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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Automatic Data Processing

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Disease relevance of Automatic Data Processing

  • These results are yet another demonstration in migraine of an interictal habituation deficit in cortical information processing, which might favour lactate accumulation in sensory cortices during sustained activation [1].
  • Sixteen patients with a definitive diagnosis of multiple sclerosis (MS) and an equal number of matched controls were administered tests of memory and information processing speed [2].
  • The increase in GABA(A) receptor function observed following injury could potentially contribute to dysfunctional synaptic function and information processing as well as unconsciousness and coma following human brain trauma [3].
  • The distribution of NOS found in this study suggests a novel role for nitric oxide in an early stage of mechanosensory information processing in all thoracic neuromeres and an additional role in the prothoracic ganglion, which might be related to behavioural specializations of the forelegs [4].
  • Each infant's summed total of daily PCS scores, a single AIM score, and birth weight were extracted from the hospital's decision-support data files and used as independent variables in regression analyses to determine correlations with lengths of hospital stay, ancillary resource utilizations, and hospital charges [5].

Psychiatry related information on Automatic Data Processing


High impact information on Automatic Data Processing


Chemical compound and disease context of Automatic Data Processing


Biological context of Automatic Data Processing

  • Our observations confirm a longstanding hypothesis about dorsal stream dysfunction in WS, demonstrate effects of a localized abnormality on visual information processing in humans, and define a systems-level phenotype for mapping genetic determinants of visuoconstructive function [21].
  • The manner in which information processing proceeds and the relationship of the components of the cerebral "event-related" evoked potential (ERP) to the presumed stages of such processing are uncertain [22].
  • Consistent with this, all ESTs derived from several genes (zein and adh1) that are known to be exclusively expressed in kernels or preferentially expressed under anaerobic conditions, respectively, were exclusively tagged with bar codes associated with mRNA pools prepared from kernel and anaerobically treated seedlings, respectively [23].
  • Commentary on: "Effects of scopolamine and nicotine on human rapid information processing performance." Psychopharmacology (1984) 82:147-150. Nicotine improves information processing: saying the unthinkable [24].
  • It is suggested that functions of 5'-nucleotidase in purinergic neuromodulation and cell adhesion are unique to the olfactory bulb, and implied in synaptic arrangements and information processing [25].

Anatomical context of Automatic Data Processing


Associations of Automatic Data Processing with chemical compounds

  • The heterotrimeric guanine nucleotide-binding proteins (G proteins) act as switches that regulate information processing circuits connecting cell surface receptors to a variety of effectors [31].
  • The amino acid glutamate is the major excitatory neurotransmitter in a range of organisms from Caenorhabditis elegans to mammals, and it mediates the information processing that underlies essentially all behavior [32].
  • These and other data support the hypothesis that the primary functions of the 5-HT system in the brain are to facilitate motor output and concurrently inhibit sensory information processing [33].
  • Because tonic conductances can be modulated by changes in GABA release and uptake, and by modulators of high-affinity GABAA receptors including neurosteroids, this phenomenon provides a potentially important new window onto neuronal information processing and pathological states such as epilepsy [34].
  • The steroid-mediated control of excitability and the implications for information processing in the brain are reviewed in this article [35].

Gene context of Automatic Data Processing

  • We close our review with speculations concerning how the complexities and idiosyncrasies of ERK regulation may allow for sophisticated information processing at the biochemical level in neurons-attributes that may make the ERK cascade well-suited for triggering complex and long-lasting behavioral change [36].
  • The ttx-3-dependent thermosensory pathway also couples to the temperature-modulated dauer neuroendocrine signaling pathway, showing that ttx-3 specifies AIY thermosensory information processing of both motor and autonomic outputs [37].
  • Association of the G1947A COMT (Val(108/158)Met) gene polymorphism with prefrontal P300 during information processing [38].
  • The results suggest that both AVP and OXT are signals in central pathways involved in information processing [39].
  • DRD4 related to infant attention and information processing: a developmental link to ADHD [40]?

