Gene Review:
Cdh5 - cadherin 5
Mus musculus
Synonyms:
7B4, 7B4/cadherin-5, AA408225, CD144, Cadherin-5, ...
- Cardiac ischemia activates vascular endothelial cadherin promoter in both preexisting vascular cells and bone marrow cells involved in neovascularization. Kogata, N., Arai, Y., Pearson, J.T., Hashimoto, K., Hidaka, K., Koyama, T., Somekawa, S., Nakaoka, Y., Ogawa, M., Adams, R.H., Okada, M., Mochizuki, N. Circ. Res. (2006)
- Junctional adhesion molecule-C regulates vascular endothelial permeability by modulating VE-cadherin-mediated cell-cell contacts. Orlova, V.V., Economopoulou, M., Lupu, F., Santoso, S., Chavakis, T. J. Exp. Med. (2006)
- Gene expression of VEGF and its receptors Flk-1/KDR and Flt-1 in cultured and transplanted rat islets. Vasir, B., Jonas, J.C., Steil, G.M., Hollister-Lock, J., Hasenkamp, W., Sharma, A., Bonner-Weir, S., Weir, G.C. Transplantation (2001)
- Effects of cadmium on E-cadherin and VE-cadherin in mouse lung. Pearson, C.A., Lamar, P.C., Prozialeck, W.C. Life Sci. (2003)
- Common quantitative trait loci for alcohol-related behaviors and CNS neurotensin measures: voluntary ethanol consumption. Gehle, V.M., Erwin, V.G. Alcohol. Clin. Exp. Res. (1998)
- Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation. Timmerman, L.A., Grego-Bessa, J., Raya, A., Bertrán, E., Pérez-Pomares, J.M., Díez, J., Aranda, S., Palomo, S., McCormick, F., Izpisúa-Belmonte, J.C., de la Pompa, J.L. Genes Dev. (2004)
- In vitro generation of lymphohematopoietic cells from endothelial cells purified from murine embryos. Nishikawa, S.I., Nishikawa, S., Kawamoto, H., Yoshida, H., Kizumoto, M., Kataoka, H., Katsura, Y. Immunity (1998)
- Histone deacetylase activity is essential for the expression of HoxA9 and for endothelial commitment of progenitor cells. Rössig, L., Urbich, C., Brühl, T., Dernbach, E., Heeschen, C., Chavakis, E., Sasaki, K., Aicher, D., Diehl, F., Seeger, F., Potente, M., Aicher, A., Zanetta, L., Dejana, E., Zeiher, A.M., Dimmeler, S. J. Exp. Med. (2005)
- Characterization of GATA-1(+) hemangioblastic cells in the mouse embryo. Yokomizo, T., Takahashi, S., Mochizuki, N., Kuroha, T., Ema, M., Wakamatsu, A., Shimizu, R., Ohneda, O., Osato, M., Okada, H., Komori, T., Ogawa, M., Nishikawa, S., Ito, Y., Yamamoto, M. EMBO J. (2007)
- N-cadherin acts upstream of VE-cadherin in controlling vascular morphogenesis. Luo, Y., Radice, G.L. J. Cell Biol. (2005)
- Senescence of visual function as studied by visually evoked cortical potentials. Adachi-Usami, E. Jpn. J. Ophthalmol. (1990)
- Anti-vascular endothelial cell antibodies in patients with IgA nephropathy: frequency and clinical significance. Yap, H.K., Sakai, R.S., Bahn, L., Rappaport, V., Woo, K.T., Ananthurman, V., Lim, C.H., Chiang, G.S., Jordan, S.C. Clin. Immunol. Immunopathol. (1988)
- VE-cadherin is not required for the formation of nascent blood vessels but acts to prevent their disassembly. Crosby, C.V., Fleming, P.A., Argraves, W.S., Corada, M., Zanetta, L., Dejana, E., Drake, C.J. Blood (2005)
- Caveolin-1-deficient mice have increased tumor microvascular permeability, angiogenesis, and growth. Lin, M.I., Yu, J., Murata, T., Sessa, W.C. Cancer Res. (2007)
- Distinct Pattern of Allelic Loss and Inactivation of Cadherin 1 and 5 Genes in Mammary Carcinomas Arising in p53(+/-) Mice. Umesako, S., Iiga, S., Takahashi, M., Imura, K., Mori, N., Hong, D.P., Song, C.W., Niwa, O., Okumoto, M. J. Radiat. Res. (2007)
- Molecular cloning and expression of murine vascular endothelial-cadherin in early stage development of cardiovascular system. Breier, G., Breviario, F., Caveda, L., Berthier, R., Schnürch, H., Gotsch, U., Vestweber, D., Risau, W., Dejana, E. Blood (1996)
- VE-cadherin increases the half-life of VEGF receptor 2. Calera, M.R., Venkatakrishnan, A., Kazlauskas, A. Exp. Cell Res. (2004)
