Gene Review:
hly - listeriolysin O
Listeria monocytogenes serotype 4b str. F2365
- ActA is required for crossing of the fetoplacental barrier by Listeria monocytogenes. Le Monnier, A., Autret, N., Join-Lambert, O.F., Jaubert, F., Charbit, A., Berche, P., Kayal, S. Infect. Immun. (2007)
- Identification and characterization of nucleotide sequence differences in three virulence-associated genes of listeria monocytogenes strains representing clinically important serotypes. Vines, A., Swaminathan, B. Curr. Microbiol. (1998)
- Construction, characterization, and use of two Listeria monocytogenes site-specific phage integration vectors. Lauer, P., Chow, M.Y., Loessner, M.J., Portnoy, D.A., Calendar, R. J. Bacteriol. (2002)
- Listeria monocytogenes protein p60 affects hemolytic activity and uptake of bacteria by macrophages. Krawczyk-Balska, A., Markiewicz, Z., Bielecki, J. Folia Microbiol. (Praha) (2005)
- Expression of listeriolysin O and ActA by intracellular and extracellular Listeria monocytogenes. Moors, M.A., Levitt, B., Youngman, P., Portnoy, D.A. Infect. Immun. (1999)
- A PEST-like sequence in listeriolysin O essential for Listeria monocytogenes pathogenicity. Decatur, A.L., Portnoy, D.A. Science (2000)
- Intracellular antibody neutralizes Listeria growth. Edelson, B.T., Unanue, E.R. Immunity (2001)
- Type I interferon sensitizes lymphocytes to apoptosis and reduces resistance to Listeria infection. Carrero, J.A., Calderon, B., Unanue, E.R. J. Exp. Med. (2004)
- The bvr locus of Listeria monocytogenes mediates virulence gene repression by beta-glucosides. Brehm, K., Ripio, M.T., Kreft, J., Vázquez-Boland, J.A. J. Bacteriol. (1999)
- The Listeria monocytogenes hemolysin has an acidic pH optimum to compartmentalize activity and prevent damage to infected host cells. Glomski, I.J., Gedde, M.M., Tsang, A.W., Swanson, J.A., Portnoy, D.A. J. Cell Biol. (2002)
- Molecular basis of listeriolysin O pH dependence. Schuerch, D.W., Wilson-Kubalek, E.M., Tweten, R.K. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Mechanisms of T cell epitope immunodominance analyzed in murine listeriosis. Safley, S.A., Jensen, P.E., Reay, P.A., Ziegler, H.K. J. Immunol. (1995)
- Attenuated mutants of the intracellular bacterium Listeria monocytogenes obtained by single amino acid substitutions in listeriolysin O. Michel, E., Reich, K.A., Favier, R., Berche, P., Cossart, P. Mol. Microbiol. (1990)
- Differential interaction of the transcription factor PrfA and the PrfA-activating factor (Paf) of Listeria monocytogenes with target sequences. Dickneite, C., Böckmann, R., Spory, A., Goebel, W., Sokolovic, Z. Mol. Microbiol. (1998)
- Ribotypes and virulence gene polymorphisms suggest three distinct Listeria monocytogenes lineages with differences in pathogenic potential. Wiedmann, M., Bruce, J.L., Keating, C., Johnson, A.E., McDonough, P.L., Batt, C.A. Infect. Immun. (1997)
- Mycobacterium bovis Bacille Calmette-Guérin strains secreting listeriolysin of Listeria monocytogenes. Hess, J., Miko, D., Catic, A., Lehmensiek, V., Russell, D.G., Kaufmann, S.H. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Interactions of Listeria monocytogenes with mammalian cells during entry and actin-based movement: bacterial factors, cellular ligands and signaling. Cossart, P., Lecuit, M. EMBO J. (1998)
- Engineered E. coli delivers therapeutic genes to the colonic mucosa. Castagliuolo, I., Beggiao, E., Brun, P., Barzon, L., Goussard, S., Manganelli, R., Grillot-Courvalin, C., Palù, G. Gene Ther. (2005)
