Chemical Compound Review:
Galangin 3,5,7-trihydroxy-2-phenyl- chromen-4-one
Synonyms:
Norizalpinin, teptochrysin, PubChem9856, AC1NQYQM, CHEMBL309490, ...
Dambros,
de Jongh,
van Koeveringe,
van Deutekom,
De Mey,
Palma,
van Kerrebroeck,
Denny,
Lambert,
West,
Cipák,
Berczeliová,
Paulíková,
Heo,
Sohn,
Au,
Bestwick,
Milne,
van Zanden,
Geraets,
Wortelboer,
van Bladeren,
Rietjens,
Cnubben,
Capasso,
Fiorino,
Ascione,
Frecentese,
Borrelli,
Dambros,
de Jongh,
van Koeveringe,
Bast,
van Kerrebroeck,
- Antigenotoxicity of galangin against N-methyl-N-nitrosourea. Sohn, S.J., Huh, I.H., Au, W.W., Heo, M.Y. Mutat. Res. (1998)
- Anticlastogenic effects of galangin against bleomycin-induced chromosomal aberrations in mouse spleen lymphocytes. Heo, M.Y., Lee, S.J., Kwon, C.H., Kim, S.W., Sohn, D.H., Au, W.W. Mutat. Res. (1994)
- Vancomycin resistance reversal in enterococci by flavonoids. Liu, L.X., Durham, D.G., Richards, R.M. J. Pharm. Pharmacol. (2001)
- Galangin expresses bactericidal activity against multiple-resistant bacteria: MRSA, Enterococcus spp. and Pseudomonas aeruginosa. Pepeljnjak, S., Kosalec, I. FEMS Microbiol. Lett. (2004)
- Combinatorial biosynthesis of flavones and flavonols in Escherichia coli. Miyahisa, I., Funa, N., Ohnishi, Y., Martens, S., Moriguchi, T., Horinouchi, S. Appl. Microbiol. Biotechnol. (2006)
- Flavonol-stimulated efflux of 7,12-dimethylbenz(a)anthracene in multidrug-resistant breast cancer cells. Phang, J.M., Poore, C.M., Lopaczynska, J., Yeh, G.C. Cancer Res. (1993)
- The bioflavonoid galangin blocks aryl hydrocarbon receptor activation and polycyclic aromatic hydrocarbon-induced pre-B cell apoptosis. Quadri, S.A., Qadri, A.N., Hahn, M.E., Mann, K.K., Sherr, D.H. Mol. Pharmacol. (2000)
- Interactions of flavonoids and other phytochemicals with adenosine receptors. Ji, X.D., Melman, N., Jacobson, K.A. J. Med. Chem. (1996)
- Structural requirements for the flavonoid-mediated modulation of glutathione S-transferase P1-1 and GS-X pump activity in MCF7 breast cancer cells. van Zanden, J.J., Geraets, L., Wortelboer, H.M., van Bladeren, P.J., Rietjens, I.M., Cnubben, N.H. Biochem. Pharmacol. (2004)
- Effects of flavonoids on glutathione and glutathione-related enzymes in cisplatin-treated L1210 leukemia cells. Cipák, L., Berczeliová, E., Paulíková, H. Neoplasma (2003)
- Galangin protects pig detrusor nerves from repetitive field stimulation and anoxia/glucopenia injury. Dambros, M., de Jongh, R., van Koeveringe, G.A., Bast, A., van Kerrebroeck, P.E. Urology (2005)
- Dietary flavonoids: effects on xenobiotic and carcinogen metabolism. Moon, Y.J., Wang, X., Morris, M.E. Toxicology in vitro : an international journal published in association with BIBRA. (2006)
- Assessment of the antibacterial activity of selected flavonoids and consideration of discrepancies between previous reports. Cushnie, T.P., Hamilton, V.E., Lamb, A.J. Microbiol. Res. (2003)
- The flavonoid galangin is an inhibitor of CYP1A1 activity and an agonist/antagonist of the aryl hydrocarbon receptor. Ciolino, H.P., Yeh, G.C. Br. J. Cancer (1999)
- Flavonoids, potent inhibitors of the human P-form phenolsulfotransferase. Potential role in drug metabolism and chemoprevention. Eaton, E.A., Walle, U.K., Lewis, A.J., Hudson, T., Wilson, A.A., Walle, T. Drug Metab. Dispos. (1996)
- The flavonoid galangin inhibits the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia. Denny, B.J., Lambert, P.A., West, P.W. FEMS Microbiol. Lett. (2002)
- Influence of galangin on HL-60 cell proliferation and survival. Bestwick, C.S., Milne, L. Cancer Lett. (2006)
- Multiple-signaling pathways are involved in the inhibitory effects of galangin on urinary bladder contractility. Dambros, M., de Jongh, R., van Koeveringe, G.A., van Deutekom, M., De Mey, J.G., Palma, P.C., van Kerrebroeck, P.E. Neurourology and urodynamics. (2005)
- Anticlastogenic effects of galangin against mitomycin C-induced micronuclei in reticulocytes of mice. Heo, M.Y., Jae, L.H., Jung, S.S., Au, W.W. Mutat. Res. (1996)
- Glucuronidation versus oxidation of the flavonoid galangin by human liver microsomes and hepatocytes. Otake, Y., Hsieh, F., Walle, T. Drug Metab. Dispos. (2002)
- In vivo exposure to plant flavonols. Influence on frequencies of micronuclei in mouse erythrocytes and sister-chromatid exchange in rabbit lymphocytes. MacGregor, J.T., Wehr, C.M., Manners, G.D., Jurd, L., Minkler, J.L., Carrano, A.V. Mutat. Res. (1983)
- Interaction of organotins with a vacuolar-type H(+)-ATPase. Apps, D.K., Webster, L.C. Biochem. Biophys. Res. Commun. (1996)
- Biochemical studies of a new class of alcohol dehydrogenase inhibitors from Radix puerariae. Keung, W.M. Alcohol. Clin. Exp. Res. (1993)
- Inhibition of rat vas deferens contractions by flavonoids in-vitro. Capasso, R., Fiorino, F., Ascione, V., Frecentese, F., Borrelli, F. J. Pharm. Pharmacol. (2006)
- Comparative inhibition of human cytochromes P450 1A1 and 1A2 by flavonoids. Zhai, S., Dai, R., Friedman, F.K., Vestal, R.E. Drug Metab. Dispos. (1998)
- Effects of ethanol extract of propolis (EEP) and its flavones on inducible gene expression in J774A.1 macrophages. Blonska, M., Bronikowska, J., Pietsz, G., Czuba, Z.P., Scheller, S., Krol, W. Journal of ethnopharmacology. (2004)
- Anti-genotoxicity of galangin as a cancer chemopreventive agent candidate. Heo, M.Y., Sohn, S.J., Au, W.W. Mutat. Res. (2001)
- In vitro activity of propolis against Streptococcus pyogenes. Bosio, K., Avanzini, C., D'Avolio, A., Ozino, O., Savoia, D. Lett. Appl. Microbiol. (2000)