Analytical, diagnostic and therapeutic context of Automatic Data Processing


  1. Visual evoked potentials during long periods of pattern-reversal stimulation in migraine. Afra, J., Cecchini, A.P., De Pasqua, V., Albert, A., Schoenen, J. Brain (1998) [Pubmed]
  2. Slowed information processing in multiple sclerosis. Litvan, I., Grafman, J., Vendrell, P., Martinez, J.M. Arch. Neurol. (1988) [Pubmed]
  3. Potentiation of GABA(A) currents after mechanical injury of cortical neurons. Kao, C.Q., Goforth, P.B., Ellis, E.F., Satin, L.S. J. Neurotrauma (2004) [Pubmed]
  4. Nitric oxide synthase in the thoracic ganglia of the locust: distribution in the neuropiles and morphology of neurones. Ott, S.R., Burrows, M. J. Comp. Neurol. (1998) [Pubmed]
  5. Acuity scores as predictors of cost-related outcomes of neonatal intensive care. Kotagal, U.R., Perlstein, P.H., Atherton, H.D., Donovan, E.F. J. Pediatr. (1995) [Pubmed]
  6. Modulatory role of serotonin in neural information processing: implications for human psychopathology. Spoont, M.R. Psychological bulletin. (1992) [Pubmed]
  7. Wisconsin Card Sorting Test performance in schizophrenia: remediation of a stubborn deficit. Green, M.F., Satz, P., Ganzell, S., Vaclav, J.F. The American journal of psychiatry. (1992) [Pubmed]
  8. Abnormal stimulus processing in posttraumatic stress disorder. McFarlane, A.C., Weber, D.L., Clark, C.R. Biol. Psychiatry (1993) [Pubmed]
  9. Sustained attention-deficit confirmed in euthymic bipolar disorder but not in first-degree relatives of bipolar patients or euthymic unipolar depression. Clark, L., Kempton, M.J., Scarnà, A., Grasby, P.M., Goodwin, G.M. Biol. Psychiatry (2005) [Pubmed]
  10. Enlarged frontal P300 to stimulus change in panic disorder. Clark, C.R., McFarlane, A.C., Weber, D.L., Battersby, M. Biol. Psychiatry (1996) [Pubmed]
  11. Vertebrate slit, a secreted ligand for the transmembrane protein roundabout, is a repellent for olfactory bulb axons. Li, H.S., Chen, J.H., Wu, W., Fagaly, T., Zhou, L., Yuan, W., Dupuis, S., Jiang, Z.H., Nash, W., Gick, C., Ornitz, D.M., Wu, J.Y., Rao, Y. Cell (1999) [Pubmed]
  12. The contribution of Shaker K+ channels to the information capacity of Drosophila photoreceptors. Niven, J.E., Vähäsöyrinki, M., Kauranen, M., Hardie, R.C., Juusola, M., Weckström, M. Nature (2003) [Pubmed]
  13. Hippocampal synaptic transmission enhanced by low concentrations of nicotine. Gray, R., Rajan, A.S., Radcliffe, K.A., Yakehiro, M., Dani, J.A. Nature (1996) [Pubmed]
  14. The role of NMDA receptors in information processing. Daw, N.W., Stein, P.S., Fox, K. Annu. Rev. Neurosci. (1993) [Pubmed]
  15. Brain corticosteroid receptor balance in health and disease. De Kloet, E.R., Vreugdenhil, E., Oitzl, M.S., Joëls, M. Endocr. Rev. (1998) [Pubmed]
  16. The effects of nicotine on attention, information processing, and short-term memory in patients with dementia of the Alzheimer type. Sahakian, B., Jones, G., Levy, R., Gray, J., Warburton, D. The British journal of psychiatry : the journal of mental science. (1989) [Pubmed]
  17. Does modafinil enhance cognitive performance in young volunteers who are not sleep-deprived? Randall, D.C., Viswanath, A., Bharania, P., Elsabagh, S.M., Hartley, D.E., Shneerson, J.M., File, S.E. Journal of clinical psychopharmacology. (2005) [Pubmed]
  18. Plasma cobalamin levels affect information processing speed in a longitudinal study of HIV-1 disease. Shor-Posner, G., Morgan, R., Wilkie, F., Eisdorfer, C., Baum, M.K. Arch. Neurol. (1995) [Pubmed]
  19. Blood glucose influences memory and attention in young adults. Benton, D., Owens, D.S., Parker, P.Y. Neuropsychologia. (1994) [Pubmed]
  20. Scopolamine and lorazepam exert different patterns of effects in a test battery assessing stages of information processing. Duka, T., Redemann, B., Voet, B. Psychopharmacology (Berl.) (1995) [Pubmed]
  21. Neural basis of genetically determined visuospatial construction deficit in Williams syndrome. Meyer-Lindenberg, A., Kohn, P., Mervis, C.B., Kippenhan, J.S., Olsen, R.K., Morris, C.A., Berman, K.F. Neuron (2004) [Pubmed]
  22. Subclasses of event-related potentials: response-locked and stimulus-locked components. Goodin, D.S., Aminoff, M.J., Mantle, M.M. Ann. Neurol. (1986) [Pubmed]
