Gene Review:
DPP4 - dipeptidyl-peptidase 4
Sus scrofa
Synonyms:
ADABP, CD26, DPPIV
- Involvement of both vectorial and transcytotic pathways in the preferential apical cell surface localization of rat dipeptidyl peptidase IV in transfected LLC-PK1 cells. Low, S.H., Wong, S.H., Tang, B.L., Hong, W.J. J. Biol. Chem. (1991)
- Cloning, purification, and enzymatic properties of dipeptidyl peptidase IV from the swine pathogen Streptococcus suis. Jobin, M.C., Martinez, G., Motard, J., Gottschalk, M., Grenier, D. J. Bacteriol. (2005)
- Chemical modification of dipeptidyl peptidase iv: involvement of an essential tryptophan residue at the substrate binding site. Harada, M., Hiraoka, B.Y., Fukasawa, K.M., Fukasawa, K. Arch. Biochem. Biophys. (1984)
- Mechanism of proline-specific proteinases: (I) Substrate specificity of dipeptidyl peptidase IV from pig kidney and proline-specific endopeptidase from Flavobacterium meningosepticum. Heins, J., Welker, P., Schönlein, C., Born, I., Hartrodt, B., Neubert, K., Tsuru, D., Barth, A. Biochim. Biophys. Acta (1988)
- Inhibition of dipeptidyl aminopeptidase IV (DP-IV) by Xaa-boroPro dipeptides and use of these inhibitors to examine the role of DP-IV in T-cell function. Flentke, G.R., Munoz, E., Huber, B.T., Plaut, A.G., Kettner, C.A., Bachovchin, W.W. Proc. Natl. Acad. Sci. U.S.A. (1991)
- Crystal structure of CD26/dipeptidyl-peptidase IV in complex with adenosine deaminase reveals a highly amphiphilic interface. Weihofen, W.A., Liu, J., Reutter, W., Saenger, W., Fan, H. J. Biol. Chem. (2004)
- Dipeptidyl peptidase IV inhibition potentiates the insulinotropic effect of glucagon-like peptide 1 in the anesthetized pig. Deacon, C.F., Hughes, T.E., Holst, J.J. Diabetes (1998)
- Neutral endopeptidase 24.11 and dipeptidyl peptidase IV are both mediators of the degradation of glucagon-like peptide 1 in the anaesthetised pig. Plamboeck, A., Holst, J.J., Carr, R.D., Deacon, C.F. Diabetologia (2005)
- The TATA-less, GC-rich porcine dipeptidylpeptidase IV (DPPIV) promoter shows bidirectional activity. Qvist, H., Sjöström, H., Norén, O. Biol. Chem. (1998)
- Rigidity and flexibility of dipeptidyl peptidase IV: crystal structures of and docking experiments with DPIV. Engel, M., Hoffmann, T., Manhart, S., Heiser, U., Chambre, S., Huber, R., Demuth, H.U., Bode, W. J. Mol. Biol. (2006)
- Loss of dipeptidylpeptidase IV activity in chronic rhinosinusitis contributes to the neurogenic inflammation induced by substance P in the nasal mucosa. Grouzmann, E., Monod, M., Landis, B., Wilk, S., Brakch, N., Nicoucar, K., Giger, R., Malis, D., Szalay-Quinodoz, I., Cavadas, C., Morel, D.R., Lacroix, J.S. FASEB J. (2002)
- Glucagon-like peptide-1-(7-36)amide is transformed to glucagon-like peptide-1-(9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the L cells of the porcine intestine. Hansen, L., Deacon, C.F., Orskov, C., Holst, J.J. Endocrinology (1999)
- Valine pyrrolidide preserves intact glucose-dependent insulinotropic peptide and improves abnormal glucose tolerance in minipigs with reduced beta-cell mass. Larsen, M.O., Rolin, B., Ribel, U., Wilken, M., Deacon, C.F., Svendsen, O., Gotfredsen, C.F., Carr, R.D. Exp. Diabesity Res. (2003)
- Proteins of the kidney microvillar membrane. Effects of monensin, vinblastine, swainsonine and glucosamine on the processing and assembly of endopeptidase-24.11 and dipeptidyl peptidase IV in pig kidney slices. Stewart, J.R., Kenny, A.J. Biochem. J. (1984)
- Is there a tripeptidyl peptidase in the renal brush-border membrane? Kenny, A.J., Ingram, J. Biochem. J. (1988)
- Early weaning stimulates intestinal brush border enzyme activities in piglets, mainly at the posttranscriptional level. Marion, J., Petersen, Y.M., Romé, V., Thomas, F., Sangild, P.T., Le Dividich, J., Le Huërou-Luron, I. J. Pediatr. Gastroenterol. Nutr. (2005)
- Biosynthesis of intestinal microvillar proteins. Pulse-chase labelling studies on maltase-glucoamylase, aminopeptidase A and dipeptidyl peptidase IV. Danielsen, E.M., Sjöström, H., Norén, O. Biochem. J. (1983)
- Isolation and characterization of two distinct low-density, Triton-insoluble, complexes from porcine lung membranes. Parkin, E.T., Turner, A.J., Hooper, N.M. Biochem. J. (1996)
- Membrane peptidases in the peripheral nervous system of the pig: their localization by immunohistochemistry at light and electron microscopic levels. Barnes, K., Bourne, A., Cook, P.A., Turner, A.J., Kenny, A.J. Neuroscience (1991)
- Proteins of the kidney microvillar membrane. Asymmetric labelling of the membrane by lactoperoxidase-catalysed radioiodination and by photolysis of 3,5-di[125I]iodo-4-azidobenzenesulphonate. Booth, A.G., Kenny, A.J. Biochem. J. (1980)
- In vivo modulation of CD26 (dipeptidyl peptidase IV) in the mouse: effects of polyreactive and monoreactive antibodies. Yamaguchi, N., Plant, C., Biancone, L., Bachovchin, W., McCluskey, R., Andres, G. Transplantation (1996)
- Localization of aminopeptidase N and dipeptidyl peptidase IV in pig striatum and in neuronal and glial cell cultures. Barnes, K., Kenny, A.J., Turner, A.J. Eur. J. Neurosci. (1994)
- Metabolism of glucagon-like peptide-2 in pigs: Role of dipeptidyl peptidase IV. Hansen, L., Hare, K.J., Hartmann, B., Deacon, C.F., Ugleholdt, R.K., Plamboeck, A., Holst, J.J. Regul. Pept. (2007)