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Gene Review

GOT2  -  glutamic-oxaloacetic transaminase 2,...

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Disease relevance of GOT2


High impact information on GOT2


Chemical compound and disease context of GOT2


Biological context of GOT2


Anatomical context of GOT2


Associations of GOT2 with chemical compounds


Regulatory relationships of GOT2


Other interactions of GOT2


Analytical, diagnostic and therapeutic context of GOT2


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  13. Complete amino acid sequence of mitochondrial aspartate aminotransferase from pig heart muscle. Cyanogen bromide peptides. Sakakibara, R., Kagamiyama, H., Tanase, S., Morino, Y., Wada, H. J. Biol. Chem. (1980) [Pubmed]
  14. Site-specific methylation of a strategic lysyl residue in aspartate aminotransferase. Roberts, W.J., Hubert, E., Iriarte, A., Martinez-Carrion, M. J. Biol. Chem. (1988) [Pubmed]
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  18. Resonance Raman spectra of the pyridoxal coenzyme in aspartate aminotransferase. Evidence for pyridine protonation and a novel photochemical H/D exchange at the imine carbon atom. Benecky, M.J., Copeland, R.A., Rava, R.P., Feldhaus, R., Scott, R.D., Metzler, C.M., Metzler, D.E., Spiro, T.G. J. Biol. Chem. (1985) [Pubmed]
  19. The covalent structure of mitochondrial aspartate aminotransferase from chicken. Identification of segments of the polypeptide chain invariant specifically in the mitochondrial isoenzyme. Graf-Hausner, U., Wilson, K.J., Christen, P. J. Biol. Chem. (1983) [Pubmed]
  20. Presequence binding factor-dependent and -independent import of proteins into mitochondria. Murakami, K., Tanase, S., Morino, Y., Mori, M. J. Biol. Chem. (1992) [Pubmed]
  21. Mechanism of the irreversible inhibition of aspartate aminotransferase by the bacterial toxin L-2-amino-4-methoxy-trans-3-butenoic acid. Rando, R.R., Relyea, N., Cheng, L. J. Biol. Chem. (1976) [Pubmed]
  22. Kinetic advantages of hetero-enzyme complexes with glutamate dehydrogenase and the alpha-ketoglutarate dehydrogenase complex. Fahien, L.A., MacDonald, M.J., Teller, J.K., Fibich, B., Fahien, C.M. J. Biol. Chem. (1989) [Pubmed]
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  25. A spin label substrate analogue as active site-directed modifying agent. Tryptophan 140 of aspartate aminotransferase. Iriarte, A., Martinez-Carrion, M. J. Biol. Chem. (1983) [Pubmed]
  26. Prolactin stimulates transcription of aspartate aminotransferase in prostate cells. Franklin, R.B., Ekiko, D.B., Costello, L.C. Mol. Cell. Endocrinol. (1992) [Pubmed]
  27. Large-scale purification and some properties of the mitochondrial aspartate aminotransferase from pig heart. Barra, D., Bossa, F., Doonan, S., Fahmy, H.M., Martini, F., Hughes, G.J. Eur. J. Biochem. (1976) [Pubmed]
  28. Concomitant purification of three porcine heart mitochondrial enzymes: citrate synthase, aspartate aminotransferase, and malate dehydrogenase. McEvily, A.J., Flint, A.J., Harrison, J.H. Anal. Biochem. (1985) [Pubmed]
  29. Limited proteolysis as a probe of conformational changes in aspartate aminotransferase from Sulfolobus solfataricus. Arnone, M.I., Birolo, L., Giamberini, M., Cubellis, M.V., Nitti, G., Sannia, G., Marino, G. Eur. J. Biochem. (1992) [Pubmed]
  30. The ionization states of the 5'-phosphate group in the various coenzyme forms bound to mitochondrial aspartate aminotransferase. Sanchez-Ruiz, J.M., Iriarte, A., Martinez-Carrion, M. Arch. Biochem. Biophys. (1991) [Pubmed]
  31. Slow-cooling protocols for crystallographic refinement by simulated annealing. Brünger, A.T., Krukowski, A., Erickson, J.W. Acta Crystallogr., A, Found. Crystallogr. (1990) [Pubmed]
  32. Cloning and sequence analysis of a cDNA encoding porcine mitochondrial aspartate aminotransferase precursor. Joh, T., Nomiyama, H., Maeda, S., Shimada, K., Morino, Y. Proc. Natl. Acad. Sci. U.S.A. (1985) [Pubmed]
  33. Coenzyme active site occupancy as an indicator of independence of the subunits of mitochondrial aspartate aminotransferase. Iriarte, A., Farach, H.A., Martinez-Carrion, M. J. Biol. Chem. (1984) [Pubmed]
  34. Differential scanning calorimetry of cytoplasmic aspartate transaminase. Relimpio, A., Iriarte, A., Chlebowski, J.F., Martinez-Carrion, M. J. Biol. Chem. (1981) [Pubmed]
  35. Partial purification and characterization of aspartate aminotransferases from seedling oat leaves. Reed, R.E., Hess, J.L. J. Biol. Chem. (1975) [Pubmed]
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