The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

Mykocert     acridin-9-amine

Synonyms: Monacrin, Aminacrin, Aminopt, Aminacrine, Izoacridina, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Aminacrine


Psychiatry related information on Aminacrine


High impact information on Aminacrine


Chemical compound and disease context of Aminacrine


Biological context of Aminacrine


Anatomical context of Aminacrine


Associations of Aminacrine with other chemical compounds


Gene context of Aminacrine


Analytical, diagnostic and therapeutic context of Aminacrine


  1. Identification of the 9-aminoacridine/DNA complex responsible for photodynamic inactivation of P22. Loechler, E.L., King, J. Biochemistry (1986) [Pubmed]
  2. Molecular mechanisms of chemical mutagenesis: 9-aminoacridine inhibits DNA replication in vitro by destabilizing the DNA growing point and interacting with the DNA polymerase. Topal, M.D. Biochemistry (1984) [Pubmed]
  3. The behavior of 9-aminoacridine as an indicator of transmembrane pH difference in liposomes of natural bacterial phospholipids. Casadio, R., Melandri, B.A. J. Bioenerg. Biomembr. (1977) [Pubmed]
  4. Lasalocid-catalyzed proton conductance in Streptococcus bovis as affected by extracellular potassium. Schwingel, W.R., Bates, D.B., Denham, S.C., Beede, D.K. Appl. Environ. Microbiol. (1989) [Pubmed]
  5. In-vitro photobactericidal activity of aminoacridines. Wainwright, M., Phoenix, D.A., Marland, J., Wareing, D.R., Bolton, F.J. J. Antimicrob. Chemother. (1997) [Pubmed]
  6. The 'delta pH'-probe 9-aminoacridine: response time, binding behaviour and dimerization at the membrane. Grzesiek, S., Dencher, N.A. Biochim. Biophys. Acta (1988) [Pubmed]
  7. Alkalinizing the intralysosomal pH inhibits degranulation of human neutrophils. Klempner, M.S., Styrt, B. J. Clin. Invest. (1983) [Pubmed]
  8. Small molecules that reactivate p53 in renal cell carcinoma reveal a NF-kappaB-dependent mechanism of p53 suppression in tumors. Gurova, K.V., Hill, J.E., Guo, C., Prokvolit, A., Burdelya, L.G., Samoylova, E., Khodyakova, A.V., Ganapathi, R., Ganapathi, M., Tararova, N.D., Bosykh, D., Lvovskiy, D., Webb, T.R., Stark, G.R., Gudkov, A.V. Proc. Natl. Acad. Sci. U.S.A. (2005) [Pubmed]
  9. Interactions of dicyclohexylcarbodiimide with myelin proteolipid. Lin, L.F., Lees, M.B. Proc. Natl. Acad. Sci. U.S.A. (1982) [Pubmed]
  10. Mutagen-nucleic acid intercalative binding: structure of a 9-aminoacridine: 5-iodocytidylyl(3'-5')guanosine crystalline complex. Sakore, T.D., Jain, S.C., Tsai, C.C., Sobell, H.M. Proc. Natl. Acad. Sci. U.S.A. (1977) [Pubmed]
  11. Topoisomerase II-mediated DNA damage produced by 4'-(9-acridinylamino)methanesulfon-m-anisidide and related acridines in L1210 cells and isolated nuclei: relation to cytotoxicity. Covey, J.M., Kohn, K.W., Kerrigan, D., Tilchen, E.J., Pommier, Y. Cancer Res. (1988) [Pubmed]
  12. Frameshift mutagenesis of lambda prophage by 9-aminoacridine, proflavin and ICR-191. Skopek, T.R., Hutchinson, F. Mol. Gen. Genet. (1984) [Pubmed]
  13. Glucose inhibition of mutagenesis by 9-aminoacridine in Salmonella typhimurium. Kopsidas, G., MacPhee, D.G. Mutat. Res. (1993) [Pubmed]
  14. Mutagenesis and anti-mutagenesis in Salmonella: influence of ethionine and caffeine on yields of mutations induced by 2-aminopurine and 9-aminoacridine. MacPhee, D.G., Nagel, B.A., Podger, D.M. Mutat. Res. (1983) [Pubmed]
  15. Anti-stress activity of Propionibacterium freudenreichii : identification of a reactivative protein. Vorobjeva, L., Leverrier, P., Zinchenko, A., Boyaval, P., Khodjaev, E., Varioukhina, S., Ponomareva, G., Gordeeva, E., Jan, G. Antonie Van Leeuwenhoek (2004) [Pubmed]
  16. Induction of deletion and insertion mutations by 9-aminoacridine. An in vitro model. Conrad, M., Topal, M.D. J. Biol. Chem. (1986) [Pubmed]
  17. Regulation of the transmembrane potential of isolated chromaffin granules by ATP, ATP analogs, and external pH. Pollard, H.B., Zinder, O., Hoffman, P.G., Nikodejevic, O. J. Biol. Chem. (1976) [Pubmed]
  18. Thermodynamics of the electrochemical proton gradient in bovine heart submitochondrial particles. Bashford, C.L., Thayer, W.S. J. Biol. Chem. (1977) [Pubmed]
