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Chemical Compound Review

SureCN505501     1-(2,4-dihydroxyphenyl)-3- (3,4...

Synonyms: AG-J-60516, AG-L-65109, MolMap_000005, ANW-43834, CTK7J8903, ...
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Disease relevance of butein


High impact information on butein


Chemical compound and disease context of butein


Biological context of butein


Anatomical context of butein


Associations of butein with other chemical compounds


Gene context of butein


Analytical, diagnostic and therapeutic context of butein


  1. Butein (3,4,2',4'-tetrahydroxychalcone) ameliorates experimental anti-glomerular basement membrane antibody-associated glomerulonephritis (3). Hayashi, K., Nagamatsu, T., Honda, S., Suzuki, Y. Eur. J. Pharmacol. (1996) [Pubmed]
  2. The chalcone butein from Rhus verniciflua shows antifibrogenic activity. Lee, S.H., Nan, J.X., Zhao, Y.Z., Woo, S.W., Park, E.J., Kang, T.H., Seo, G.S., Kim, Y.C., Sohn, D.H. Planta Med. (2003) [Pubmed]
  3. The plant polyphenol butein inhibits testosterone-induced proliferation in breast cancer cells expressing aromatase. Wang, Y., Chan, F.L., Chen, S., Leung, L.K. Life Sci. (2005) [Pubmed]
  4. Inhibition of the efflux of glutathione S-conjugates by plant polyphenols. Zhang, K., Wong, K.P. Biochem. Pharmacol. (1996) [Pubmed]
  5. Inhibition of lipopolysaccharide-induced expression of inducible nitric oxide synthase by butein in RAW 264.7 cells. Lee, S.H., Seo, G.S., Sohn, D.H. Biochem. Biophys. Res. Commun. (2004) [Pubmed]
  6. The chalcone butein from Rhus verniciflua Stokes inhibits clonogenic growth of human breast cancer cells co-cultured with fibroblasts. Samoszuk, M., Tan, J., Chorn, G. BMC complementary and alternative medicine [electronic resource]. (2005) [Pubmed]
  7. Flavonoids inhibit cell growth and induce apoptosis in B16 melanoma 4A5 cells. Iwashita, K., Kobori, M., Yamaki, K., Tsushida, T. Biosci. Biotechnol. Biochem. (2000) [Pubmed]
  8. Cytotoxic effect of butein on human colon adenocarcinoma cell proliferation. Yit, C.C., Das, N.P. Cancer Lett. (1994) [Pubmed]
  9. Butein suppresses myofibroblastic differentiation of rat hepatic stellate cells in primary culture. Woo, S.W., Lee, S.H., Kang, H.C., Park, E.J., Zhao, Y.Z., Kim, Y.C., Sohn, D.H. J. Pharm. Pharmacol. (2003) [Pubmed]
  10. Butein, a plant polyphenol, induces apoptosis concomitant with increased caspase-3 activity, decreased Bcl-2 expression and increased Bax expression in HL-60 cells. Kim, N.Y., Pae, H.O., Oh, G.S., Kang, T.H., Kim, Y.C., Rhew, H.Y., Chung, H.T. Pharmacol. Toxicol. (2001) [Pubmed]
  11. Endothelium-dependent relaxation of rat aorta by butein, a novel cyclic AMP-specific phosphodiesterase inhibitor. Yu, S.M., Cheng, Z.J., Kuo, S.C. Eur. J. Pharmacol. (1995) [Pubmed]
  12. Cytotoxic effect of plant polyphenols and fat-soluble vitamins on malignant human cultured cells. Ramanathan, R., Tan, C.H., Das, N.P. Cancer Lett. (1992) [Pubmed]
  13. Biocatalytic synthesis of butein and sulfuretin by Aspergillus alliaceus. Sanchez-Gonzalez, M., Rosazza, J.P. J. Agric. Food Chem. (2006) [Pubmed]
  14. Extract from Rhus verniciflua Stokes is capable of inhibiting the growth of human lymphoma cells. Lee, J.C., Lee, K.Y., Kim, J., Na, C.S., Jung, N.C., Chung, G.H., Jang, Y.S. Food Chem. Toxicol. (2004) [Pubmed]
  15. Inhibition of epidermal growth factor receptor tyrosine kinase by chalcone derivatives. Yang, E.B., Guo, Y.J., Zhang, K., Chen, Y.Z., Mack, P. Biochim. Biophys. Acta (2001) [Pubmed]
  16. Butein, a specific protein tyrosine kinase inhibitor. Yang, E.B., Zhang, K., Cheng, L.Y., Mack, P. Biochem. Biophys. Res. Commun. (1998) [Pubmed]
  17. Determination of butein in rat serum by high performance liquid chromatography. Lee, H.W., Ji, H.Y., Lee, H.I., Kim, H.K., Sohn, D.H., Kim, Y.C., Chung, H.T., Lee, H.S. Journal of pharmaceutical and biomedical analysis. (2004) [Pubmed]
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