Gene Review:
Phospho1 - phosphatase, orphan 1
Mus musculus
Synonyms:
D11Moh36, Phosphoethanolamine/phosphocholine phosphatase, Phospo1
- Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha. Novoa, I., Zeng, H., Harding, H.P., Ron, D. J. Cell Biol. (2001)
- The S100A7-c-Jun activation domain binding protein 1 pathway enhances prosurvival pathways in breast cancer. Emberley, E.D., Niu, Y., Curtis, L., Troup, S., Mandal, S.K., Myers, J.N., Gibson, S.B., Murphy, L.C., Watson, P.H. Cancer Res. (2005)
- Caveolin-3 knock-out mice develop a progressive cardiomyopathy and show hyperactivation of the p42/44 MAPK cascade. Woodman, S.E., Park, D.S., Cohen, A.W., Cheung, M.W., Chandra, M., Shirani, J., Tang, B., Jelicks, L.A., Kitsis, R.N., Christ, G.J., Factor, S.M., Tanowitz, H.B., Lisanti, M.P. J. Biol. Chem. (2002)
- Microglia recognize double-stranded RNA via TLR3. Town, T., Jeng, D., Alexopoulou, L., Tan, J., Flavell, R.A. J. Immunol. (2006)
- Biochemical correlates of mTOR inhibition by the rapamycin ester CCI-779 and tumor growth inhibition. Dudkin, L., Dilling, M.B., Cheshire, P.J., Harwood, F.C., Hollingshead, M., Arbuck, S.G., Travis, R., Sausville, E.A., Houghton, P.J. Clin. Cancer Res. (2001)
- Cyclic AMP response element-binding protein is required for normal maternal nurturing behavior. Jin, S.H., Blendy, J.A., Thomas, S.A. Neuroscience (2005)
- Partial T cell signaling: altered phospho-zeta and lack of zap70 recruitment in APL-induced T cell anergy. Sloan-Lancaster, J., Shaw, A.S., Rothbard, J.B., Allen, P.M. Cell (1994)
- High- and low-potency ligands with similar affinities for the TCR: the importance of kinetics in TCR signaling. Kersh, G.J., Kersh, E.N., Fremont, D.H., Allen, P.M. Immunity (1998)
- Phospho-caveolin-1 mediates integrin-regulated membrane domain internalization. del Pozo, M.A., Balasubramanian, N., Alderson, N.B., Kiosses, W.B., Grande-García, A., Anderson, R.G., Schwartz, M.A. Nat. Cell Biol. (2005)
- Cerebellar long-term depression requires PKC-regulated interactions between GluR2/3 and PDZ domain-containing proteins. Xia, J., Chung, H.J., Wihler, C., Huganir, R.L., Linden, D.J. Neuron (2000)
- A phospho-switch controls the dynamic association of synapsins with synaptic vesicles. Hosaka, M., Hammer, R.E., Südhof, T.C. Neuron (1999)
- Folate deprivation induces neurodegeneration: roles of oxidative stress and increased homocysteine. Ho, P.I., Ashline, D., Dhitavat, S., Ortiz, D., Collins, S.C., Shea, T.B., Rogers, E. Neurobiol. Dis. (2003)
- Ethanol-mediated inhibition of mitogen-activated protein kinase phosphorylation in mouse brain. Kalluri, H.S., Ticku, M.K. Eur. J. Pharmacol. (2002)
- In situ transduction of stromal cells and thymocytes upon intrathymic injection of lentiviral vectors. Marodon, G., Klatzmann, D. BMC Immunol. (2004)
- The dietary isothiocyanate sulforaphane targets pathways of apoptosis, cell cycle arrest, and oxidative stress in human pancreatic cancer cells and inhibits tumor growth in severe combined immunodeficient mice. Pham, N.A., Jacobberger, J.W., Schimmer, A.D., Cao, P., Gronda, M., Hedley, D.W. Mol. Cancer Ther. (2004)
- ATM promotes apoptosis and suppresses tumorigenesis in response to Myc. Pusapati, R.V., Rounbehler, R.J., Hong, S., Powers, J.T., Yan, M., Kiguchi, K., McArthur, M.J., Wong, P.K., Johnson, D.G. Proc. Natl. Acad. Sci. U.S.A. (2006)
- B-Raf acts via the ROCKII/LIMK/cofilin pathway to maintain actin stress fibers in fibroblasts. Pritchard, C.A., Hayes, L., Wojnowski, L., Zimmer, A., Marais, R.M., Norman, J.C. Mol. Cell. Biol. (2004)
- The duration of nuclear extracellular signal-regulated kinase 1 and 2 signaling during cell cycle reentry distinguishes proliferation from apoptosis in response to asbestos. Yuan, Z., Taatjes, D.J., Mossman, B.T., Heintz, N.H. Cancer Res. (2004)
- Characterization of the mouse bile salt export pump overexpressed in the baculovirus system. Noe, J., Hagenbuch, B., Meier, P.J., St-Pierre, M.V. Hepatology (2001)
