Gene Review:
IFNA2 - interferon, alpha 2
Homo sapiens
Synonyms:
IFN-alpha-2, IFN-alphaA, IFNA, IFNA2A, IFNA2B, ...
- Correlation between interferon (IFN) alpha resistance and deletion of the IFN alpha/beta genes in acute leukemia cell lines suggests selection against the IFN system. Colamonici, O.R., Domanski, P., Platanias, L.C., Diaz, M.O. Blood (1992)
- Human interferon alpha A or alpha D and trifluridine treatment for herpetic keratitis in rabbits. Trousdale, M.D., Nesburn, A.B. Invest. Ophthalmol. Vis. Sci. (1984)
- Diversity in inhibitory effects of IFN-gamma and IFN-alpha A on the induced DNA synthesis of a hairy cell leukemia B lymphocyte clone reflects the nature of the activating ligand. Mongini, P., Seremetis, S., Blessinger, C., Rudich, S., Winchester, R., Brunda, M. Blood (1988)
- Inhibition of intravascular mouse melanoma dissemination by recombinant human interferon alpha A/D. Yokoyama, T., Yoshie, O., Aso, H., Ebina, T., Ishida, N. Jpn. J. Cancer Res. (1986)
- A rare form of narcolepsy (HLA-DR2-) shows possible association with (functionally relevant) alpha-interferon gene polymorphisms. Wieczorek, S., Dahmen, N., Kasten, M., Epplen, J.T., Gencik, M. Psychiatr. Genet. (2004)
- Hematologic remission and cytogenetic improvement induced by recombinant human interferon alpha A in chronic myelogenous leukemia. Talpaz, M., Kantarjian, H.M., McCredie, K., Trujillo, J.M., Keating, M.J., Gutterman, J.U. N. Engl. J. Med. (1986)
- Assignment of a locus for familial melanoma, MLM, to chromosome 9p13-p22. Cannon-Albright, L.A., Goldgar, D.E., Meyer, L.J., Lewis, C.M., Anderson, D.E., Fountain, J.W., Hegi, M.E., Wiseman, R.W., Petty, E.M., Bale, A.E. Science (1992)
- Allele-specific loss in chromosome 9p loci in preneoplastic lesions accompanying non-small-cell lung cancers. Kishimoto, Y., Sugio, K., Hung, J.Y., Virmani, A.K., McIntire, D.D., Minna, J.D., Gazdar, A.F. J. Natl. Cancer Inst. (1995)
- Prospects for the prevention and therapy of infections with the human immunodeficiency virus. Vogt, M., Hirsch, M.S. Rev. Infect. Dis. (1986)
- Inhibition of theophylline metabolism by interferon. Williams, S.J., Baird-Lambert, J.A., Farrell, G.C. Lancet (1987)
- Three-drug synergistic inhibition of HIV-1 replication in vitro by zidovudine, recombinant soluble CD4, and recombinant interferon-alpha A. Johnson, V.A., Barlow, M.A., Merrill, D.P., Chou, T.C., Hirsch, M.S. J. Infect. Dis. (1990)
- Synergistic interaction of 2',3'-dideoxycytidine and recombinant interferon-alpha-A on replication of human immunodeficiency virus type 1. Vogt, M.W., Durno, A.G., Chou, T.C., Coleman, L.A., Paradis, T.J., Schooley, R.T., Kaplan, J.C., Hirsch, M.S. J. Infect. Dis. (1988)
- Two-drug combinations of zidovudine, didanosine, and recombinant interferon-alpha A inhibit replication of zidovudine-resistant human immunodeficiency virus type 1 synergistically in vitro. Johnson, V.A., Merrill, D.P., Videler, J.A., Chou, T.C., Byington, R.E., Eron, J.J., D'Aquila, R.T., Hirsch, M.S. J. Infect. Dis. (1991)
- Polymorphism in the interferon-alpha gene family. Golovleva, I., Kandefer-Szerszen, M., Beckman, L., Lundgren, E. Am. J. Hum. Genet. (1996)
- DNA sequence of a major human leukocyte interferon gene. Lawn, R.M., Gross, M., Houck, C.M., Franke, A.E., Gray, P.V., Goeddel, D.V. Proc. Natl. Acad. Sci. U.S.A. (1981)
- Effect of recombinant human interferon-alpha A/D on in vivo murine tumor cell growth. Uno, K., Shimizu, S., Inaba, K., Kitaura, M., Nakahira, K., Kato, T., Yamaguchi, Y., Muramatsu, S. Cancer Res. (1988)
- Creation of phosphorylation sites in proteins: construction of a phosphorylatable human interferon alpha. Li, B.L., Langer, J.A., Schwartz, B., Pestka, S. Proc. Natl. Acad. Sci. U.S.A. (1989)
