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MeSH Review

Ophthalmic Artery

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Disease relevance of Ophthalmic Artery


High impact information on Ophthalmic Artery


Biological context of Ophthalmic Artery


Anatomical context of Ophthalmic Artery


Associations of Ophthalmic Artery with chemical compounds


Gene context of Ophthalmic Artery

  • Endothelium-derived nitric oxide (NO), which is catalysed by nitric oxide synthase (NOS), is a potent modulator of vascular tone in the human ophthalmic artery, which is normally in a state of constant vasodilation due to the actions of NO [25].
  • CONCLUSION: We concluded that COPD is associated with impaired retrobulbar hemodynamics, especially in the ophthalmic artery [26].
  • These findings demonstrate that in the human ophthalmic artery, endothelium-derived nitric oxide and endothelin are very potent modulators of vascular tone, suggesting that they play an important role in the regulation of local blood flow in the eye [21].
  • RESULTS: Adrenomedullin dose dependently increased choroidal blood flow and flow velocity in the ophthalmic artery [16].
  • METHODS: Rat ophthalmic arteries (diameter of 217 +/- 6 microm, n = 22) were isolated, cannulated with glass pipettes in an arteriograph and pressurized in a physiological buffer [27].

Analytical, diagnostic and therapeutic context of Ophthalmic Artery


  1. Intraarterial papaverine infusion for cerebral vasospasm after subarachnoid hemorrhage. Clouston, J.E., Numaguchi, Y., Zoarski, G.H., Aldrich, E.F., Simard, J.M., Zitnay, K.M. AJNR. American journal of neuroradiology. (1995) [Pubmed]
  2. Low concentrations of lithium and cyclooxygenase inhibitors enhance endothelin-1 (ET-1)-induced contractions in human temporal artery, but not in porcine ophthalmic artery. Bakken, I.J., Vincent, M.B., White, L.R., Cappelen, J., Skaanes, K.O., Sjaastad, O. Headache. (1992) [Pubmed]
  3. Endothelin-1 inhibits the vasodilation induced by substance P in isolated porcine ophthalmic artery. Vincent, M.B., Bakken, I.J., White, L.R. Funct. Neurol. (1992) [Pubmed]
  4. A case of Tolosa-Hunt syndrome affecting both the cavernous sinuses and the hypophysis, and associated with C3 and C4 aneurysms. Kambe, A., Tanaka, Y., Numata, H., Kawakami, S., Kurosaki, M., Ohtake, M., Kamitani, H., Miyata, H., Ohama, E., Watanabe, T. Surgical neurology. (2006) [Pubmed]
  5. The visual outcome in cases of neovascular glaucoma. Molteno, A.C., Haddad, P.J. Australian and New Zealand journal of ophthalmology. (1985) [Pubmed]
  6. Nitric oxide and ocular blood flow in patients with IDDM. Schmetterer, L., Findl, O., Fasching, P., Ferber, W., Strenn, K., Breiteneder, H., Adam, H., Eichler, H.G., Wolzt, M. Diabetes (1997) [Pubmed]
  7. Bilateral increase in CO2 reactivity after unilateral carotid endarterectomy. Visser, G.H., van Huffelen, A.C., Wieneke, G.H., Eikelboom, B.C. Stroke (1997) [Pubmed]
  8. Cerebral and ocular hemodynamic effects of sumatriptan in the nitroglycerin headache model. Schmetterer, L., Wolzt, M., Krejcy, K., Graselli, U., Findl, O., Eichler, H.G., Singer, E.A. Clin. Pharmacol. Ther. (1996) [Pubmed]
  9. Myogenic tone and reactivity of rat ophthalmic artery in acute exposure to high glucose and in a type II diabetic model. Ito, I., Jarajapu, Y.P., Guberski, D.L., Grant, M.B., Knot, H.J. Invest. Ophthalmol. Vis. Sci. (2006) [Pubmed]
  10. Sumatriptan relaxes isolated porcine ophthalmic artery, but inhibits VIP-induced relaxation. Vincent, M.B., White, L.R., Bakken, I.J., Sjaastad, O. Cephalalgia : an international journal of headache. (1993) [Pubmed]
  11. The mechanisms of the ocular autonomic dysfunction during the intracarotid amytal suppression test. DeToledo, J.C., Ramsay, R.E. Epilepsy Res. (1997) [Pubmed]
  12. The effect of systemic nitric oxide-synthase inhibition on ocular fundus pulsations in man. Schmetterer, L., Krejcy, K., Kastner, J., Wolzt, M., Gouya, G., Findl, O., Lexer, F., Breiteneder, H., Fercher, A.F., Eichler, H.G. Exp. Eye Res. (1997) [Pubmed]
