Gene Review:
IGFALS - insulin-like growth factor binding protein...
Homo sapiens
Synonyms:
ACLSD, ALS, Insulin-like growth factor-binding protein complex acid labile subunit
Bourcigaux,
To,
Charbonnel,
Firth,
Draghi,
Clemmons,
Arnault-Ouary,
Cisternino,
Tatò,
Henriksen,
Lomeo,
Holman,
Van den Berghe,
Stewart,
Ganeshprasad,
Cavallo,
Christol,
Baxter,
Juul,
Møller,
Weekers,
Firth,
Becker,
Périn,
Bernasconi,
Lauriola,
Baxter,
Baxter,
De Luca,
Scarcella,
Wouters,
Hawker,
Baxter,
Veldhuis,
Bowers,
Le Bouc,
- Regulation of the insulin-like growth factors and their binding proteins by glucocorticoid and growth hormone in nonislet cell tumor hypoglycemia. Baxter, R.C., Holman, S.R., Corbould, A., Stranks, S., Ho, P.J., Braund, W. J. Clin. Endocrinol. Metab. (1995)
- The acid-labile subunit of human ternary insulin-like growth factor-binding protein complex in girls with central precocious puberty before and during gonadotropin-releasing hormone analog therapy. Cisternino, M., Draghi, M., Lauriola, S., Scarcella, D., Bernasconi, S., Cavallo, L., De Luca, F., Lomeo, A., Tatò, L. J. Clin. Endocrinol. Metab. (2002)
- Acid-labile subunit in growth hormone excess and deficiency in adults: evaluation of its diagnostic value in comparison with insulin-like growth factor (IGF)-I and IGF-binding protein-3. Fukuda, I., Hizuka, N., Itoh, E., Yasumoto, K., Ishikawa, Y., Murakami, Y., Sata, A., Takano, K. Endocr. J. (2002)
- A paradoxical gender dissociation within the growth hormone/insulin-like growth factor I axis during protracted critical illness. Van den Berghe, G., Baxter, R.C., Weekers, F., Wouters, P., Bowers, C.Y., Veldhuis, J.D. J. Clin. Endocrinol. Metab. (2000)
- The acid-labile subunit of the ternary insulin-like growth factor complex in cirrhosis: relation to liver dysfunction. Møller, S., Juul, A., Becker, U., Henriksen, J.H. J. Hepatol. (2000)
- Primary acid-labile subunit deficiency due to recessive IGFALS mutations results in postnatal growth deficit associated with low circulating insulin growth factor (IGF)-I, IGF binding protein-3 levels, and hyperinsulinemia. Heath, K.E., Argente, J., Barrios, V., Pozo, J., Díaz-González, F., Martos-Moreno, G.A., Caimari, M., Gracia, R., Campos-Barros, A. J. Clin. Endocrinol. Metab. (2008)
- Low levels of the 150-kD insulin-like growth factor binding protein 3 ternary complex in patients with anorexia nervosa: effect of partial weight recovery. Støving, R.K., Hangaard, J., Hagen, C., Flyvbjerg, A. Horm. Res. (2003)
- BMAA selectively injures motor neurons via AMPA/kainate receptor activation. Rao, S.D., Banack, S.A., Cox, P.A., Weiss, J.H. Exp. Neurol. (2006)
- Therapeutic potential of RNA interference for neurological disorders. Sah, D.W. Life Sci. (2006)
- Longitudinal predictors of psychological distress and self-esteem in people with ALS. Goldstein, L.H., Atkins, L., Landau, S., Brown, R.G., Leigh, P.N. Neurology (2006)
- The ALSSQOL: balancing physical and nonphysical factors in assessing quality of life in ALS. Simmons, Z., Felgoise, S.H., Bremer, B.A., Walsh, S.M., Hufford, D.J., Bromberg, M.B., David, W., Forshew, D.A., Heiman-Patterson, T.D., Lai, E.C., McCluskey, L. Neurology (2006)
- ALS: A Disease of Motor Neurons and Their Nonneuronal Neighbors. Boill??e, S., Vande Velde, C., Cleveland, D.W. Neuron (2006)
- Familial ALS-superoxide dismutases associate with mitochondria and shift their redox potentials. Ferri, A., Cozzolino, M., Crosio, C., Nencini, M., Casciati, A., Gralla, E.B., Rotilio, G., Valentine, J.S., Carrì, M.T. Proc. Natl. Acad. Sci. U.S.A. (2006)
- The acid-labile subunit of the serum insulin-like growth factor-binding protein complexes. Structural determination by molecular modeling and electron microscopy. Janosi, J.B., Ramsland, P.A., Mott, M.R., Firth, S.M., Baxter, R.C., Delhanty, P.J. J. Biol. Chem. (1999)
- N-Linked glycosylation and sialylation of the acid-labile subunit. Role in complex formation with insulin-like growth factor (IGF)-binding protein-3 and the IGFs. Janosi, J.B., Firth, S.M., Bond, J.J., Baxter, R.C., Delhanty, P.J. J. Biol. Chem. (1999)
- Insulin-like growth factor binding proteins as glucoregulators. Baxter, R.C. Metab. Clin. Exp. (1995)
- Characterization of the IGF system in 15 patients with Alström syndrome. Maffei, P., Boschetti, M., Marshall, J.D., Paisey, R.B., Beck, S., Resmini, E., Collin, G.B., Naggert, J.K., Milan, G., Vettor, R., Minuto, F., Sicolo, N., Barreca, A. Clin. Endocrinol. (Oxf) (2007)
