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Gene Review

Cntfr  -  ciliary neurotrophic factor receptor

Rattus norvegicus

Synonyms: CNTF receptor subunit alpha, CNTFR-alpha, Ciliary neurotrophic factor receptor subunit alpha
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Analytical, diagnostic and therapeutic context of Cntfr


  1. Expression of ciliary neurotrophic factor (CNTF), CNTF receptor alpha (CNTFR-alpha) following experimental intracerebral hemorrhage in rats. Yokota, H., Yoshikawa, M., Hirabayashi, H., Nakase, H., Uranishi, R., Nishimura, F., Sugie, Y., Ishizaka, S., Sakaki, T. Neurosci. Lett. (2005) [Pubmed]
  2. Upregulation of ciliary neurotrophic factor (CNTF) and CNTF receptor alpha in rat kidney with ischemia-reperfusion injury. Yang, C.W., Lim, S.W., Han, K.W., Ahn, H.J., Park, J.H., Kim, Y.H., Kirsh, M., Cha, J.H., Park, J.H., Kim, Y.S., Kim, J., Bang, B.K. J. Am. Soc. Nephrol. (2001) [Pubmed]
  3. Differential regulation of ciliary neurotrophic factor (CNTF) and CNTF receptor alpha (CNTFR alpha) expression following focal cerebral ischemia. Lin, T.N., Wang, P.Y., Chi, S.I., Kuo, J.S. Brain Res. Mol. Brain Res. (1998) [Pubmed]
  4. The alpha component of the CNTF receptor is required for signaling and defines potential CNTF targets in the adult and during development. Ip, N.Y., McClain, J., Barrezueta, N.X., Aldrich, T.H., Pan, L., Li, Y., Wiegand, S.J., Friedman, B., Davis, S., Yancopoulos, G.D. Neuron (1993) [Pubmed]
  5. Ciliary neurotrophic factor prevents retrograde neuronal death in the adult central nervous system. Clatterbuck, R.E., Price, D.L., Koliatsos, V.E. Proc. Natl. Acad. Sci. U.S.A. (1993) [Pubmed]
  6. Immunohistochemical localization of ciliary neurotrophic factor receptor alpha expression in the rat nervous system. MacLennan, A.J., Vinson, E.N., Marks, L., McLaurin, D.L., Pfeifer, M., Lee, N. J. Neurosci. (1996) [Pubmed]
  7. Ciliary neurotrophic factor protects retinal ganglion cells from axotomy-induced apoptosis via modulation of retinal glia in vivo. van Adel, B.A., Arnold, J.M., Phipps, J., Doering, L.C., Ball, A.K. J. Neurobiol. (2005) [Pubmed]
  8. CNTF induces raphe neuronal precursors to switch from a serotonergic to a cholinergic phenotype in vitro. Rudge, J.S., Eaton, M.J., Mather, P., Lindsay, R.M., Whittemore, S.R. Mol. Cell. Neurosci. (1996) [Pubmed]
  9. In vivo localization and characterization of functional ciliary neurotrophic factor receptors which utilize JAK-STAT signaling. MacLennan, A.J., Neitzel, K.L., Devlin, B.K., Garcia, J., Hauptman, G.A., Gloaguen, I., Di Marco, A., Laufer, R., Lee, N. Neuroscience (2000) [Pubmed]
  10. Expression of ciliary neurotrophic factor receptor-alpha messenger RNA in neonatal and adult rat brain: an in situ hybridization study. Lee, M.Y., Hofmann, H.D., Kirsch, M. Neuroscience (1997) [Pubmed]
  11. Promotion of the development of enteric neurons and glia by neuropoietic cytokines: interactions with neurotrophin-3. Chalazonitis, A., Rothman, T.P., Chen, J., Vinson, E.N., MacLennan, A.J., Gershon, M.D. Dev. Biol. (1998) [Pubmed]
  12. Differential regulation of ciliary neurotrophic factor (CNTF) and CNTF receptor alpha expression in astrocytes and neurons of the fascia dentata after entorhinal cortex lesion. Lee, M.Y., Deller, T., Kirsch, M., Frotscher, M., Hofmann, H.D. J. Neurosci. (1997) [Pubmed]
  13. Differential expression of ciliary neurotrophic factor receptor in skeletal muscle of chick and rat after nerve injury. Ip, F.C., Fu, A.K., Tsim, K.W., Ip, N.Y. J. Neurochem. (1996) [Pubmed]
  14. Lesion-induced changes in the expression of ciliary neurotrophic factor and its receptor in rat optic nerve. Kirsch, M., Schneider, T., Lee, M.Y., Hofmann, H.D. Glia (1998) [Pubmed]
  15. Expression and androgen regulation of the ciliary neurotrophic factor receptor (CNTFRalpha) in muscles and spinal cord. Xu, J., Forger, N.G. J. Neurobiol. (1998) [Pubmed]
  16. Motoneuron survival and expression of neuropeptides and neurotrophic factor receptors following axotomy in adult and ageing rats. Johnson, I.P., Duberley, R.M. Neuroscience (1998) [Pubmed]
  17. Increased expression of the alpha subunit of the ciliary neurotrophic factor (CNTF) receptor by rat racial motoneurons after neonatal axotomy and CNTF treatment. Duberley, R.M., Johnson, I.P. Neurosci. Lett. (1996) [Pubmed]
  18. Expression of ciliary neurotrophic factor receptor mRNA and protein in the early postnatal and adult rat nervous system. Kirsch, M., Hofmann, H.D. Neurosci. Lett. (1994) [Pubmed]
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