- Mammalian cells transfected with the listeriolysin gene exhibit enhanced proliferation and focus formation. Demuth, A., Chakraborty, T., Krohne, G., Goebel, W. Infect. Immun. (1994)
- Carbon-source regulation of virulence gene expression in Listeria monocytogenes. Milenbachs, A.A., Brown, D.P., Moors, M., Youngman, P. Mol. Microbiol. (1997)
- Listeriolysin O as a reporter to identify constitutive and in vivo-inducible promoters in the pathogen Listeria monocytogenes. Dubail, I., Berche, P., Charbit, A. Infect. Immun. (2000)
- Identification of a new locus in Listeria monocytogenes involved in cellobiose-dependent repression of hly expression. Huillet, E., Larpin, S., Pardon, P., Berche, P. FEMS Microbiol. Lett. (1999)
- Induction of murine peritoneal gamma/delta T cells and their role in resistance to bacterial infection. Skeen, M.J., Ziegler, H.K. J. Exp. Med. (1993)
- pH-dependent perforation of macrophage phagosomes by listeriolysin O from Listeria monocytogenes. Beauregard, K.E., Lee, K.D., Collier, R.J., Swanson, J.A. J. Exp. Med. (1997)
- How seryl-phosphorylated HPr inhibits PrfA, a transcription activator of Listeria monocytogenes virulence genes. Herro, R., Poncet, S., Cossart, P., Buchrieser, C., Gouin, E., Glaser, P., Deutscher, J. J. Mol. Microbiol. Biotechnol. (2005)
- Positive selection of mutations leading to loss or reduction of transcriptional activity of PrfA, the central regulator of Listeria monocytogenes virulence. Herler, M., Bubert, A., Goetz, M., Vega, Y., Vazquez-Boland, J.A., Goebel, W. J. Bacteriol. (2001)
- IFN-beta increases listeriolysin O-induced membrane permeabilization and death of macrophages. Zwaferink, H., Stockinger, S., Hazemi, P., Lemmens-Gruber, R., Decker, T. J. Immunol. (2008)
- Specific binding of the Listeria monocytogenes transcriptional regulator PrfA to target sequences requires additional factor(s) and is influenced by iron. Böckmann, R., Dickneite, C., Middendorf, B., Goebel, W., Sokolovic, Z. Mol. Microbiol. (1996)
- Rational design of DNA sequence-based strategies for subtyping Listeria monocytogenes. Cai, S., Kabuki, D.Y., Kuaye, A.Y., Cargioli, T.G., Chung, M.S., Nielsen, R., Wiedmann, M. J. Clin. Microbiol. (2002)
- Apoptosis of mouse dendritic cells is triggered by listeriolysin, the major virulence determinant of Listeria monocytogenes. Guzmán, C.A., Domann, E., Rohde, M., Bruder, D., Darji, A., Weiss, S., Wehland, J., Chakraborty, T., Timmis, K.N. Mol. Microbiol. (1996)
- Virulence phenotyping and molecular characterization of a low-pathogenicity isolate of Listeria monocytogenes from cow's milk. Jiang, L.L., Xu, J.J., Chen, N., Shuai, J.B., Fang, W.H. Acta Biochim. Biophys. Sin. (Shanghai) (2006)
- Use of listeriolysin O and internalin A in a seroepidemiological study of listeriosis in Swiss dairy cows. Boerlin, P., Boerlin-Petzold, F., Jemmi, T. J. Clin. Microbiol. (2003)
- PrfA mediates specific binding of RNA polymerase of Listeria monocytogenes to PrfA-dependent virulence gene promoters resulting in a transcriptionally active complex. Böckmann, R., Dickneite, C., Goebel, W., Bohne, J. Mol. Microbiol. (2000)
- Presentation of Listeria monocytogenes antigens by major histocompatibility complex class I molecules to CD8 cytotoxic T lymphocytes independent of listeriolysin secretion and virulence. Szalay, G., Hess, J., Kaufmann, S.H. Eur. J. Immunol. (1994)
- Detection of Listeria monocytogenes from a model food by fluorescence resonance energy transfer-based PCR with an asymmetric fluorogenic probe set. Koo, K., Jaykus, L.A. Appl. Environ. Microbiol. (2003)