Chemical Compound Review:
AG-G-03279 7-[(1S,3S,4S,5S)-3-[(3S)-3- hydroxyoct-1...
Synonyms:
CTK1H0173
- Prostacyclin and thromboxane changes predating clinical onset of preeclampsia: a multicenter prospective study. Mills, J.L., DerSimonian, R., Raymond, E., Morrow, J.D., Roberts, L.J., Clemens, J.D., Hauth, J.C., Catalano, P., Sibai, B., Curet, L.B., Levine, R.J. JAMA (1999)
- Effects of OKY 046, a thromboxane-synthase inhibitor, on renal function in nonazotemic cirrhotic patients with ascites. Gentilini, P., Laffi, G., Meacci, E., La Villa, G., Cominelli, F., Pinzani, M., Buzzelli, G. Gastroenterology (1988)
- Urinary excretion of degradation products of prostacyclin and thromboxane is increased in patients with gestational choriocarcinoma. Aitokallio-Tallberg, A.M., Jung, J.K., Kim, S.J., Viinikka, L.U., Ylikorkala, R.O. Cancer Res. (1991)
- Inhibition of thromboxane biosynthesis and platelet function by simvastatin in type IIa hypercholesterolemia. Notarbartolo, A., Davì, G., Averna, M., Barbagallo, C.M., Ganci, A., Giammarresi, C., La Placa, F.P., Patrono, C. Arterioscler. Thromb. Vasc. Biol. (1995)
- Effect of conjugated estrogens on platelet function and prostacyclin generation in CRF. Heistinger, M., Stockenhuber, F., Schneider, B., Pabinger, I., Brenner, B., Wagner, B., Balcke, P., Lechner, K., Kyrle, P.A. Kidney Int. (1990)
- Mechanism of platelet inhibition by nitric oxide: in vivo phosphorylation of thromboxane receptor by cyclic GMP-dependent protein kinase. Wang, G.R., Zhu, Y., Halushka, P.V., Lincoln, T.M., Mendelsohn, M.E. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Monosodium urate microcrystals induce cyclooxygenase-2 in human monocytes. Pouliot, M., James, M.J., McColl, S.R., Naccache, P.H., Cleland, L.G. Blood (1998)
- Thromboxane and prostacyclin synthesis in experimental pancreas transplantation. Changes in parenchymal and vascular prostanoids. Johnson, B.F., Thomas, G., Wiley, K.N., Greaves, M., Preston, F.E., Fox, M., Raftery, A.T. Transplantation (1993)
- Effects of aerosol administration of a thromboxane receptor antagonist (S-1452) on experimental asthma in guinea pigs. Saito, M., Fujimura, M., Mizuhashi, K., Shintani, H., Matsuda, T. Allergy (1994)
- Effects of thromboxane synthetase inhibitor (RS-5186) on experimentally-induced cerebral vasospasm. Takeuchi, H., Tanabe, M., Okamoto, H., Yamazaki, M. Neurol. Res. (1999)
- Role of prostaglandins and thromboxane in the control of renal hemodynamics in experimental liver cirrhosis. Leehey, D.J., Uckerman, M.T., Rahman, M.A. J. Lab. Clin. Med. (1989)
- Effect of leukotriene and thromboxane antagonist on propranolol-induced bronchoconstriction. Fujimura, M., Abo, M., Kamio, Y., Myou, S., Ishiura, Y., Hashimoto, T., Matsuda, T. Am. J. Respir. Crit. Care Med. (1999)
- New trends in thromboxane and prostacyclin modulators. Dogné, J.M., de Leval, X., Delarge, J., David, J.L., Masereel, B. Current medicinal chemistry. (2000)
- Renal prostacyclin biosynthesis is reduced in children with hemolytic-uremic syndrome in the context of systemic platelet activation. Noris, M., Benigni, A., Siegler, R., Gaspari, F., Casiraghi, F., Mancini, M.L., Remuzzi, G. Am. J. Kidney Dis. (1992)
