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Gene Review

TGFB1  -  transforming growth factor, beta 1

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Disease relevance of TGFB1


High impact information on TGFB1


Chemical compound and disease context of TGFB1


Biological context of TGFB1


Anatomical context of TGFB1


Associations of TGFB1 with chemical compounds


Regulatory relationships of TGFB1


Other interactions of TGFB1


Analytical, diagnostic and therapeutic context of TGFB1


  1. Sequence and chromosomal localisation of the gene encoding ovine latent transforming growth factor-beta 1. Woodall, C.J., McLaren, L.J., Watt, N.J. Gene (1994) [Pubmed]
  2. Transforming growth factor-beta activity in sheep lung lymph during the development of pulmonary hypertension. Perkett, E.A., Lyons, R.M., Moses, H.L., Brigham, K.L., Meyrick, B. J. Clin. Invest. (1990) [Pubmed]
  3. Renal renin-angiotensin system dysregulation caused by partial bladder outlet obstruction in fetal sheep. Gobet, R., Park, J.M., Nguyen, H.T., Chang, B., Cisek, L.J., Peters, C.A. Kidney Int. (1999) [Pubmed]
  4. Expression of transforming growth factor-beta mRNAs and proteins in pulmonary vascular remodeling in the sheep air embolization model of pulmonary hypertension. Perkett, E.A., Pelton, R.W., Meyrick, B., Gold, L.I., Miller, D.A. Am. J. Respir. Cell Mol. Biol. (1994) [Pubmed]
  5. Serotonin mechanisms in heart valve disease I: serotonin-induced up-regulation of transforming growth factor-beta1 via G-protein signal transduction in aortic valve interstitial cells. Jian, B., Xu, J., Connolly, J., Savani, R.C., Narula, N., Liang, B., Levy, R.J. Am. J. Pathol. (2002) [Pubmed]
  6. Aortic valve endothelial cells undergo transforming growth factor-beta-mediated and non-transforming growth factor-beta-mediated transdifferentiation in vitro. Paranya, G., Vineberg, S., Dvorin, E., Kaushal, S., Roth, S.J., Rabkin, E., Schoen, F.J., Bischoff, J. Am. J. Pathol. (2001) [Pubmed]
  7. Estrogen replacement inhibits intimal hyperplasia and the accumulation and effects of transforming growth factor beta1. Selzman, C.H., Gaynor, J.S., Turner, A.S., Whitehill, T.A., Horwitz, L.D., Harken, A.H. J. Surg. Res. (1998) [Pubmed]
  8. The in utero correction of unilateral coronal craniosynostosis. Stelnicki, E.J., Vanderwall, K., Harrison, M.R., Longaker, M.T., Kaban, L.B., Hoffman, W.Y. Plast. Reconstr. Surg. (1998) [Pubmed]
  9. Transforming growth factor beta treatment decreases ACTH receptors on ovine adrenocortical cells. Rainey, W.E., Viard, I., Saez, J.M. J. Biol. Chem. (1989) [Pubmed]
  10. Transforming growth factor beta 1 inhibits fetal lamb ductus arteriosus smooth muscle cell migration. Tannenbaum, J.E., Waleh, N.S., Mauray, F., Breuss, J., Pytela, R., Kramer, R.H., Clyman, R.I. Pediatr. Res. (1995) [Pubmed]
  11. Early gestational expression of transforming growth factor beta isoforms by the ovine placenta. Doré, J.J., Wilkinson, J.E., Godkin, J.D. Biol. Reprod. (1995) [Pubmed]
  12. Deregulation of renal transforming growth factor-beta1 after experimental short-term ureteric obstruction in fetal sheep. Yang, S.P., Woolf, A.S., Quinn, F., Winyard, P.J. Am. J. Pathol. (2001) [Pubmed]
  13. Regulation of insulin-like growth factor-binding protein-5 by insulin-like growth factor I and interleukin-1alpha in ovine articular chondrocytes. Sunic, D., McNeil, J.D., Rayner, T.E., Andress, D.L., Belford, D.A. Endocrinology (1998) [Pubmed]
