Gene Review:
Ctrl - chymotrypsin-like
Mus musculus
Synonyms:
0910001G08Rik, 1810004D15Rik, AV005227, Ctra-1, Ctra1, ...
- Delayed expulsion of the nematode Trichinella spiralis in mice lacking the mucosal mast cell-specific granule chymase, mouse mast cell protease-1. Knight, P.A., Wright, S.H., Lawrence, C.E., Paterson, Y.Y., Miller, H.R. J. Exp. Med. (2000)
- Mechanism of attenuation of skeletal muscle protein catabolism in cancer cachexia by eicosapentaenoic acid. Whitehouse, A.S., Smith, H.J., Drake, J.L., Tisdale, M.J. Cancer Res. (2001)
- Myostatin gene deletion prevents glucocorticoid-induced muscle atrophy. Gilson, H., Schakman, O., Combaret, L., Lause, P., Grobet, L., Attaix, D., Ketelslegers, J.M., Thissen, J.P. Endocrinology (2007)
- Determinants of mouse hepatitis virus 3C-like proteinase activity. Lu, Y., Denison, M.R. Virology (1997)
- Alphavirus replication in cultured cells and infected animals is inhibited by antiproteinase agents. Zhirnov, O.P., Ovcharenko, A.V., Melnikova, E.E., Bukrinskaya, A.G., Gaidamovich SYa, n.u.l.l. Antiviral Res. (1986)
- Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin. Fenteany, G., Standaert, R.F., Lane, W.S., Choi, S., Corey, E.J., Schreiber, S.L. Science (1995)
- Interferon gamma stimulation modulates the proteolytic activity and cleavage site preference of 20S mouse proteasomes. Boes, B., Hengel, H., Ruppert, T., Multhaup, G., Koszinowski, U.H., Kloetzel, P.M. J. Exp. Med. (1994)
- Probiotics inhibit nuclear factor-kappaB and induce heat shock proteins in colonic epithelial cells through proteasome inhibition. Petrof, E.O., Kojima, K., Ropeleski, M.J., Musch, M.W., Tao, Y., De Simone, C., Chang, E.B. Gastroenterology (2004)
- Inactivation of interferons: halomethyl ketone derivatives of phenylalanine as affinity labels. McCray, J.W., Weil, R. Proc. Natl. Acad. Sci. U.S.A. (1982)
- Induction of various androgen-dependent esteroproteases (trypsin-like and chymotrypsin-like enzymes) by tri-iodo-L-thyronine in the submandibular glands of female mice and mice with testicular feminization. Hosoi, K., Kida, T., Ueha, T. J. Biochem. (1981)
- Genetic and biochemical characterization of a new chymotrypsin isozyme of the house mouse, CTRA-1. von Deimling, O.H., Gröning, J., Gaa, A. Biochem. Genet. (1991)
- Deletion of Smad2 in mouse liver reveals novel functions in hepatocyte growth and differentiation. Ju, W., Ogawa, A., Heyer, J., Nierhof, D., Yu, L., Kucherlapati, R., Shafritz, D.A., Böttinger, E.P. Mol. Cell. Biol. (2006)
- Thrombin is inactivated by mast cell secretory granule chymase. Pejler, G., Karlström, A. J. Biol. Chem. (1993)
- Pathways for degradation of the catalytic subunit of cAMP-dependent protein kinase differ in wild-type and kinase-negative S49 mouse lymphoma cells. Lee, S.L., Steinberg, R.A. J. Biol. Chem. (1996)
- Complete genomic sequence and phylogenetic analysis of the lactate dehydrogenase-elevating virus (LDV). Godeny, E.K., Chen, L., Kumar, S.N., Methven, S.L., Koonin, E.V., Brinton, M.A. Virology (1993)
- Noninvasive targeted imaging of matrix metalloproteinase activation in a murine model of postinfarction remodeling. Su, H., Spinale, F.G., Dobrucki, L.W., Song, J., Hua, J., Sweterlitsch, S., Dione, D.P., Cavaliere, P., Chow, C., Bourke, B.N., Hu, X.Y., Azure, M., Yalamanchili, P., Liu, R., Cheesman, E.H., Robinson, S., Edwards, D.S., Sinusas, A.J. Circulation (2005)