  23. DNA sequence-based "bar codes" for tracking the origins of expressed sequence tags from a maize cDNA library constructed using multiple mRNA sources. Qiu, F., Guo, L., Wen, T.J., Liu, F., Ashlock, D.A., Schnable, P.S. Plant Physiol. (2003) [Pubmed]
  24. Commentary on: "Effects of scopolamine and nicotine on human rapid information processing performance." Psychopharmacology (1984) 82:147-150. Nicotine improves information processing: saying the unthinkable. Warburton, D.M. Psychopharmacology (Berl.) (2002) [Pubmed]
  25. Evidence that 5'-nucleotidase is associated with malleable synapses--an enzyme cytochemical investigation of the olfactory bulb of adult rats. Schoen, S.W., Kreutzberg, G.W. Neuroscience (1995) [Pubmed]
  26. Spillover-mediated transmission at inhibitory synapses promoted by high affinity alpha6 subunit GABA(A) receptors and glomerular geometry. Rossi, D.J., Hamann, M. Neuron (1998) [Pubmed]
  27. Pre- and postnatal development of GABA receptors in Macaca monkey visual cortex. Shaw, C., Cameron, L., March, D., Cynader, M., Zielinski, B., Hendrickson, A. J. Neurosci. (1991) [Pubmed]
  28. Diurnal variation of cerebrospinal fluid immunoreactive corticotropin-releasing hormone levels in healthy volunteers. Kling, M.A., DeBellis, M.D., O'Rourke, D.K., Listwak, S.J., Geracioti, T.D., McCutcheon, I.E., Kalogeras, K.T., Oldfield, E.H., Gold, P.W. J. Clin. Endocrinol. Metab. (1994) [Pubmed]
  29. Electrical and chemical transmission between striatal GABAergic output neurones in rat brain slices. Venance, L., Glowinski, J., Giaume, C. J. Physiol. (Lond.) (2004) [Pubmed]
  30. Forebrain norepinephrine: role in controlled information processing in the rat. Cole, B.J., Robbins, T.W. Neuropsychopharmacology (1992) [Pubmed]
  31. Diversity of G proteins in signal transduction. Simon, M.I., Strathmann, M.P., Gautam, N. Science (1991) [Pubmed]
  32. The essence of excitation. Reimer, R.J., Fremeau, R.T., Bellocchio, E.E., Edwards, R.H. Curr. Opin. Cell Biol. (2001) [Pubmed]
  33. 5-HT and motor control: a hypothesis. Jacobs, B.L., Fornal, C.A. Trends Neurosci. (1993) [Pubmed]
  34. Tonically active GABA A receptors: modulating gain and maintaining the tone. Semyanov, A., Walker, M.C., Kullmann, D.M., Silver, R.A. Trends Neurosci. (2004) [Pubmed]
  35. Control of neuronal excitability by corticosteroid hormones. Joëls, M., de Kloet, E.R. Trends Neurosci. (1992) [Pubmed]
  36. Molecular psychology: roles for the ERK MAP kinase cascade in memory. Adams, J.P., Sweatt, J.D. Annu. Rev. Pharmacol. Toxicol. (2002) [Pubmed]
  37. Regulation of interneuron function in the C. elegans thermoregulatory pathway by the ttx-3 LIM homeobox gene. Hobert, O., Mori, I., Yamashita, Y., Honda, H., Ohshima, Y., Liu, Y., Ruvkun, G. Neuron (1997) [Pubmed]
  38. Association of the G1947A COMT (Val(108/158)Met) gene polymorphism with prefrontal P300 during information processing. Gallinat, J., Bajbouj, M., Sander, T., Schlattmann, P., Xu, K., Ferro, E.F., Goldman, D., Winterer, G. Biol. Psychiatry (2003) [Pubmed]
  39. Vasopressin and oxytocin in brain areas of rats with high or low behavioral performance. Ermisch, A., Landgraf, R., Möbius, P. Brain Res. (1986) [Pubmed]
  40. DRD4 related to infant attention and information processing: a developmental link to ADHD? Auerbach, J.G., Benjamin, J., Faroy, M., Geller, V., Ebstein, R. Psychiatr. Genet. (2001) [Pubmed]
  41. Hippocampal EEG and information processing: a special role for theta rhythm. Klemm, W.R. Prog. Neurobiol. (1976) [Pubmed]
  42. Three-month nutritional supplementation in Indonesian infants and toddlers benefits memory function 8 y later. Pollitt, E., Watkins, W.E., Husaini, M.A. Am. J. Clin. Nutr. (1997) [Pubmed]
  43. Ageing, serotonin and ketanserin. Breckenridge, A. Drugs (1988) [Pubmed]
  44. Quantitative comparison of planar and SPECT normal data files of thallium-201, technetium-99m-sestamibi, technetium-99m-tetrofosmin and technetium-99m-furifosmin. Naruse, H., Daher, E., Sinusas, A., Jain, D., Natale, D., Mattera, J., Makuch, R., Wackers, F.J. J. Nucl. Med. (1996) [Pubmed]
  45. White matter hyperintensities are related to physical disability and poor motor function. Sachdev, P.S., Wen, W., Christensen, H., Jorm, A.F. J. Neurol. Neurosurg. Psychiatr. (2005) [Pubmed]
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