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Gene Review

Apoa1  -  apolipoprotein A-I

Rattus norvegicus

Synonyms: Apo-AI, ApoA-I, Apolipoprotein A-I, Apolipoprotein A1
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Disease relevance of Apoa1


High impact information on Apoa1


Chemical compound and disease context of Apoa1


Biological context of Apoa1


Anatomical context of Apoa1


Associations of Apoa1 with chemical compounds


Physical interactions of Apoa1


Other interactions of Apoa1


Analytical, diagnostic and therapeutic context of Apoa1


  1. Monomethylethanolamine reduces plasma triacylglycerols and apolipoprotein B and increases apolipoprotein A-I rats without induction of fatty liver. Rusiñol, A.E., Lysak, P.S., Sigurdson, G.T., Vance, J.E. J. Lipid Res. (1996) [Pubmed]
  2. Catabolism of the apolipoproteins of HDL in control and nephrotic rats. Sparks, C.E., Tennenberg, S.D., Marsh, J.B. Biochim. Biophys. Acta (1981) [Pubmed]
  3. Synthetic high-density lipoproteins exert cardioprotective effects in myocardial ischemia/reperfusion injury. Rossoni, G., Gomaraschi, M., Berti, F., Sirtori, C.R., Franceschini, G., Calabresi, L. J. Pharmacol. Exp. Ther. (2004) [Pubmed]
  4. Rat liver transcript profiling in normal and disease states using a kinetic polymerase chain reaction assay. Kang, J.J., Kaysen, G.A., Jones, H., Holland, M.J. Methods (1997) [Pubmed]
  5. Ectopic beta-chain of ATP synthase is an apolipoprotein A-I receptor in hepatic HDL endocytosis. Martinez, L.O., Jacquet, S., Esteve, J.P., Rolland, C., Cabezón, E., Champagne, E., Pineau, T., Georgeaud, V., Walker, J.E., Tercé, F., Collet, X., Perret, B., Barbaras, R. Nature (2003) [Pubmed]
  6. Role of thyroid hormones in apolipoprotein A-I gene expression in rat liver. Strobl, W., Gorder, N.L., Lin-Lee, Y.C., Gotto, A.M., Patsch, W. J. Clin. Invest. (1990) [Pubmed]
  7. A role for apolipoprotein E, apolipoprotein A-I, and low density lipoprotein receptors in cholesterol transport during regeneration and remyelination of the rat sciatic nerve. Boyles, J.K., Zoellner, C.D., Anderson, L.J., Kosik, L.M., Pitas, R.E., Weisgraber, K.H., Hui, D.Y., Mahley, R.W., Gebicke-Haerter, P.J., Ignatius, M.J. J. Clin. Invest. (1989) [Pubmed]
  8. Intestinal apoproteins during fat absorption. Schonfeld, G., Bell, E., Alpers, D.H. J. Clin. Invest. (1978) [Pubmed]
  9. Effects of dehydroepiandrosterone on rat apolipoprotein AI gene expression in the human hepatoma cell line, HepG2. Deleon, M.J., Horani, M.H., Haas, M.J., Wong, N.C., Mooradian, A.D. Metab. Clin. Exp. (2002) [Pubmed]
  10. Induction of the apolipoprotein AI gene by fasting: a relationship with ketosis but not with ketone bodies. Haas, M.J., Reinacher, D., Pun, K., Wong, N.C., Mooradian, A.D. Metab. Clin. Exp. (2000) [Pubmed]
  11. Beneficial effects of apolipoprotein A-I on endotoxemia. Imai, T., Fujita, T., Yamazaki, Y. Surgery today. (2003) [Pubmed]
  12. Linkage, evolution, and expression of the rat apolipoprotein A-I, C-III, and A-IV genes. Haddad, I.A., Ordovas, J.M., Fitzpatrick, T., Karathanasis, S.K. J. Biol. Chem. (1986) [Pubmed]
  13. Apolipoprotein B messenger RNA editing in the rat liver. Modulation by fasting and refeeding a high carbohydrate diet. Baum, C.L., Teng, B.B., Davidson, N.O. J. Biol. Chem. (1990) [Pubmed]
