Disease relevance of Fenton's reagent

• Optimization of the simultaneous chemical and biological mineralization of perchloroethylene (PCE) by modified Fenton's reagent and Xanthobacter flavus was investigated by using a central composite rotatable experimental design [1].
• Significant oxidation and mineralization of both biocides could be achieved employing ozonation at pH = 11.5 and heterogeneous photocatalysis (TiO2/UV-A) at pH = 5.0, whereas Fenton's reagent appeared to be less effective in COD and acute toxicity abatement [2].
• Application of Fenton's reagent (1% H2O2, 1 mM FeSO4) followed by inoculation with pure cultures Pseudomonas sp, strain LB 400 and Alcaligenes eutrophus, strain H850 resulted in the removal of approximately 38% of 2-chlorobiphenyl and 51% of 2,2',4,4'-tetrachlorobiphenyl in the form of 14CO2 [3].

Psychiatry related information on Fenton's reagent

• The effect of operating conditions such as reaction time, pH, H2O2 to Fe(II) molar ratio, Fenton's reagent dosage, initial COD strength, feeding mode, the type of polymer, and temperature on the efficacy of Fenton process was investigated [4].

High impact information on Fenton's reagent

• Intense lipid peroxidation of brain synaptosomes initiated with Fenton's reagent (H2O2 + Fe2+) began instantly upon addition of Fe2+ and preceded detectable OH. formation [5].
• Given the fact that methane has a relatively strong C-H bond (ca. 10 kcal/mol stronger than the C-H bonds in the more typical Fenton's reagent substrates), we infer that for many organic substrates oxidation with the ferryl ion as an active intermediate may be a perfectly viable route [6].
• To quantify antioxidative effects, a newly introduced test system based on the diminution of the ESR signal of DMPO-OH (generated by Fenton's reagent) by the tested compounds was applied [7].
• HO(*) was generated from Fenton's reagent (1. 5x10(-4)M H(2)O(2) plus 10(-4)M FeSO(4)); generation of HO(*) from H(2)O(2)/FeSO(4) in the superfusate was monitored by electron spin resonance spectroscopy using the spin-trap 5, 5-dimethyl-1-pyrroline-N-oxide throughout the experimental time course [8].
• We, therefore, investigated the role of oxygen-derived free radicals generated from Fenton's reagent (3 x 10(-4) M H2O2 plus 2 x 10(-4) M FeSO4) on CGRP-mediated neurogenic relaxation of canine lingual artery ring preparations [9].

Chemical compound and disease context of Fenton's reagent

• The effect of operating conditions such as reaction time, the distance between the electrodes, electrical current, H(2)O(2) to Fe(II) molar ratio, Fenton's reagent dosage and H(2)O(2) feeding mode on the efficacy of E-Fenton process was investigated [10].
• The effect of operating conditions such as reaction time, hydraulic retention time, pH, H(2)O(2) to Fe(II) molar ratio, Fenton's reagent dosage, initial COD strength, and temperature on the efficacy of Fenton process was investigated [11].

Biological context of Fenton's reagent

• Chemical pathway and kinetics of phenol oxidation by Fenton's reagent [12].
• Hydroxyl radicals that were formed in Fenton's reagent reacted with the organic substrate producing two different isomers of monohydroxylated product and, upon successive hydroxylation, mainly one dihydroxylated product [13].
• Furthermore, piperlactam S effectively minimized the loss of cell viability induced by Fenton's reagent (H2O2/FeSO4) in cultured endothelial cells and significantly reversed H2O2/FeSO4-induced impairment of endothelium-dependent relaxation to acetylcholine in rat aorta [14].
• A combination of SC-CO2 extraction and subsequent degradation by Fenton's reagent may provide an alternative water purification strategy for treating organophosphate pesticides in agro-wastewater [15].
• Heterogeneous photocatalysis coupled with the Fenton's reagent proved to have the lowest environmental impact accompanied with a moderate-to-high DOC removal rate [16].

