The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

Gh1  -  growth hormone 1

Rattus norvegicus

Synonyms: Gh, Growth hormone, RNGHGP, Somatotropin
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Gh1


Psychiatry related information on Gh1


High impact information on Gh1


Chemical compound and disease context of Gh1


Biological context of Gh1


Anatomical context of Gh1


Associations of Gh1 with chemical compounds


Regulatory relationships of Gh1


Other interactions of Gh1


Analytical, diagnostic and therapeutic context of Gh1


  1. Growth hormone attenuates early left ventricular remodeling and improves cardiac function in rats with large myocardial infarction. Cittadini, A., Grossman, J.D., Napoli, R., Katz, S.E., Strömer, H., Smith, R.J., Clark, R., Morgan, J.P., Douglas, P.S. J. Am. Coll. Cardiol. (1997) [Pubmed]
  2. Growth hormone-regulated intracellular signaling in UMR 106 osteosarcoma cells. Morales, O., Lindgren, U., Haldosén, L.A. J. Bone Miner. Res. (2000) [Pubmed]
  3. Growth hormone-mediated regulation of insulin-like growth factor I promoter activity in C6 glioma cells. Benbassat, C., Shoba, L.N., Newman, M., Adamo, M.L., Frank, S.J., Lowe, W.L. Endocrinology (1999) [Pubmed]
  4. Growth hormone therapy during neonatal hypoxia in rats: body composition, bone mineral density, and insulin-like growth factor-1 expression. Raff, H., Bruder, E.D., Jankowski, B., Oaks, M.K., Colman, R.J. Endocrine (2001) [Pubmed]
  5. Growth hormone is secreted by ectopic pituitary grafts and stimulates maternal behavior in rats. Bridges, R.S., Millard, W.J. Hormones and behavior. (1988) [Pubmed]
  6. Growth hormone effects on sleep and wakefulness in the rat. Drucker-Colín, R.R., Spanis, C.W., Hunyadi, J., Sassin, J.F., McGaugh, J.L. Neuroendocrinology (1975) [Pubmed]
  7. Growth restoration of insulin-deficient diabetic rats by recombinant human insulin-like growth factor I. Scheiwiller, E., Guler, H.P., Merryweather, J., Scandella, C., Maerki, W., Zapf, J., Froesch, E.R. Nature (1986) [Pubmed]
  8. Growth hormone and the insulin-like growth factor system in myogenesis. Florini, J.R., Ewton, D.Z., Coolican, S.A. Endocr. Rev. (1996) [Pubmed]
  9. Growth hormone-releasing factor stimulates pancreatic enzyme secretion. Pandol, S.J., Seifert, H., Thomas, M.W., Rivier, J., Vale, W. Science (1984) [Pubmed]
  10. Growth hormone stimulates longitudinal bone growth directly. Isaksson, O.G., Jansson, J.O., Gause, I.A. Science (1982) [Pubmed]
  11. Growth hormone and bile acid synthesis. Key role for the activity of hepatic microsomal cholesterol 7alpha-hydroxylase in the rat. Rudling, M., Parini, P., Angelin, B. J. Clin. Invest. (1997) [Pubmed]
  12. 5-azacytidine-induced alterations in the GH12C1 cells: effects on cellular morphology, chromosome structure, DNA and protein synthesis. Parrow, V.C., Aleström, P., Gautvik, K.M. J. Cell. Sci. (1989) [Pubmed]
  13. Growth hormone, somatomedin and cartilage sulfation in failure of catch-up growth after propylthiouracil-induced hypothyroidism in the rat. Mosier, H.D., Dearden, L.C., Jansons, R.A., Hill, R.R. Endocrinology (1977) [Pubmed]
  14. Growth hormone (GH) modulates insulin-like growth factor I (IGF-I) and type I IGF receptor mRNA levels in the ovary of prepubertal GH-deficient rats. Malozowski, S., Parmer, T.G., Trojan, S., Merriam, G.R., Gibori, G., Roberts, C.T., LeRoith, D., Werner, H., Zilberstein, M. Eur. J. Endocrinol. (1995) [Pubmed]
