The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

aesculin     7-hydroxy-6- [(2S,3R,4S,5S,6R)-3,4,5...

Synonyms: Esculine, Bicolorin, Crataegin, Escosyl, Esculin, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of aesculin


High impact information on aesculin


Chemical compound and disease context of aesculin


Biological context of aesculin


Anatomical context of aesculin

  • Histomorphometric evaluation and polychrome sequential labeling showed a more progressed bone matrix formation in the cylindrical cage group than in both other groups [20].
  • It lacks a cell wall; ferments glucose, mannose, lactose and sucrose; does not produce 'film and spots'; does not hydrolyse arginine, aesculin or urea; is sensitive to digitonin; and lacks phosphatase activity [21].
  • The polychrome-stained equine synovial fluid smears were found to provide information supportive of clinical, radiographic and prognostic data [22].
  • Phospholipid concentrations were increased in rats exposed to 1.1 mg/m(3) and above (elevated levels of lipid material in alveolar macrophages demonstrated by polychrome stain) and 3.3 mg/m(3) and above (increased intracellular ACPh activity and intracellular phospholipids) [23].
  • In addition, all the ECP samples showed caseinase, gelatinase, amylase, lipase and phospholipase activities, hydrolysed esculin and displayed hemolytic activities for trout, salmon, sheep and human erythrocytes [24].

Associations of aesculin with other chemical compounds


Gene context of aesculin

  • It was hypothesized that antitermination is the regulatory mechanism that is responsible for the control of the bglP gene expression, which encodes an esculin-specific PTS enzyme II [30].
  • Succinivibrio spp. will grow in bile, will not hydrolyze esculin or starch, and do not produce indol, catalase, lecithinase, lipase, or hemolysis [31].
  • It was calculated that the activation energy for aesculin hydrolysis was 49.4kJ/mol [28].
  • Histomorphological, -morphometrical, and polychrome sequential labeling analyses demonstrated greater progression of callus formation in the BMP-2 groups than in any other group [32].
  • In the present study, we implanted untreated, alkaline-etched and FN-coated Ecopore cylinders into critical size defects of rabbit femora and applied pulsed polychrome sequence staining [33].