  13. Vascular responsiveness to periarterial electrical nerve stimulation on canine ophthalmic arteries. Ohkubo, H., Chiba, S. Curr. Eye Res. (1988) [Pubmed]
  14. Regulation of ocular blood flow during increases of arterial blood pressure. Michelson, G., Groh, M., Gründler, A. The British journal of ophthalmology. (1994) [Pubmed]
  15. Differential effects of diltiazem and nitroglycerin on cytosolic Ca2+ concentration and on force in the bovine ophthalmic artery. Hiroishi, G., Kobayashi, S., Nishimura, J., Inomata, H., Kanaide, H. Invest. Ophthalmol. Vis. Sci. (1996) [Pubmed]
  16. Effects of adrenomedullin on ocular hemodynamic parameters in the choroid and the ophthalmic artery. Dorner, G.T., Garhöfer, G., Huemer, K.H., Golestani, E., Zawinka, C., Schmetterer, L., Wolzt, M. Invest. Ophthalmol. Vis. Sci. (2003) [Pubmed]
  17. Relationship between ocular pulse pressures and retinal vessel velocities. Michelson, G., Harazny, J. Ophthalmology (1997) [Pubmed]
  18. Sevoflurane effects on retrobulbar arteries blood flow in children. Geeraerts, T., Devys, J.M., Berges, O., Dureau, P., Plaud, B. British journal of anaesthesia. (2005) [Pubmed]
  19. Superselective injection of BCNU through a latex calibrated-leak balloon. Debrun, G.M., Davis, K.R., Hochberg, F.H. AJNR. American journal of neuroradiology. (1983) [Pubmed]
  20. Heterogeneity of endothelium-dependent regulation in ophthalmic and ciliary arteries. Haefliger, I.O., Flammer, J., Lüscher, T.F. Invest. Ophthalmol. Vis. Sci. (1993) [Pubmed]
  21. Nitric oxide and endothelin-1 are important regulators of human ophthalmic artery. Haefliger, I.O., Flammer, J., Lüscher, T.F. Invest. Ophthalmol. Vis. Sci. (1992) [Pubmed]
  22. Effect of topical timolol maleate on the ophthalmic artery blood pressure. Grunwald, J.E., Furubayashi, C. Invest. Ophthalmol. Vis. Sci. (1989) [Pubmed]
  23. Mechanisms of histamine-induced relaxation in external and internal ophthalmic arteries. Wang, Y., Okamura, T., Toda, N. Invest. Ophthalmol. Vis. Sci. (1993) [Pubmed]
  24. Functional role of nerve-derived nitric oxide in isolated dog ophthalmic arteries. Toda, N., Kitamura, Y., Okamura, T. Invest. Ophthalmol. Vis. Sci. (1995) [Pubmed]
  25. Association study of the 5' flanking regions of endothelial-nitric oxide synthase and endothelin-1 genes in familial primary open-angle glaucoma. Tunny, T.J., Richardson, K.A., Clark, C.V. Clin. Exp. Pharmacol. Physiol. (1998) [Pubmed]
  26. Color Doppler evaluation of the ocular arterial flow changes in chronic obstructive pulmonary disease. Ozer, T., Altin, R., Ugurbas, S.H., Ozer, Y., Mahmutyazicioglu, K., Kart, L. European journal of radiology. (2006) [Pubmed]
  27. Myogenic tone and reactivity of the rat ophthalmic artery. Jarajapu, Y.P., Grant, M.B., Knot, H.J. Invest. Ophthalmol. Vis. Sci. (2004) [Pubmed]
  28. Sequentially combined hormone replacement therapy reduces impedance to flow within the uterine and central retinal arteries in healthy postmenopausal women. van Baal, W.M., Kenemans, P., Stehouwer, C.D., Peters-Muller, E.R., van Vugt, J.M., van der Mooren, M.J. Am. J. Obstet. Gynecol. (1999) [Pubmed]
  29. Unexpected bleeding caused by arterial variation inferolateral to levator palpebrae. Kim, B.G., Youn, D., Yoon, E.S., Lee, Y.G., Jin, H., Hahm, J.W., Seo, J.D. Aesthetic plastic surgery. (2003) [Pubmed]
  30. Effect of prostaglandin E1 on ophthalmic artery velocimetry in a pre-eclamptic woman with visual disturbance caused by retinal arterial narrowing. Ohno, Y., Kawai, M., Arii, Y., Mizutani, S. Gynecol. Obstet. Invest. (2002) [Pubmed]
  31. The value of electroencephalography and ocular pneumoplethysmography in carotid shunting. Moll, F.L., Eikelboom, B.C., Ackerstaff, R. The Netherlands journal of surgery. (1982) [Pubmed]
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