Chemical Compound Review:
D-NAME methyl(2R)-2-amino-5-[(amino- nitramido...
Synonyms:
AmbotzHAA5760, Lopac-N-5751, ZINC19594743, AR-1J6502, LS-183875, ...
- Hypotension and inflammatory cytokine gene expression triggered by factor Xa-nitric oxide signaling. Papapetropoulos, A., Piccardoni, P., Cirino, G., Bucci, M., Sorrentino, R., Cicala, C., Johnson, K., Zachariou, V., Sessa, W.C., Altieri, D.C. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Essential role for nitric oxide in neurogenic inflammation in rat cutaneous microcirculation. Evidence for an endothelium-independent mechanism. Kajekar, R., Moore, P.K., Brain, S.D. Circ. Res. (1995)
- Statins enhance postischemic hyperemia in the skin circulation of hypercholesterolemic patients: a monitoring test of endothelial dysfunction for clinical practice? Binggeli, C., Spieker, L.E., Corti, R., Sudano, I., Stojanovic, V., Hayoz, D., Lüscher, T.F., Noll, G. J. Am. Coll. Cardiol. (2003)
- Nitric oxide is required for effective innate immunity against Klebsiella pneumoniae. Tsai, W.C., Strieter, R.M., Zisman, D.A., Wilkowski, J.M., Bucknell, K.A., Chen, G.H., Standiford, T.J. Infect. Immun. (1997)
- Effect of chronic nitric oxide synthesis inhibition on the inflammatory responses induced by carrageenin in rats. Medeiros, M.V., Binhara, I.M., Moreno Júnior, H., Zatz, R., De Nucci, G., Antunes, E. Eur. J. Pharmacol. (1995)
- Implication of a nitric oxide synthase mechanism in the action of substance P: L-NAME blocks thermal hyperalgesia induced by endogenous and exogenous substance P in the rat. Radhakrishnan, V., Yashpal, K., Hui-Chan, C.W., Henry, J.L. Eur. J. Neurosci. (1995)
- Nitric oxide promotes medial preoptic dopamine release during male rat copulation. Lorrain, D.S., Matuszewich, L., Howard, R.V., Du, J., Hull, E.M. Neuroreport (1996)
- Inhibition of nitric oxide synthesis with L-NAME suppresses isolation-induced ultrasounds in rat pups. Campbell, J.O., Fogarty, J.A., Spear, L.P. Pharmacol. Biochem. Behav. (1999)
- Pharmacological and immunohistochemical evidence for a functional nitric oxide synthase system in rat peritoneal eosinophils. Zanardo, R.C., Costa, E., Ferreira, H.H., Antunes, E., Martins, A.R., Murad, F., De Nucci, G. Proc. Natl. Acad. Sci. U.S.A. (1997)
- Superoxide generation from endothelial nitric-oxide synthase. A Ca2+/calmodulin-dependent and tetrahydrobiopterin regulatory process. Xia, Y., Tsai, A.L., Berka, V., Zweier, J.L. J. Biol. Chem. (1998)
- Nitric oxide mediates angiogenesis induced in vivo by platelet-activating factor and tumor necrosis factor-alpha. Montrucchio, G., Lupia, E., de Martino, A., Battaglia, E., Arese, M., Tizzani, A., Bussolino, F., Camussi, G. Am. J. Pathol. (1997)
- Role of endothelial nitric oxide synthase in endothelial cell migration. Murohara, T., Witzenbichler, B., Spyridopoulos, I., Asahara, T., Ding, B., Sullivan, A., Losordo, D.W., Isner, J.M. Arterioscler. Thromb. Vasc. Biol. (1999)
- Endothelin inhibits thick ascending limb chloride flux via ET(B) receptor-mediated NO release. Plato, C.F., Pollock, D.M., Garvin, J.L. Am. J. Physiol. Renal Physiol. (2000)
- Involvement of nitric oxide in 2-deoxy-D-glucose-induced hyperphagia in rats. Yamada, J., Sugimoto, Y., Yoshikawa, T., Horisaka, K. Neuroreport (1997)
- L-NG-nitro arginine methyl ester exhibits antinociceptive activity in the mouse. Moore, P.K., Oluyomi, A.O., Babbedge, R.C., Wallace, P., Hart, S.L. Br. J. Pharmacol. (1991)
- Regulation of NANC neural bronchoconstriction in vivo in the guinea-pig: involvement of nitric oxide, vasoactive intestinal peptide and soluble guanylyl cyclase. Lei, Y.H., Barnes, P.J., Rogers, D.F. Br. J. Pharmacol. (1993)
