Gene Review:
ISL1 - ISL LIM homeobox 1
Homo sapiens
Synonyms:
ISLET1, Insulin gene enhancer protein ISL-1, Isl-1, Islet-1
- Characterization of the LIM/homeodomain gene islet-1 and single nucleotide screening in NIDDM. Riggs, A.C., Tanizawa, Y., Aoki, M., Wasson, J., Ferrer, J., Rabin, D.U., Vaxillaire, M., Froguel, P., Permutt, M.A. Diabetes (1995)
- Differences in neuronal differentiation between the transient cranial (Frorieps') and normal dorsal root ganglia. Avivi, C., Cui, S., Goren, S., Goldstein, R.S. Brain Res. Dev. Brain Res. (2002)
- First-degree relatives of patients with type I diabetes mellitus. Islet-cell antibodies and abnormal insulin secretion. Srikanta, S., Ganda, O.P., Rabizadeh, A., Soeldner, J.S., Eisenbarth, G.S. N. Engl. J. Med. (1985)
- Letter: Islet-cell hyperplasia and sudden infant death. Polak, J.M., Wigglesworth, J.S. Lancet (1976)
- A sib-pair analysis study of 15 candidate genes in French families with morbid obesity: indication for linkage with islet 1 locus on chromosome 5q. Clément, K., Dina, C., Basdevant, A., Chastang, N., Pelloux, V., Lahlou, N., Berlan, M., Langin, D., Guy-Grand, B., Froguel, P. Diabetes (1999)
- Requirement for LIM homeobox gene Isl1 in motor neuron generation reveals a motor neuron-dependent step in interneuron differentiation. Pfaff, S.L., Mendelsohn, M., Stewart, C.L., Edlund, T., Jessell, T.M. Cell (1996)
- Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells. Ahlgren, U., Pfaff, S.L., Jessell, T.M., Edlund, T., Edlund, H. Nature (1997)
- Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development. Takeuchi, J.K., Mileikovskaia, M., Koshiba-Takeuchi, K., Heidt, A.B., Mori, A.D., Arruda, E.P., Gertsenstein, M., Georges, R., Davidson, L., Mo, R., Hui, C.C., Henkelman, R.M., Nemer, M., Black, B.L., Nagy, A., Bruneau, B.G. Development (2005)
- Re: "Islet Hyperplasia in Adults: Challenge to Preoperatively Diagnose Non-insulinoma Pancreatogenic Hypoglycemia Syndrome". Pradeep, P.V., Mishra, A., Mishra, S.K. World journal of surgery (2007)
- Differential expression of Islet-1 in neural crest-derived ganglia: Islet-1 + dorsal root ganglion cells are post-mitotic and Islet-1 + sympathetic ganglion cells are still cycling. Avivi, C., Goldstein, R.S. Brain Res. Dev. Brain Res. (1999)
- An overview of the current status of islet cell transplantation as a treatment for diabetes mellitus. Islet cell transplantation, artificial pancreas, or genetic insulin synthesis offer possibilities for physiologic glucose regulation. Kakvan, M., Garber, A.J. Rhode Island medical journal. (1979)
- Interaction and association analysis of a type 1 diabetes susceptibility locus on chromosome 5q11-q13 and the 7q32 chromosomal region in Scandinavian families. Holm, P., Rydlander, B., Luthman, H., Kockum, I. Diabetes (2004)
- ISL1 physically interacts with BETA2 to promote insulin gene transcriptional synergy in non-beta cells. Peng, S.Y., Wang, W.P., Meng, J., Li, T., Zhang, H., Li, Y.M., Chen, P., Ma, K.T., Zhou, C.Y. Biochim. Biophys. Acta (2005)
- Hepatocyte Nuclear Factor 4 Alpha Ligand Binding and F Domains Mediate Interaction and Transcriptional Synergy with the Pancreatic Islet LIM HD Transcription Factor Isl1. Eeckhoute, J., Briche, I., Kurowska, M., Formstecher, P., Laine, B. J. Mol. Biol. (2006)
- A distal enhancer and an ultraconserved exon are derived from a novel retroposon. Bejerano, G., Lowe, C.B., Ahituv, N., King, B., Siepel, A., Salama, S.R., Rubin, E.M., Kent, W.J., Haussler, D. Nature (2006)
- Developmental regulation of the orphan receptor COUP-TF II gene in spinal motor neurons. Lutz, B., Kuratani, S., Cooney, A.J., Wawersik, S., Tsai, S.Y., Eichele, G., Tsai, M.J. Development (1994)
- The LIM/homeodomain protein islet-1 modulates estrogen receptor functions. Gay, F., Anglade, I., Gong, Z., Salbert, G. Mol. Endocrinol. (2000)
- Multipotential nestin and Isl-1 positive mesenchymal stem cells isolated from human pancreatic islets. Eberhardt, M., Salmon, P., von Mach, M.A., Hengstler, J.G., Brulport, M., Linscheid, P., Seboek, D., Oberholzer, J., Barbero, A., Martin, I., Müller, B., Trono, D., Zulewski, H. Biochem. Biophys. Res. Commun. (2006)
- Isl1 is upstream of sonic hedgehog in a pathway required for cardiac morphogenesis. Lin, L., Bu, L., Cai, C.L., Zhang, X., Evans, S. Dev. Biol. (2006)
- Islet Neogenesis Associated Protein (INGAP) modulates gene expression in cultured neonatal rat islets. Barbosa, H., Bordin, S., Stoppiglia, L., Silva, K., Borelli, M., Del Zotto, H., Gagliardino, J., Boschero, A. Regul. Pept. (2006)
- Enhanced isolated pancreatic islet recovery and functionality in rats by 17beta-estradiol treatment of brain death donors. Eckhoff, D.E., Eckstein, C., Smyth, C.A., Vilatoba, M., Bilbao, G., Rahemtulla, F.G., Young, C.J., Anthony Thompson, J., Chaudry, I.H., Contreras, J.L. Surgery (2004)
- Effect of exenatide on beta cell function after islet transplantation in type 1 diabetes. Ghofaili, K.A., Fung, M., Ao, Z., Meloche, M., Shapiro, R.J., Warnock, G.L., Elahi, D., Meneilly, G.S., Thompson, D.M. Transplantation (2007)
- Diabetes. Islet cell transplantation. Shapiro, A.M., Ryan, E.A., Lakey, J.R. Lancet (2001)
- Characterization of Donor Dendritic Cells and Enhancement of Dendritic Cell Efflux With cc-Chemokine Ligand 21: A Novel Strategy to Prolong Islet Allograft Survival. Fiorina, P., Jurewicz, M., Tanaka, K., Behazin, N., Augello, A., Vergani, A., Von Adrian, U., Smith, N.R., Sayegh, M.H., Abdi, R. Diabetes (2007)