The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Rete Testis

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Rete Testis


High impact information on Rete Testis


Biological context of Rete Testis


Anatomical context of Rete Testis

  • Combined administration of DES (0.1 micro g) plus GnRHa or flutamide induced significantly greater distension/overgrowth of the rete testis and efferent ducts (ED) and a reduction in epithelial cell height of the ED than did DES (0.1 micro g) administered alone [14].
  • This hypothesis is contrary to the long standing 'Tuck' hypothesis which suggested that the source of luminal fluid in the seminiferous tubule originated from secretions of Sertoli cells as well as from distal testicular structures, e.g. the rete testis [15].
  • In the marmoset, but not the rat, AQP-1 was also expressed in the epithelium of the rete testis [16].
  • Since rete testis fluid entering and cauda epididymal fluid leaving the epididymis contained at least fourfold more oxytocin than testicular venous plasma, it was concluded that regional differences in epithelial concentration of oxytocin may have been masked by oxytocin contained in the luminal fluid [17].
  • In control testes, the expression of alpha-inhibin and cytokeratin was limited to a Sertoli cell component and rete testis, respectively [18].

Associations of Rete Testis with chemical compounds


Gene context of Rete Testis


Analytical, diagnostic and therapeutic context of Rete Testis


  1. Risk-adapted management for patients with clinical stage I seminoma: the Second Spanish Germ Cell Cancer Cooperative Group study. Aparicio, J., Germà, J.R., García del Muro, X., Maroto, P., Arranz, J.A., Sáenz, A., Barnadas, A., Dorca, J., Gumà, J., Olmos, D., Bastús, R., Carles, J., Almenar, D., Sánchez, M., Paz-Ares, L., Satrústegui, J.J., Mellado, B., Balil, A., López-Brea, M., Sánchez, A. J. Clin. Oncol. (2005) [Pubmed]
  2. Adenocarcinoma of the rete testis. Diethylstilbestrol-induced lesions of the mouse rete testis. Newbold, R.R., Bullock, B.C., McLachlan, J.A. Am. J. Pathol. (1986) [Pubmed]
  3. Evidence of interepithelial seminoma spread into the rete testis by immunostaining of paraffin sections with antibodies against cytokeratin and vimentin. Düe, W., Loy, V. Urol. Res. (1988) [Pubmed]
  4. The absence of specific interactions of Sertoli-cell-secreted proteins with antibodies directed against H-Y antigen. Gore-Langton, R.E., Tung, P.S., Fritz, I.B. Cell (1983) [Pubmed]
  5. A role for oestrogens in the male reproductive system. Hess, R.A., Bunick, D., Lee, K.H., Bahr, J., Taylor, J.A., Korach, K.S., Lubahn, D.B. Nature (1997) [Pubmed]
  6. Androgen binding proteins of testis, epididymis, and plasma in man and monkey. Vigersky, R.A., Loriaux, D.L., Howards, S.S., Hodgen, G.B., Lipsett, M.B., Chrambach, A. J. Clin. Invest. (1976) [Pubmed]
  7. Lesions of the rete testis in mice exposed prenatally to diethylstilbestrol. Newbold, R.R., Bullock, B.C., McLachlan, J.A. Cancer Res. (1985) [Pubmed]
  8. Purification and characterization of a cell-aggregating factor (clusterin), the major glycoprotein in ram rete testis fluid. Blaschuk, O., Burdzy, K., Fritz, I.B. J. Biol. Chem. (1983) [Pubmed]
  9. Production of the cysteine proteinase inhibitor cystatin C by rat Sertoli cells. Esnard, A., Esnard, F., Guillou, F., Gauthier, F. FEBS Lett. (1992) [Pubmed]
  10. Expression of the clusterin gene in the tissues of Booroola sheep which were homozygotes or non-carriers of the fecundity gene FecB. Fleming, J.S., Greenwood, P.J., Chen, C.L. J. Mol. Endocrinol. (1992) [Pubmed]
  11. Immunolocalization of clusterin in the ram testis, rete testis, and excurrent ducts. Tung, P.S., Fritz, I.B. Biol. Reprod. (1985) [Pubmed]
  12. Studies of the androgen binding protein in the rete testis fluid of the ram and its relation to sexual season. Jegou, B., Dacheux, J.L., Terqui, M., Garnier, D.H., Courot, M. Mol. Cell. Endocrinol. (1978) [Pubmed]
