The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

dnqx     6,7-dinitro-1,4- dihydroquinoxaline-2,3-dione

Synonyms: Lopac-D-0540, Tocris-0189, AC1MZKE9, AG-E-69885, D0540_SIGMA, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of dnqx


Psychiatry related information on dnqx


High impact information on dnqx


Biological context of dnqx


Anatomical context of dnqx


Associations of dnqx with other chemical compounds


Gene context of dnqx


Analytical, diagnostic and therapeutic context of dnqx


  1. Chronological atrophy after transient middle cerebral artery occlusion in rats. Hara, H., Harada, K., Sukamoto, T. Brain Res. (1993) [Pubmed]
  2. Modulation of glutamate agonist-induced influx of calcium into neurons by gamma-L-glutamyl and beta-L-aspartyl dipeptides. Varga, V., Janáky, R., Oja, S.S. Neurosci. Lett. (1992) [Pubmed]
  3. AMPA, kainic acid, and N-methyl-D-aspartic acid stimulate locomotor activity after injection into the substantia innominata/lateral preoptic area. Shreve, P.E., Uretsky, N.J. Pharmacol. Biochem. Behav. (1989) [Pubmed]
  4. mRNA coding for neurotransmitter receptors in a human astrocytoma. Matute, C., Arellano, R.O., Conde-Guerri, B., Miledi, R. Proc. Natl. Acad. Sci. U.S.A. (1992) [Pubmed]
  5. Presynaptic inhibition of excitatory synaptic transmission by adenosine in rat hippocampus: analysis of unitary EPSP variance measured by whole-cell recording. Lupica, C.R., Proctor, W.R., Dunwiddie, T.V. J. Neurosci. (1992) [Pubmed]
  6. NMDA receptor-mediated synaptic excitation selectively inhibited by ethanol in hippocampal slice from adult rat. Lovinger, D.M., White, G., Weight, F.F. J. Neurosci. (1990) [Pubmed]
  7. Indirect modulation by alpha7 nicotinic acetylcholine receptors of noradrenaline release in rat hippocampal slices: interaction with glutamate and GABA systems and effect of nicotine withdrawal. Barik, J., Wonnacott, S. Mol. Pharmacol. (2006) [Pubmed]
  8. Glutamatergic synaptic transmission participates in generating the hippocampal EEG. Leung, L.S., Shen, B. Hippocampus. (2004) [Pubmed]
  9. Changes in mIPSCs and sIPSCs after kainate treatment: evidence for loss of inhibitory input to dentate granule cells and possible compensatory responses. Shao, L.R., Dudek, F.E. J. Neurophysiol. (2005) [Pubmed]
  10. Neurons generated from adult rat hippocampal stem cells form functional glutamatergic and GABAergic synapses in vitro. Toda, H., Takahashi, J., Mizoguchi, A., Koyano, K., Hashimoto, N. Exp. Neurol. (2000) [Pubmed]
  11. Blockade of AMPA/kainate receptors can either decrease or increase the survival of cultured neocortical cells depending on the stage of maturation. Drian, M.J., Bardoul, M., König, N. Neurochem. Int. (2001) [Pubmed]
  12. Developmental time course and ionic dependence of kainate-mediated toxicity in rat cerebellar granule cell cultures. Kato, K., Puttfarcken, P.S., Lyons, W.E., Coyle, J.T. J. Pharmacol. Exp. Ther. (1991) [Pubmed]
  13. Comparison of ethanol sensitivity of rat brain kainate, DL-alpha-amino-3-hydroxy-5-methyl-4-isoxalone proprionic acid and N-methyl-D-aspartate receptors expressed in Xenopus oocytes. Dildy-Mayfield, J.E., Harris, R.A. J. Pharmacol. Exp. Ther. (1992) [Pubmed]
  14. Influence of AMPA/kainate receptors on extracellular 5-hydroxytryptamine in rat midbrain raphe and forebrain. Tao, R., Ma, Z., Auerbach, S.B. Br. J. Pharmacol. (1997) [Pubmed]
  15. Plasticity in an electrosensory system. I. General features of a dynamic sensory filter. Bastian, J. J. Neurophysiol. (1996) [Pubmed]