- Phenotype and hematopoietic potential of side population cells throughout embryonic development. Nadin, B.M., Goodell, M.A., Hirschi, K.K. Blood (2003)
- Platelet-activating factor increases VE-cadherin tyrosine phosphorylation in mouse endothelial cells and its association with the PtdIns3'-kinase. Hudry-Clergeon, H., Stengel, D., Ninio, E., Vilgrain, I. FASEB J. (2005)
- Vascular endothelial cell-specific phosphotyrosine phosphatase (VE-PTP) activity is required for blood vessel development. Bäumer, S., Keller, L., Holtmann, A., Funke, R., August, B., Gamp, A., Wolburg, H., Wolburg-Buchholz, K., Deutsch, U., Vestweber, D. Blood (2006)
- Self-assembly of the vascular endothelial cadherin ectodomain in a Ca2+-dependent hexameric structure. Legrand, P., Bibert, S., Jaquinod, M., Ebel, C., Hewat, E., Vincent, F., Vanbelle, C., Concord, E., Vernet, T., Gulino, D. J. Biol. Chem. (2001)
- Establishment of an immortalized human-liver endothelial cell line with SV40T and hTERT. Matsumura, T., Takesue, M., Westerman, K.A., Okitsu, T., Sakaguchi, M., Fukazawa, T., Totsugawa, T., Noguchi, H., Yamamoto, S., Stolz, D.B., Tanaka, N., Leboulch, P., Kobayashi, N. Transplantation (2004)
- Phosphorylation of vascular endothelial cadherin controls lymphocyte emigration. Turowski, P., Martinelli, R., Crawford, R., Wateridge, D., Papageorgiou, A.P., Lampugnani, M.G., Gamp, A.C., Vestweber, D., Adamson, P., Dejana, E., Greenwood, J. J. Cell. Sci. (2008)
- ETS1 lowers capillary endothelial cell density at confluence and induces the expression of VE-cadherin. Lelièvre, E., Mattot, V., Huber, P., Vandenbunder, B., Soncin, F. Oncogene (2000)
- Role of adhesion and contraction in Rac 1-regulated endothelial barrier function in vivo and in vitro. Waschke, J., Drenckhahn, D., Adamson, R.H., Curry, F.E. Am. J. Physiol. Heart Circ. Physiol. (2004)
- Modulation of VEGFR-2-mediated endothelial-cell activity by VEGF-C/VEGFR-3. Matsumura, K., Hirashima, M., Ogawa, M., Kubo, H., Hisatsune, H., Kondo, N., Nishikawa, S., Chiba, T., Nishikawa, S. Blood (2003)
- Gas1 is induced by VE-cadherin and vascular endothelial growth factor and inhibits endothelial cell apoptosis. Spagnuolo, R., Corada, M., Orsenigo, F., Zanetta, L., Deuschle, U., Sandy, P., Schneider, C., Drake, C.J., Breviario, F., Dejana, E. Blood (2004)
- Genomic structure and chromosomal mapping of the mouse VE-cadherin gene (Cdh5). Huber, P., Dalmon, J., Engiles, J., Breviario, F., Gory, S., Siracusa, L.D., Buchberg, A.M., Dejana, E. Genomics (1996)
- Isolation and Characterization of A Novel Mouse Lymphatic Endothelial Cell Line: SV-LEC. Ando, T., Jordan, P., Joh, T., Wang, Y., Jennings, M.H., Houghton, J., Alexander, J.S. Lymphatic research and biology. (2005)
- Targeted null-mutation in the vascular endothelial-cadherin gene impairs the organization of vascular-like structures in embryoid bodies. Vittet, D., Buchou, T., Schweitzer, A., Dejana, E., Huber, P. Proc. Natl. Acad. Sci. U.S.A. (1997)
- A general strategy for isolation of endothelial cells from murine tissues. Characterization of two endothelial cell lines from the murine lung and subcutaneous sponge implants. Dong, Q.G., Bernasconi, S., Lostaglio, S., De Calmanovici, R.W., Martin-Padura, I., Breviario, F., Garlanda, C., Ramponi, S., Mantovani, A., Vecchi, A. Arterioscler. Thromb. Vasc. Biol. (1997)
- Cellular expression of integrin-beta 1 is of critical importance for inducing therapeutic angiogenesis by cell implantation. Li, T.S., Ito, H., Hayashi, M., Furutani, A., Matsuzaki, M., Hamano, K. Cardiovasc. Res. (2005)
- Requirement of Rac activity for maintenance of capillary endothelial barrier properties. Waschke, J., Baumgartner, W., Adamson, R.H., Zeng, M., Aktories, K., Barth, H., Wilde, C., Curry, F.E., Drenckhahn, D. Am. J. Physiol. Heart Circ. Physiol. (2004)