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MeSH Review

Asia, Southeastern

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Disease relevance of Asia, Southeastern

  • Artesunate is a key antimalarial drug in the treatment of multidrug-resistant Plasmodium falciparum malaria in southeast Asia. We investigated the distribution of counterfeit artesunate tablets by use of the validated, simple, and inexpensive Fast Red TR dye technique [1].
  • EBV infection takes place much earlier in Uganda, where all children are infected before the age of 2 to 3 years, than in Southeast Asia, where nasopharyngeal carcinoma is prevalent [2].
  • Nine patients were drug addicts and 17 were children and young adults from Mediterranean countries or southeast Asia. During the acute phase of illness, serum bilirubin and SGPT levels did not differ from those in other patients with acute hepatitis A [3].
  • In this study, we examined a T cell epitope restricted by HLA-A*24, a major MHC class I allele, in Southeast Asia in a cohort of children admitted to a hospital with acute Dengue infection [4].
  • The plant hormone ethylene is believed to be responsible for the ability of rice to grow in the deepwater regions of Southeast Asia. Ethylene production is induced by hypoxia, which is caused by flooding, because of enhanced activity of 1-aminocyclopropane-1-carboxylic acid (ACC) synthase, the key enzyme in the ethylene biosynthetic pathway [5].

Psychiatry related information on Asia, Southeastern


High impact information on Asia, Southeastern

  • Complex polymorphisms in an approximately 330 kDa protein are linked to chloroquine-resistant P. falciparum in Southeast Asia and Africa [7].
  • The study compares the health and noncombat mortality of Ranch Hand veterans with a comparison group of Air Force veterans primarily involved with cargo missions in Southeast Asia but who were not exposed to herbicides [8].
  • Thiamine deficiency and malaria in adults from southeast Asia [9].
  • It was 0.6% in Asia Minor. Factor V Leiden was not found in any of 1600 chromosomes from Africa, Southeast Asia, Australasia, and the Americas [10].
  • In nonalcoholic cirrhotic patients from Japan and Southeast Asia, in whom hepatocellular carcinoma is endemic, an adenomatous hyperplastic nodule or a similar hyperplastic lesion that occurs in cirrhotic livers may be preneoplastic and already committed to malignant transformation [11].

Chemical compound and disease context of Asia, Southeastern


Biological context of Asia, Southeastern


Anatomical context of Asia, Southeastern


Associations of Asia, Southeastern with chemical compounds

  • Multicenter phase II trial of mitoxantrone in patients with advanced nasopharyngeal carcinoma in Southeast Asia: an Asian-Oceanian Clinical Oncology Association Group study [24].
  • Previous studies from Southeast Asia suggested that immunosuppressive therapy could be harmful, or at best of no value, and antiviral treatment with vidarabine, picibanil, or even interferon was also unsatisfactory [25].
  • The prevalence of lactose maldigestion is lowest in Scandinavia and Northwest Europe (3-8%) and close to 100% in most of Southeast Asia. In Europe the frequency increases in the southern and eastern directions, reaching 70% in southern Italy and Turkey [26].
  • The most frequent mutation of the core protein in HBV from Southeast Asia occurs at amino acid 97, changing an isoleucine (I) to a leucine (L) [27].
  • Results with a fructosamine kit for a group of diabetics in Southeast Asia [28].