- A reinvestigation of the multisite phosphorylation of the transcription factor c-Jun. Morton, S., Davis, R.J., McLaren, A., Cohen, P. EMBO J. (2003)
- S-acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes. Kabouridis, P.S., Magee, A.I., Ley, S.C. EMBO J. (1997)
- Distinct gene expression profiles and reduced JNK signaling in retinitis pigmentosa caused by RP1 mutations. Liu, J., Huang, Q., Higdon, J., Liu, W., Xie, T., Yamashita, T., Cheon, K., Cheng, C., Zuo, J. Hum. Mol. Genet. (2005)
- Phosphorylation of tyrosine 291 enhances the ability of WASp to stimulate actin polymerization and filopodium formation. Wiskott-Aldrich Syndrome protein. Cory, G.O., Garg, R., Cramer, R., Ridley, A.J. J. Biol. Chem. (2002)
- RhoE function is regulated by ROCK I-mediated phosphorylation. Riento, K., Totty, N., Villalonga, P., Garg, R., Guasch, R., Ridley, A.J. EMBO J. (2005)
- ERK phosphorylation potentiates Elk-1-mediated ternary complex formation and transactivation. Gille, H., Kortenjann, M., Thomae, O., Moomaw, C., Slaughter, C., Cobb, M.H., Shaw, P.E. EMBO J. (1995)
- Insulin-stimulated microtubule-associated protein kinase is phosphorylated on tyrosine and threonine in vivo. Ray, L.B., Sturgill, T.W. Proc. Natl. Acad. Sci. U.S.A. (1988)
- S6 kinase in quiescent Swiss mouse 3T3 cells is activated by phosphorylation in response to serum treatment. Ballou, L.M., Siegmann, M., Thomas, G. Proc. Natl. Acad. Sci. U.S.A. (1988)
- Membranes from T and B lymphocytes have different patterns of tyrosine phosphorylation. Earp, H.S., Austin, K.S., Buessow, S.C., Dy, R., Gillespie, G.Y. Proc. Natl. Acad. Sci. U.S.A. (1984)
- Activation-induced bi-dentate interaction of SHIP and Shc in B lymphocytes. Pradhan, M., Coggeshall, K.M. J. Cell. Biochem. (1997)
- Light- and clock-dependent regulation of ribosomal S6 kinase activity in the suprachiasmatic nucleus. Butcher, G.Q., Lee, B., Hsieh, F., Obrietan, K. Eur. J. Neurosci. (2004)
- MEK inhibition and phosphorylation of serine 4 on B23 are two coincident events in mitosis. Hayne, C., Xiang, X., Luo, Z. Biochem. Biophys. Res. Commun. (2004)
- A definitive role of Shp-2 tyrosine phosphatase in mediating embryonic stem cell differentiation and hematopoiesis. Chan, R.J., Johnson, S.A., Li, Y., Yoder, M.C., Feng, G.S. Blood (2003)
- Merlin phosphorylation by p21-activated kinase 2 and effects of phosphorylation on merlin localization. Kissil, J.L., Johnson, K.C., Eckman, M.S., Jacks, T. J. Biol. Chem. (2002)
- The ERK-1/2 signaling pathway is involved in the stimulation of branching morphogenesis of fetal mouse submandibular glands by EGF. Kashimata, M., Sayeed, S., Ka, A., Onetti-Muda, A., Sakagami, H., Faraggiana, T., Gresik, E.W. Dev. Biol. (2000)
- Overexpression of Smad2 in Tgf-beta3-null mutant mice rescues cleft palate. Cui, X.M., Shiomi, N., Chen, J., Saito, T., Yamamoto, T., Ito, Y., Bringas, P., Chai, Y., Shuler, C.F. Dev. Biol. (2005)
- Polycyclic aromatic hydrocarbons induce both apoptotic and anti-apoptotic signals in Hepa1c1c7 cells. Solhaug, A., Refsnes, M., Låg, M., Schwarze, P.E., Husøy, T., Holme, J.A. Carcinogenesis (2004)
- Activation of B-Raf kinase requires phosphorylation of the conserved residues Thr598 and Ser601. Zhang, B.H., Guan, K.L. EMBO J. (2000)
- Bombesin, vasopressin, and endothelin rapidly stimulate tyrosine phosphorylation in intact Swiss 3T3 cells. Zachary, I., Gil, J., Lehmann, W., Sinnett-Smith, J., Rozengurt, E. Proc. Natl. Acad. Sci. U.S.A. (1991)
- Cell cycle-dependent phosphorylation of mammalian protein phosphatase 1 by cdc2 kinase. Kwon, Y.G., Lee, S.Y., Choi, Y., Greengard, P., Nairn, A.C. Proc. Natl. Acad. Sci. U.S.A. (1997)
- DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein: regional, tissue, and phylogenetic distribution. Hemmings, H.C., Greengard, P. J. Neurosci. (1986)