  15. Growth hormone alone or combined with metoprolol preserves cardiac function after myocardial infarction in rats. Bollano, E., Bergh, C.H., Kjellström, C., Omerovic, E., Kujacic, V., Caidahl, K., Bengtsson, B.A., Waagstein, F., Isgaard, J. Eur. J. Heart Fail. (2001) [Pubmed]
  16. Growth hormone induces tyrosine phosphorylation of annexin I in rat osteosarcoma cells. Salles, J.P., Netelenbos, J.C., Slootweg, M.C. Endocrinology (1996) [Pubmed]
  17. Growth hormone-induced differential desensitization of STAT5, ERK, and Akt phosphorylation. Ji, S., Frank, S.J., Messina, J.L. J. Biol. Chem. (2002) [Pubmed]
  18. Growth hormone (GH) deprivation induced by passive immunization against rat GH-releasing factor does not disturb the course of sexual maturation and fertility in the female rat. Gruaz, N.M., Arsenijevic, Y., Wehrenberg, W.B., Sizonenko, P.C., Aubert, M.L. Endocrinology (1994) [Pubmed]
  19. Growth hormone stimulates granulation tissue formation and insulin-like growth factor-I gene expression in wound chambers in the rat. Steenfos, H.H., Jansson, J.O. J. Endocrinol. (1992) [Pubmed]
  20. Dynamic studies of growth hormone and prolactin secretion in the female rat. Saunders, A., Terry, L.C., Audet, J., Brazeau, P., Martin, J.B. Neuroendocrinology (1976) [Pubmed]
  21. Growth hormone in vivo potentiates the stimulatory effect of insulin-like growth factor-1 in vitro on colony formation of epiphyseal chondrocytes isolated from hypophysectomized rats. Lindahl, A., Isgaard, J., Isaksson, O.G. Endocrinology (1987) [Pubmed]
  22. Growth hormone induces in vitro maturation of follicle- and cumulus-enclosed rat oocytes. Apa, R., Lanzone, A., Miceli, F., Mastrandrea, M., Caruso, A., Mancuso, S., Canipari, R. Mol. Cell. Endocrinol. (1994) [Pubmed]
  23. Growth hormone, insulin-like growth factor-1, and the insulin-like growth factor binding proteins in rats maintaining reduced body protein following lesions of the lateral hypothalamus. Hinton, P.S., Hirvonen, M.D., Ney, D.M., Keesey, R.E. Physiol. Behav. (2000) [Pubmed]
  24. Possible effects of growth hormone on development of acute lymphoblastic leukaemia. Rogers, P.C., Komp, D., Rogol, A., Sabio, H. Lancet (1977) [Pubmed]
  25. Growth hormone induces multiplication of the slowly cycling germinal cells of the rat tibial growth plate. Ohlsson, C., Nilsson, A., Isaksson, O., Lindahl, A. Proc. Natl. Acad. Sci. U.S.A. (1992) [Pubmed]
  26. Cardiac resistance to growth hormone in uremia. Zheng, Z., Sun, D.F., Tummala, P., Rabkin, R. Kidney Int. (2005) [Pubmed]
  27. Growth hormone regulation of male-specific rat liver P450s 2A2 and 3A2: induction by intermittent growth hormone pulses in male but not female rats rendered growth hormone deficient by neonatal monosodium glutamate. Waxman, D.J., Ram, P.A., Pampori, N.A., Shapiro, B.H. Mol. Pharmacol. (1995) [Pubmed]
  28. Growth hormone regulation in primary fetal and neonatal rat pituitary cell cultures: the role of thyroid hormone. Ezzat, S., Laks, D., Oster, J., Melmed, S. Endocrinology (1991) [Pubmed]
  29. Growth hormone secretion by cultured rat anterior pituitary cells. Effects of culture conditions and dexamethasone. Oosterom, R., Verleun, T., Zuiderwijk, J., Lamberts, S.W. Endocrinology (1983) [Pubmed]
