Disease relevance of PALM

• We interviewed and tested 1082 (99.8 percent) of 1084 consecutive pregnant women who registered for prenatal care at a public health clinic in western Palm Beach County, Florida. This rural agricultural area of about 36,000 people is known to have a high prevalence of HIV infection [1].
• First case of bioterrorism-related inhalational anthrax in the United States, Palm Beach County, Florida, 2001 [2].
• Update on surgical treatment of the epilepsies. Summary of the Second International Palm Desert Conference on the Surgical Treatment of the Epilepsies (1992) [3].
• Prevalence of hepatitis B surface antigen among women receiving prenatal care at the Palm Beach County Health Department [4].
• In support of this hypothesis, we found that the Dade county patients showed significant increases in physician-rated clinical relapses and exacerbations in frequency of several categories of self-reported CFS physical symptoms as compared to the Broward/Palm Beach county patients [5].

Psychiatry related information on PALM

• A total of 420 adults between 18 and 91 years of age carried palm pilot (Palm M100; PalmOne, Milpitas, CA) devices and performed several reaction time trials when prompted at random times during the day [6].
• Each day, participants were signaled six times by the Palm top and answered questions about mood, behavior, stressful events, and self-appraisal [7].
• Detoxification in the Palm Beach Community Mental Health Center is fully described [8].
• We developed and used a computerized observational software Behavior and Social Interaction Software (BASIS) with a preloaded coding scheme installed on a handheld Palm device to record complex observations of interactions between children and socializing agents [9].

High impact information on PALM

• The leaving ubiquitin moiety is specifically coordinated by the Fingers, with its C terminus placed in the active site between the Palm and the Thumb [10].
• Conversely, HIP14 is catalytically invariant toward paralemmin and synaptotagmin VII [11].
• Contrasting the task with the highest semantic component, a variation on the Pyramids and Palm Trees paradigm, with a size discrimination task resulted in focal activation in the anterior inferior temporal lobe, focused in the parahippocampal gyrus [12].
• [J.A. Hammarback, S.L. Palm, L.T. Furcht, and P.C. Letourneau (1985). J. Neurosci. Res. 13, 213-220] guided peripheral nervous system neurites (dissociated dorsal root ganglia and sympathetic ganglia) and central nervous system neurites (dissociated spinal cord and brain) [13].
• The peptide T345-359 representing the fourth intracellular loop of the avian beta-adrenoceptor has been shown to strongly inhibit receptor-mediated adenylate cyclase activity [Münch, G., Dees, C., Hekman, M., & Palm, D. (1991) Eur. J. Biochem. 198, 357-364] [14].

Chemical compound and disease context of PALM

• In the present trial, we investigated the antioxidant properties of Palm Vitee, a gamma-tocotrienol-, and alpha-tocopherol enriched fraction of palm oil, in patients with carotid atherosclerosis [15].

Biological context of PALM

• Moreover, we have performed chromosomal assignments of the human and mouse paralemmin genes, localizing them to regions of homology at human 19p13.3 and the central mouse chromosome 10 [16].
• As it is a candidate for genetic disorders that affect membrane functions, we have determined the structure of the human paralemmin gene, PALM, showing that it is organized into nine exons [16].
• Structure of the human paralemmin gene (PALM), mapping to human chromosome 19p13.3 and mouse chromosome 10, and exclusion of coding mutations in grizzled, mocha, jittery, and hesitant mice [16].
• The unrefined molecular structure of the VREI dimer has been published (Epp, O., Colman, P., Fehlhammer, H., Bode, W., Schiffer, M., Huber, R., and Palm, W. (1974), Eur. J. Biochem. 45, 513) [17].
• Report on apoptosis and immunity, 31 May-3 June 2005, Palm Cove, Queensland, Australia [18].

Anatomical context of PALM

• Paralemmin is a newly identified protein that is associated with the plasma membrane and with intracellular membranes through a lipid anchor [16].
• Paralemmin is a novel lipid-anchored protein, which is highly expressed in neuronal plasma membranes [19].
• The postoperative results of the Cartagena program were compared with those reported at the Second International Palm Desert Conference 1992, which revealed a similar rate of postoperative seizure control in temporal lobe epilepsy, slightly inferior results with hemispherectomy, and slightly better results with anterior callosotomy [20].
• Mosaics of paralemmin-positive and paralemmin-negative cells are observed in proximal tubules, the parietal epithelium of Bowman's capsule and the endothelium of many blood vessels [21].
• It may be concluded that specific phase relation (12-hr) between circadian serotonergic and dopaminergic oscillations may induce breeding condition in regressing gonad of Indian Palm Squirrel during post-reproductive phase of annual gonadal cycle [22].

Associations of PALM with chemical compounds

• Paralemmin interacts with D3 dopamine receptors: implications for membrane localization and cAMP signaling [19].
• Consistent with this observation, paralemmin expression decreased dopamine-stimulated adenylate cyclase activity [19].
• However, paralemmin also decreased basal, isoproterenol and forskolin-stimulated adenylate cyclase activity, suggesting a more general cellular function for paralemmin [19].
• The use of global risk scoring aids, including the Palm Pilot cholesterol risk calculators, can improve guideline adherence and provide education and motivation to patients to maintain compliance [23].
• To validate this approach, we compared taste intensity judgments of six sucrose solutions (0.03, 0.06, 0.12, 0.24, 0.48, and 0.96 M), using a labeled magnitude scale either presented in expandable form on a palmtop computer (Palm scale) or in conventional (nonexpandable) form on a standard 17'' PC monitor (PC scale) [24].

Analytical, diagnostic and therapeutic context of PALM

• Utilizing co-immunoprecipitation and glutathione-S-transferase (GST) pulldown strategies, we demonstrate that paralemmin interacts exclusively with D3, but not D2 or D4 dopamine receptors or beta-adrenergic receptors [19].
• Random urine samples from hospitalized patients (n = 550) and seeded sterile filtered urine samples (n = 730) were used to test a membrane filtration technique, Qualture (Future Medical Technologies International, Inc., West Palm Beach, Fla.), for the detection and identification of uropathogens [25].
• To identify risk factors for infection, the authors performed a 1998-2000 cross-sectional study in western Palm Beach County, Florida, using a population-based random household survey [26].
• This organism is notorious for its association with a significant human poisoning incident on Palm Island, Australia, which resulted in the hospitalization of 148 people [27].
• Adults with overweight and obesity (n=61, 92% women, mean age 48.2 years, mean body mass index 32.3) were provided with a PalmZire 21 (Palm, Inc, Sunnyvale, CA) loaded with Calorie King's Diet Diary software (version 3.2.2, 2002, Family Health Network, Costa Mesa, CA) [28].

References