- Reduction of prostacyclin synthesis as a possible cause of transient flow reduction in a partially constricted canine coronary artery. Tada, M., Esumi, K., Yamagishi, M., Kuzuya, T., Matsuda, H., Abe, H., Uchida, Y., Murao, S. J. Mol. Cell. Cardiol. (1984)
- Cultured endothelial cells increase their capacity to synthesize prostacyclin following the formation of a contact inhibited cell monolayer. Eldor, A., Vlodavsky, I., Hy-Am, E., Atzmon, R., Weksler, B.B., Raz, A., Fuks, Z. J. Cell. Physiol. (1983)
- Augmented contraction of the human isolated coronary artery by sumatriptan: a possible role for endogenous thromboxane. Maassen VanDenBrink, A., Bax, W.A., Ferrari, M.D., Zijlstra, F.J., Bos, E., Saxena, P.R. Br. J. Pharmacol. (1996)
- Effects of isocarbacyclin, a stable prostacyclin analogue, on monkey isolated cerebral and peripheral arteries. Kawai, Y., Ohhashi, T. Br. J. Pharmacol. (1994)
- Reduction in myocardial neutrophil accumulation and infarct size following administration of thromboxane inhibitor U-63,557A. Wargovich, T.J., Mehta, J., Nichols, W.W., Ward, M.B., Lawson, D., Franzini, D., Conti, C.R. Am. Heart J. (1987)
- Estrogen stimulation of COX-2-derived PGI2 confers atheroprotection. Shah, B.H. Trends Endocrinol. Metab. (2005)
- Regulatory interactions between inducible nitric oxide synthase and eicosanoids in glomerular immune injury. Lianos, E.A., Guglielmi, K., Sharma, M. Kidney Int. (1998)
- Implication of thromboxane in frusemide diuresis in rats. Melki, T.S., Foegh, M.L., Ramwell, P.W. Clin. Sci. (1986)
- Induction of cytosolic phospholipase A2 and prostaglandin H2 synthase-2 by lipopolysaccharide in human polymorphonuclear leukocytes. Zaitsu, M., Hamasaki, Y., Matsuo, M., Miyazaki, M., Hayasaki, R., Muro, E., Yamamoto, S., Kobayashi, I., Ichimaru, T., Miyazaki, S. Eur. J. Haematol. (1999)
- Differential expression of thromboxane A synthase and prostaglandin H synthase in megakaryocytic cell line. Matijevic-Aleksic, N., Sanduja, S.K., Wang, L.H., Wu, K.K. Biochim. Biophys. Acta (1995)
- Mechanisms mediating the vasoactive effects of the B1 receptors of bradykinin. Duka, I., Duka, A., Kintsurashvili, E., Johns, C., Gavras, I., Gavras, H. Hypertension (2003)
- Effects of meloxicam on platelet function in healthy adults: a randomized, double-blind, placebo-controlled trial. Rinder, H.M., Tracey, J.B., Souhrada, M., Wang, C., Gagnier, R.P., Wood, C.C. Journal of clinical pharmacology. (2002)
- Thromboxane synthase inhibitor, UK 38485, prevents renal injury in the rabbit isolated perfused kidney exposed to cold ischemia. Kuzu, M.A., Köksoy, C., Alaçayir, I., Yazar, O., Kuterdem, E. Transplantation (1995)
- Urinary excretion of prostacyclin and thromboxane degradation products in patients with ovarian malignancy: effect of cytostatic treatment. Aitokallio-Tallberg, A., Viinikka, L., Ylikorkala, O. Br. J. Cancer (1989)
- Beneficial effects of iloprost cardioplegia in ischemic arrest in isolated working rat heart. Feng, J., Wu, G., Tang, S., Chahine, R., Lamontagne, D. Prostaglandins Leukot. Essent. Fatty Acids (1996)
- Pharmacological studies on the TXA2 synthetase inhibitor (E)-3-[p-(1H-imidazol-1-ylmethyl)phenyl]-2-propenoic acid (OKY-046). Hiraku, S., Taniguchi, K., Wakitani, K., Omawari, N., Kira, H., Miyamoto, T., Okegawa, T., Kawasaki, A., Ujiie, A. Jpn. J. Pharmacol. (1986)