Anatomical context of Fenton's reagent

• Free radical formation from ethanol and acetaldehyde was studied in the presence of a spin-trap and a NADPH generating system with a chemical model, Fenton's reagent, or by enzymatic oxidation of these solvents by rat liver and brain microsomes [17].
• A strongly immobilized signal appeared on exposure of erythrocytes to H2O2 but was not observed in either H2O2- or Fenton's reagent-treated ghosts or lipid vesicles prepared from H2O2-treated erythrocytes, indicating that the appearance of this signal necessitates the reaction of hemoglobin with H2O2 and is not due to lipid peroxidation [18].
• The inhibitory effect of aroma extracts isolated from dried soybeans, mung beans, kidney beans, and azuki beans on malonaldehyde (MA) formation from horse blood plasma oxidized with Fenton's reagent was determined by gas chromatography (GC) coupled with nitrogen-phosphorus detector (NPD) [19].
• To understand the effect of oxygen free radicals on Ca(2+)-ATPase, we used sarcoplasmic reticulum (SR) microsomes of canine masseter muscle as a model system in which to explore the effects of oxidation on a biological membrane, and we investigated the effect of hydroxyl radicals (.OH) generated from Fenton's reagent (H2O2/FeSO4) [20].
• Calf thymus DNA was oxidized by Fenton's reagent with or without synthetic antioxidants (Trolox and DMPO) and natural antioxidants-quercetin, apigenin, 2''-O-glycosylisovitexin (2''-O-GIV), (+)-catechin, cyanidin, pelargonidin, keracyanin, and callistephin [21].

Associations of Fenton's reagent with other chemical compounds

• Antioxidant effects of delta 8,9-dehydro derivatives of 17 alpha-estradiol and 17 beta-estradiol were investigated using four different in vitro models: rat synaptosomal lipid peroxidation induced by Fenton's reagent, Fe(II)-chelating activities, the formation of superoxide anion radicals, and total antioxidative activities [22].
• Cellobiose oxidase from Phanerochaete chrysosporium as a source of Fenton's reagent [23].
• Ethylene glycol removal was enhanced by exposure to UV light after treatment with Fenton's reagent, with rates dependent on initial H2O2 concentration [24].
• The antioxidant activities of naturally occurring plant compounds were measured in a lipid peroxidation system consisting of ethyl arachidonate and Fenton's reagent [25].
• The effect of operating parameters, such as UV, pH, amount of Fenton's reagent (H(2)O(2) and FeSO(4)), and amount of DY12 dye has also been determined [26].

Gene context of Fenton's reagent

• Further, an increased susceptibility of the apo B-containing lipoproteins (LDL+VLDL) to oxidation in vitro, induced by copper ions and Fenton's reagent, was observed in the untreated CCT diet fed group [27].
• The first was a chemical model using Fenton's reagent, a mixture of Fe(II)-chelator and H2O2, for which the normal reaction is OH. production, and the second, a preparation from rat liver and brain microsomes containing NADPH and achieving enzymatic oxidation of the solvents [28].
• Effect of sequestration on PAH degradability with Fenton's reagent: roles of total organic carbon, humin, and soil porosity [29].
• Approximately, 88% TOC, 85% color and 89% AOX removals were obtained by the Fenton's reagent at pH 5 within 30min [30].
• Incubation of Trypanosoma cruzi mitochondrial ATPase (Fo-F1) with the xanthine oxidase system (XO), Fenton's reagent (Fe2+ + H2O2) and the ascorbate-Cu system, caused gradual loss of enzyme activity, which increased as a function of incubation time and rate of oxygen radical generation [31].

Analytical, diagnostic and therapeutic context of Fenton's reagent

• The specific filtration resistance, moisture, and SVI were used to evaluate the influence of pH on the filtration and dewatering efficiencies when applying Fenton's reagent to treat the excess sludge [32].

References