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Chemical Compound Review

Conjugated estrogens     sodium(8S,9S,13S,14S)-13- methyl-17-oxo-3...

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Disease relevance of Estrone hydrogen sulfate


Psychiatry related information on Estrone hydrogen sulfate


High impact information on Estrone hydrogen sulfate


Chemical compound and disease context of Estrone hydrogen sulfate


Biological context of Estrone hydrogen sulfate


Anatomical context of Estrone hydrogen sulfate


Associations of Estrone hydrogen sulfate with other chemical compounds


Gene context of Estrone hydrogen sulfate

  • Oral norethisterone plus conjugated estrogens increased free IGF-I and IGFBP-1 concentrations but did not change IGF-I concentrations [30].
  • In the women treated with oral conjugated estrogens, an increase in SHBG (p < 0.001), a decrease in IGF-1 (p < 0.001) and an increase in growth hormone (p < 0.05) serum levels were observed [31].
  • Two conjugated estrogens that are not Mrp2 substrates did not produce this effect [32].
  • In contrast, eight weeks of oral conjugated estrogens caused a more than twofold increase in CRP and a significant reduction in IGF-1 (p < 0.01) in the same women [33].
  • During incremental exercise, catecholamines, PRL, E2, unconjugated and conjugated estrogens, 4-OHE, and 4-MeOE always increased (the increases in 4-OHE during exercise were more pronounced before training, contrary to the 4-MeOE being most increased after training) [34].

Analytical, diagnostic and therapeutic context of Estrone hydrogen sulfate


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  17. Prevention of early postmenopausal bone loss using low doses of conjugated estrogens and the non-hormonal, bone-active drug ipriflavone. Agnusdei, D., Gennari, C., Bufalino, L. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. (1995) [Pubmed]
  18. Conjugated estrogens acutely abolish abnormal cold-induced coronary vasoconstriction in male cardiac allografts. Reis, S.E., Bhoopalam, V., Zell, K.A., Counihan, P.J., Smith, A.J., Pham, S., Murali, S. Circulation (1998) [Pubmed]
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  21. The effect of hormone replacement therapy on body composition, body fat distribution, and insulin sensitivity in menopausal women: a randomized, double-blind, placebo-controlled trial. Sites, C.K., L'Hommedieu, G.D., Toth, M.J., Brochu, M., Cooper, B.C., Fairhurst, P.A. J. Clin. Endocrinol. Metab. (2005) [Pubmed]
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  26. Pulse amplitude and frequency modulation of parathyroid hormone in early postmenopausal women before and on hormone replacement therapy. Harms, H.M., Neubauer, O., Kayser, C., Wüstermann, P.R., Horn, R., Brosa, U., Schlinke, E., Külpmann, W.R., von zur Mühlen, A., Hesch, R.D. J. Clin. Endocrinol. Metab. (1994) [Pubmed]
  27. The effects of transdermal estradiol and oral conjugated estrogens on haemostasis variables. Kroon, U.B., Silfverstolpe, G., Tengborn, L. Thromb. Haemost. (1994) [Pubmed]
  28. Effect of conjugated estrogens on platelet function and prostacyclin generation in CRF. Heistinger, M., Stockenhuber, F., Schneider, B., Pabinger, I., Brenner, B., Wagner, B., Balcke, P., Lechner, K., Kyrle, P.A. Kidney Int. (1990) [Pubmed]
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  31. Differential effects of oral conjugated estrogens and transdermal estradiol on insulin-like growth factor 1, growth hormone and sex hormone binding globulin serum levels. Campagnoli, C., Biglia, N., Altare, F., Lanza, M.G., Lesca, L., Cantamessa, C., Peris, C., Fiorucci, G.C., Sismondi, P. Gynecol. Endocrinol. (1993) [Pubmed]
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  34. 4-Hydroxycatecholestrogen metabolism responses to exercise and training: possible implications for menstrual cycle irregularities and breast cancer. De Crée, C., Van Kranenburg, G., Geurten, P., Fujimori, Y., Keizer, H.A. Fertil. Steril. (1997) [Pubmed]
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