Gene Review:
Slc40a1 - solute carrier family 40 (iron-regulated...
Mus musculus
Synonyms:
Dusg, FPN1, Ferroportin-1, Fpn1, IREG1, ...
- Iron overload in adult Hfe-deficient mice independent of changes in the steady-state expression of the duodenal iron transporters DMT1 and Ireg1/ferroportin. Herrmann, T., Muckenthaler, M., van der Hoeven, F., Brennan, K., Gehrke, S.G., Hubert, N., Sergi, C., Gröne, H.J., Kaiser, I., Gosch, I., Volkmann, M., Riedel, H.D., Hentze, M.W., Stewart, A.F., Stremmel, W. J. Mol. Med. (2004)
- Expression of the iron transporter ferroportin in synaptic vesicles and the blood-brain barrier. Wu, L.J., Leenders, A.G., Cooperman, S., Meyron-Holtz, E., Smith, S., Land, W., Tsai, R.Y., Berger, U.V., Sheng, Z.H., Rouault, T.A. Brain Res. (2004)
- The molecular circuitry regulating the switch between iron deficiency and overload in mice. Mok, H., Mlodnicka, A.E., Hentze, M.W., Muckenthaler, M., Schumacher, A. J. Biol. Chem. (2006)
- Expression of iron absorption genes in mouse large intestine. Takeuchi, K., Bjarnason, I., Laftah, A.H., Latunde-Dada, G.O., Simpson, R.J., McKie, A.T. Scand. J. Gastroenterol. (2005)
- Lack of mitochondrial trifunctional protein in mice causes neonatal hypoglycemia and sudden death. Ibdah, J.A., Paul, H., Zhao, Y., Binford, S., Salleng, K., Cline, M., Matern, D., Bennett, M.J., Rinaldo, P., Strauss, A.W. J. Clin. Invest. (2001)
- Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter. Donovan, A., Brownlie, A., Zhou, Y., Shepard, J., Pratt, S.J., Moynihan, J., Paw, B.H., Drejer, A., Barut, B., Zapata, A., Law, T.C., Brugnara, C., Lux, S.E., Pinkus, G.S., Pinkus, J.L., Kingsley, P.D., Palis, J., Fleming, M.D., Andrews, N.C., Zon, L.I. Nature (2000)
- A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation. McKie, A.T., Marciani, P., Rolfs, A., Brennan, K., Wehr, K., Barrow, D., Miret, S., Bomford, A., Peters, T.J., Farzaneh, F., Hediger, M.A., Hentze, M.W., Simpson, R.J. Mol. Cell (2000)
- A mammalian lysosomal membrane protein confers multidrug resistance upon expression in Saccharomyces cerevisiae. Hogue, D.L., Kerby, L., Ling, V. J. Biol. Chem. (1999)
- Cross-reactivity between haptenic muramyl di- or tripeptide derivatives and Mycobacterium bovis BCG: potential application for enhancing tumor immunity. Kosugi, A., Shima, J., Sano, H., Ogata, M., Kusama, T., Fujiwara, H., Hamaoka, T. Infect. Immun. (1986)
- The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis. Donovan, A., Lima, C.A., Pinkus, J.L., Pinkus, G.S., Zon, L.I., Robine, S., Andrews, N.C. Cell metabolism. (2005)
- Disruption of ferroportin 1 regulation causes dynamic alterations in iron homeostasis and erythropoiesis in polycythaemia mice. Mok, H., Jelinek, J., Pai, S., Cattanach, B.M., Prchal, J.T., Youssoufian, H., Schumacher, A. Development (2004)
- Systemic regulation of Hephaestin and Ireg1 revealed in studies of genetic and nutritional iron deficiency. Chen, H., Su, T., Attieh, Z.K., Fox, T.C., McKie, A.T., Anderson, G.J., Vulpe, C.D. Blood (2003)
- Hepatic expression of hemochromatosis genes in two mouse strains after phlebotomy and iron overload. Bondi, A., Valentino, P., Daraio, F., Porporato, P., Gramaglia, E., Carturan, S., Gottardi, E., Camaschella, C., Roetto, A. Haematologica (2005)
- Iron loading and erythrophagocytosis increase ferroportin 1 (FPN1) expression in J774 macrophages. Knutson, M.D., Vafa, M.R., Haile, D.J., Wessling-Resnick, M. Blood (2003)
- Regulation of reticuloendothelial iron transporter MTP1 (Slc11a3) by inflammation. Yang, F., Liu, X.B., Quinones, M., Melby, P.C., Ghio, A., Haile, D.J. J. Biol. Chem. (2002)
- Iron homeostasis in neuronal cells: a role for IREG1. Aguirre, P., Mena, N., Tapia, V., Arredondo, M., Núñez, M.T. BMC neuroscience [electronic resource]. (2005)
- Liver microsomal triglyceride transfer protein is involved in hepatitis C liver steatosis. Mirandola, S., Realdon, S., Iqbal, J., Gerotto, M., Dal Pero, F., Bortoletto, G., Marcolongo, M., Vario, A., Datz, C., Hussain, M.M., Alberti, A. Gastroenterology (2006)
- Glycosylphosphatidylinositol-anchored ceruloplasmin is required for iron efflux from cells in the central nervous system. Jeong, S.Y., David, S. J. Biol. Chem. (2003)
- Mislocalisation of hephaestin, a multicopper ferroxidase involved in basolateral intestinal iron transport, in the sex linked anaemia mouse. Kuo, Y.M., Su, T., Chen, H., Attieh, Z., Syed, B.A., McKie, A.T., Anderson, G.J., Gitschier, J., Vulpe, C.D. Gut (2004)
- A compartmental model of iron regulation in the mouse. Lao, B.J., Kamei, D.T. J. Theor. Biol. (2006)
- Distinct requirements for Hfe in basal and induced hepcidin levels in iron overload and inflammation. Constante, M., Jiang, W., Wang, D., Raymond, V.A., Bilodeau, M., Santos, M.M. Am. J. Physiol. Gastrointest. Liver Physiol. (2006)
- Immunolocalization and regulation of iron handling proteins ferritin and ferroportin in the retina. Hahn, P., Dentchev, T., Qian, Y., Rouault, T., Harris, Z.L., Dunaief, J.L. Mol. Vis. (2004)
- Apical location of ferroportin 1 in airway epithelia and its role in iron detoxification in the lung. Yang, F., Haile, D.J., Wang, X., Dailey, L.A., Stonehuerner, J.G., Ghio, A.J. Am. J. Physiol. Lung Cell Mol. Physiol. (2005)
- Assignment of Slc11a3 to mouse chromosome 1 band 1B and SLC11A3 to human chromosome 2q32 by in situ hybridization. Haile, D.J. Cytogenet. Cell Genet. (2000)