The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Informed Consent

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Informed Consent


Psychiatry related information on Informed Consent


High impact information on Informed Consent


Chemical compound and disease context of Informed Consent


Biological context of Informed Consent


Anatomical context of Informed Consent

  • The immunohistochemical distribution of AQP5 was compared in minor salivary gland biopsies obtained from women after informed consent: primary SS (53.2 +/- 14 years old, n = 10), healthy volunteers (46.2 +/- 17 years old, n = 10), patients with sarcoidosis (37 and 48 years old), and patients with non-specific sialoadenitis (54 and 61 years old) [25].
  • METHODS: After taking their informed consent, we determined TFPI concentrations in the plasma of healthy subjects (group I) (n = 15) (average age, 45.1 = 11.8 yr), cirrhotics (group II) (n = 16) (average age, 43.6 +/- 9.8 yr), and cirrhotics with portal vein thrombosis (group III) (n = 12) (average age, 42.6 +/- 10.7 yr) [26].
  • After institutional approval and written informed consent, patients scheduled to undergo coronary artery bypass grafting or valvular surgery were randomly allocated to receive amiodarone (3.4 g over 5 days or 2.2 g over 24 hours) or placebo before surgery [27].
  • Eligibility criteria included measurable disease, performance status 0-2, adequate bone marrow function, creatinine <1.5 mg%, bilirubin <1.5x institutional normal, SGOT/alkaline phosphatase <3x institutional normal, and signed informed consent [28].
  • METHODS: After informed consent and ethics committee approval, 64 patients were randomly allocated to four groups for intercostal nerve block (ropivacaine 2, 5, 7.5 or 10 mg ml-1 at the end of surgery) [29].