- Transcription of interferon-alpha 2 alleles from virus-induced human leucocytes and lymphoblastoid cells of African origin. Linge, C., Gewert, D., Ellis, J., Tucker, D., Allen, G., Crowe, J.S. Biochim. Biophys. Acta (1995)
- Characterization of the interferon regulatory factor-7 and its potential role in the transcription activation of interferon A genes. Au, W.C., Moore, P.A., LaFleur, D.W., Tombal, B., Pitha, P.M. J. Biol. Chem. (1998)
- Potentiation of antitumor activity of macrophages by recombinant interferon alpha A/D contained in gelatin microspheres. Tabata, Y., Uno, K., Ikada, Y., Muramatsu, S. Jpn. J. Cancer Res. (1988)
- The effects of interferon-alpha2a on concentrations of immunoglobulins, complement and lymphocytes in patients with multiple sclerosis. Ulvestad, E., Aarseth, J.H., Vedeler, C., Nyland, H., Myhr, K.M. Scand. J. Immunol. (2004)
- Analysis of functional domains of interferon regulatory factor 7 and its association with IRF-3. Au, W.C., Yeow, W.S., Pitha, P.M. Virology (2001)
- Effect of the combination of interferon-alpha and stavudine on Friend virus infections in (B10.A x A.By)F1 mice. Sidwell, R.W., Warren, R.P., Okleberry, K., Burger, R.A., Morrey, J.D. J. Infect. Dis. (1995)
- Localization of 2',5'-oligoadenylate synthetase and the enhancement of its activity with recombinant interferon-alpha A/D in the mouse brain. Asada-Kubota, M., Ueda, T., Nakashima, T., Kobayashi, M., Shimada, M., Takeda, K., Hamada, K., Maekawa, S., Sokawa, Y. Anat. Embryol. (1997)
- Binding of 125I-labeled human interferon to cell lines with low sensitivity to interferon. Fuse, A., Ashino-Fuse, H., Kuwata, T. Gann = Gan. (1984)
- Interferon-alpha prevents endotoxin-induced mortality in mice. Tzung, S.P., Mahl, T.C., Lance, P., Andersen, V., Cohen, S.A. Eur. J. Immunol. (1992)
- Novel variants of human IFN-alpha detected in tumor cell lines and biopsy specimens. Golovleva, I., Biasotto, M., Verpy, E., Roos, G., Meo, T., Tosi, M., Lundgren, E. J. Interferon Cytokine Res. (1997)
- Bacterial synthesis of a novel human leukocyte interferon. Yelverton, E., Leung, D., Weck, P., Gray, P.W., Goeddel, D.V. Nucleic Acids Res. (1981)
- A functional protein kinase C is required for induction of 2-5A synthetase by recombinant interferon-alpha A in Daudi cells. Faltynek, C.R., Princler, G.L., Gusella, G.L., Varesio, L., Radzioch, D. J. Biol. Chem. (1989)
- Opposite effects of recombinant interferon-alpha A and deoxycoformycin on adenosine deaminase activity in the Daudi B lymphoblastoid cell line. Faltynek, C.R. Blood (1988)
- Antiviral effects of highly purified bacteria-derived human leukocyte interferons (subtypes A and D) and a human fibroblast interferon against herpes virus infection of the rabbit eye. Grabner, G., Smolin, G., Okumoto, M., Stebbing, N. Curr. Eye Res. (1982)
- Induction of cytokine production by different Staphylococcal strains. Megyeri, K., Mándi, Y., Degré, M., Rosztóczy, I. Cytokine (2002)
- Construction and activity of phosphorylatable human interferon-alpha B2 and interferon-alpha A/D. Wang, P., Izotova, L., Mariano, T.M., Donnelly, R.J., Pestka, S. J. Interferon Res. (1994)
- Involvement of LEU13 in interferon-induced refractoriness of human RSa cells to cell killing by X rays. Kita, K., Sugaya, S., Zhai, L., Wu, Y.P., Wano, C., Chigira, S., Nomura, J., Takahashi, S., Ichinose, M., Suzuki, N. Radiat. Res. (2003)
- Molecular deletion of 9p sequences in non-small cell lung cancer and malignant mesothelioma. Center, R., Lukeis, R., Dietzsch, E., Gillespie, M., Garson, O.M. Genes Chromosomes Cancer (1993)