  14. Effect of transforming growth factor beta-1 on the cholesterol side-chain cleavage system in the adrenal gland of sheep fetuses and newborns. Naaman-Reperant, E., Hales, D.B., Durand, P. Endocrinology (1996) [Pubmed]
  15. Transforming growth factor-beta inhibits steroid 17 alpha-hydroxylase cytochrome P-450 expression in ovine adrenocortical cells. Rainey, W.E., Naville, D., Saez, J.M., Carr, B.R., Byrd, W., Magness, R.R., Mason, J.I. Endocrinology (1990) [Pubmed]
  16. Reversal of lipopolysaccharide-analog-induced antibody suppression by anti-transforming growth factor beta and indomethacin. Odean, M.J., Johnson, A.G., Mohrman, M., Hasegawa, A. Infect. Immun. (1995) [Pubmed]
  17. Transforming growth factor-beta protein and messenger RNA expression is increased in the closing ductus arteriosus. Tannenbaum, J.E., Waleh, N.S., Mauray, F., Gold, L., Perkett, E.A., Clyman, R.I. Pediatr. Res. (1996) [Pubmed]
  18. Effects of insulin-like growth factor I, platelet-derived growth factor, fibroblast growth factor, and transforming growth factor-beta on thymidine incorporation into fetal liver cells. Congote, L.F. Exp. Hematol. (1987) [Pubmed]
  19. Atrial (ANP) and brain natriuretic peptide (BNP) expression after myocardial infarction in sheep: ANP is synthesized by fibroblasts infiltrating the infarct. Cameron, V.A., Rademaker, M.T., Ellmers, L.J., Espiner, E.A., Nicholls, M.G., Richards, A.M. Endocrinology (2000) [Pubmed]
  20. Ontogeny of vascular growth factors in perinatal sheep myocardium. van Natta, T.L., Ralphe, J.C., Mascio, C.E., Bedell, K.A., Scholz, T.D., Segar, J.L. J. Soc. Gynecol. Investig. (2004) [Pubmed]
  21. Deep dermal burn injury results in scarless wound healing in the ovine fetus. Fraser, J.F., Cuttle, L., Kempf, M., Phillips, G.E., O'Rourke, P.K., Choo, K., Hayes, M.T., Kimble, R.M. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. (2005) [Pubmed]
  22. Quantitative evaluation of endothelial progenitors and cardiac valve endothelial cells: proliferation and differentiation on poly-glycolic acid/poly-4-hydroxybutyrate scaffold in response to vascular endothelial growth factor and transforming growth factor beta1. Dvorin, E.L., Wylie-Sears, J., Kaushal, S., Martin, D.P., Bischoff, J. Tissue engineering. (2003) [Pubmed]
  23. In vivo analysis of a superantigen-induced T cell suppressor factor. Hu, H.L., Cornwell, W.D., Rogers, T.J., Lin, Y.S. Cell. Immunol. (1996) [Pubmed]
  24. Wound healing in the fetus. Possible role for inflammatory macrophages and transforming growth factor-beta isoforms. Longaker, M.T., Bouhana, K.S., Harrison, M.R., Danielpour, D., Roberts, A.B., Banda, M.J. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society (1994) [Pubmed]
  25. Transforming growth factor-beta regulates increased ductus arteriosus endothelial glycosaminoglycan synthesis and a post-transcriptional mechanism controls increased smooth muscle fibronectin, features associated with intimal proliferation. Boudreau, N., Clausell, N., Boyle, J., Rabinovitch, M. Lab. Invest. (1992) [Pubmed]
  26. Tissue-specific and developmental regulation of transforming growth factor-beta1 expression in fetal lamb ductus arteriosus endothelial cells. Zhou, B., Coulber, C., Rabinovitch, M. Pediatr. Res. (1998) [Pubmed]
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