Associations of Informed Consent with chemical compounds


Gene context of Informed Consent


Analytical, diagnostic and therapeutic context of Informed Consent


  1. Eosinophilia-myalgia syndrome, L-tryptophan, and informed consent. Mayer, J.W., Knowless, J., Messner, R.P. Lancet (1990) [Pubmed]
  2. N-acetyltransferase 2 polymorphism in patients infected with human immunodeficiency virus. Kaufmann, G.R., Wenk, M., Taeschner, W., Peterli, B., Gyr, K., Meyer, U.A., Haefeli, W.E. Clin. Pharmacol. Ther. (1996) [Pubmed]
  3. The prevalence of men with National Institutes of Health category IV prostatitis and association with serum prostate specific antigen. Carver, B.S., Bozeman, C.B., Williams, B.J., Venable, D.D. J. Urol. (2003) [Pubmed]
  4. Clinical sevoflurane metabolism and disposition. II. The role of cytochrome P450 2E1 in fluoride and hexafluoroisopropanol formation. Kharasch, E.D., Armstrong, A.S., Gunn, K., Artru, A., Cox, K., Karol, M.D. Anesthesiology (1995) [Pubmed]
  5. Hydroxyurea therapy in children severely affected with sickle cell disease. Scott, J.P., Hillery, C.A., Brown, E.R., Misiewicz, V., Labotka, R.J. J. Pediatr. (1996) [Pubmed]
  6. Treatment of chronic posttraumatic stress disorder in combat veterans with citalopram: an open trial. English, B.A., Jewell, M., Jewell, G., Ambrose, S., Davis, L.L. Journal of clinical psychopharmacology. (2006) [Pubmed]
  7. Efficacy of fluvoxamine, paroxetine, and citalopram in the treatment of obsessive-compulsive disorder: a single-blind study. Mundo, E., Bianchi, L., Bellodi, L. Journal of clinical psychopharmacology. (1997) [Pubmed]
  8. Clinical and laboratory effects of discontinuation of lithium prophylaxis. Goodnick, P.J. Acta psychiatrica Scandinavica. (1985) [Pubmed]
  9. Federal regulatory, state statutory, and tort-based problems in research involving informed consent with Alzheimer disease and dementia patients. Sutton, V. Alzheimer disease and associated disorders. (2003) [Pubmed]
  10. Informed consent and BRCA1 testing. Geller, G., Bernhardt, B.A., Helzlsouer, K., Holtzman, N.A., Stefanek, M., Wilcox, P.M. Nat. Genet. (1995) [Pubmed]
  11. Reporting of informed consent and ethics committee approval in clinical trials. Yank, V., Rennie, D. JAMA (2002) [Pubmed]
  12. Genetic testing for susceptibility to adult-onset cancer. The process and content of informed consent. Geller, G., Botkin, J.R., Green, M.J., Press, N., Biesecker, B.B., Wilfond, B., Grana, G., Daly, M.B., Schneider, K., Kahn, M.J. JAMA (1997) [Pubmed]
  13. Randomized double-blind trial of intravenous prochlorperazine for the treatment of acute headache. Jones, J., Sklar, D., Dougherty, J., White, W. JAMA (1989) [Pubmed]
  14. von Willebrand factor interaction with the glycoprotein IIb/IIa complex. Its role in platelet function as demonstrated in patients with congenital afibrinogenemia. De Marco, L., Girolami, A., Zimmerman, T.S., Ruggeri, Z.M. J. Clin. Invest. (1986) [Pubmed]
  15. Intravenous valproate sodium (depacon) aborts migraine rapidly: a preliminary report. Mathew, N.T., Kailasam, J., Meadors, L., Chernyschev, O., Gentry, P. Headache. (2000) [Pubmed]
  16. Monitoring a clinical trial conducted under the Food and Drug Administration regulations allowing a waiver of prospective informed consent: the diaspirin cross-linked hemoglobin traumatic hemorrhagic shock efficacy trial. Lewis, R.J., Berry, D.A., Cryer, H., Fost, N., Krome, R., Washington, G.R., Houghton, J., Blue, J.W., Bechhofer, R., Cook, T., Fisher, M. Annals of emergency medicine. (2001) [Pubmed]
  17. A comparison of treatment with dithranol and calcipotriol on the clinical severity and quality of life in patients with psoriasis. Wall, A.R., Poyner, T.F., Menday, A.P. Br. J. Dermatol. (1998) [Pubmed]
  18. High-dose torasemide, given once daily intravenously for one week, in patients with advanced chronic renal failure. Boesken, W.H., Kult, J. Clin. Nephrol. (1997) [Pubmed]
  19. Cardiac and hemodynamic assessment of patients with cocaine-associated chest pain syndromes. Baumann, B.M., Perrone, J., Hornig, S.E., Shofer, F.S., Hollander, J.E. J. Toxicol. Clin. Toxicol. (2000) [Pubmed]
  20. Prevalence and age-dependence of malignant mutations in the beta-myosin heavy chain and troponin T genes in hypertrophic cardiomyopathy: a comprehensive outpatient perspective. Ackerman, M.J., VanDriest, S.L., Ommen, S.R., Will, M.L., Nishimura, R.A., Tajik, A.J., Gersh, B.J. J. Am. Coll. Cardiol. (2002) [Pubmed]
  21. Aldosterone synthase gene (CYP11B2) C-334T polymorphism, ambulatory blood pressure and nocturnal decline in blood pressure in the general Japanese population: the Ohasama Study. Matsubara, M., Kikuya, M., Ohkubo, T., Metoki, H., Omori, F., Fujiwara, T., Suzuki, M., Michimata, M., Hozawa, A., Katsuya, T., Higaki, J., Tsuji, I., Araki, T., Ogihara, T., Satoh, H., Hisamichi, S., Nagai, K., Kitaoka, H., Imai, Y. J. Hypertens. (2001) [Pubmed]
  22. In vivo percutaneous absorption of hydrocortisone: multiple-application dosing in man. Melendres, J.L., Bucks, D.A., Camel, E., Wester, R.C., Maibach, H.I. Pharm. Res. (1992) [Pubmed]
