Gene Review:
SDHB - succinate dehydrogenase complex, subunit B...
Homo sapiens
Synonyms:
CWS2, IP, Ip, Iron-sulfur subunit of complex II, PGL4, ...
Gimm,
Koch,
Januszewicz,
Opocher,
Neumann,
Elder,
Elder,
Larsson,
Schiavi,
Savvoukidis,
Trabalzini,
Grego,
Piazza,
Amist??,
Dematt??,
Piano,
Cecchini,
Erlic,
DE Lazzari,
Mantero,
Opocher,
Pollard,
Wortham,
Barclay,
Alam,
Elia,
Manek,
Poulsom,
Tomlinson,
Baysal,
Isobe,
Nissato,
Tatsuno,
Yashiro,
Takekoshi,
Kawakami,
- Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma. Astuti, D., Latif, F., Dallol, A., Dahia, P.L., Douglas, F., George, E., Sköldberg, F., Husebye, E.S., Eng, C., Maher, E.R. Am. J. Hum. Genet. (2001)
- Early-onset renal cell carcinoma as a novel extraparaganglial component of SDHB-associated heritable paraganglioma. Vanharanta, S., Buchta, M., McWhinney, S.R., Virta, S.K., Peçzkowska, M., Morrison, C.D., Lehtonen, R., Januszewicz, A., Järvinen, H., Juhola, M., Mecklin, J.P., Pukkala, E., Herva, R., Kiuru, M., Nupponen, N.N., Aaltonen, L.A., Neumann, H.P., Eng, C. Am. J. Hum. Genet. (2004)
- Evidence of increased microvessel density and activation of the hypoxia pathway in tumours from the hereditary leiomyomatosis and renal cell cancer syndrome. Pollard, P., Wortham, N., Barclay, E., Alam, A., Elia, G., Manek, S., Poulsom, R., Tomlinson, I. J. Pathol. (2005)
- Investigation of the role of SDHB inactivation in sporadic phaeochromocytoma and neuroblastoma. Astuti, D., Morris, M., Krona, C., Abel, F., Gentle, D., Martinsson, T., Kogner, P., Neumann, H.P., Voutilainen, R., Eng, C., Rustin, P., Latif, F., Maher, E.R. Br. J. Cancer (2004)
- Strength, skeletal muscle composition, and enzyme activity in multiple sclerosis. Kent-Braun, J.A., Ng, A.V., Castro, M., Weiner, M.W., Gelinas, D., Dudley, G.A., Miller, R.G. J. Appl. Physiol. (1997)
- Crystal structure of mitochondrial respiratory membrane protein complex II. Sun, F., Huo, X., Zhai, Y., Wang, A., Xu, J., Su, D., Bartlam, M., Rao, Z. Cell (2005)
- Total-genome analysis of BRCA1/2-related invasive carcinomas of the breast identifies tumor stroma as potential landscaper for neoplastic initiation. Weber, F., Shen, L., Fukino, K., Patocs, A., Mutter, G.L., Caldes, T., Eng, C. Am. J. Hum. Genet. (2006)
- Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations. Pollard, P.J., Brière, J.J., Alam, N.A., Barwell, J., Barclay, E., Wortham, N.C., Hunt, T., Mitchell, M., Olpin, S., Moat, S.J., Hargreaves, I.P., Heales, S.J., Chung, Y.L., Griffiths, J.R., Dalgleish, A., McGrath, J.A., Gleeson, M.J., Hodgson, S.V., Poulsom, R., Rustin, P., Tomlinson, I.P. Hum. Mol. Genet. (2005)
- The pressure rises: update on the genetics of phaeochromocytoma. Maher, E.R., Eng, C. Hum. Mol. Genet. (2002)
- Enzymatic activity and stability of D-fructose dehydrogenase and sarcosine dehydrogenase immobilized onto giant vesicles. Kato, K., Walde, P., Mitsui, H., Higashi, N. Biotechnol. Bioeng. (2003)
- Cholestyramine as an antidote against paracetamol-induced hepato- and nephrotoxicity in the rat. Siegers, C.P., Möller-Hartmann, W. Toxicol. Lett. (1989)
- Effect of partial oxygen supply on mitochondrial electron transport system during complete cardiac ischemia. Konuralp, C., Güner, S., Cakatay, U., Konuralp, Z., Yapící, N., Maçika, H., Aydoğan, H., Aykut-Aka, S., Alhan, C., Gültepe, M., Eren, E.E. Journal of cardiac surgery. (1999)
- Familial malignant catecholamine-secreting paraganglioma with prolonged survival associated with mutation in the succinate dehydrogenase B gene. Young, A.L., Baysal, B.E., Deb, A., Young, W.F. J. Clin. Endocrinol. Metab. (2002)