Analytical, diagnostic and therapeutic context of aesculin


  1. Toward functional genomics in bacteria: analysis of gene expression in Escherichia coli from a bacterial artificial chromosome library of Bacillus cereus. Rondon, M.R., Raffel, S.J., Goodman, R.M., Handelsman, J. Proc. Natl. Acad. Sci. U.S.A. (1999) [Pubmed]
  2. Esculin hydrolysis by Enterobacteriaceae. Edberg, S.C., Pittman, S., Singer, J.M. J. Clin. Microbiol. (1977) [Pubmed]
  3. Highly selective medium for isolation of Listeria monocytogenes from food. al-Zoreky, N., Sandine, W.E. Appl. Environ. Microbiol. (1990) [Pubmed]
  4. Lack of constitutive beta-glucosidase (esculinase) in the genus Fusobacterium. Edberg, S.C., Bell, S.R. J. Clin. Microbiol. (1985) [Pubmed]
  5. Esculin hydrolysis reaction by Escherichia coli. Miskin, A., Edberg, S.C. J. Clin. Microbiol. (1978) [Pubmed]
  6. Arabidopsis Sucrose Transporter AtSUC9. High-Affinity Transport Activity, Intragenic Control of Expression, and Early Flowering Mutant Phenotype. Sivitz, A.B., Reinders, A., Johnson, M.E., Krentz, A.D., Grof, C.P., Perroux, J.M., Ward, J.M. Plant Physiol. (2007) [Pubmed]
  7. Polychrome labeling of bone with seven different fluorochromes: enhancing fluorochrome discrimination by spectral image analysis. Pautke, C., Vogt, S., Tischer, T., Wexel, G., Deppe, H., Milz, S., Schieker, M., Kolk, A. Bone (2005) [Pubmed]
  8. First description of Curtobacterium spp. isolated from human clinical specimens. Funke, G., Aravena-Roman, M., Frodl, R. J. Clin. Microbiol. (2005) [Pubmed]
  9. DNA relatedness, phenotypic characteristics, and antimicrobial susceptibilities of Globicatella sanguinis strains. Shewmaker, P.L., Steigerwalt, A.G., Shealey, L., Weyant, R., Facklam, R.R. J. Clin. Microbiol. (2001) [Pubmed]
  10. Genetic and biochemical diversity among isolates of Paenibacillus alvei cultured from Australian honeybee (Apis mellifera) colonies. Djordjevic, S.P., Forbes, W.A., Smith, L.A., Hornitzky, M.A. Appl. Environ. Microbiol. (2000) [Pubmed]
  11. Comparison of spot esculin hydrolysis with the PathoTec strip test for rapid differentiation of anaerobic bacteria. Qadri, S.M., Johnson, S., Smith, J.C., Zubairi, S., Gillum, R.L. J. Clin. Microbiol. (1981) [Pubmed]
  12. New medium for selection and presumptive identification of the Bacteroides fragilis group. Livingston, S.J., Kominos, S.D., Yee, R.B. J. Clin. Microbiol. (1978) [Pubmed]
  13. Classification of Proteus vulgaris biogroup 3 with recognition of Proteus hauseri sp. nov., nom. rev. and unnamed Proteus genomospecies 4, 5 and 6. O'Hara, C.M., Brenner, F.W., Steigerwalt, A.G., Hill, B.C., Holmes, B., Grimont, P.A., Hawkey, P.M., Penner, J.L., Miller, J.M., Brenner, D.J. Int. J. Syst. Evol. Microbiol. (2000) [Pubmed]
  14. Direct antimicrobial susceptibility testing in bacteriuria. Brönnestam, R. APMIS (1999) [Pubmed]
  15. Clinical significance of virulence-related assay of Yersinia species. Noble, M.A., Barteluk, R.L., Freeman, H.J., Subramaniam, R., Hudson, J.B. J. Clin. Microbiol. (1987) [Pubmed]
  16. Identification of gram-positive coccal and coccobacillary vancomycin-resistant bacteria. Facklam, R., Hollis, D., Collins, M.D. J. Clin. Microbiol. (1989) [Pubmed]
  17. The LicT protein acts as both a positive and a negative regulator of loci within the bgl regulon of Streptococcus mutans. Cote, C.K., Honeyman, A.L. Microbiology (Reading, Engl.) (2003) [Pubmed]
  18. Suppression of 8-oxo-2'-deoxyguanosine formation and carcinogenesis induced by N-nitrosobis (2-oxopropyl)amine in hamsters by esculetin and esculin. Kaneko, T., Tahara, S., Takabayashi, F., Harada, N. Free Radic. Res. (2004) [Pubmed]
  19. Effects of baicalein and esculetin on transduction signals and growth factors expression in T-lymphoid leukemia cells. Huang, H.C., Hsieh, L.M., Chen, H.W., Lin, Y.S., Chen, J.S. Eur. J. Pharmacol. (1994) [Pubmed]
  20. Influence of cage design on interbody fusion in a sheep cervical spine model. Kandziora, F., Schollmeier, G., Scholz, M., Schaefer, J., Scholz, A., Schmidmaier, G., Schröder, R., Bail, H., Duda, G., Mittlmeier, T., Haas, N.P. J. Neurosurg. (2002) [Pubmed]
