Gene Review:
Sstr2 - somatostatin receptor 2
Rattus norvegicus
Synonyms:
SRIF-1, SS-2-R, SS2-R, SS2R, Somatostatin receptor type 2
- Luteinising hormone-releasing and anti-fertility properties of a glucagon-selective somatostatin analogue. Bex, F.J., Corbin, A., Sarantakis, D., Lien, E. Nature (1980)
- Identification and quantification of Gi-type GTP-binding proteins that copurify with a pituitary somatostatin receptor. Luthin, D.R., Eppler, C.M., Linden, J. J. Biol. Chem. (1993)
- Structural analysis and functional role of the carbohydrate component of somatostatin receptors. Rens-Domiano, S., Reisine, T. J. Biol. Chem. (1991)
- The processing of receptor-bound [125I-Tyr11]somatostatin by RINm5F insulinoma cells. Sullivan, S.J., Schonbrunn, A. J. Biol. Chem. (1986)
- Hypersection of pancreatic somatostatin in the obese Zucker rat: effects of food restriction and age. Trimble, E.R., Herberg, L., Renold, A.E. Diabetes (1980)
- Somatostatin receptors in the nucleus accumbens selectively mediate the stimulatory effect of somatostatin on locomotor activity in rats. Raynor, K., Lucki, I., Reisine, T. J. Pharmacol. Exp. Ther. (1993)
- Granulocyte-macrophage colony-stimulating factor modulates rapid eye movement (REM) sleep and non-REM sleep in rats. Kimura, M., Kodama, T., Aguila, M.C., Zhang, S.Q., Inoue, S. J. Neurosci. (2000)
- Trophic effects of somatostatin on calcium flux: dynamic analysis and correlation with pituitary hormone release. Login, I.S., Judd, A.M. Endocrinology (1986)
- Somatostatin release as measured by in vivo microdialysis: circadian variation and effect of prolonged food deprivation. Ishikawa, M., Mizobuchi, M., Takahashi, H., Bando, H., Saito, S. Brain Res. (1997)
- Sleep deprivation increases somatostatin and growth hormone-releasing hormone messenger RNA in the rat hypothalamus. Toppila, J., Alanko, L., Asikainen, M., Tobler, I., Stenberg, D., Porkka-Heiskanen, T. Journal of sleep research. (1997)
- Skeletal muscle glycogenolysis is more sensitive to insulin than is glucose transport/phosphorylation. Relation to the insulin-mediated inhibition of hepatic glucose production. Rossetti, L., Hu, M. J. Clin. Invest. (1993)
- Decreased hypothalamic growth hormone-releasing hormone content and pituitary responsiveness in hypothyroidism. Katakami, H., Downs, T.R., Frohman, L.A. J. Clin. Invest. (1986)
- Ca2+ channel and adenylyl cyclase modulation by cloned mu-opioid receptors in GH3 cells. Piros, E.T., Prather, P.L., Loh, H.H., Law, P.Y., Evans, C.J., Hales, T.G. Mol. Pharmacol. (1995)
- Glucopenia-mediated release of somatostatin from incubated rat hypothalamus: monosaccharide specificity and role of glycolytic intermediates. Berelowitz, M., Ting, N.C., Murray, L. Endocrinology (1989)
- Somatostatin-14 and its analog octreotide exert a cytostatic effect on GH3 rat pituitary tumor cell proliferation via a transient G0/G1 cell cycle block. Cheung, N.W., Boyages, S.C. Endocrinology (1995)
- Somatostatin receptors mediating inhibition of basal and stimulated electrogenic ion transport in rat isolated distal colonic mucosa. McKeen, E.S., Feniuk, W., Humphrey, P.P. Naunyn Schmiedebergs Arch. Pharmacol. (1995)
- The somatostatin receptor subtype on rat enterochromaffinlike cells. Prinz, C., Sachs, G., Walsh, J.H., Coy, D.H., Wu, S.V. Gastroenterology (1994)
- Retrovirus-mediated expression of preprosomatostatin: posttranslational processing, intracellular storage, and secretion in GH3 pituitary cells. Stoller, T.J., Shields, D. J. Cell Biol. (1988)
- Expression cloning of a rat brain somatostatin receptor cDNA. Kluxen, F.W., Bruns, C., Lübbert, H. Proc. Natl. Acad. Sci. U.S.A. (1992)
