Gene Review:
P2RX3 - purinergic receptor P2X, ligand gated ion...
Homo sapiens
Synonyms:
ATP receptor, P2X purinoceptor 3, P2X3, Purinergic receptor
North,
Lee,
Park,
Kong,
Kim,
Han,
Jarvis,
Burgard,
McGaraughty,
Honore,
Lynch,
Brennan,
Subieta,
Van Biesen,
Cartmell,
Bianchi,
Niforatos,
Kage,
Yu,
Mikusa,
Wismer,
Zhu,
Chu,
Lee,
Stewart,
Polakowski,
Cox,
Kowaluk,
Williams,
Sullivan,
Faltynek,
Honore,
Mikusa,
Bianchi,
McDonald,
Cartmell,
Faltynek,
Jarvis,
Burnstock,
Morikawa,
Sluyter,
Barden,
Wiley,
Mason,
Bourke,
Kemp,
- Selective modulation of ligand-gated P2X purinoceptor channels by acute hypoxia is mediated by reactive oxygen species. Mason, H.S., Bourke, S., Kemp, P.J. Mol. Pharmacol. (2004)
- Immunocytochemical localization of the vanilloid receptor 1 (VR1): relationship to neuropeptides, the P2X3 purinoceptor and IB4 binding sites. Guo, A., Vulchanova, L., Wang, J., Li, X., Elde, R. Eur. J. Neurosci. (1999)
- Capsaicin receptor VR1 and ATP-gated ion channel P2X3 in human urinary bladder. Yiangou, Y., Facer, P., Ford, A., Brady, C., Wiseman, O., Fowler, C.J., Anand, P. BJU international. (2001)
- Baculovirus expression provides direct evidence for heteromeric assembly of P2X2 and P2X3 receptors. Radford, K.M., Virginio, C., Surprenant, A., North, R.A., Kawashima, E. J. Neurosci. (1997)
- Up-regulation of P2X3 receptor during stretch of bladder urothelial cells from patients with interstitial cystitis. Sun, Y., Chai, T.C. J. Urol. (2004)
- Molecular physiology of P2X receptors. North, R.A. Physiol. Rev. (2002)
- Distinct ATP receptors on pain-sensing and stretch-sensing neurons. Cook, S.P., Vulchanova, L., Hargreaves, K.M., Elde, R., McCleskey, E.W. Nature (1997)
- Coexpression of P2X2 and P2X3 receptor subunits can account for ATP-gated currents in sensory neurons. Lewis, C., Neidhart, S., Holy, C., North, R.A., Buell, G., Surprenant, A. Nature (1995)
- The voltage-gated sodium channel Na(v)1.9 is an effector of peripheral inflammatory pain hypersensitivity. Amaya, F., Wang, H., Costigan, M., Allchorne, A.J., Hatcher, J.P., Egerton, J., Stean, T., Morisset, V., Grose, D., Gunthorpe, M.J., Chessell, I.P., Tate, S., Green, P.J., Woolf, C.J. J. Neurosci. (2006)
- Monocyte-derived multinucleated giant cells and sarcoidosis. Okamoto, H., Mizuno, K., Horio, T. J. Dermatol. Sci. (2003)
- Molecular characterization and pharmacological properties of the human P2X3 purinoceptor. Garcia-Guzman, M., Stühmer, W., Soto, F. Brain Res. Mol. Brain Res. (1997)
- A-317491, a novel potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors, reduces chronic inflammatory and neuropathic pain in the rat. Jarvis, M.F., Burgard, E.C., McGaraughty, S., Honore, P., Lynch, K., Brennan, T.J., Subieta, A., Van Biesen, T., Cartmell, J., Bianchi, B., Niforatos, W., Kage, K., Yu, H., Mikusa, J., Wismer, C.T., Zhu, C.Z., Chu, K., Lee, C.H., Stewart, A.O., Polakowski, J., Cox, B.F., Kowaluk, E., Williams, M., Sullivan, J., Faltynek, C. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Characterization of Ca2+ influx through recombinant P2X receptor in C6BU-1 cells. Ueno, S., Koizumi, S., Inoue, K. Br. J. Pharmacol. (1998)
- Capsaicin receptor VR1 and ATP purinoceptor P2X3 in painful and nonpainful human tooth pulp. Renton, T., Yiangou, Y., Baecker, P.A., Ford, A.P., Anand, P. Journal of orofacial pain. (2003)
- Detection of P2X purinergic receptors on human B lymphocytes. Sluyter, R., Barden, J.A., Wiley, J.S. Cell Tissue Res. (2001)
- Differential expression of P2X-purinoceptor subtypes in circular and longitudinal muscle of canine colon. Lee, H.K., Ro, S., Keef, K.D., Kathy, K.D., Kim, Y.H., Kim, H.W., Horowitz, B., Sanders, K.M. Neurogastroenterol. Motil. (2005)
- The purinergic component of human vas deferens contraction. Banks, F.C., Knight, G.E., Calvert, R.C., Thompson, C.S., Morgan, R.J., Burnstock, G. Fertil. Steril. (2006)
- Anandamide acts as an intracellular messenger amplifying Ca2+ influx via TRPV1 channels. van der Stelt, M., Trevisani, M., Vellani, V., De Petrocellis, L., Schiano Moriello, A., Campi, B., McNaughton, P., Geppetti, P., Di Marzo, V. EMBO J. (2005)
- ATP-stimulated release of interleukin (IL)-1beta and IL-18 requires priming by lipopolysaccharide and is independent of caspase-1 cleavage. Mehta, V.B., Hart, J., Wewers, M.D. J. Biol. Chem. (2001)
- Purinergic P2 receptors as targets for novel analgesics. Burnstock, G. Pharmacol. Ther. (2006)
- Co-expression of P2X1 and P2X5 receptor subunits reveals a novel ATP-gated ion channel. Torres, G.E., Haines, W.R., Egan, T.M., Voigt, M.M. Mol. Pharmacol. (1998)
- Oncostatin M in the development of the nervous system. Morikawa, Y. Anatomical science international / Japanese Association of Anatomists. (2005)
- Expression of P2 receptors in human B cells and Epstein-Barr virus-transformed lymphoblastoid cell lines. Lee, D.H., Park, K.S., Kong, I.D., Kim, J.W., Han, B.G. BMC Immunol. (2006)
- Membrane-specific expression of functional purinergic receptors in normal human nasal epithelial cells. Kim, C.H., Kim, S.S., Choi, J.Y., Shin, J.H., Kim, J.Y., Namkung, W., Lee, J.G., Lee, M.G., Yoon, J.H. Am. J. Physiol. Lung Cell Mol. Physiol. (2004)
- TNP-ATP, a potent P2X3 receptor antagonist, blocks acetic acid-induced abdominal constriction in mice: comparison with reference analgesics. Honore, P., Mikusa, J., Bianchi, B., McDonald, H., Cartmell, J., Faltynek, C., Jarvis, M.F. Pain (2002)