- Studies on the mechanism of NK cell lysis. Quan, P.C., Ishizaka, T., Bloom, B.R. J. Immunol. (1982)
- Studies on rLMP7, a beta-subunit of the multicatalytic proteinase. Ren, L., Clawson, G.A. Exp. Cell Res. (1997)
- Induction of proteasome expression in skeletal muscle is attenuated by inhibitors of NF-kappaB activation. Wyke, S.M., Russell, S.T., Tisdale, M.J. Br. J. Cancer (2004)
- Development of an in-vitro model system to investigate the mechanism of muscle protein catabolism induced by proteolysis-inducing factor. Gomes-Marcondes, M.C., Smith, H.J., Cooper, J.C., Tisdale, M.J. Br. J. Cancer (2002)
- Combination efficacy of doxorubicin and adenoviral methioninase gene therapy with prodrug selenomethionine. Gupta, A., Miki, K., Xu, M., Yamamoto, N., Moossa, A.R., Hoffman, R.M. Anticancer Res. (2003)
- Peroxynitrite alters the catalytic activity of rodent liver proteasome in vitro and in vivo. Osna, N.A., Haorah, J., Krutik, V.M., Donohue, T.M. Hepatology (2004)
- Serine proteases in rodent hippocampus. Davies, B.J., Pickard, B.S., Steel, M., Morris, R.G., Lathe, R. J. Biol. Chem. (1998)
- Cytoplasmic trafficking of minute virus of mice: low-pH requirement, routing to late endosomes, and proteasome interaction. Ros, C., Burckhardt, C.J., Kempf, C. J. Virol. (2002)
- Proteinases are involved in both DNA fragmentation and membrane damage during CTL-mediated target cell killing. Helgason, C.D., Atkinson, E.A., Pinkoski, M.J., Bleackley, R.C. Exp. Cell Res. (1995)
- A new structural class of proteasome inhibitors that prevent NF-kappa B activation. Lum, R.T., Kerwar, S.S., Meyer, S.M., Nelson, M.G., Schow, S.R., Shiffman, D., Wick, M.M., Joly, A. Biochem. Pharmacol. (1998)
- Cloning and characterization of mouse klk27, a novel tissue kallikrein expressed in testicular Leydig cells and exhibiting chymotrypsin-like specificity. Matsui, H., Moriyama, A., Takahashi, T. Eur. J. Biochem. (2000)
- The proteasome as a lipopolysaccharide-binding protein in macrophages: differential effects of proteasome inhibition on lipopolysaccharide-induced signaling events. Qureshi, N., Perera, P.Y., Shen, J., Zhang, G., Lenschat, A., Splitter, G., Morrison, D.C., Vogel, S.N. J. Immunol. (2003)
- Myonase is localized in skeletal muscle myofibrils. Hori, S., Yamada, M., Ohtani, S., Hori, C., Yokomizo, T., Webb, T., Shimokawa, T. J. Biochem. (2002)
- Increased expression of the ubiquitin-proteasome pathway in murine myotubes by proteolysis-inducing factor (PIF) is associated with activation of the transcription factor NF-kappaB. Whitehouse, A.S., Tisdale, M.J. Br. J. Cancer (2003)
- Expression and utilization of chymotrypsin-like but not trypsin-like serine protease enzymes by nonspecific T killer cells activated by anti-CD3 monoclonal antibody. Kaiser, M., Hoskin, D.W. Cell. Immunol. (1992)
- The tumor proteasome is a primary target for the natural anticancer compound Withaferin A isolated from "Indian winter cherry". Yang, H., Shi, G., Dou, Q.P. Mol. Pharmacol. (2007)
- Effect of a tumour-produced lipid-mobilizing factor on protein synthesis and degradation. Islam-Ali, B.S., Tisdale, M.J. Br. J. Cancer (2001)
- Basic isozymes of chymotrypsin-like esteroprotease from the mouse submandibular gland. Takuma, T., Ichida, T., Kumegawa, M. Biochim. Biophys. Acta (1983)