  23. Confronting the ethical challenges to informed consent in emergency medicine research. Schmidt, T.A., Salo, D., Hughes, J.A., Abbott, J.T., Geiderman, J.M., Johnson, C.X., McClure, K.B., McKay, M.P., Razzak, J.A., Schears, R.M., Solomon, R.C. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine. (2004) [Pubmed]
  24. Drug epidemiology in Italy: methods and ethical issues. The example of psychiatry. Barbui, C. Pharmacoepidemiology and drug safety. (2001) [Pubmed]
  25. Abnormal distribution of aquaporin-5 water channel protein in salivary glands from Sjögren's syndrome patients. Steinfeld, S., Cogan, E., King, L.S., Agre, P., Kiss, R., Delporte, C. Lab. Invest. (2001) [Pubmed]
  26. Tissue factor pathway inhibitor concentrations in cirrhotic patients with and without portal vein thrombosis. Oksüzoğlu, G., Simsek, H., Haznedaroğlu, I.C., Kirazli, S. Am. J. Gastroenterol. (1997) [Pubmed]
  27. An assessment of the safety of short-term amiodarone therapy in cardiac surgical patients with fentanyl-isoflurane anesthesia. White, C.M., Dunn, A., Tsikouris, J., Waberski, W., Felton, K., Freeman-Bosco, L., Giri, S., Kluger, J. Anesth. Analg. (1999) [Pubmed]
  28. Phase II trial of gemcitabine as second-line chemotherapy of uterine leiomyosarcoma: a Gynecologic Oncology Group (GOG) Study. Look, K.Y., Sandler, A., Blessing, J.A., Lucci, J.A., Rose, P.G. Gynecol. Oncol. (2004) [Pubmed]
  29. Plasma concentration of ropivacaine after intercostal blocks for video-assisted thoracic surgery. Behnke, H., Worthmann, F., Cornelissen, J., Kahl, M., Wulf, H. British journal of anaesthesia. (2002) [Pubmed]
  30. Spontaneous regression of localized neuroblastoma detected by mass screening. Yamamoto, K., Hanada, R., Kikuchi, A., Ichikawa, M., Aihara, T., Oguma, E., Moritani, T., Shimanuki, Y., Tanimura, M., Hayashi, Y. J. Clin. Oncol. (1998) [Pubmed]
  31. Natural course of neuroblastoma detected by mass screening: s 5-year prospective study at a single institution. Nishihira, H., Toyoda, Y., Tanaka, Y., Ijiri, R., Aida, N., Takeuchi, M., Ohnuma, K., Kigasawa, H., Kato, K., Nishi, T. J. Clin. Oncol. (2000) [Pubmed]
  32. The effect of dehydroepiandrosterone on lumbar spine bone mineral density in patients with quiescent systemic lupus erythematosus. Hartkamp, A., Geenen, R., Godaert, G.L., Bijl, M., Bijlsma, J.W., Derksen, R.H. Arthritis Rheum. (2004) [Pubmed]
  33. Clinical and economic evaluation of oral ciprofloxacin after an abbreviated course of intravenous antibiotics. Paladino, J.A., Sperry, H.E., Backes, J.M., Gelber, J.A., Serrianne, D.J., Cumbo, T.J., Schentag, J.J. Am. J. Med. (1991) [Pubmed]
  34. Pilocarpine tablets for the treatment of dry mouth and dry eye symptoms in patients with Sjögren syndrome: a randomized, placebo-controlled, fixed-dose, multicenter trial. P92-01 Study Group. Vivino, F.B., Al-Hashimi, I., Khan, Z., LeVeque, F.G., Salisbury, P.L., Tran-Johnson, T.K., Muscoplat, C.C., Trivedi, M., Goldlust, B., Gallagher, S.C. Arch. Intern. Med. (1999) [Pubmed]
  35. Informed consent documents for BRCA1 and BRCA2 screening: how large is the readability gap? Gribble, J.N. Patient education and counseling. (1999) [Pubmed]
  36. Informed consent for BRCA1 and BRCA2 testing: what clinicians should know about the process and content. Miesfeldt, S., Jones, S.M., Cohn, W.F. Journal of the American Medical Women's Association (1972) (2000) [Pubmed]
  37. Association of methylenetetrahydrofolate reductase gene polymorphism with carotid atherosclerosis depending on smoking status in a Japanese general population. Inamoto, N., Katsuya, T., Kokubo, Y., Mannami, T., Asai, T., Baba, S., Ogata, J., Tomoike, H., Ogihara, T. Stroke (2003) [Pubmed]
  38. von Hippel-Lindau disease type 2A in a family with a duplicated 21-base-pair in-frame insertion mutation in the VHL gene. Miyagawa, Y., Nakazawa, M., Noda, Y., Ito, S., Ohguro, H. Graefes Arch. Clin. Exp. Ophthalmol. (2003) [Pubmed]
  39. Mutational analysis of the MRP2 gene and long-term follow-up of Dubin-Johnson syndrome in Japan. Machida, I., Wakusawa, S., Sanae, F., Hayashi, H., Kusakabe, A., Ninomiya, H., Yano, M., Yoshioka, K. J. Gastroenterol. (2005) [Pubmed]
  40. The impact of informed consent on patient interest in prostate-specific antigen screening. Wolf, A.M., Nasser, J.F., Wolf, A.M., Schorling, J.B. Arch. Intern. Med. (1996) [Pubmed]
  41. Multistage ethanol sclerotherapy of soft-tissue arteriovenous malformations: effect on pulmonary arterial pressure. Shin, B.S., Do, Y.S., Lee, B.B., Kim, D.I., Chung, I.S., Cho, H.S., Kim, M.H., Kim, G.S., Kim, C.S., Byun, H.S., Shin, S.W., Park, K.B. Radiology. (2005) [Pubmed]
  42. Intravesical morphine analgesia is not effective after bladder surgery in children: results of a randomied double-blind study. El-Ghoneimi, A., Deffarges, C., Hankard, R., Jean-Eudes, F., Aigrain, Y., Jacqz-Aigrain, E. J. Urol. (2002) [Pubmed]
  43. Randomized trial of parathyroidectomy in mild asymptomatic primary hyperparathyroidism: patient description and effects on the SF-36 health survey. Talpos, G.B., Bone, H.G., Kleerekoper, M., Phillips, E.R., Alam, M., Honasoge, M., Divine, G.W., Rao, D.S. Surgery (2000) [Pubmed]
  44. Reply to invited letter concerning: Informed consent for blood transfusion (J Thorac Cardiovasc Surg 1991;101:563-4). Kolins, J., Kolins, M.D. J. Thorac. Cardiovasc. Surg. (1991) [Pubmed]
WikiGenes - Universities