- Cardiac sympathetic overactivity and decreased baroreflex sensitivity in L-NAME hypertensive rats. Souza, H.C., Ballejo, G., Salgado, M.C., Da Silva, V.J., Salgado, H.C. Am. J. Physiol. Heart Circ. Physiol. (2001)
- Canine hindlimb blood flow and O2 uptake after inhibition of EDRF/NO synthesis. King, C.E., Melinyshyn, M.J., Mewburn, J.D., Curtis, S.E., Winn, M.J., Cain, S.M., Chapler, C.K. J. Appl. Physiol. (1994)
- Role of nitric oxide and platelet-activating factor in cardiac alterations induced by tumor necrosis factor-alpha in the guinea-pig papillary muscle. Alloatti, G., Penna, C., De Martino, A., Montrucchio, G., Camussi, G. Cardiovasc. Res. (1999)
- Mutual regulation between the intercellular messengers nitric oxide and brain-derived neurotrophic factor in rodent neocortical neurons. Xiong, H., Yamada, K., Han, D., Nabeshima, T., Enikolopov, G., Carnahan, J., Nawa, H. Eur. J. Neurosci. (1999)
- L-NAME protects against acute light damage in albino rats, but not against retinal degeneration in P23H and S334ter transgenic rats. Káldi, I., Dittmar, M., Pierce, P., Anderson, R.E. Exp. Eye Res. (2003)
- Deficits in working memory following inhibition of hippocampal nitric oxide synthesis in the rat. Ohno, M., Yamamoto, T., Watanabe, S. Brain Res. (1993)
- A nitric oxide synthesis inhibitor (L-NAME) reduces licking behavior and Fos-labeling in the spinal cord of rats during formalin-induced inflammation. Roche, A.K., Cook, M., Wilcox, G.L., Kajander, K.C. Pain (1996)
- Significance of nitric oxide in the stimulation of intestinal fluid absorption in the rat jejunum in vivo. Schirgi-Degen, A., Beubler, E. Br. J. Pharmacol. (1995)
- Role of nitric oxide in rat locus coeruleus in hypoxia-induced hyperventilation and hypothermia. Fabris, G., Steiner, A.A., Anselmo-Franci, J.A., Branco, L.G. Neuroreport (2000)
- Endogenous vasoactive intestinal peptide and nitric oxide modulate cholinergic neurotransmission in guinea-pig trachea. Belvisi, M.G., Miura, M., Stretton, D., Barnes, P.J. Eur. J. Pharmacol. (1993)
- Attenuation of the exercise-induced increase in skeletal muscle Flt-1 mRNA by nitric oxide synthase inhibition. Gavin, T.P., Wagner, P.D. Acta Physiol. Scand. (2002)
- Antioxidant levels in the rat brain after nitric oxide synthase inhibition: a preliminary report. Barthwal, M.K., Srivastava, N., Nag, D., Seth, P.K., Srimal, R.C., Dikshit, M. Redox Rep. (2000)
- Constitutively synthesized nitric oxide is a physiological negative regulator of mammalian angiogenesis mediated by basic fibroblast growth factor. Norrby, K. International journal of experimental pathology. (2000)
- Nitric oxide-dependent and -independent hyperaemia due to calcitonin gene-related peptide in the rat stomach. Holzer, P., Lippe, I.T., Jocic, M., Wachter, C., Erb, R., Heinemann, A. Br. J. Pharmacol. (1993)
- Pressor and sympathoexcitatory effects of nitric oxide in the rostral ventrolateral medulla. Hirooka, Y., Polson, J.W., Dampney, R.A. J. Hypertens. (1996)
- Amelioration of chronic ileitis by nitric oxide synthase inhibition. Miller, M.J., Sadowska-Krowicka, H., Chotinaruemol, S., Kakkis, J.L., Clark, D.A. J. Pharmacol. Exp. Ther. (1993)
- Intrahippocampal administration of the NO synthase inhibitor L-NAME prevents working memory deficits in rats exposed to transient cerebral ischemia. Ohno, M., Yamamoto, T., Watanabe, S. Brain Res. (1994)
- Participation of nitric oxide in the mustard oil-induced neurogenic inflammation of the rat paw skin. Lippe, I.T., Stabentheiner, A., Holzer, P. Eur. J. Pharmacol. (1993)