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Chemical Compound Review

CHEBI:30703     disulfanylidenemolybdenum; sulfanide

Synonyms: [MoS4](2-), tetrathiomolybdate(2-), Tetrathioxomolybdate(2-), tetrasulfidomolybdate(VI), tetrasulfidomolybdate(2-), ...
 
 
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Disease relevance of Tetrathiomolybdate

 

Psychiatry related information on Tetrathiomolybdate

 

High impact information on Tetrathiomolybdate

 

Chemical compound and disease context of Tetrathiomolybdate

 

Biological context of Tetrathiomolybdate

 

Anatomical context of Tetrathiomolybdate

 

Associations of Tetrathiomolybdate with other chemical compounds

 

Gene context of Tetrathiomolybdate

 

Analytical, diagnostic and therapeutic context of Tetrathiomolybdate

References

  1. Copper deficiency induced by tetrathiomolybdate suppresses tumor growth and angiogenesis. Pan, Q., Kleer, C.G., van Golen, K.L., Irani, J., Bottema, K.M., Bias, C., De Carvalho, M., Mesri, E.A., Robins, D.M., Dick, R.D., Brewer, G.J., Merajver, S.D. Cancer Res. (2002) [Pubmed]
  2. Inhibition of iron-molybdenum cofactor binding to component I of nitrogenase. Shah, V.K., Ugalde, R.A., Imperial, J., Brill, W.J. J. Biol. Chem. (1985) [Pubmed]
  3. Wilson disease: genetic basis of copper toxicity and natural history. Schilsky, M.L. Semin. Liver Dis. (1996) [Pubmed]
  4. Phase II trial of tetrathiomolybdate in patients with advanced kidney cancer. Redman, B.G., Esper, P., Pan, Q., Dunn, R.L., Hussain, H.K., Chenevert, T., Brewer, G.J., Merajver, S.D. Clin. Cancer Res. (2003) [Pubmed]
  5. Copper binding by tetrathiomolybdate attenuates angiogenesis and tumor cell proliferation through the inhibition of superoxide dismutase 1. Juarez, J.C., Betancourt, O., Pirie-Shepherd, S.R., Guan, X., Price, M.L., Shaw, D.E., Mazar, A.P., Doñate, F. Clin. Cancer Res. (2006) [Pubmed]
  6. Combination tetrathiomolybdate and radiation therapy in a mouse model of head and neck squamous cell carcinoma. Khan, M.K., Mamou, F., Schipper, M.J., May, K.S., Kwitny, A., Warnat, A., Bolton, B., Nair, B.M., Kariapper, M.S., Miller, M., Brewer, G., Normolle, D., Merajver, S.D., Teknos, T.N. Arch. Otolaryngol. Head Neck Surg. (2006) [Pubmed]
  7. Copper chelation represses the vascular response to injury. Mandinov, L., Mandinova, A., Kyurkchiev, S., Kyurkchiev, D., Kehayov, I., Kolev, V., Soldi, R., Bagala, C., de Muinck, E.D., Lindner, V., Post, M.J., Simons, M., Bellum, S., Prudovsky, I., Maciag, T. Proc. Natl. Acad. Sci. U.S.A. (2003) [Pubmed]
  8. Tetrathiomolybdate causes formation of hepatic copper-molybdenum clusters in an animal model of Wilson's disease. George, G.N., Pickering, I.J., Harris, H.H., Gailer, J., Klein, D., Lichtmannegger, J., Summer, K.H. J. Am. Chem. Soc. (2003) [Pubmed]
  9. Treatment of Wilson disease with ammonium tetrathiomolybdate: IV. Comparison of tetrathiomolybdate and trientine in a double-blind study of treatment of the neurologic presentation of Wilson disease. Brewer, G.J., Askari, F., Lorincz, M.T., Carlson, M., Schilsky, M., Kluin, K.J., Hedera, P., Moretti, P., Fink, J.K., Tankanow, R., Dick, R.B., Sitterly, J. Arch. Neurol. (2006) [Pubmed]
  10. Anticopper therapy against cancer and diseases of inflammation and fibrosis. Brewer, G.J. Drug Discov. Today (2005) [Pubmed]
  11. Elicitation of thiomolybdates from the iron-molybdenum cofactor of nitrogenase. Comparison with synthetic Fe-Mo-S complexes. Newton, W.E., Gheller, S.F., Hedman, B., Hodgson, K.O., Lough, S.M., McDonald, J.W. Eur. J. Biochem. (1986) [Pubmed]
  12. Inhibition of key cytokines by tetrathiomolybdate in the bleomycin model of pulmonary fibrosis. Brewer, G.J., Dick, R., Ullenbruch, M.R., Jin, H., Phan, S.H. J. Inorg. Biochem. (2004) [Pubmed]
  13. Tetrathiomolybdate protects against cardiac damage by doxorubicin in mice. Hou, G., Dick, R., Abrams, G.D., Brewer, G.J. J. Lab. Clin. Med. (2005) [Pubmed]
  14. Practical recommendations and new therapies for Wilson's disease. Brewer, G.J. Drugs (1995) [Pubmed]