  13. Rat clusterin isolated from primary Sertoli cell-enriched culture medium is sulfated glycoprotein-2 (SGP-2). Cheng, C.Y., Chen, C.L., Feng, Z.M., Marshall, A., Bardin, C.W. Biochem. Biophys. Res. Commun. (1988) [Pubmed]
  14. Induction of reproductive tract developmental abnormalities in the male rat by lowering androgen production or action in combination with a low dose of diethylstilbestrol: evidence for importance of the androgen-estrogen balance. Rivas, A., Fisher, J.S., McKinnell, C., Atanassova, N., Sharpe, R.M. Endocrinology (2002) [Pubmed]
  15. New light shed on fluid formation in the seminiferous tubules of the rat. Fisher, D. J. Physiol. (Lond.) (2002) [Pubmed]
  16. Immunoexpression of aquaporin-1 in the efferent ducts of the rat and marmoset monkey during development, its modulation by estrogens, and its possible role in fluid resorption. Fisher, J.S., Turner, K.J., Fraser, H.M., Saunders, P.T., Brown, D., Sharpe, R.M. Endocrinology (1998) [Pubmed]
  17. Evidence for the presence of oxytocin in the ovine epididymis. Knickerbocker, J.J., Sawyer, H.R., Amann, R.P., Tekpetey, F.R., Niswender, G.D. Biol. Reprod. (1988) [Pubmed]
  18. Sertoli-stromal cell tumor of the ovary: immunohistochemical, ultrastructural, and genetic studies. Kato, N., Fukase, M., Ono, I., Matsumoto, K., Okazaki, E., Motoyama, T. Hum. Pathol. (2001) [Pubmed]
  19. Oestrogen in fluid transport in efferent ducts of the male reproductive tract. Hess, R.A. Rev. Reprod. (2000) [Pubmed]
  20. The facilitated diffusion of testosterone into the rete testis of the ram [proceedings]. Main, S.J., Setchell, B.P. J. Physiol. (Lond.) (1978) [Pubmed]
  21. Investigations on the relationship between sperm fertilizing ability and androgen-binding protein in the hypophysectomized, pregnenoloneenolone-injected rat. Anthony, C.T., Danzo, B.J., Orgebin-Crist, M.C. Endocrinology (1984) [Pubmed]
  22. Effects of gonadotropins on androgen levels in rete testis fluid of the ram. Bartke, A., Voglmayr, J.F. Biol. Reprod. (1977) [Pubmed]
  23. Cystic transformation and calcium oxalate deposits in rete testis and efferent ducts in dialysis patients. Nistal, M., Jiménez-Heffernan, J.A., García-Viera, M., Paniagua, R. Hum. Pathol. (1996) [Pubmed]
  24. Aquaporin-1 and -9 are differentially regulated by oestrogen in the efferent ductule epithelium and initial segment of the epididymis. Oliveira, C.A., Carnes, K., França, L.R., Hermo, L., Hess, R.A. Biol. Cell (2005) [Pubmed]
  25. Fas and Fas-ligand expression in seminomatous testes. Braendstrup, O., Bols, B., Jensen, L. APMIS (1999) [Pubmed]
  26. Estrogen receptor alpha has a functional role in the mouse rete testis and efferent ductules. Lee, K.H., Hess, R.A., Bahr, J.M., Lubahn, D.B., Taylor, J., Bunick, D. Biol. Reprod. (2000) [Pubmed]
  27. Co-expression of cytokeratin and vimentin filaments in rete testis and epididymis. An immunohistochemical study. Dinges, H.P., Zatloukal, K., Schmid, C., Mair, S., Wirnsberger, G. Virchows Archiv. A, Pathological anatomy and histopathology. (1991) [Pubmed]
  28. Sertoli cells, proximal convoluted tubules in the kidney, and neurons in the brain contain cyclic protein-2. Zabludoff, S.D., Erickson-Lawrence, M., Wright, W.W. Biol. Reprod. (1990) [Pubmed]
  29. On the regulation of Crisp-1 mRNA expression and protein secretion by luminal factors presented in vivo by microperfusion of the rat proximal caput epididymidis. Turner, T.T., Bomgardner, D. Mol. Reprod. Dev. (2002) [Pubmed]
  30. Immunocytochemical localization of nuclear protamine in boar spermatozoa during epididymal transit. Rodriguez-Martinez, H., Courtens, J.L., Kvist, U., Plöen, L. J. Reprod. Fertil. (1990) [Pubmed]
  31. The mammalian rete testis--a morphological examination. Dym, M. Anat. Rec. (1976) [Pubmed]
  32. A reexamination of rat ductuli efferentes. Lewis-Jones, D.I., Harrison, R.G., Macmillan, E.W. Anat. Rec. (1982) [Pubmed]
WikiGenes - Universities