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Gene Review

PODXL  -  podocalyxin-like

Homo sapiens

Synonyms: GCTM-2 antigen, Gp200, PC, PCLP, PCLP-1, ...
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Disease relevance of PODXL


High impact information on PODXL


Biological context of PODXL


Anatomical context of PODXL


Associations of PODXL with chemical compounds


Other interactions of PODXL


Analytical, diagnostic and therapeutic context of PODXL


  1. Podocalyxin variants and risk of prostate cancer and tumor aggressiveness. Casey, G., Neville, P.J., Liu, X., Plummer, S.J., Cicek, M.S., Krumroy, L.M., Curran, A.P., McGreevy, M.R., Catalona, W.J., Klein, E.A., Witte, J.S. Hum. Mol. Genet. (2006) [Pubmed]
  2. Human embryonal carcinoma tumor antigen, Gp200/GCTM-2, is podocalyxin. Schopperle, W.M., Kershaw, D.B., DeWolf, W.C. Biochem. Biophys. Res. Commun. (2003) [Pubmed]
  3. Podocalyxin-like protein 1 expression in primary hepatic tumours and tumour-like lesions. Heukamp, L.C., Fischer, H.P., Schirmacher, P., Chen, X., Breuhahn, K., Nicolay, C., Büttner, R., Gütgemann, I. Histopathology (2006) [Pubmed]
  4. Podocalyxin-like protein 1 expression is useful to differentiate pancreatic ductal adenocarcinomas from adenocarcinomas of the biliary and gastrointestinal tracts. Ney, J.T., Zhou, H., Sipos, B., Büttner, R., Chen, X., Klöppel, G., Gütgemann, I. Hum. Pathol. (2007) [Pubmed]
  5. The TRA-1-60 and TRA-1-81 human pluripotent stem cell markers are expressed on podocalyxin in embryonal carcinoma. Schopperle, W.M., DeWolf, W.C. Stem. Cells (2007) [Pubmed]
  6. Identification of podocalyxin-like protein as a high endothelial venule ligand for L-selectin: parallels to CD34. Sassetti, C., Tangemann, K., Singer, M.S., Kershaw, D.B., Rosen, S.D. J. Exp. Med. (1998) [Pubmed]
  7. The Wilms tumor suppressor-1 target gene podocalyxin is transcriptionally repressed by p53. Stanhope-Baker, P., Kessler, P.M., Li, W., Agarwal, M.L., Williams, B.R. J. Biol. Chem. (2004) [Pubmed]
  8. Molecular cloning and characterization of human podocalyxin-like protein. Orthologous relationship to rabbit PCLP1 and rat podocalyxin. Kershaw, D.B., Beck, S.G., Wharram, B.L., Wiggins, J.E., Goyal, M., Thomas, P.E., Wiggins, R.C. J. Biol. Chem. (1997) [Pubmed]
  9. Glomerular epithelial protein 1 and podocalyxin-like protein 1 in inflammatory glomerular disease (crescentic nephritis) in rabbit and man. Yang, D.H., Goyal, M., Sharif, K., Kershaw, D., Thomas, P., Dysko, R., Wiggins, R. Lab. Invest. (1996) [Pubmed]
  10. Podocalyxin in human haematopoietic cells. Kerosuo, L., Juvonen, E., Alitalo, R., Gylling, M., Kerjaschki, D., Miettinen, A. Br. J. Haematol. (2004) [Pubmed]
  11. Potential selectin L ligands involved in selective recruitment of peripheral blood CD16(-) natural killer cells into human endometrium. Yamaguchi, T., Kitaya, K., Daikoku, N., Yasuo, T., Fushiki, S., Honjo, H. Biol. Reprod. (2006) [Pubmed]
  12. Production and characterization of murine monoclonal antibodies against human podocalyxin. Rodr??guez, R.B., Butta, N., Larrucea, S., Alonso, S., Parrilla, R. Tissue Antigens (2006) [Pubmed]
  13. Role of transcription factor Sp1 and CpG methylation on the regulation of the human podocalyxin gene promoter. Butta, N., Larrucea, S., Alonso, S., Rodriguez, R.B., Arias-Salgado, E.G., Ayuso, M.S., González-Manchón, C., Parrilla, R. BMC Mol. Biol. (2006) [Pubmed]
  14. Cell cycle regulation and differentiation in the human podocyte lineage. Nagata, M., Nakayama, K., Terada, Y., Hoshi, S., Watanabe, T. Am. J. Pathol. (1998) [Pubmed]
  15. Novel endothelial cell markers in hepatocellular carcinoma. Chen, X., Higgins, J., Cheung, S.T., Li, R., Mason, V., Montgomery, K., Fan, S.T., van de Rijn, M., So, S. Mod. Pathol. (2004) [Pubmed]
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