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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Antibody Affinity

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Disease relevance of Antibody Affinity


High impact information on Antibody Affinity


Chemical compound and disease context of Antibody Affinity


Biological context of Antibody Affinity


Anatomical context of Antibody Affinity


Associations of Antibody Affinity with chemical compounds


Gene context of Antibody Affinity

  • Proteins that co-purified with ABCA1 on an antibody affinity column were identified by liquid chromatographymass spectrometric analysis [30].
  • Measurements of individual antibody affinities coupled with kinetic analysis of equilibrium binding states also suggested that there are multiple conformational states of CCR5 [31].
  • We purified DMP1-PG with a monoclonal anti-DMP1 antibody affinity column [32].
  • The aim of the present study was to clarify the role of H-2 and Igh-1 genes in the regulation of antibody affinity and isotype composition of oxazolone-specific antibodies [33].
  • Soluble CR2 was prepared from tonsillar mononuclear cells and purified by antibody affinity chromatography [34].

Analytical, diagnostic and therapeutic context of Antibody Affinity


  1. Immunoreactivity of a 70 kD protein purified from Mycobacterium bovis Bacillus Calmette-Guerin by monoclonal antibody affinity chromatography. Britton, W.J., Hellqvist, L., Basten, A., Inglis, A.S. J. Exp. Med. (1986) [Pubmed]
  2. Characteristics of high-titer IgG antiphospholipid antibody in systemic lupus erythematosus patients with and without fetal death. Qamar, T., Levy, R.A., Sammaritano, L., Gharavi, A.E., Lockshin, M.D. Arthritis Rheum. (1990) [Pubmed]
  3. Purification and characterization of natural human interferon omega 1. Two alternative cleavage sites for the signal peptidase. Adolf, G.R., Maurer-Fogy, I., Kalsner, I., Cantell, K. J. Biol. Chem. (1990) [Pubmed]
  4. Cloning and expression of two novel hemin binding protein genes from Treponema denticola. Xu, X., Holt, S.C., Kolodrubetz, D. Infect. Immun. (2001) [Pubmed]
  5. Cloning and sequence analysis of cytadhesin P1 gene from Mycoplasma pneumoniae. Su, C.J., Tryon, V.V., Baseman, J.B. Infect. Immun. (1987) [Pubmed]
  6. TRF2 associates with DREF and directs promoter-selective gene expression in Drosophila. Hochheimer, A., Zhou, S., Zheng, S., Holmes, M.C., Tjian, R. Nature (2002) [Pubmed]
  7. The lymphotoxin beta receptor controls organogenesis and affinity maturation in peripheral lymphoid tissues. Fütterer, A., Mink, K., Luz, A., Kosco-Vilbois, M.H., Pfeffer, K. Immunity (1998) [Pubmed]
  8. Calretinin modifies presynaptic calcium signaling in frog saccular hair cells. Edmonds, B., Reyes, R., Schwaller, B., Roberts, W.M. Nat. Neurosci. (2000) [Pubmed]
  9. Tracing the development of single memory-lineage B cells in a highly defined immune response. Liu, A.H., Jena, P.K., Wysocki, L.J. J. Exp. Med. (1996) [Pubmed]
  10. Isolation and characterization of the nephritogenic antigen producing anti-tubular basement membrane disease. Clayman, M.D., Martinez-Hernandez, A., Michaud, L., Alper, R., Mann, R., Kefalides, N.A., Neilson, E.G. J. Exp. Med. (1985) [Pubmed]
  11. Antibody neutralization of HIV-1 and the potential for vaccine design. Sattentau, Q.J., Moulard, M., Brivet, B., Botto, F., Guillemot, J.C., Mondor, I., Poignard, P., Ugolini, S. Immunol. Lett. (1999) [Pubmed]
  12. Serum antibody levels and avidities to Escherichia coli O antigens and poliovirus type 1 antigen are increased in children treated for malignant disease. Abrahamsson, J., Carlsson, B., Mellander, L. Med. Pediatr. Oncol. (1999) [Pubmed]
  13. In vitro selection of a high affinity antibody to oestradiol using a phage display human antibody library. Pope, A., Pritchard, K., Williams, A., Roberts, A., Hackett, J.R., Mandecki, W., Johnson, K.S. Immunotechnology (1996) [Pubmed]
  14. Higher activity of recombinant bovine deoxyhypusine synthase vs. human deoxyhypusine synthase. Huang, J.K., Tsai, S., Huang, G.H., Gowda, P.G., Walzer, A.M., Wen, L. Protein Expr. Purif. (2004) [Pubmed]
  15. Stable oligosaccharide microheterogeneity at individual glycosylation sites of a murine major histocompatibility antigen derived from a B-cell lymphoma. Swiedler, S.J., Hart, G.W., Tarentino, A.L., Plummer, T.H., Freed, J.H. J. Biol. Chem. (1983) [Pubmed]
  16. The generation of a humanized, non-mitogenic CD3 monoclonal antibody which retains in vitro immunosuppressive properties. Bolt, S., Routledge, E., Lloyd, I., Chatenoud, L., Pope, H., Gorman, S.D., Clark, M., Waldmann, H. Eur. J. Immunol. (1993) [Pubmed]
  17. The J558 VH CDR3 region contributes little to antibody avidity; however, it is the recognition element for cognate T cell control of the alpha(1-->3) dextran-specific antibody response. Clemens, A., Rademaekers, A., Specht, C., Kölsch, E. Int. Immunol. (1998) [Pubmed]