  15. The effect of tetrathiomolybdate on cytokine expression, angiogenesis, and tumor growth in squamous cell carcinoma of the head and neck. Teknos, T.N., Islam, M., Arenberg, D.A., Pan, Q., Carskadon, S.L., Abarbanell, A.M., Marcus, B., Paul, S., Vandenberg, C.D., Carron, M., Nor, J.E., Merajver, S.D. Arch. Otolaryngol. Head Neck Surg. (2005) [Pubmed]
  16. The effects of ammonium tetrathiomolybdate intake on tissue copper and molybdenum in pregnant ewes and lambs. Kincaid, R.L., White, C.L. J. Anim. Sci. (1988) [Pubmed]
  17. The effects of tetrathiomolybdate (TTM, NSC-714598) and copper supplementation on fertility and early embryonic development in rats. Lyubimov, A.V., Smith, J.A., Rousselle, S.D., Mercieca, M.D., Tomaszewski, J.E., Smith, A.C., Levine, B.S. Reprod. Toxicol. (2004) [Pubmed]
  18. Molybdenum and copper kinetics after tetrathiomolybdate injection in LEC rats: specific role of serum albumin. Suzuki, K.T., Ogra, Y., Ohmichi, M. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). (1995) [Pubmed]
  19. Comparative effects of metal chelating agents on the neuronal cytotoxicity induced by copper (Cu+2), iron (Fe+3) and zinc in the hippocampus. Armstrong, C., Leong, W., Lees, G.J. Brain Res. (2001) [Pubmed]
  20. Effect of copper and thiomolybdates on bovine theca cell differentiation in vitro. Kendall, N.R., Marsters, P., Guo, L., Scaramuzzi, R.J., Campbell, B.K. J. Endocrinol. (2006) [Pubmed]
  21. Subcellular distribution of copper in the kidneys of normal, copper-poisoned, and thiomolybdate-treated sheep. Gooneratne, S.R., Howell, J.M., Gawthorne, J.M., Kumaratilake, J.S. J. Inorg. Biochem. (1989) [Pubmed]
  22. The effect of tetrathiomolybdate on the metabolism of copper by hepatocytes and fibroblasts. McArdle, H.J., Gross, S.M., Vogel, H.M., Ackland, M.L., Danks, D.M. Biological trace element research. (1989) [Pubmed]
  23. Differential adsorption of molybdate and tetrathiomolybdate on pyrite (FeS2). Bostick, B.C., Fendorf, S., Helz, G.R. Environ. Sci. Technol. (2003) [Pubmed]
  24. The behaviour of thiomolybdates in in vitro systems. Weber, K.M., Leaver, D.D., Wedd, A.G. Br. J. Nutr. (1979) [Pubmed]
  25. Adsorption of molybdate and tetrathiomolybdate onto pyrite and goethite: effect of pH and competitive anions. Xu, N., Christodoulatos, C., Braida, W. Chemosphere (2006) [Pubmed]
  26. Tetrathiomolybdate therapy protects against concanavalin a and carbon tetrachloride hepatic damage in mice. Askari, F.K., Dick, R., Mao, M., Brewer, G.J. Exp. Biol. Med. (Maywood) (2004) [Pubmed]
  27. Toward a core nutraceutical program for cancer management. McCarty, M.F., Block, K.I. Integrative cancer therapies. (2006) [Pubmed]
  28. Copper induces the assembly of a multiprotein aggregate implicated in the release of fibroblast growth factor 1 in response to stress. Landriscina, M., Bagalá, C., Mandinova, A., Soldi, R., Micucci, I., Bellum, S., Prudovsky, I., Maciag, T. J. Biol. Chem. (2001) [Pubmed]
  29. Tetrathiomolybdate blocks bFGF- but not VEGF-induced incipient angiogenesis in vitro. Mamou, F., May, K.S., Schipper, M.J., Gill, N., Kariapper, M.S., Nair, B.M., Brewer, G., Normolle, D., Khan, M.K. Anticancer Res. (2006) [Pubmed]
  30. Multifocal angiostatic therapy: an update. McCarty, M.F., Block, K.I. Integrative cancer therapies. (2005) [Pubmed]
  31. Iron and copper requirements for proliferation and differentiation of a human promyelocytic leukemia cell line (HL-60). Sergeant, S., Johnson, W.T. J. Cell. Physiol. (1995) [Pubmed]
  32. Tetrathiomolybdate is effective in a mouse model of arthritis. McCubbin, M.D., Hou, G., Abrams, G.D., Dick, R., Zhang, Z., Brewer, G.J. J. Rheumatol. (2006) [Pubmed]
  33. Intravenous administration of thiomolybdate for the prevention and treatment of chronic copper poisoning in sheep. Gooneratne, S.R., Howell, J.M., Gawthorne, J.M. Br. J. Nutr. (1981) [Pubmed]
  34. Immunocytochemical detection of metallothionein (MT1 and MT2) in copper-enhanced sheep brains. Dincer, Z., Haywood, S., Jasani, B. J. Comp. Pathol. (1999) [Pubmed]
  35. A convenient method for the treatment of chronic copper poisoning in sheep using subcutaneous ammonium tetrathiomolybdate. Humphries, W.R., Morrice, P.C., Bremner, I. Vet. Rec. (1988) [Pubmed]
 
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