, M.L., Cravatt, B.F. Biochemistry (2004)
- Characterization of palmitoylethanolamide transport in mouse Neuro-2a neuroblastoma and rat RBL-2H3 basophilic leukaemia cells: comparison with anandamide. Jacobsson, S.O., Fowler, C.J. Br. J. Pharmacol. (2001)
- A structure/activity relationship study on arvanil, an endocannabinoid and vanilloid hybrid. Di Marzo, V., Griffin, G., De Petrocellis, L., Brandi, I., Bisogno, T., Williams, W., Grier, M.C., Kulasegram, S., Mahadevan, A., Razdan, R.K., Martin, B.R. J. Pharmacol. Exp. Ther. (2002)
- Fatty-acid amide hydrolase is expressed in the mouse uterus and embryo during the periimplantation period. Paria, B.C., Zhao, X., Wang, J., Das, S.K., Dey, S.K. Biol. Reprod. (1999)
- Fatty acid amide hydrolase in brain ventricular epithelium: mutually exclusive patterns of expression in mouse and rat. Egertová, M., Michael, G.J., Cravatt, B.F., Elphick, M.R. J. Chem. Neuroanat. (2004)
- Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis. Gobbi, G., Bambico, F.R., Mangieri, R., Bortolato, M., Campolongo, P., Solinas, M., Cassano, T., Morgese, M.G., Debonnel, G., Duranti, A., Tontini, A., Tarzia, G., Mor, M., Trezza, V., Goldberg, S.R., Cuomo, V., Piomelli, D. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Lipopolysaccharide-induced pulmonary inflammation is not accompanied by a release of anandamide into the lavage fluid or a down-regulation of the activity of fatty acid amide hydrolase. Holt, S., Rocksén, D., Bucht, A., Petersen, G., Hansen, H.S., Valenti, M., Di Marzo, V., Fowler, C.J. Life Sci. (2004)