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MeSH Review


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Disease relevance of Phlebitis


Psychiatry related information on Phlebitis


High impact information on Phlebitis


Chemical compound and disease context of Phlebitis

  • Disposition of bisantrene in humans and rabbits: evidence for intravascular deposition of drug as a cause of phlebitis [13].
  • Phlebitis occurred at the site of infusion when the dose of dipyridamole exceeded 13.5 mg/kg/72 h [14].
  • Adverse effects of cefazolin were carefully monitored: no rash, phlebitis, or emergence of resistant strains was observed [15].
  • In one patient in the cefoxitin-treated group, local phlebitis developed at the infusion site [16].
  • The toxic reactions to acyclovir consist of phlebitis, local irritation, and occasionally, reversible renal dysfunction [17].

Biological context of Phlebitis


Anatomical context of Phlebitis


Gene context of Phlebitis

  • After adjusting for age, subjects with VV tend to be younger and female, to more frequently have a history of phlebitis, and to report a family history of VV more frequently than control subjects [23].
  • Of the total of 21 episodes the SLE was considered to be active in 14, inactive in 6, and variable in a patient with recurring phlebitis [24].
  • The phlebitis rates for lines left in for 72 and 96 hours were not significantly different (3.3% vs 2.6%, p = 1.000) by Fisher's Exact Test and survival analysis [25].
  • Common early complications of EVLP are: local paraesthesia of the treated area in 92 legs (36.5%), ecchymosis and dyschromia in 58 legs (23.0%), superficial burn injury in 12 legs (4.8%), superficial phlebitis in four legs (1.6%), and localized hematoma in two legs (0.8%) at 3 weeks post-operatively [26].
  • RESULTS: Multiple sclerosis (MS) was found in 41 patients of whom 1 had periphlebitis retinae (PR) and 2 had venous sheathing (VS) [27].

