Gene Review:
GIT1 - G protein-coupled receptor kinase...
Homo sapiens
Synonyms:
ARF GAP GIT1, ARF GTPase-activating protein GIT1, CAT-1, CAT1, Cool-associated and tyrosine-phosphorylated protein 1, ...
- Catalase transcript accumulation in response to dehydration and osmotic stress in leaves of maize viviparous mutants. Guan, L.M., Scandalios, J.G. Redox Rep. (2000)
- Dose of cat (Felis domesticus) allergen 1 (Fel d 1) that induces asthma. Van Metre, T.E., Marsh, D.G., Adkinson, N.F., Fish, J.E., Kagey-Sobotka, A., Norman, P.S., Radden, E.B., Rosenberg, G.L. J. Allergy Clin. Immunol. (1986)
- A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease. Goehler, H., Lalowski, M., Stelzl, U., Waelter, S., Stroedicke, M., Worm, U., Droege, A., Lindenberg, K.S., Knoblich, M., Haenig, C., Herbst, M., Suopanki, J., Scherzinger, E., Abraham, C., Bauer, B., Hasenbank, R., Fritzsche, A., Ludewig, A.H., Büssow, K., Buessow, K., Coleman, S.H., Gutekunst, C.A., Landwehrmeyer, B.G., Lehrach, H., Wanker, E.E. Mol. Cell (2004)
- Synapse formation is regulated by the signaling adaptor GIT1. Zhang, H., Webb, D.J., Asmussen, H., Horwitz, A.F. J. Cell Biol. (2003)
- The GIT-associated kinase PAK targets to the centrosome and regulates Aurora-A. Zhao, Z.S., Lim, J.P., Ng, Y.W., Lim, L., Manser, E. Mol. Cell (2005)
- GIT2 represses Crk- and Rac1-regulated cell spreading and Cdc42-mediated focal adhesion turnover. Frank, S.R., Adelstein, M.R., Hansen, S.H. EMBO J. (2006)
- Thyrotropin receptor trafficking relies on the hScrib-betaPIX-GIT1-ARF6 pathway. Lahuna, O., Quellari, M., Achard, C., Nola, S., Méduri, G., Navarro, C., Vitale, N., Borg, J.P., Misrahi, M. EMBO J. (2005)
- Coupling of PAK-interacting exchange factor PIX to GIT1 promotes focal complex disassembly. Zhao, Z.S., Manser, E., Loo, T.H., Lim, L. Mol. Cell. Biol. (2000)
- The GIT family of ADP-ribosylation factor GTPase-activating proteins. Functional diversity of GIT2 through alternative splicing. Premont, R.T., Claing, A., Vitale, N., Perry, S.J., Lefkowitz, R.J. J. Biol. Chem. (2000)
- The GIT family of proteins forms multimers and associates with the presynaptic cytomatrix protein Piccolo. Kim, S., Ko, J., Shin, H., Lee, J.R., Lim, C., Han, J.H., Altrock, W.D., Garner, C.C., Gundelfinger, E.D., Premont, R.T., Kaang, B.K., Kim, E. J. Biol. Chem. (2003)
- GIT1 mediates thrombin signaling in endothelial cells: role in turnover of RhoA-type focal adhesions. van Nieuw Amerongen, G.P., Natarajan, K., Yin, G., Hoefen, R.J., Osawa, M., Haendeler, J., Ridley, A.J., Fujiwara, K., van Hinsbergh, V.W., Berk, B.C. Circ. Res. (2004)
- Characterization of the endogenous GIT1-betaPIX complex, and identification of its association to membranes. Botrugno, O.A., Paris, S., Za, L., Gualdoni, S., Cattaneo, A., Bachi, A., de Curtis, I. Eur. J. Cell Biol. (2006)
- beta2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein. Premont, R.T., Claing, A., Vitale, N., Freeman, J.L., Pitcher, J.A., Patton, W.A., Moss, J., Vaughan, M., Lefkowitz, R.J. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Identification of GIT1/Cat-1 as a substrate molecule of protein tyrosine phosphatase zeta /beta by the yeast substrate-trapping system. Kawachi, H., Fujikawa, A., Maeda, N., Noda, M. Proc. Natl. Acad. Sci. U.S.A. (2001)
- GIT1 is a scaffold for ERK1/2 activation in focal adhesions. Yin, G., Zheng, Q., Yan, C., Berk, B.C. J. Biol. Chem. (2005)
- GIT1 mediates Src-dependent activation of phospholipase Cgamma by angiotensin II and epidermal growth factor. Haendeler, J., Yin, G., Hojo, Y., Saito, Y., Melaragno, M., Yan, C., Sharma, V.K., Heller, M., Aebersold, R., Berk, B.C. J. Biol. Chem. (2003)
- Phosphorylation of serine 709 in GIT1 regulates protrusive activity in cells. Webb, D.J., Kovalenko, M., Whitmore, L., Horwitz, A.F. Biochem. Biophys. Res. Commun. (2006)
- Association of the kinesin motor KIF1A with the multimodular protein liprin-alpha. Shin, H., Wyszynski, M., Huh, K.H., Valtschanoff, J.G., Lee, J.R., Ko, J., Streuli, M., Weinberg, R.J., Sheng, M., Kim, E. J. Biol. Chem. (2003)
- Transport and metabolism of glycerophosphodiesters produced through phospholipid deacylation. Patton-Vogt, J. Biochim. Biophys. Acta (2007)
- Hic-5 interacts with GIT1 with a different binding mode from paxillin. Nishiya, N., Shirai, T., Suzuki, W., Nose, K. J. Biochem. (2002)
- Interaction between liprin-alpha and GIT1 is required for AMPA receptor targeting. Ko, J., Kim, S., Valtschanoff, J.G., Shin, H., Lee, J.R., Sheng, M., Premont, R.T., Weinberg, R.J., Kim, E. J. Neurosci. (2003)
- Multiple endocytic pathways of G protein-coupled receptors delineated by GIT1 sensitivity. Claing, A., Perry, S.J., Achiriloaie, M., Walker, J.K., Albanesi, J.P., Lefkowitz, R.J., Premont, R.T. Proc. Natl. Acad. Sci. U.S.A. (2000)
- Regulation of neuroendocrine exocytosis by the ARF6 GTPase-activating protein GIT1. Meyer, M.Z., Déliot, N., Chasserot-Golaz, S., Premont, R.T., Bader, M.F., Vitale, N. J. Biol. Chem. (2006)
- GIT1 functions in a motile, multi-molecular signaling complex that regulates protrusive activity and cell migration. Manabe, R., Kovalenko, M., Webb, D.J., Horwitz, A.R. J. Cell. Sci. (2002)
- The phosphotyrosine peptide binding specificity of Nck1 and Nck2 Src homology 2 domains. Frese, S., Schubert, W.D., Findeis, A.C., Marquardt, T., Roske, Y.S., Stradal, T.E., Heinz, D.W. J. Biol. Chem. (2006)
- Molecular weight determination of allergen extracts and isolation of allergenic molecules by high-performance liquid chromatography. Wahl, R., Meineke, D., Maasch, H.J. J. Chromatogr. (1987)