Gene Review:
MCAT - malonyl CoA:ACP acyltransferase...
Homo sapiens
Synonyms:
FASN2C, MCT, MT, Malonyl-CoA-acyl carrier protein transacylase, mitochondrial, Mitochondrial malonyl CoA:ACP acyltransferase, ...
- Metallothioneins and zinc dysregulation contribute to neurodevelopmental damage in a model of perinatal viral infection. Williams, B.L., Yaddanapudi, K., Kirk, C.M., Soman, A., Hornig, M., Lipkin, W.I. Brain Pathol. (2006)
- Activation of metallothionein gene expression by hypoxia involves metal response elements and metal transcription factor-1. Murphy, B.J., Andrews, G.K., Bittel, D., Discher, D.J., McCue, J., Green, C.J., Yanovsky, M., Giaccia, A., Sutherland, R.M., Laderoute, K.R., Webster, K.A. Cancer Res. (1999)
- Spontaneous vitiligo in an animal model for human melanoma: role of tumor-specific CD8+ T cells. Lengagne, R., Le Gal, F.A., Garcette, M., Fiette, L., Ave, P., Kato, M., Briand, J.P., Massot, C., Nakashima, I., Rénia, L., Guillet, J.G., Prévost-Blondel, A. Cancer Res. (2004)
- Catalytically inactive protein phosphatase 2A can bind to polyomavirus middle tumor antigen and support complex formation with pp60(c-src). Ogris, E., Mudrak, I., Mak, E., Gibson, D., Pallas, D.C. J. Virol. (1999)
- Metallothionein 2A expression is associated with cell proliferation in breast cancer. Jin, R., Chow, V.T., Tan, P.H., Dheen, S.T., Duan, W., Bay, B.H. Carcinogenesis (2002)
- Metallothioneins in brain--the role in physiology and pathology. Aschner, M., Cherian, M.G., Klaassen, C.D., Palmiter, R.D., Erickson, J.C., Bush, A.I. Toxicol. Appl. Pharmacol. (1997)
- Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements. Lee, W., Mitchell, P., Tjian, R. Cell (1987)
- Metallothionein gene cluster is split by chromosome 16 rearrangements in myelomonocytic leukaemia. Le Beau, M.M., Diaz, M.O., Karin, M., Rowley, J.D. Nature (1985)
- Metallothionein mRNA induction in HeLa cells in response to zinc or dexamethasone is a primary induction response. Karin, M., Andersen, R.D., Slater, E., Smith, K., Herschman, H.R. Nature (1980)
- Overexpression of metallothionein confers resistance to the cytotoxic effect of TNF with cadmium in MCF-7 breast carcinoma cells. Sciavolino, P.J., Lee, T.H., Vilcek, J. Lymphokine Cytokine Res. (1992)
- Prostaglandins E and F in endocrine diarrheagenic syndromes. Jaffe, B.M., Condon, S. Ann. Surg. (1976)
- Hypocaloric feeding in obese women: metabolic effects of medium-chain triglyceride substitution. Yost, T.J., Eckel, R.H. Am. J. Clin. Nutr. (1989)
- Pentavalent technetium-99m (V)-DMSA uptake in a pheochromocytoma in a patient with Sipple's syndrome. Adams, B.K., Fataar, A., Byrne, M.J., Levitt, N.S., Matley, P.J. J. Nucl. Med. (1990)
- Cytotoxicity of nitric oxide is alleviated by zinc-mediated expression of antioxidant genes. Chung, M.J., Hogstrand, C., Lee, S.J. Exp. Biol. Med. (Maywood) (2006)
- Cloned transcription factor MTF-1 activates the mouse metallothionein I promoter. Radtke, F., Heuchel, R., Georgiev, O., Hergersberg, M., Gariglio, M., Dembic, Z., Schaffner, W. EMBO J. (1993)
- Association of arsenic-induced malignant transformation with DNA hypomethylation and aberrant gene expression. Zhao, C.Q., Young, M.R., Diwan, B.A., Coogan, T.P., Waalkes, M.P. Proc. Natl. Acad. Sci. U.S.A. (1997)