  21. Mycoplasma testudineum sp. nov., from a desert tortoise (Gopherus agassizii) with upper respiratory tract disease. Brown, D.R., Merritt, J.L., Jacobson, E.R., Klein, P.A., Tully, J.G., Brown, M.B. Int. J. Syst. Evol. Microbiol. (2004) [Pubmed]
  22. Cytology of polychrome-stained equine synovial fluid smears. Comparison with clinical findings, histologic specimens, Wright-Giemsa-stained smears and outcome. Freeman, K.P., Todhunter, R., Lust, G., Erb, H., Rakestraw, P., Slusher, S.H., Carroll, B. Acta Cytol. (1991) [Pubmed]
  23. Two-week inhalation toxicity of polymeric diphenylmethane-4, 4'-diisocyanate (PMDI) in rats: analysis of biochemical and morphological markers of early pulmonary response. Pauluhn, J., Emura, M., Mohr, U., Popp, A., Rosenbruch, M. Inhalation toxicology. (1999) [Pubmed]
  24. Pathological activities of Yersinia ruckeri, the enteric redmouth (ERM) bacterium. Romalde, J.L., Toranzo, A.E. FEMS Microbiol. Lett. (1993) [Pubmed]
  25. Characterization of bacteroides melaninogenicus. Harding, G.K., Sutter, V.L., Finegold, S.M., Bricknell, K.S. J. Clin. Microbiol. (1976) [Pubmed]
  26. Identification of Streptococcus suis isolated from swine: proposal for biochemical parameters. Tarradas, C., Arenas, A., Maldonado, A., Luque, I., Miranda, A., Perea, A. J. Clin. Microbiol. (1994) [Pubmed]
  27. Enterobacter hormaechei, a new species of the family Enterobacteriaceae formerly known as enteric group 75. O'Hara, C.M., Steigerwalt, A.G., Hill, B.C., Farmer, J.J., Fanning, G.R., Brenner, D.J. J. Clin. Microbiol. (1989) [Pubmed]
  28. Determination of the hydrolysis rate constants and activation energy of aesculin with capillary electrophoresis end-column amperometric detection. Zhang, L., Tong, P., Chen, G. Journal of chromatography. A. (2005) [Pubmed]
  29. Enterobacter turicensis sp. nov. and Enterobacter helveticus sp. nov., isolated from fruit powder. Stephan, R., Van Trappen, S., Cleenwerck, I., Vancanneyt, M., De Vos, P., Lehner, A. Int. J. Syst. Evol. Microbiol. (2007) [Pubmed]
  30. Transcriptional analysis of the bglP gene from Streptococcus mutans. Cote, C.K., Honeyman, A.L. BMC Microbiol. (2006) [Pubmed]
  31. Bacteremia due to Succinivibrio dextrinosolvens. Report of a case. Southern, P.M. Am. J. Clin. Pathol. (1975) [Pubmed]
  32. Bone morphogenetic protein-2 application by a poly(D,L-lactide)-coated interbody cage: in vivo results of a new carrier for growth factors. Kandziora, F., Bail, H., Schmidmaier, G., Schollmeier, G., Scholz, M., Knispel, C., Hiller, T., Pflugmacher, R., Mittlmeier, T., Raschke, M., Haas, N.P. J. Neurosurg. (2002) [Pubmed]
  33. The effect of surface modification of a porous TiO2/perlite composite on the ingrowth of bone tissue in vivo. Erli, H.J., Rüger, M., Ragoss, C., Jahnen-Dechent, W., Hollander, D.A., Paar, O., von Walter, M. Biomaterials (2006) [Pubmed]
  34. Analysis of illicit drugs in human urine by micellar electrokinetic capillary chromatography with on-column fast scanning polychrome absorption detection. Wernly, P., Thormann, W. Anal. Chem. (1991) [Pubmed]
  35. Detection of clinically relevant genotypes of vancomycin-resistant enterococci in nosocomial surveillance specimens by PCR. Jayaratne, P., Rutherford, C. J. Clin. Microbiol. (1999) [Pubmed]
  36. Convenient selective differential broth for isolation of vancomycin-resistant enterococcus from fecal material. Novicki, T.J., Schapiro, J.M., Ulness, B.K., Sebeste, A., Busse-Johnston, L., Swanson, K.M., Swanzy, S.R., Leisenring, W., Limaye, A.P. J. Clin. Microbiol. (2004) [Pubmed]
  37. Streptococcus infantarius sp. nov., Streptococcus infantarius subsp. infantarius subsp. nov. and Streptococcus infantarius subsp. coli subsp. nov., isolated from humans and food. Schlegel, L., Grimont, F., Collins, M.D., Régnault, B., Grimont, P.A., Bouvet, A. Int. J. Syst. Evol. Microbiol. (2000) [Pubmed]
WikiGenes - Universities