  19. Antagonism of immunostimulatory CpG-oligodeoxynucleotides by quinacrine, chloroquine, and structurally related compounds. Macfarlane, D.E., Manzel, L. J. Immunol. (1998) [Pubmed]
  20. The delta pH-driven, ATP-independent protein translocation mechanism in the chloroplast thylakoid membrane. Kinetics and energetics. Brock, I.W., Mills, J.D., Robinson, D., Robinson, C. J. Biol. Chem. (1995) [Pubmed]
  21. Spectrophotometric measurements of transmembrane potential and pH gradients in chromaffin granules. Salama, G., Johnson, R.G., Scarpa, A. J. Gen. Physiol. (1980) [Pubmed]
  22. 9-Aminoacridine as a fluorescent probe of the electrical diffuse layer associated with the membranes of plant mitochondria. Møller, I.M., Chow, W.S., Palmer, J.M., Barber, J. Biochem. J. (1981) [Pubmed]
  23. Cytochrome b(6)f mutation specifically affects thermal dissipation of absorbed light energy in Arabidopsis. Munekage, Y., Takeda, S., Endo, T., Jahns, P., Hashimoto, T., Shikanai, T. Plant J. (2001) [Pubmed]
  24. Simultaneous measurement of deltapH and electron transport in chloroplast thylakoids by 9-aminoacridine fluorescence. Evron, Y., McCarty, R.E. Plant Physiol. (2000) [Pubmed]
  25. The regulation of exogenous NAD(P)H oxidation in spinach (Spinacia oleracea) leaf mitochondria by pH and cations. Edman, K., Ericson, I., Møller, I.M. Biochem. J. (1985) [Pubmed]
  26. Trapping of glutamate and glycine during open channel block of rat hippocampal neuron NMDA receptors by 9-aminoacridine. Benveniste, M., Mayer, M.L. J. Physiol. (Lond.) (1995) [Pubmed]
  27. Rapid sizing of short tandem repeat alleles using capillary array electrophoresis and energy-transfer fluorescent primers. Wang, Y., Ju, J., Carpenter, B.A., Atherton, J.M., Sensabaugh, G.F., Mathies, R.A. Anal. Chem. (1995) [Pubmed]
  28. Frameshift mutagenesis by 9-aminoacridine and ICR191 in Escherichia coli: effects of uvrB, recA and lexA mutations and of plasmid pKM101. Thomas, S.M., MacPhee, D.G. Mutat. Res. (1985) [Pubmed]
  29. A mutation in the DNA adenine methylase gene (dam) of Salmonella typhimurium decreases susceptibility to 9-aminoacridine-induced frameshift mutagenesis. Ritchie, L., Podger, D.M., Hall, R.M. Mutat. Res. (1988) [Pubmed]
  30. Frameshift mutagenesis in Salmonella typhimurium by reversible DNA intercalators: effect of a UVR B mutation. René, B., Auclair, C., Paoletti, C. Biochem. Biophys. Res. Commun. (1986) [Pubmed]
  31. Spontaneous and 9-aminoacridine-induced frameshift mutagenesis: second-site frameshift mutation within the N-terminal region of the lacI gene of Escherichia coli. Gordon, A.J., Halliday, J.A., Horsfall, M.J., Glickman, B.W. Mol. Gen. Genet. (1991) [Pubmed]
  32. Interaction of the antitumor drug 9-aminoacridine with guanidinobenzoatase studied by spectroscopic methods: a possible tumor marker probe based on the fluorescence exciplex emission. Murza, A., Sánchez-Cortés, S., García-Ramos, J.V., Guisan, J.M., Alfonso, C., Rivas, G. Biochemistry (2000) [Pubmed]
  33. Site exclusion and sequence specificity in binding of 9-aminoacridine to the deoxytetranucleotide dpApGpCpT. Young, P.R., Kallenbach, N.R. Proc. Natl. Acad. Sci. U.S.A. (1980) [Pubmed]
  34. The proteolipid subunit of the chloroplast adenosine triphosphatase complex. Reconstitution and demonstration of proton-conductive properties. Sigrist-Nelson, K., Azzi, A. J. Biol. Chem. (1980) [Pubmed]
  35. Energy-linked nicotinamide nucleotide transhydrogenase. Properties of proton-translocating mitochondrial transhydrogenase from beef heart purified by fast protein liquid chromatography. Persson, B., Enander, K., Tang, H.L., Rydström, J. J. Biol. Chem. (1984) [Pubmed]
  36. Interactions of intercalative and minor groove binding ligands with triplex poly(dA).[poly(dT)]2 and with duplex poly(dA).poly(dT) and poly[d(A-T)]2 studied by CD, LD, and normal absorption. Kim, H.K., Kim, J.M., Kim, S.K., Rodger, A., Nordén, B. Biochemistry (1996) [Pubmed]
  37. Metabolomic analysis of eukaryotic tissue and prokaryotes using negative mode MALDI time-of-flight mass spectrometry. Edwards, J.L., Kennedy, R.T. Anal. Chem. (2005) [Pubmed]
WikiGenes - Universities