- The Drosophila homolog of mammalian zinc finger factor MTF-1 activates transcription in response to heavy metals. Zhang, B., Egli, D., Georgiev, O., Schaffner, W. Mol. Cell. Biol. (2001)
- Coordinate induction of metallothioneins I and II in rodent cells by UV irradiation. Fornace, A.J., Schalch, H., Alamo, I. Mol. Cell. Biol. (1988)
- The functional significance of brain metallothioneins. Aschner, M. FASEB J. (1996)
- Cell-type specific and differential regulation of the human metallothionein genes. Correlation with DNA methylation and chromatin structure. Jahroudi, N., Foster, R., Price-Haughey, J., Beitel, G., Gedamu, L. J. Biol. Chem. (1990)
- Localization Effect on the Metal Biosorption Capability of Recombinant Mammalian and Fish Metallothioneins in Escherichia coli. Kao, W.C., Chiu, Y.P., Chang, C.C., Chang, J.S. Biotechnol. Prog. (2006)
- The Zn- and Cd-Clusters of Recombinant Mammalian MT1 and MT4 Metallothionein Domains Include Sulfide Ligands. T??o, L., Villarreal, L., Atrian, S., Capdevila, M. Exp. Biol. Med. (Maywood) (2006)
- Interleukin-1 beta-mediated metallothionein induction and cytoprotection against cadmium and cis-diamminedichloroplatinum. Kondo, Y., Kuo, S.M., Lazo, J.S. J. Pharmacol. Exp. Ther. (1994)
- The DNA binding activity of metal response element-binding transcription factor-1 is activated in vivo and in vitro by zinc, but not by other transition metals. Bittel, D., Dalton, T., Samson, S.L., Gedamu, L., Andrews, G.K. J. Biol. Chem. (1998)
- Epigenetic regulation of metallothionein-i gene expression: differential regulation of methylated and unmethylated promoters by DNA methyltransferases and methyl CpG binding proteins. Majumder, S., Kutay, H., Datta, J., Summers, D., Jacob, S.T., Ghoshal, K. J. Cell. Biochem. (2006)
- Chromium(VI) down-regulates heavy metal-induced metallothionein gene transcription by modifying transactivation potential of the key transcription factor, metal-responsive transcription factor 1. Majumder, S., Ghoshal, K., Summers, D., Bai, S., Datta, J., Jacob, S.T. J. Biol. Chem. (2003)
- Human metallothionein gene MT1L mRNA is present in several human tissues but is unlikely to produce a metallothionein protein. Holloway, A.F., Stennard, F.A., West, A.K. FEBS Lett. (1997)
- Expression of different metallothionein messenger ribonucleic acids in motor cortex, spinal cord and liver from patients with amyotrophic lateral sclerosis. Blaauwgeers, H.G., Anwar Chand, M., van den Berg, F.M., Vianney de Jong, J.M., Troost, D. J. Neurol. Sci. (1996)
- Metallothionein IIA is up-regulated by hypoxia in human A431 squamous carcinoma cells. Murphy, B.J., Laderoute, K.R., Chin, R.J., Sutherland, R.M. Cancer Res. (1994)
- Characteristics of microtubules at the different stages of neuronal differentiation and maturation. Meininger, V., Binet, S. Int. Rev. Cytol. (1989)
- The cellular proteins which can associate specifically with polyomavirus middle T antigen in human 293 cells include the major human 70-kilodalton heat shock proteins. Pallas, D.C., Morgan, W., Roberts, T.M. J. Virol. (1989)
- Identification and spatial analysis of metallothioneins expressed by the adult human lens. Oppermann, B., Zhang, W., Magabo, K., Kantorow, M. Invest. Ophthalmol. Vis. Sci. (2001)