- Protective effect of metabotropic glutamate receptor inhibition on amyotrophic lateral sclerosis-cerebrospinal fluid toxicity in vitro. Anneser, J.M., Chahli, C., Borasio, G.D. Neuroscience (2006)
- Clinical pharmacokinetics of intravenous and oral 9-amino-1,2,3,4-tetrahydroacridine, tacrine. Hartvig, P., Askmark, H., Aquilonius, S.M., Wiklund, L., Lindström, B. Eur. J. Clin. Pharmacol. (1990)
- Conservation of a growth hormone-responsive promoter element in the human and mouse acid-labile subunit genes. Suwanichkul, A., Boisclair, Y.R., Olney, R.C., Durham, S.K., Powell, D.R. Endocrinology (2000)
- Insulin-like growth factor binding protein-3: factors affecting binary and ternary complex formation. Holman, S.R., Baxter, R.C. Growth Regul. (1996)
- Structure and functional expression of the acid-labile subunit of the insulin-like growth factor-binding protein complex. Leong, S.R., Baxter, R.C., Camerato, T., Dai, J., Wood, W.I. Mol. Endocrinol. (1992)
- The role of the acid-labile subunit in regulating insulin-like growth factor transport across human umbilical vein endothelial cell monolayers. Payet, L.D., Firth, S.M., Baxter, R.C. J. Clin. Endocrinol. Metab. (2004)
- Isolation of the cDNA encoding the acid labile subunit (ALS) of the 150 kDa IGF-binding protein complex in cattle and ALS regulation during the transition from pregnancy to lactation. Kim, J.W., Rhoads, R.P., Segoale, N., Kristensen, N.B., Bauman, D.E., Boisclair, Y.R. J. Endocrinol. (2006)
- Acid-labile subunit of human insulin-like growth factor-binding protein complex: measurement, molecular, and clinical evaluation. Khosravi, M.J., Diamandi, A., Mistry, J., Krishna, R.G., Khare, A. J. Clin. Endocrinol. Metab. (1997)
- Structural determinants of ligand and cell surface binding of insulin-like growth factor-binding protein-3. Firth, S.M., Ganeshprasad, U., Baxter, R.C. J. Biol. Chem. (1998)
- Insulin-like growth factor-binding protein 5 complexes with the acid-labile subunit. Role of the carboxyl-terminal domain. Twigg, S.M., Kiefer, M.C., Zapf, J., Baxter, R.C. J. Biol. Chem. (1998)
- Treatment of hypoglycemia using combined glucocorticoid and recombinant human growth hormone in a patient with a metastatic non-islet cell tumor hypoglycemia. Bourcigaux, N., Arnault-Ouary, G., Christol, R., Périn, L., Charbonnel, B., Le Bouc, Y. Clinical therapeutics. (2005)
- High molecular weight insulin-like growth factor binding protein complex. Purification and properties of the acid-labile subunit from human serum. Baxter, R.C., Martin, J.L., Beniac, V.A. J. Biol. Chem. (1989)
- Ligand-binding characteristics of recombinant amino- and carboxyl-terminal fragments of human insulin-like growth factor-binding protein-3. Galanis, M., Firth, S.M., Bond, J., Nathanielsz, A., Kortt, A.A., Hudson, P.J., Baxter, R.C. J. Endocrinol. (2001)
- Complex formation by human insulin-like growth factor-binding protein-3 and human acid-labile subunit in growth hormone-deficient rats. Lewitt, M.S., Saunders, H., Phuyal, J.L., Baxter, R.C. Endocrinology (1994)
- Mutagenesis of basic amino acids in the carboxyl-terminal region of insulin-like growth factor binding protein-5 affects acid-labile subunit binding. Firth, S.M., Clemmons, D.R., Baxter, R.C. Endocrinology (2001)
- The effects of recombinant human IGF-I administration on concentrations of acid labile subunit, IGF binding protein-3, IGF-I, IGF-II and proteolysis of IGF binding protein-3 in adolescents with insulin-dependent diabetes mellitus. Cheetham, T.D., Holly, J.M., Baxter, R.C., Meadows, K., Jones, J., Taylor, A.M., Dunger, D.B. J. Endocrinol. (1998)
- Thirty-day monitoring of insulin-like growth factors and their binding proteins in intensive care unit patients. Baxter, R.C., Hawker, F.H., To, C., Stewart, P.M., Holman, S.R. Growth Horm. IGF Res. (1998)
- Purified rat acid-labile subunit and recombinant human insulin-like growth factor (IGF)-binding protein-3 can form a 150-kilodalton binary complex in vitro in the absence of IGFs. Lee, C.Y., Rechler, M.M. Endocrinology (1995)
- The high molecular weight insulin-like growth factor-binding protein complex: epitope mapping, immunoassay, and preliminary clinical evaluation. Khosravi, J., Diamandi, A., Mistry, J., Krischna, R.G. J. Clin. Endocrinol. Metab. (1999)