Gene Review:
Slc1a2 - solute carrier family 1 (glial high...
Mus musculus
Synonyms:
1700091C19Rik, 2900019G14Rik, AI159670, Eaat2, Excitatory amino acid transporter 2, ...
Ueda,
Watanabe,
Krady,
Kamichi,
Levison,
Iwama,
Takami,
Kawashima,
Jiang,
Takayasu,
Maeno,
Takatsuru,
Namura,
Takimoto,
Ozawa,
Hori,
Wada,
Nagata,
Nikkuni,
Stoffel,
Tanaka,
Nishikawa,
Körner,
Tanaka,
Okuyama,
Wada,
Cicchese,
Basu,
Lin,
Kikuchi,
Takahashi,
Yamada,
Druckman,
Wachtmann,
Manabe,
Iino,
Ichihara,
Watase,
Keller,
- Differential regulation of 5' splice variants of the glutamate transporter EAAT2 in an in vivo model of chemical hypoxia induced by 3-nitropropionic acid. Münch, C., Zhu, B.G., Leven, A., Stamm, S., Einkörn, H., Schwalenstöcker, B., Ludolph, A.C., Riepe, M.W., Meyer, T. J. Neurosci. Res. (2003)
- Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1. Tanaka, K., Watase, K., Manabe, T., Yamada, K., Watanabe, M., Takahashi, K., Iwama, H., Nishikawa, T., Ichihara, N., Kikuchi, T., Okuyama, S., Kawashima, N., Hori, S., Takimoto, M., Wada, K. Science (1997)
- Functions of the two glutamate transporters GLAST and GLT-1 in the retina. Harada, T., Harada, C., Watanabe, M., Inoue, Y., Sakagawa, T., Nakayama, N., Sasaki, S., Okuyama, S., Watase, K., Wada, K., Tanaka, K. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Alternative splicing of the 5'-sequences of the mouse EAAT2 glutamate transporter and expression in a transgenic model for amyotrophic lateral sclerosis. Münch, C., Ebstein, M., Seefried, U., Zhu, B., Stamm, S., Landwehrmeyer, G.B., Ludolph, A.C., Schwalenstöcker, B., Meyer, T. J. Neurochem. (2002)
- Neuronal soluble factors differentially regulate the expression of the GLT1 and GLAST glutamate transporters in cultured astroglia. Gegelashvili, G., Danbolt, N.C., Schousboe, A. J. Neurochem. (1997)
- Behavioral characterization of GLT1 (+/-) mice as a model of mild glutamatergic hyperfunction. Kiryk, A., Aida, T., Tanaka, K., Banerjee, P., Wilczynski, G.M., Meyza, K., Knapska, E., Filipkowski, R.K., Kaczmarek, L., Danysz, W. Neurotox. Res (2008)
- Glial glutamate transporters mediate a functional metabolic crosstalk between neurons and astrocytes in the mouse developing cortex. Voutsinos-Porche, B., Bonvento, G., Tanaka, K., Steiner, P., Welker, E., Chatton, J.Y., Magistretti, P.J., Pellerin, L. Neuron (2003)
- Unique anti-apoptotic activity of EAAC1 in injured motor neurons. Kiryu-Seo, S., Gamo, K., Tachibana, T., Tanaka, K., Kiyama, H. EMBO J. (2006)
- Glutamate transporter GLT-1 is transiently localized on growing axons of the mouse spinal cord before establishing astrocytic expression. Yamada, K., Watanabe, M., Shibata, T., Nagashima, M., Tanaka, K., Inoue, Y. J. Neurosci. (1998)
- Aquaporin-4 deficiency down-regulates glutamate uptake and GLT-1 expression in astrocytes. Zeng, X.N., Sun, X.L., Gao, L., Fan, Y., Ding, J.H., Hu, G. Mol. Cell. Neurosci. (2007)
- Glutamate transporter cluster formation in astrocytic processes regulates glutamate uptake activity. Zhou, J., Sutherland, M.L. J. Neurosci. (2004)
- Inhibition of glial glutamate transporter GLT-1 augments brain edema after transient focal cerebral ischemia in mice. Namura, S., Maeno, H., Takami, S., Jiang, X.F., Kamichi, S., Wada, K., Nagata, I. Neurosci. Lett. (2002)
- Molecular cloning of two glutamate transporter subtypes from mouse brain. Mukainaka, Y., Tanaka, K., Hagiwara, T., Wada, K. Biochim. Biophys. Acta (1995)