  16. Differential effect of ethanol on NMDA EPSCs in pyramidal cells in the posterior cingulate cortex of juvenile and adult rats. Li, Q., Wilson, W.A., Swartzwelder, H.S. J. Neurophysiol. (2002) [Pubmed]
  17. The release of amino acids from rat neostriatum and substantia nigra in vivo: a dual microdialysis probe analysis. Bianchi, L., Colivicchi, M.A., Bolam, J.P., Della Corte, L. Neuroscience (1998) [Pubmed]
  18. Alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid electrophysiological and neurotoxic effects in the guinea-pig cochlea. Puel, J.L., Pujol, R., Ladrech, S., Eybalin, M. Neuroscience (1991) [Pubmed]
  19. Endogenous glutamate increases extracellular concentrations of dopamine, GABA, and taurine through NMDA and AMPA/kainate receptors in striatum of the freely moving rat: a microdialysis study. Segovia, G., Del Arco, A., Mora, F. J. Neurochem. (1997) [Pubmed]
  20. Investigations into the adenosine outflow from hippocampal slices evoked by ischemia-like conditions. Pedata, F., Latini, S., Pugliese, A.M., Pepeu, G. J. Neurochem. (1993) [Pubmed]
  21. Electrophysiology and pharmacology of projections from the suprachiasmatic nucleus to the ventromedial preoptic area in rat. Sun, X., Rusak, B., Semba, K. Neuroscience (2000) [Pubmed]
  22. Differential contributions of NMDA and non-NMDA receptors to spinal Fos expression evoked by superficial tissue and muscle inflammation in the rat. Hu, J.Y., Zhao, Z.Q. Neuroscience (2001) [Pubmed]
  23. N-methyl-D-aspartate receptors at parallel fiber synapses in the dorsal cochlear nucleus. Manis, P.B., Molitor, S.C. J. Neurophysiol. (1996) [Pubmed]
  24. Somatostatin potently stimulates in vivo striatal dopamine and gamma-aminobutyric acid release by a glutamate-dependent action. Hathway, G.J., Emson, P.C., Humphrey, P.P., Kendrick, K.M. J. Neurochem. (1998) [Pubmed]
  25. Mechanisms of regulation of tyrosine phosphorylation of NMDA receptor subunit 2B after cerebral ischemia/reperfusion. Pei, L., Li, Y., Zhang, G.Y., Cui, Z.C., Zhu, Z.M. Acta Pharmacol. Sin. (2000) [Pubmed]
  26. The expression pattern of somatostatin and calretinin by postnatal hippocampal interneurons is regulated by activity-dependent and -independent determinants. Marty, S., Onténiente, B. Neuroscience (1997) [Pubmed]
  27. Antagonism of monosynaptic excitations in the mouse olfactory cortex slice by 6,7-dinitroquinoxaline-2,3-dione. Collins, G.G., Buckley, K.S. Neuropharmacology (1989) [Pubmed]
  28. Hyperpolarizing and depolarizing GABAA receptor-mediated dendritic inhibition in area CA1 of the rat hippocampus. Lambert, N.A., Borroni, A.M., Grover, L.M., Teyler, T.J. J. Neurophysiol. (1991) [Pubmed]
  29. NMDA receptor blockade increases in vivo striatal dopamine synthesis and release in rats and mice with incomplete, dopamine-depleting, nigrostriatal lesions. Richard, M.G., Bennett, J.P. J. Neurochem. (1995) [Pubmed]
  30. Mechanisms underlying LTP of inhibitory synaptic transmission in the deep cerebellar nuclei. Ouardouz, M., Sastry, B.R. J. Neurophysiol. (2000) [Pubmed]
  31. Effects of vestibular stimulation on acetylcholine release from rat hippocampus: an in vivo microdialysis study. Horii, A., Takeda, N., Mochizuki, T., Okakura-Mochizuki, K., Yamamoto, Y., Yamatodani, A. J. Neurophysiol. (1994) [Pubmed]
  32. Spinal cord excitatory amino acids and cardiovascular autonomic responses. West, M., Huang, W. Am. J. Physiol. (1994) [Pubmed]
  33. The opioid system and excitatory amino acids in the onset of puberty in female rats. Mena-Valdivia, M.A., Nava-Espinosa, L.E., Malacara-Hernández, J.M. Arch. Med. Res. (1995) [Pubmed]
WikiGenes - Universities