Analytical, diagnostic and therapeutic context of Phlebitis


  1. A phase I-II trial of carboplatin and 5-fluorouracil combination chemotherapy in advanced carcinoma of the head and neck. Forastiere, A.A., Natale, R.B., Takasugi, B.J., Goren, M.P., Vogel, W.C., Kudla-Hatch, V. J. Clin. Oncol. (1987) [Pubmed]
  2. Modulation of vinblastine resistance in metastatic renal cell carcinoma with cyclosporine A or tamoxifen: a cancer and leukemia group B study. Samuels, B.L., Hollis, D.R., Rosner, G.L., Trump, D.L., Shapiro, C.L., Vogelzang, N.J., Schilsky, R.L. Clin. Cancer Res. (1997) [Pubmed]
  3. Efficacy of minocycline and EDTA lock solution in preventing catheter-related bacteremia, septic phlebitis, and endocarditis in rabbits. Raad, I., Hachem, R., Tcholakian, R.K., Sherertz, R. Antimicrob. Agents Chemother. (2002) [Pubmed]
  4. Ultrasonographic diagnosis of incomplete inferior vena caval thrombosis secondary to periphlebitis: the importance of a complete survey examination. Sonnenfeld, M., Finberg, H.J. Radiology. (1980) [Pubmed]
  5. Popliteal cysts in adults: a review. Handy, J.R. Semin. Arthritis Rheum. (2001) [Pubmed]
  6. A comparison of diazepam and phenoperidine in premedication for upper gastrointestinal endoscopy: a randomized double blind controlled study. Werner, D., Ratnaike, R.N., Lawson, M.J., Barrie, J., Streeter, J., Read, T., Grant, A.K. Eur. J. Clin. Pharmacol. (1982) [Pubmed]
  7. Response time and safety profile of pulsed oral methotrexate therapy in idiopathic retinal periphlebitis. Bali, T., Saxena, S., Kumar, D., Nath, R. European journal of ophthalmology. (2005) [Pubmed]
  8. Complications with heparin-lock needles. Couchonnal, G.J., Hodges, G.R., Barnes, W.G., Elmets, C.A., Clark, G.M. JAMA (1979) [Pubmed]
  9. Antimicrobial vs placebo prophylaxis in noncardiac thoracic surgery. Truesdale, R., D'Alessandri, R., Manuel, V., Daicoff, G., Kluge, R.M. JAMA (1979) [Pubmed]
  10. Hepatic veno-occlusive disease in a renal transplant patient receiving azathioprine. Marubbio, A.T., Danielson, B. Gastroenterology (1975) [Pubmed]
  11. Metabolic modulation of acute myocardial infarction. The ECLA (Estudios Cardiológicos Latinoamérica) Collaborative Group. Díaz, R., Paolasso, E.A., Piegas, L.S., Tajer, C.D., Moreno, M.G., Corvalán, R., Isea, J.E., Romero, G. Circulation (1998) [Pubmed]
  12. A double-blind, randomized, placebo-controlled trial of prostaglandin E1 in liver transplantation. Henley, K.S., Lucey, M.R., Normolle, D.P., Merion, R.M., McLaren, I.D., Crider, B.A., Mackie, D.S., Shieck, V.L., Nostrant, T.T., Brown, K.A. Hepatology (1995) [Pubmed]
  13. Disposition of bisantrene in humans and rabbits: evidence for intravascular deposition of drug as a cause of phlebitis. Powis, G., Kovach, J.S. Cancer Res. (1983) [Pubmed]
  14. Phase I clinical trial of a combination of dipyridamole and acivicin based upon inhibition of nucleoside salvage. Willson, J.K., Fischer, P.H., Tutsch, K., Alberti, D., Simon, K., Hamilton, R.D., Bruggink, J., Koeller, J.M., Tormey, D.C., Earhart, R.H. Cancer Res. (1988) [Pubmed]
  15. Antibiotic prophylaxis in vascular surgery. Kaiser, A.B., Clayson, K.R., Mulherin, J.L., Roach, A.C., Allen, T.R., Edwards, W.H., Dale, W.A. Ann. Surg. (1978) [Pubmed]
  16. Treatment of infections in hospitalized patients with ticarcillin plus clavulanic acid. A comparative study. Holloway, W.J. Am. J. Med. (1985) [Pubmed]
  17. Acyclovir. Pharmacology and clinical experience. Laskin, O.L. Arch. Intern. Med. (1984) [Pubmed]
  18. Preclinical antitumour activity and animal toxicology studies of rhizoxin, a novel tubulin-interacting agent. Hendriks, H.R., Plowman, J., Berger, D.P., Paull, K.D., Fiebig, H.H., Fodstad, O., Dreef-van der Meulen, H.C., Henrar, R.E., Pinedo, H.M., Schwartsmann, G. Ann. Oncol. (1992) [Pubmed]
  19. Dicloxacillin and erythromycin at high concentrations increase ICAM-1 expression by endothelial cells: a possible factor in the pathogenesis of infusion phlebitis. Lanbeck, P., Odenholt, I., Riesbeck, K. J. Antimicrob. Chemother. (2004) [Pubmed]
  20. Effects of human GM-CSF on neutrophil degranulation in vitro. Kaufman, S.E., DiPersio, J.F., Gasson, J.C. Exp. Hematol. (1989) [Pubmed]
  21. Reduction of postinfusion venous endothelial injury with intralipid. Fujiwara, T., Kawarasaki, H., Fonkalsrud, E.W. Surgery, gynecology & obstetrics. (1984) [Pubmed]
  22. Recurrent gouty phlebitis without articular gout. Pasero, G. Adv. Exp. Med. Biol. (1977) [Pubmed]
  23. Risk factors for chronic venous insufficiency: a dual case-control study. Scott, T.E., LaMorte, W.W., Gorin, D.R., Menzoian, J.O. J. Vasc. Surg. (1995) [Pubmed]
  24. Venous syndromes and pulmonary embolism in systemic lupus erythematosus. Gladman, D.D., Urowitz, M.B. Ann. Rheum. Dis. (1980) [Pubmed]
  25. Safety of prolonging peripheral cannula and i.v. tubing use from 72 hours to 96 hours. Lai, K.K. American journal of infection control. (1998) [Pubmed]
  26. Endovenous laser photocoagulation (EVLP) for varicose veins. Chang, C.J., Chua, J.J. Lasers in surgery and medicine. (2002) [Pubmed]
  27. Changes in the retinal veins in acute optic neuritis. Engell, T., Sellebjerg, F., Jensen, C. Acta neurologica Scandinavica. (1999) [Pubmed]
  28. Carumonam (Ro 17-2301; AMA-1080) compared with gentamicin for treatment of complicated urinary tract infections. Hoepelman, A.I., Bakker, L.J., Verhoef, J. Antimicrob. Agents Chemother. (1988) [Pubmed]
  29. Arcuate and interlobular phlebitis in renal allografts. Torbenson, M., Randhawa, P. Hum. Pathol. (2001) [Pubmed]
  30. Prevention of lidocaine-infusion phlebitis by heparin and hydrocortisone. Bassan, M.M., Sheikh-Hamad, D. Chest (1983) [Pubmed]
  31. Efficacy and safety of early versus late initiation of warfarin during heparin therapy in acute thromboembolism. Mohiuddin, S.M., Hilleman, D.E., Destache, C.J., Stoysich, A.M., Gannon, J.M., Sketch, M.H. Am. Heart J. (1992) [Pubmed]
  32. Use of oral uridine as a substitute for parenteral uridine rescue of 5-fluorouracil therapy, with and without the uridine phosphorylase inhibitor 5-benzylacyclouridine. Martin, D.S., Stolfi, R.L., Sawyer, R.C. Cancer Chemother. Pharmacol. (1989) [Pubmed]
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