- No mutations but an increased frequency of SDHx polymorphisms in patients with sporadic and familial medullary thyroid carcinoma. Montani, M., Schmitt, A.M., Schmid, S., Locher, T., Saremaslani, P., Heitz, P.U., Komminoth, P., Perren, A. Endocr. Relat. Cancer (2005)
- Gross SDHB deletions in patients with paraganglioma detected by multiplex PCR: a possible hot spot? Cascón, A., Montero-Conde, C., Ruiz-Llorente, S., Mercadillo, F., Letón, R., Rodríguez-Antona, C., Martínez-Delgado, B., Delgado, M., Díez, A., Rovira, A., Díaz, J.A., Robledo, M. Genes Chromosomes Cancer (2006)
- On the association of succinate dehydrogenase mutations with hereditary paraganglioma. Baysal, B.E. Trends Endocrinol. Metab. (2003)
- Paraganglioma Syndrome: SDHB, SDHC, and SDHD Mutations in Head and Neck Paragangliomas. Schiavi, F., Savvoukidis, T., Trabalzini, F., Grego, F., Piazza, M., Amist??, P., Dematt??, S., Piano, A.D., Cecchini, M.E., Erlic, Z., DE Lazzari, P., Mantero, F., Opocher, G. Ann. N. Y. Acad. Sci. (2006)
- Expression of mRNAs for Succinate Dehydrogenase Subunits and Related Genes in Pheochromocytoma. Isobe, K., Nissato, S., Tatsuno, I., Yashiro, T., Takekoshi, K., Kawakami, Y. Ann. N. Y. Acad. Sci. (2006)
- SDHB, SDHC, and SDHD mutation screen in sporadic and familial head and neck paragangliomas. Mhatre, A.N., Li, Y., Feng, L., Gasperin, A., Lalwani, A.K. Clin. Genet. (2004)
- Studies on the assembly of complex II in yeast mitochondria using chimeric human/yeast genes for the iron-sulfur protein subunit. Saghbini, M., Broomfield, P.L., Scheffler, I.E. Biochemistry (1994)
- Variation in sorbitol accumulation and polyol-pathway activity in cultured human proximal tubule cells. Flath, M.C., Bylander, J.E., Sens, D.A. Diabetes (1992)
- Evaluation of the 3 alpha-hydroxysteroid dehydrogenase assay for ursodeoxycholic acid, and 7 oxo- and 12 oxo- bile acids. Haeffner, L.J., Gordon, S.J., Magen, J.S., Kowlessar, O.D. J. Lipid Res. (1980)
- Sensitivity to sensorimotor gating-disruptive effects of apomorphine in two outbred parental rat strains and their F1 and N2 progeny. Swerdlow, N.R., Platten, A., Hanlon, F.M., Martinez, Z.A., Printz, M.P., Auerbach, P. Neuropsychopharmacology (2003)
- Characterization of the human SDHC gene encoding of the integral membrane proteins of succinate-quinone oxidoreductase in mitochondria. Elbehti-Green, A., Au, H.C., Mascarello, J.T., Ream-Robinson, D., Scheffler, I.E. Gene (1998)
- The genetic basis of pheochromocytoma. Gimm, O., Koch, C.A., Januszewicz, A., Opocher, G., Neumann, H.P. Frontiers of hormone research. (2004)
- Molecular genetic analysis of FIH-1, FH, and SDHB candidate tumour suppressor genes in renal cell carcinoma. Morris, M.R., Maina, E., Morgan, N.V., Gentle, D., Astuti, D., Moch, H., Kishida, T., Yao, M., Schraml, P., Richards, F.M., Latif, F., Maher, E.R. J. Clin. Pathol. (2004)
- Pheochromocytoma and functional paraganglioma syndrome: no longer the 10% tumor. Elder, E.E., Elder, G., Larsson, C. Journal of surgical oncology. (2005)
- SDHD mutations in head and neck paragangliomas result in destabilization of complex II in the mitochondrial respiratory chain with loss of enzymatic activity and abnormal mitochondrial morphology. Douwes Dekker, P.B., Hogendoorn, P.C., Kuipers-Dijkshoorn, N., Prins, F.A., van Duinen, S.G., Taschner, P.E., van der Mey, A.G., Cornelisse, C.J. J. Pathol. (2003)
- Nocturnal but not short hours quotidian hemodialysis requires an elevated dialysate calcium concentration. Al-Hejaili, F., Kortas, C., Leitch, R., Heidenheim, A.P., Clement, L., Nesrallah, G., Lindsay, R.M. J. Am. Soc. Nephrol. (2003)