Gene Review:
Tgm2 - transglutaminase 2, C polypeptide
Mus musculus
Synonyms:
G[a]h, Protein-glutamine gamma-glutamyltransferase 2, TG C, TG(C), TG2, ...
Szondy,
Sarang,
Molnar,
Nemeth,
Piacentini,
Mastroberardino,
Falasca,
Aeschlimann,
Kovacs,
Kiss,
Szegezdi,
Lakos,
Rajnavolgyi,
Birckbichler,
Melino,
Fesus,
- Tissue transglutaminase contributes to disease progression in the R6/2 Huntington's disease mouse model via aggregate-independent mechanisms. Bailey, C.D., Johnson, G.V. J. Neurochem. (2005)
- Tetanus toxin potently stimulates tissue transglutaminase. A possible mechanism of neurotoxicity. Facchiano, F., Luini, A. J. Biol. Chem. (1992)
- Suppression of macrophage cytostatic activation by serum retinoids: a possible role for transglutaminase. Mehta, K., Claringbold, P., Lopez-Berestein, G. J. Immunol. (1987)
- Tissue transglutaminase 2 inhibition promotes cell death and chemosensitivity in glioblastomas. Yuan, L., Choi, K., Khosla, C., Zheng, X., Higashikubo, R., Chicoine, M.R., Rich, K.M. Mol. Cancer Ther. (2005)
- Reversal of liver fibrosis in aryl hydrocarbon receptor null mice by dietary vitamin A depletion. Andreola, F., Calvisi, D.F., Elizondo, G., Jakowlew, S.B., Mariano, J., Gonzalez, F.J., De Luca, L.M. Hepatology (2004)
- The protective effects of cystamine in the R6/2 Huntington's disease mouse involve mechanisms other than the inhibition of tissue transglutaminase. Bailey, C.D., Johnson, G.V. Neurobiol. Aging (2006)
- A retinoic acid receptor antagonist suppresses brain retinoic acid receptor overexpression and reverses a working memory deficit induced by chronic ethanol consumption in mice. Alfos, S., Boucheron, C., Pallet, V., Higueret, D., Enderlin, V., Béracochéa, D., Jaffard, R., Higueret, P. Alcohol. Clin. Exp. Res. (2001)
- Tissue transglutaminase autoantibody enzyme-linked immunosorbent assay in detecting celiac disease. Sulkanen, S., Halttunen, T., Laurila, K., Kolho, K.L., Korponay-Szabó, I.R., Sarnesto, A., Savilahti, E., Collin, P., Mäki, M. Gastroenterology (1998)
- Expression of tissue transglutaminase in Balb-C 3T3 fibroblasts: effects on cellular morphology and adhesion. Gentile, V., Thomazy, V., Piacentini, M., Fesus, L., Davies, P.J. J. Cell Biol. (1992)
- Transglutaminase 2-/- mice reveal a phagocytosis-associated crosstalk between macrophages and apoptotic cells. Szondy, Z., Sarang, Z., Molnar, P., Nemeth, T., Piacentini, M., Mastroberardino, P.G., Falasca, L., Aeschlimann, D., Kovacs, J., Kiss, I., Szegezdi, E., Lakos, G., Rajnavolgyi, E., Birckbichler, P.J., Melino, G., Fesus, L. Proc. Natl. Acad. Sci. U.S.A. (2003)
- Fetal mouse selenophosphate synthetase 2 (SPS2): characterization of the cysteine mutant form overproduced in a baculovirus-insect cell system. Kim, I.Y., Guimarães, M.J., Zlotnik, A., Bazan, J.F., Stadtman, T.C. Proc. Natl. Acad. Sci. U.S.A. (1997)
- The promoter of the mouse tissue transglutaminase gene directs tissue-specific, retinoid-regulated and apoptosis-linked expression. Nagy, L., Thomázy, V.A., Saydak, M.M., Stein, J.P., Davies, P.J. Cell Death Differ. (1997)
- Identification of a novel recognition sequence for fibronectin within the NH2-terminal beta-sandwich domain of tissue transglutaminase. Hang, J., Zemskov, E.A., Lorand, L., Belkin, A.M. J. Biol. Chem. (2005)
- Opposing roles of Ras/Raf oncogenes and the MEK1/ERK signaling module in regulation of expression and adhesive function of surface transglutaminase. Akimov, S.S., Belkin, A.M. J. Biol. Chem. (2003)
- Developmental regulation of tissue transglutaminase in the mouse forebrain. Bailey, C.D., Johnson, G.V. J. Neurochem. (2004)
- Regulation of the dual function tissue transglutaminase/Galpha(h) during murine neuromuscular development: gene and enzyme isoform expression. Citron, B.A., Gregory, E.J., Steigerwalt, D.S., Qin, F., Festoff, B.W. Neurochem. Int. (2000)
- Targeted inactivation of Gh/tissue transglutaminase II. Nanda, N., Iismaa, S.E., Owens, W.A., Husain, A., Mackay, F., Graham, R.M. J. Biol. Chem. (2001)
- Tissue transglutaminase (TG2) acting as G protein protects hepatocytes against Fas-mediated cell death in mice. Sarang, Z., Molnár, P., Németh, T., Gomba, S., Kardon, T., Melino, G., Cotecchia, S., Fésüs, L., Szondy, Z. Hepatology (2005)
- Gene disruption of tissue transglutaminase. De Laurenzi, V., Melino, G. Mol. Cell. Biol. (2001)
- Transglutaminase and clusterin induction during normal and abnormal limb development in the mouse. Adel Moallem, S., Hales, B.F. Biol. Reprod. (1996)
- Cell surface localization of tissue transglutaminase is dependent on a fibronectin-binding site in its N-terminal beta-sandwich domain. Gaudry, C.A., Verderio, E., Aeschlimann, D., Cox, A., Smith, C., Griffin, M. J. Biol. Chem. (1999)
- Lack of induction of tissue transglutaminase but activation of the preexisting enzyme in c-Myc-induced apoptosis of CHO cells. Balajthy, Z., Kedei, N., Nagy, L., Davies, P.J., Fésüs, L. Biochem. Biophys. Res. Commun. (1997)
- Tissue transglutaminase triggers oligomerization and activation of dual leucine zipper-bearing kinase in calphostin C-treated cells to facilitate apoptosis. Robitaille, K., Daviau, A., Tucholski, J., Johnson, G.V., Rancourt, C., Blouin, R. Cell Death Differ. (2004)
- Cross-linking of cellular proteins by tissue transglutaminase during necrotic cell death: a mechanism for maintaining tissue integrity. Nicholas, B., Smethurst, P., Verderio, E., Jones, R., Griffin, M. Biochem. J. (2003)
- Arachidonic acid activates tissue transglutaminase and stress fiber formation via intracellular reactive oxygen species. Yi, S.J., Choi, H.J., Yoo, J.O., Yuk, J.S., Jung, H.I., Lee, S.H., Han, J.A., Kim, Y.M., Ha, K.S. Biochem. Biophys. Res. Commun. (2004)
- Differential expression of tissue transglutaminase protein in mouse ovarian follicle. Lee, C.J., Do, B.R., Lee, J.M., Song, K.W., Kang, J.S., Park, M.H. In Vivo (2003)