- Targeting sst2A receptor-expressing cells in the rat hypothalamus through in vivo agonist stimulation: neuroanatomical evidence for a major role of this subtype in mediating somatostatin functions. Csaba, Z., Simon, A., Helboe, L., Epelbaum, J., Dournaud, P. Endocrinology (2003)
- Analogues of somatostatin bind selectively to brain somatostatin receptor subtypes. Raynor, K., Coy, D.C., Reisine, T. J. Neurochem. (1992)
- Somatostatin sst2 receptor-mediated inhibition of parietal cell function in rat isolated gastric mucosa. Wyatt, M.A., Jarvie, E., Feniuk, W., Humphrey, P.P. Br. J. Pharmacol. (1996)
- Evidence that somatostatin sst2 receptors mediate striatal dopamine release. Hathway, G.J., Humphrey, P.P., Kendrick, K.M. Br. J. Pharmacol. (1999)
- Colocalization of somatostatin receptors and growth hormone-releasing factor immunoreactivity in neurons of the rat arcuate nucleus. McCarthy, G.F., Beaudet, A., Tannenbaum, G.S. Neuroendocrinology (1992)
- Somatostatin receptor subtype 1 (sst(1)) regulates intracellular 3',5'-cyclic adenosine monophosphate accumulation in rat embryonic cortical neurons: evidence with L-797,591, an sst(1)-subtype-selective nonpeptidyl agonist. Blake, A.D. Neuropharmacology (2001)
- Muscarinic receptor activity change after prolonged treatment with growth hormone and somatostatin. Popova, J., Robeva, A., Zaharieva, S. Comp. Biochem. Physiol. C, Comp. Pharmacol. Toxicol. (1990)
- Immunohistochemical markers in rat cortex: co-localization of calretinin and calbindin-D28k with neuropeptides and GABA. Rogers, J.H. Brain Res. (1992)
- Growth hormone-releasing hormone neurons in the arcuate nucleus express both Sst1 and Sst2 somatostatin receptor genes. Tannenbaum, G.S., Zhang, W.H., Lapointe, M., Zeitler, P., Beaudet, A. Endocrinology (1998)
- Somatostatin inhibits vasoactive intestinal peptide-stimulated cyclic adenosine monophosphate accumulation in GH pituitary cells. Dorflinger, L.J., Schonbrunn, A. Endocrinology (1983)
- Stimulation of growth hormone secretion by central administration of atrial natriuretic polypeptide in the rat. Murakami, Y., Kato, Y., Tojo, K., Inoue, T., Yanaihara, N., Imura, H. Endocrinology (1988)
- Somatostatin potentiates NMDA receptor function via activation of InsP(3) receptors and PKC leading to removal of the Mg(2+) block without depolarization. Pittaluga, A., Bonfanti, A., Raiteri, M. Br. J. Pharmacol. (2000)
- Somatostatin and the somatostatin receptor 2 are reciprocally controlled by calcineurin during cerebellar granule cell maturation. Kramer, D., Caruso, A., Nicoletti, F., Genazzani, A.A. J. Neurochem. (2005)
- Growth hormone-releasing factor increases somatostatin release and mRNA levels in the rat periventricular nucleus via nitric oxide by activation of guanylate cyclase. Aguila, M.C. Proc. Natl. Acad. Sci. U.S.A. (1994)
- Pertussis toxin blocks the inhibitory effects of somatostatin on cAMP-dependent vasoactive intestinal peptide and cAMP-independent thyrotropin releasing hormone-stimulated prolactin secretion of GH3 cells. Yajima, Y., Akita, Y., Saito, T. J. Biol. Chem. (1986)
- Noradrenergic innervation of peptidergic interneurons in the rat visual cortex. Paspalas, C.D., Papadopoulos, G.C. Cereb. Cortex (1999)
- Development of antibodies against the rat brain somatostatin receptor. Theveniau, M., Rens-Domiano, S., Law, S.F., Rougon, G., Reisine, T. Proc. Natl. Acad. Sci. U.S.A. (1992)
- Somatostatin-induced regulation of SST(2A) receptor expression and cellsurface availability in central neurons: role of receptor internalization. Boudin, H., Sarret, P., Mazella, J., Schonbrunn, A., Beaudet, A. J. Neurosci. (2000)
- Reversal of somatostatin inhibition of insulin and glucagon secretion. Bhathena, S.J., Perrino, P.V., Voyles, N.R., Smith, S.S., Wilkins, S.D., Coy, D.H., Schally, A.V., Recant, L. Diabetes (1976)