Gene Review:
Prdx1 - peroxiredoxin 1
Mus musculus
Synonyms:
MSP23, Macrophage 23 kDa stress protein, Msp23, NkefA, OSF-3, ...
- Histone deacetylase inhibitor FK228 activates tumor suppressor Prdx1 with apoptosis induction in esophageal cancer cells. Hoshino, I., Matsubara, H., Hanari, N., Mori, M., Nishimori, T., Yoneyama, Y., Akutsu, Y., Sakata, H., Matsushita, K., Seki, N., Ochiai, T. Clin. Cancer Res. (2005)
- Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression. Neumann, C.A., Krause, D.S., Carman, C.V., Das, S., Dubey, D.P., Abraham, J.L., Bronson, R.T., Fujiwara, Y., Orkin, S.H., Van Etten, R.A. Nature (2003)
- Cloning and characterization of OSF-3, a new member of the MER5 family, expressed in mouse osteoblastic cells. Kawai, S., Takeshita, S., Okazaki, M., Kikuno, R., Kudo, A., Amann, E. J. Biochem. (1994)
- Increased oxidation and degradation of cytosolic proteins in alcohol-exposed mouse liver and hepatoma cells. Kim, B.J., Hood, B.L., Aragon, R.A., Hardwick, J.P., Conrads, T.P., Veenstra, T.D., Song, B.J. Proteomics (2006)
- Increased expression of mitochondrial peroxiredoxin-3 (thioredoxin peroxidase-2) protects cancer cells against hypoxia and drug-induced hydrogen peroxide-dependent apoptosis. Nonn, L., Berggren, M., Powis, G. Mol. Cancer Res. (2003)
- The PAG gene product, a stress-induced protein with antioxidant properties, is an Abl SH3-binding protein and a physiological inhibitor of c-Abl tyrosine kinase activity. Wen, S.T., Van Etten, R.A. Genes Dev. (1997)
- Transcription factor Nrf2 regulates inflammation by mediating the effect of 15-deoxy-Delta(12,14)-prostaglandin j(2). Itoh, K., Mochizuki, M., Ishii, Y., Ishii, T., Shibata, T., Kawamoto, Y., Kelly, V., Sekizawa, K., Uchida, K., Yamamoto, M. Mol. Cell. Biol. (2004)
- Peroxiredoxin II is essential for sustaining life span of erythrocytes in mice. Lee, T.H., Kim, S.U., Yu, S.L., Kim, S.H., Park, d.o. .S., Moon, H.B., Dho, S.H., Kwon, K.S., Kwon, H.J., Han, Y.H., Jeong, S., Kang, S.W., Shin, H.S., Lee, K.K., Rhee, S.G., Yu, D.Y. Blood (2003)
- Cytosolic peroxiredoxin attenuates the activation of Jnk and p38 but potentiates that of Erk in Hela cells stimulated with tumor necrosis factor-alpha. Kang, S.W., Chang, T.S., Lee, T.H., Kim, E.S., Yu, D.Y., Rhee, S.G. J. Biol. Chem. (2004)
- Increased levels of hypoxia-sensitive proteins in allergic airway inflammation. Fajardo, I., Svensson, L., Bucht, A., Pejler, G. Am. J. Respir. Crit. Care Med. (2004)
- Comparative proteomic analysis identifies protein disulfide isomerase and peroxiredoxin 1 as new players involved in embryonic interdigital cell death. Shan, S.W., Tang, M.K., Cai, D.Q., Chui, Y.L., Chow, P.H., Grotewold, L., Lee, K.K. Dev. Dyn. (2005)
- Phorbol ester-dependent activation of peroxiredoxin I gene expression via a protein kinase C, Ras, p38 mitogen-activated protein kinase signaling pathway. Hess, A., Wijayanti, N., Neuschäfer-Rube, A.P., Katz, N., Kietzmann, T., Immenschuh, S. J. Biol. Chem. (2003)
- Pathways of induction of peroxiredoxin I expression in osteoblasts: roles of p38 mitogen-activated protein kinase and protein kinase C. Li, B., Ishii, T., Tan, C.P., Soh, J.W., Goff, S.P. J. Biol. Chem. (2002)
- Histological recovery of the hepatocytes is based on the redox system upregulation in the animal models of mutant superoxide dismutase (SOD)1-linked amyotrophic lateral sclerosis. Kato, M., Kato, S., Abe, Y., Nishino, T., Ohama, E., Aoki, M., Itoyama, Y. Histol. Histopathol. (2006)
- Induction of 1-cys peroxiredoxin expression by oxidative stress in lung epithelial cells. Kim, H.S., Manevich, Y., Feinstein, S.I., Pak, J.H., Ho, Y.S., Fisher, A.B. Am. J. Physiol. Lung Cell Mol. Physiol. (2003)
- Reversible oxidation of the active site cysteine of peroxiredoxins to cysteine sulfinic acid. Immunoblot detection with antibodies specific for the hyperoxidized cysteine-containing sequence. Woo, H.A., Kang, S.W., Kim, H.K., Yang, K.S., Chae, H.Z., Rhee, S.G. J. Biol. Chem. (2003)
- Induction of murine intestinal and hepatic peroxiredoxin MSP23 by dietary butylated hydroxyanisole. Ishii, T., Itoh, K., Akasaka, J., Yanagawa, T., Takahashi, S., Yoshida, H., Bannai, S., Yamamoto, M. Carcinogenesis (2000)
- Contrasting antioxidant and cytotoxic effects of peroxiredoxin I and II in PC12 and NIH3T3 cells. Simzar, S., Ellyin, R., Shau, H., Sarafian, T.A. Neurochem. Res. (2000)
- Inhibition of Mycobacterium tuberculosis AhpD, an element of the peroxiredoxin defense against oxidative stress. Koshkin, A., Zhou, X.T., Kraus, C.N., Brenner, J.M., Bandyopadhyay, P., Kuntz, I.D., Barry, C.E., Ortiz de Montellano, P.R. Antimicrob. Agents Chemother. (2004)
- Mammalian peroxiredoxin isoforms can reduce hydrogen peroxide generated in response to growth factors and tumor necrosis factor-alpha. Kang, S.W., Chae, H.Z., Seo, M.S., Kim, K., Baines, I.C., Rhee, S.G. J. Biol. Chem. (1998)
- Regulation of reactive oxygen species, DNA damage, and c-Myc function by peroxiredoxin 1. Egler, R.A., Fernandes, E., Rothermund, K., Sereika, S., de Souza-Pinto, N., Jaruga, P., Dizdaroglu, M., Prochownik, E.V. Oncogene (2005)
- Pag, a putative tumor suppressor, interacts with the Myc Box II domain of c-Myc and selectively alters its biological function and target gene expression. Mu, Z.M., Yin, X.Y., Prochownik, E.V. J. Biol. Chem. (2002)
- Cloning and expression of mouse peroxiredoxin I in IEC-6 Cells. Zhang, B., Su, Y.P., Wang, T., Wang, F.C., Ai, G.P., Xu, H., Wang, J.P., Huang, Y.S., Jiang, J.X. World J. Gastroenterol. (2004)