Gene context of Asia, Southeastern


Analytical, diagnostic and therapeutic context of Asia, Southeastern


  1. Fake artesunate in southeast Asia. Newton, P., Proux, S., Green, M., Smithuis, F., Rozendaal, J., Prakongpan, S., Chotivanich, K., Mayxay, M., Looareesuwan, S., Farrar, J., Nosten, F., White, N.J. Lancet (2001) [Pubmed]
  2. Epstein-Barr virus behavior in different populations and implications for control of Epstein-Barr virus-associated tumors. de-Thé, G. Cancer Res. (1976) [Pubmed]
  3. Hepatitis A infection in chronic carriers of hepatitis B virus. Zachoval, R., Roggendorf, M., Deinhardt, F. Hepatology (1983) [Pubmed]
  4. T cell responses in dengue hemorrhagic fever: are cross-reactive T cells suboptimal? Mongkolsapaya, J., Duangchinda, T., Dejnirattisai, W., Vasanawathana, S., Avirutnan, P., Jairungsri, A., Khemnu, N., Tangthawornchaikul, N., Chotiyarnwong, P., Sae-Jang, K., Koch, M., Jones, Y., McMichael, A., Xu, X., Malasit, P., Screaton, G. J. Immunol. (2006) [Pubmed]
  5. Anaerobiosis and plant growth hormones induce two genes encoding 1-aminocyclopropane-1-carboxylate synthase in rice (Oryza sativa L.). Zarembinski, T.I., Theologis, A. Mol. Biol. Cell (1993) [Pubmed]
  6. Crisis intervention after the Tsunami in Phuket and Khao Lak. Bronisch, T., Maragkos, M., Freyer, C., Müller-Cyran, A., Butollo, W., Weimbs, R., Platiel, P. Crisis. (2006) [Pubmed]
  7. Complex polymorphisms in an approximately 330 kDa protein are linked to chloroquine-resistant P. falciparum in Southeast Asia and Africa. Su, X., Kirkman, L.A., Fujioka, H., Wellems, T.E. Cell (1997) [Pubmed]
  8. Health status of Air Force veterans occupationally exposed to herbicides in Vietnam. I. Physical health. Wolfe, W.H., Michalek, J.E., Miner, J.C., Rahe, A., Silva, J., Thomas, W.F., Grubbs, W.D., Lustik, M.B., Karrison, T.G., Roegner, R.H. JAMA (1990) [Pubmed]
  9. Thiamine deficiency and malaria in adults from southeast Asia. Krishna, S., Taylor, A.M., Supanaranond, W., Pukrittayakamee, S., ter Kuile, F., Tawfiq, K.M., Holloway, P.A., White, N.J. Lancet (1999) [Pubmed]
  10. World distribution of factor V Leiden. Rees, D.C., Cox, M., Clegg, J.B. Lancet (1995) [Pubmed]
  11. Emergence of malignant lesions within an adenomatous hyperplastic nodule in a cirrhotic liver. Observations in five cases. Arakawa, M., Kage, M., Sugihara, S., Nakashima, T., Suenaga, M., Okuda, K. Gastroenterology (1986) [Pubmed]
  12. Two-week dietary soy supplementation has an estrogenic effect on normal premenopausal breast. Hargreaves, D.F., Potten, C.S., Harding, C., Shaw, L.E., Morton, M.S., Roberts, S.A., Howell, A., Bundred, N.J. J. Clin. Endocrinol. Metab. (1999) [Pubmed]
  13. Oral artesunate dose-response relationship in acute falciparum malaria. Angus, B.J., Thaiaporn, I., Chanthapadith, K., Suputtamongkol, Y., White, N.J. Antimicrob. Agents Chemother. (2002) [Pubmed]
  14. Clinical phenotypes and molecular characterization of Hb H-Paksé disease. Viprakasit, V., Tanphaichitr, V.S., Pung-Amritt, P., Petrarat, S., Suwantol, L., Fisher, C., Higgs, D.R. Haematologica (2002) [Pubmed]
  15. Amphotericin B and itraconazole for treatment of disseminated Penicillium marneffei infection in human immunodeficiency virus-infected patients. Sirisanthana, T., Supparatpinyo, K., Perriens, J., Nelson, K.E. Clin. Infect. Dis. (1998) [Pubmed]
  16. In-vitro stability of beta-lactam antibiotics to hydrolysis by beta-lactamases of Neisseria gonorrhoeae from Southeast Asia. Wong, P.C., Ho, W.Y., Ng, W.W. Sexually transmitted diseases. (1985) [Pubmed]
  17. Evidence for multiple origins of the beta E-globin gene in Southeast Asia. Antonarakis, S.E., Orkin, S.H., Kazazian, H.H., Goff, S.C., Boehm, C.D., Waber, P.G., Sexton, J.P., Ostrer, H., Fairbanks, V.F., Chakravarti, A. Proc. Natl. Acad. Sci. U.S.A. (1982) [Pubmed]
  18. Selection pressure-driven evolution of the Epstein-Barr virus-encoded oncogene LMP1 in virus isolates from Southeast Asia. Burrows, J.M., Bromham, L., Woolfit, M., Piganeau, G., Tellam, J., Connolly, G., Webb, N., Poulsen, L., Cooper, L., Burrows, S.R., Moss, D.J., Haryana, S.M., Ng, M., Nicholls, J.M., Khanna, R. J. Virol. (2004) [Pubmed]
  19. Resistance to antimalarials in Southeast Asia and genetic polymorphisms in pfmdr1. Pickard, A.L., Wongsrichanalai, C., Purfield, A., Kamwendo, D., Emery, K., Zalewski, C., Kawamoto, F., Miller, R.S., Meshnick, S.R. Antimicrob. Agents Chemother. (2003) [Pubmed]