  18. Correlation between the avidity of mouse-human chimeric IgG subclass monoclonal antibodies measured by solid-phase elution ELISA and biospecific interaction analysis (BIA). McCloskey, N., Turner, M.W., Goldblatt, T.D. J. Immunol. Methods (1997) [Pubmed]
  19. Purification of human alpha 2-plasmin inhibitor using monoclonal antibody column chromatography. Sumi, Y., Koike, Y., Ichikawa, Y., Aoki, N. J. Biochem. (1989) [Pubmed]
  20. Unique TATA-binding protein-containing complexes and cofactors involved in transcription by RNA polymerases II and III. Chiang, C.M., Ge, H., Wang, Z., Hoffmann, A., Roeder, R.G. EMBO J. (1993) [Pubmed]
  21. Subpopulations of common acute lymphoblastic leukemia antigen-positive lymphoid cells in normal bone marrow identified by hematopoietic differentiation antigens. Ryan, D., Kossover, S., Mitchell, S., Frantz, C., Hennessy, L., Cohen, H. Blood (1986) [Pubmed]
  22. Feedback regulation of granulopoiesis: polymerization of lactoferrin abrogates its ability to inhibit CSA production. Bagby, G.C., Bennett, R.M. Blood (1982) [Pubmed]
  23. Interaction of terminal transferase with single-stranded DNA. Robbins, D.J., Barkley, M.D., Coleman, M.S. J. Biol. Chem. (1987) [Pubmed]
  24. Assembly of progesterone receptor with heat shock proteins and receptor activation are ATP mediated events. Smith, D.F., Stensgard, B.A., Welch, W.J., Toft, D.O. J. Biol. Chem. (1992) [Pubmed]
  25. Purification and characterization of a human lung tumor-associated antigen. Braatz, J.A., McIntire, K.R., Princler, G.L., Kortright, K.H., Herberman, R.B. J. Natl. Cancer Inst. (1978) [Pubmed]
  26. Integrin (the CSAT antigen): functionality requires oligomeric integrity. Buck, C.A., Shea, E., Duggan, K., Horwitz, A.F. J. Cell Biol. (1986) [Pubmed]
  27. A prostate antigen in sera of prostatic cancer patients. Papsidero, L.D., Wang, M.C., Valenzuela, L.A., Murphy, G.P., Chu, T.M. Cancer Res. (1980) [Pubmed]
  28. Monoclonal, but not polyclonal, antibodies protect against Plasmodium yoelii sporozoites. Charoenvit, Y., Mellouk, S., Cole, C., Bechara, R., Leef, M.F., Sedegah, M., Yuan, L.F., Robey, F.A., Beaudoin, R.L., Hoffman, S.L. J. Immunol. (1991) [Pubmed]
  29. Reevaluation of the ammonium sulfate assay for DNA antibody. Rubin, R.L., Lafferty, J., Carr, R.I. Arthritis Rheum. (1978) [Pubmed]
  30. Purification of ATP-binding cassette transporter A1 and associated binding proteins reveals the importance of beta1-syntrophin in cholesterol efflux. Okuhira, K., Fitzgerald, M.L., Sarracino, D.A., Manning, J.J., Bell, S.A., Goss, J.L., Freeman, M.W. J. Biol. Chem. (2005) [Pubmed]
  31. Epitope mapping of CCR5 reveals multiple conformational states and distinct but overlapping structures involved in chemokine and coreceptor function. Lee, B., Sharron, M., Blanpain, C., Doranz, B.J., Vakili, J., Setoh, P., Berg, E., Liu, G., Guy, H.R., Durell, S.R., Parmentier, M., Chang, C.N., Price, K., Tsang, M., Doms, R.W. J. Biol. Chem. (1999) [Pubmed]
  32. A chondroitin sulfate chain attached to the bone dentin matrix protein 1 NH2-terminal fragment. Qin, C., Huang, B., Wygant, J.N., McIntyre, B.W., McDonald, C.H., Cook, R.G., Butler, W.T. J. Biol. Chem. (2006) [Pubmed]
  33. The influence of Igh-1 genes on the class and subclass distribution of oxazolone-specific antibodies. László, G., Rajnavölgyi, E., Andó, I., Gergely, J. Immunogenetics (1985) [Pubmed]
  34. Enhanced binding of immune complexes processed by erythrocyte CR1 (CD 35) receptors to purified CR2 (CD 21) receptors from tonsillar mononuclear cells. Rask, R., Rasmussen, J.M., Jepsen, H.H., Svehag, S.E. APMIS (1989) [Pubmed]
  35. A collaborative study for the evaluation of lectin-reactive alpha-fetoproteins in early detection of hepatocellular carcinoma. Taketa, K., Endo, Y., Sekiya, C., Tanikawa, K., Koji, T., Taga, H., Satomura, S., Matsuura, S., Kawai, T., Hirai, H. Cancer Res. (1993) [Pubmed]
  36. Characterization of a monoclonal antibody against latex protein associated with latex allergy. Kurup, V.P., Kumar, A., Kelly, K.J., Fink, J.N. J. Allergy Clin. Immunol. (1993) [Pubmed]
  37. Functional assessment of pathogenic IgG subclasses in chronic autoimmune urticaria. Soundararajan, S., Kikuchi, Y., Joseph, K., Kaplan, A.P. J. Allergy Clin. Immunol. (2005) [Pubmed]
  38. IgA antibodies to Toxoplasma gondii in human tears. Meek, B., Klaren, V.N., van Haeringen, N.J., Kijlstra, A., Peek, R. Invest. Ophthalmol. Vis. Sci. (2000) [Pubmed]
  39. Bulk purification of a naturally occurring soluble form of RT1-A class I major histocompatibility complex antigens from DA rat liver, and studies of specific immunosuppression. Spencer, S.C., Fabre, J.W. Transplantation (1987) [Pubmed]
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