- Requirement of appropriate glutamate concentrations in the synaptic cleft for hippocampal LTP induction. Katagiri, H., Tanaka, K., Manabe, T. Eur. J. Neurosci. (2001)
- Roles of glial glutamate transporters in shaping EPSCs at the climbing fiber-Purkinje cell synapses. Takatsuru, Y., Takayasu, Y., Iino, M., Nikkuni, O., Ueda, Y., Tanaka, K., Ozawa, S. Neurosci. Res. (2006)
- Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer's disease brain contribute to neuronal death. Butterfield, D.A., Castegna, A., Lauderback, C.M., Drake, J. Neurobiol. Aging (2002)
- The 'glial' glutamate transporter, EAAT2 (Glt-1) accounts for high affinity glutamate uptake into adult rodent nerve endings. Suchak, S.K., Baloyianni, N.V., Perkinton, M.S., Williams, R.J., Meldrum, B.S., Rattray, M. J. Neurochem. (2003)
- Spinal cord GLT-1 glutamate transporter and blood glutamic acid alterations in motor neuron degeneration (Mnd) mice. Mennini, T., Bastone, A., Crespi, D., Comoletti, D., Manzoni, C. J. Neurol. Sci. (1998)
- Plasticity of astrocytic coverage and glutamate transporter expression in adult mouse cortex. Genoud, C., Quairiaux, C., Steiner, P., Hirling, H., Welker, E., Knott, G.W. PLoS Biol. (2006)
- Stimulation of excitatory amino acid release from adult mouse brain glia subcellular particles by high mobility group box 1 protein. Pedrazzi, M., Raiteri, L., Bonanno, G., Patrone, M., Ledda, S., Passalacqua, M., Milanese, M., Melloni, E., Raiteri, M., Pontremoli, S., Sparatore, B. J. Neurochem. (2006)
- Astrogliosis is delayed in type 1 interleukin-1 receptor-null mice following a penetrating brain injury. Lin, H.W., Basu, A., Druckman, C., Cicchese, M., Krady, J.K., Levison, S.W. Journal of neuroinflammation [electronic resource]. (2006)
- Glial glutamate transporters and maturation of the mouse somatosensory cortex. Voutsinos-Porche, B., Knott, G., Tanaka, K., Quairiaux, C., Welker, E., Bonvento, G. Cereb. Cortex (2003)
- Regulation of glutamate transporter GLAST and GLT-1 expression in astrocytes by estrogen. Pawlak, J., Brito, V., Küppers, E., Beyer, C. Brain Res. Mol. Brain Res. (2005)
- Functional analysis of glutamate transporters in excitatory synaptic transmission of GLAST1 and GLAST1/EAAC1 deficient mice. Stoffel, W., Körner, R., Wachtmann, D., Keller, B.U. Brain Res. Mol. Brain Res. (2004)
- The role of glial glutamate transporters in maintaining the independent operation of juvenile mouse cerebellar parallel fibre synapses. Marcaggi, P., Billups, D., Attwell, D. J. Physiol. (Lond.) (2003)
- Impaired glial glutamate transport in a mouse tuberous sclerosis epilepsy model. Wong, M., Ess, K.C., Uhlmann, E.J., Jansen, L.A., Li, W., Crino, P.B., Mennerick, S., Yamada, K.A., Gutmann, D.H. Ann. Neurol. (2003)
- Embryonic stem cell-derived astrocytes expressing drug-inducible transgenes: differentiation and transplantion into the mouse brain. Benveniste, R.J., Keller, G., Germano, I. J. Neurosurg. (2005)
- Decrease in glial glutamate transporter variants and excitatory amino acid receptor down-regulation in a murine model of ALS-PDC. Wilson, J.M., Khabazian, I., Pow, D.V., Craig, U.K., Shaw, C.A. Neuromolecular Med. (2003)
- Tissue specific variants of glutamate transporter GLT-1. Utsunomiya-Tate, N., Endou, H., Kanai, Y. FEBS Lett. (1997)