  14. The effects of fat feeding on apolipoprotein AI secretion from rat small intestinal epithelium. Alpers, D.H., Lancaster, N., Schonfeld, G. Metab. Clin. Exp. (1982) [Pubmed]
  15. Identification of an enhancer-like element in the 5' flanking region of the rat apolipoprotein A-I gene. Chao, Y.S., Ding, X.H., Dai, P.H., Wu, T.J., Pan, T.C., Hao, Q.L., Yamin, T.T. Nucleic Acids Res. (1988) [Pubmed]
  16. Reduction of phosphatidylcholine hydroperoxide by apolipoprotein A-I: purification of the hydroperoxide-reducing proteins from human blood plasma. Mashima, R., Yamamoto, Y., Yoshimura, S. J. Lipid Res. (1998) [Pubmed]
  17. Apolipoprotein E is secreted by cultured lipocytes of the rat liver. Friedman, G., Liu, L.M., Friedman, S.L., Boyles, J.K. J. Lipid Res. (1991) [Pubmed]
  18. Cholestyramine and a fat-free diet lower apolipoprotein A-IV mRNA in jejunum and cholestyramine lowers apolipoprotein A-I mRNA in ileum of rats. Sonoyama, K., Nishikawa, H., Kiriyama, S., Niki, R. J. Nutr. (1994) [Pubmed]
  19. The primary translation product of rat intestinal apolipoprotein A-I mRNA is an unusual preproprotein. Gordon, J.I., Smith, D.P., Andy, R., Alpers, D.H., Schonfeld, G., Strauss, A.W. J. Biol. Chem. (1982) [Pubmed]
  20. Estrogen replacement during hypoalbuminemia may enhance atherosclerotic risk. Joles, J.A., Bijleveld, C., van Tol, A., Geelen, M.J., Koomans, H.A. J. Am. Soc. Nephrol. (1997) [Pubmed]
  21. Differential effects of continuous versus intermittent administration of growth hormone to hypophysectomized female rats on serum lipoproteins and their apoproteins. Oscarsson, J., Olofsson, S.O., Bondjers, G., Edén, S. Endocrinology (1989) [Pubmed]
  22. A linoleic acid enriched diet increases serum cholesterol esterification by lecithin:cholesterol acyltransferase in meal-fed rats. Romijn, D., Wiseman, S.A., Scheek, L.M., de Fouw, N.J., van Tol, A. Ann. Nutr. Metab. (1998) [Pubmed]
  23. Isolation and lipid-binding properties of rat apolipoprotein A-IV. Rifici, V.A., Eder, H.A., Swaney, J.B. Biochim. Biophys. Acta (1985) [Pubmed]
  24. Regulation of rat liver apolipoprotein A-I, apolipoprotein A-II and acyl-coenzyme A oxidase gene expression by fibrates and dietary fatty acids. Berthou, L., Saladin, R., Yaqoob, P., Branellec, D., Calder, P., Fruchart, J.C., Denèfle, P., Auwerx, J., Staels, B. Eur. J. Biochem. (1995) [Pubmed]
  25. Effects of caloric restriction and gender on rat serum paraoxonase 1 activity. Thomàs-Moyà, E., Gianotti, M., Lladó, I., Proenza, A.M. J. Nutr. Biochem. (2006) [Pubmed]
  26. Enhanced insulin secretion and cholesterol metabolism in congenic strains of the spontaneously diabetic (Type 2) Goto Kakizaki rat are controlled by independent genetic loci in rat chromosome 8. Wallis, R.H., Wallace, K.J., Collins, S.C., McAteer, M., Argoud, K., Bihoreau, M.T., Kaisaki, P.J., Gauguier, D. Diabetologia (2004) [Pubmed]
  27. Apolipoprotein A-I increases association of cytosolic cholesterol and caveolin-1 with microtubule cytoskeletons in rat astrocytes. Ito, J., Kheirollah, A., Nagayasu, Y., Lu, R., Kato, K., Yokoyama, S. J. Neurochem. (2006) [Pubmed]
  28. Apolipoprotein mRNA in liver and intestine of rats is affected by dietary beet fiber or cholestyramine. Sonoyama, K., Nishikawa, H., Kiriyama, S., Niki, R. J. Nutr. (1995) [Pubmed]
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