  30. Hormonal regulation of renal ornithine decarboxylase activity in the rat. Nicholson, W.E., Levine, J.H., Orth, D.N. Endocrinology (1976) [Pubmed]
  31. Growth hormone regulates the abundance of insulin-like growth factor I RNA in adult rat liver. Roberts, C.T., Brown, A.L., Graham, D.E., Seelig, S., Berry, S., Gabbay, K.H., Rechler, M.M. J. Biol. Chem. (1986) [Pubmed]
  32. Growth hormone rapidly activates rat serine protease inhibitor 2.1 gene transcription and induces a DNA-binding activity distinct from those of Stat1, -3, and -4. Thomas, M.J., Gronowski, A.M., Berry, S.A., Bergad, P.L., Rotwein, P. Mol. Cell. Biol. (1995) [Pubmed]
  33. Growth hormone stimulates the tyrosine phosphorylation of the insulin receptor substrate-1 and its association with phosphatidylinositol 3-kinase in primary adipocytes. Ridderstråle, M., Degerman, E., Tornqvist, H. J. Biol. Chem. (1995) [Pubmed]
  34. Growth hormone promotes early initiation of hepatocyte growth factor gene expression in the liver of hypophysectomized rats after partial hepatectomy. Ekberg, S., Luther, M., Nakamura, T., Jansson, J.O. J. Endocrinol. (1992) [Pubmed]
  35. Growth hormone (GH) stimulates protein synthesis in cells transfected with GH receptor complementary DNA. Emtner, M., Mathews, L.S., Norstedt, G. Mol. Endocrinol. (1990) [Pubmed]
  36. 5-bromodeoxyuridine-induced amplification of prolactin gene in GH cells is an extrachromosomal event. Wilson, D.J., Hanes, S.D., Pichler, M.H., Biswas, D.K. Biochemistry (1983) [Pubmed]
  37. Accumulation of synaptosomal-associated protein of 25 kDa (SNAP-25) and other proteins associated with the secretory pathway in GH4C1 cells upon treatment with estradiol, insulin, and epidermal growth factor. Lee, M.S., Zhu, Y.L., Sun, Z., Rhee, H., Jeromin, A., Roder, J., Dannies, P.S. Endocrinology (2000) [Pubmed]
  38. Growth hormone activity in mitochondria depends on GH receptor Box 1 and involves caveolar pathway targeting. Perret-Vivancos, C., Abbate, A., Ardail, D., Raccurt, M., Usson, Y., Lobie, P.E., Morel, G. Exp. Cell Res. (2006) [Pubmed]
  39. Growth hormone release induced by growth hormone-releasing hexapeptide is not mediated by thyrotropin-releasing hormone in neonatal rats. Kacsóh, B., Kacsóh, G., Guzzardo, M.B., Black, A.C., Bisat, T. Pediatr. Res. (1997) [Pubmed]
  40. Growth hormone-mediated breakdown of body fat: insulin and leptin responses to GH are modulated by diet composition and caloric intake in old rats. Malmlöf, K., Johansen, T. Horm. Metab. Res. (2003) [Pubmed]
  41. Growth hormone-mediated janus associated kinase-signal transducers and activators of transcription signaling in the growth hormone-resistant potassium-deficient rat. Schaefer, F., Yoon, S.A., Nouri, P., Tsao, T., Tummala, P., Deng, E., Rabkin, R. J. Am. Soc. Nephrol. (2004) [Pubmed]
  42. Pulsatile growth hormone and prolactin: effects of (+) butaclamol, a dopamine receptor blocking agent. Willoughby, J.O., Brazeau, P., Martin, J.B. Endocrinology (1977) [Pubmed]
  43. Correlation between the biological and immunological activities of growth hormone circulating in rats bearing MtTW15 tumors. Stewart, J.K., Reagan, C.R., Kostyo, J.L. Endocrinology (1977) [Pubmed]
  44. Stereological and biochemical analysis of prolactin and growth hormone secreting rat pituitary cells in culture. Stereology combined with non-parametrical statistics. Fossum, S., Gautvik, K.M. Cell Tissue Res. (1977) [Pubmed]
WikiGenes - Universities