  20. Antimalarial multi-drug resistance in Asia: mechanisms and assessment. Uhlemann, A.C., Krishna, S. Curr. Top. Microbiol. Immunol. (2005) [Pubmed]
  21. Molecular biology of rice tungro viruses. Hull, R. Annual review of phytopathology. (1996) [Pubmed]
  22. Enteroviruses as agents of emerging infectious diseases. Palacios, G., Oberste, M.S. J. Neurovirol. (2005) [Pubmed]
  23. Molecular cytogenetic characterization of nasopharyngeal carcinoma cell lines and xenografts by comparative genomic hybridization and spectral karyotyping. Wong, N., Hui, A.B., Fan, B., Lo, K.W., Pang, E., Leung, S.F., Huang, D.P., Johnson, P.J. Cancer Genet. Cytogenet. (2003) [Pubmed]
  24. Multicenter phase II trial of mitoxantrone in patients with advanced nasopharyngeal carcinoma in Southeast Asia: an Asian-Oceanian Clinical Oncology Association Group study. Dugan, M., Choy, D., Ngai, A., Sham, J., Choi, P., Shiu, W., Leung, T., Teo, P., Prasad, U., Lee, S. J. Clin. Oncol. (1993) [Pubmed]
  25. Treatment of chronic type B hepatitis in Southeast Asia. Liaw, Y.F., Lin, S.M., Sheen, I.S., Chen, T.J., Chu, C.M. Am. J. Med. (1988) [Pubmed]
  26. The clinical significance of disaccharide maldigestion. Gudmand-Høyer, E. Am. J. Clin. Nutr. (1994) [Pubmed]
  27. Replication advantage and host factor-independent phenotypes attributable to a common naturally occurring capsid mutation (I97L) in human hepatitis B virus. Suk, F.M., Lin, M.H., Newman, M., Pan, S., Chen, S.H., Liu, J.D., Shih, C. J. Virol. (2002) [Pubmed]
  28. Results with a fructosamine kit for a group of diabetics in Southeast Asia. Tho, L.L., Koay, E.S., Thai, A.C., Candlish, J.K. Clin. Chem. (1987) [Pubmed]
  29. Molecular heterogeneity of glucose-6-phosphate dehydrogenase (G6PD) variants in the south of Thailand and identification of a novel variant (G6PD Songklanagarind). Laosombat, V., Sattayasevana, B., Janejindamai, W., Viprakasit, V., Shirakawa, T., Nishiyama, K., Matsuo, M. Blood Cells Mol. Dis. (2005) [Pubmed]
  30. Novel compound heterozygous SLC4A1 mutations in Thai patients with autosomal recessive distal renal tubular acidosis. Sritippayawan, S., Sumboonnanonda, A., Vasuvattakul, S., Keskanokwong, T., Sawasdee, N., Paemanee, A., Thuwajit, P., Wilairat, P., Nimmannit, S., Malasit, P., Yenchitsomanus, P.T. Am. J. Kidney Dis. (2004) [Pubmed]
  31. EGFR tyrosine kinase inhibitor AG1478 inhibits cell proliferation and arrests cell cycle in nasopharyngeal carcinoma cells. Zhu, X.F., Liu, Z.C., Xie, B.F., Li, Z.M., Feng, G.K., Yang, D., Zeng, Y.X. Cancer Lett. (2001) [Pubmed]
  32. The 'hot-spot' of Hb E [beta26(B8)Glu-->Lys] in Southeast Asia: beta-globin anomalies in the Lao Theung population of southern Laos. Flatz, G., Sanguansermsri, T., Sengchanh, S., Horst, D., Horst, J. Hemoglobin (2004) [Pubmed]
  33. The epidemiology and phenotype of Crohn's disease in the Chinese population. Leong, R.W., Lau, J.Y., Sung, J.J. Inflamm. Bowel Dis. (2004) [Pubmed]
  34. Optic disc hemorrhage in Asian glaucoma patients. Gazzard, G., Morgan, W., Devereux, J., Foster, P., Oen, F., Seah, S., Khaw, P.T., Chew, P. Journal of glaucoma. (2003) [Pubmed]
  35. Growth inhibition of nasopharyngeal carcinoma cells by EGF receptor tyrosine kinase inhibitors. Sun, Y., Fry, D.W., Vincent, P., Nelson, J.M., Elliott, W., Leopold, W.R. Anticancer Res. (1999) [Pubmed]
  36. Pneumonia and mesenteric lymphadenopathy caused by disseminated Penicillium marneffei infection in a cadaveric renal transplant recipient. Chan, Y.H., Wong, K.M., Lee, K.C., Kwok, P.C., Chak, W.L., Choi, K.S., Chau, K.F., Li, C.S. Transplant infectious disease : an official journal of the Transplantation Society. (2004) [Pubmed]
  37. A controlled aquatic ecological life support system (CAELSS) for combined production of fish and higher plant biomass suitable for integration into a lunar or planetary base. Blum, V., Andriske, M., Eichhorn, H., Kreuzberg, K., Schreibman, M.P. Acta astronautica. (1995) [Pubmed]
  38. Clinical and immunologic characteristics and therapeutic interventions in children born to human immunodeficiency virus-infected mothers in southern Taiwan. Lin, H.C., Wang, S.M., Wu, C.S., Chang, F.M., Liu, C.C. Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi. (2005) [Pubmed]
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