Gene Review:
PRKAB1 - protein kinase, AMP-activated, beta 1 non...
Homo sapiens
Synonyms:
5'-AMP-activated protein kinase subunit beta-1, AMPK, AMPK subunit beta-1, AMPKb, HAMPKb
- Adiponectin and adiponectin receptors. Kadowaki, T., Yamauchi, T. Endocr. Rev. (2005)
- Combination of 5-fluorouracil and genistein induces apoptosis synergistically in chemo-resistant cancer cells through the modulation of AMPK and COX-2 signaling pathways. Hwang, J.T., Ha, J., Park, O.J. Biochem. Biophys. Res. Commun. (2005)
- AICAR, an activator of AMP-activated protein kinase, down-regulates the insulin receptor expression in HepG2 cells. Nakamaru, K., Matsumoto, K., Taguchi, T., Suefuji, M., Murata, Y., Igata, M., Kawashima, J., Kondo, T., Motoshima, H., Tsuruzoe, K., Miyamura, N., Toyonaga, T., Araki, E. Biochem. Biophys. Res. Commun. (2005)
- Minireview: the AMP-activated protein kinase cascade: the key sensor of cellular energy status. Hardie, D.G. Endocrinology (2003)
- AMPK integrates nutrient and hormonal signals to regulate food intake and energy balance through effects in the hypothalamus and peripheral tissues. Xue, B., Kahn, B.B. J. Physiol. (Lond.) (2006)
- C75, a fatty acid synthase inhibitor, reduces food intake via hypothalamic AMP-activated protein kinase. Kim, E.K., Miller, I., Aja, S., Landree, L.E., Pinn, M., McFadden, J., Kuhajda, F.P., Moran, T.H., Ronnett, G.V. J. Biol. Chem. (2004)
- Sequential changes in the signal transduction responses of skeletal muscle following food deprivation. de Lange, P., Farina, P., Moreno, M., Ragni, M., Lombardi, A., Silvestri, E., Burrone, L., Lanni, A., Goglia, F. FASEB J. (2006)
- TSC2 Integrates Wnt and Energy Signals via a Coordinated Phosphorylation by AMPK and GSK3 to Regulate Cell Growth. Inoki, K., Ouyang, H., Zhu, T., Lindvall, C., Wang, Y., Zhang, X., Yang, Q., Bennett, C., Harada, Y., Stankunas, K., Wang, C.Y., He, X., Macdougald, O.A., You, M., Williams, B.O., Guan, K.L. Cell (2006)
- Glucose metabolism and cancer. Shaw, R.J. Curr. Opin. Cell Biol. (2006)
- Regulation of the energy sensor AMP-activated protein kinase by antigen receptor and Ca2+ in T lymphocytes. Tamás, P., Hawley, S.A., Clarke, R.G., Mustard, K.J., Green, K., Hardie, D.G., Cantrell, D.A. J. Exp. Med. (2006)
- AMP-activated protein kinase--development of the energy sensor concept. Hardie, D.G., Hawley, S.A., Scott, J.W. J. Physiol. (Lond.) (2006)
- Effects of adenosine on myocardial glucose and palmitate metabolism after transient ischemia: role of 5'-AMP-activated protein kinase. Jaswal, J.S., Gandhi, M., Finegan, B.A., Dyck, J.R., Clanachan, A.S. Am. J. Physiol. Heart Circ. Physiol. (2006)
- AMP-activated protein kinase: role in metabolism and therapeutic implications. Schimmack, G., Defronzo, R.A., Musi, N. Diabetes, obesity & metabolism. (2006)
- Inhibition of lipid synthesis through activation of AMP kinase: an additional mechanism for the hypolipidemic effects of berberine. Brusq, J.M., Ancellin, N., Grondin, P., Guillard, R., Martin, S., Saintillan, Y., Issandou, M. J. Lipid Res. (2006)
- Long-term activation of adenosine monophosphate-activated protein kinase attenuates pressure-overload-induced cardiac hypertrophy. Li, H.L., Yin, R., Chen, D., Liu, D., Wang, D., Yang, Q., Dong, Y.G. J. Cell. Biochem. (2007)
- Haplotype structures and large-scale association testing of the 5' AMP-activated protein kinase genes PRKAA2, PRKAB1, and PRKAB1 with type 2 diabetes. Sun, M.W., Lee, J.Y., de Bakker, P.I., Burtt, N.P., Almgren, P., Råstam, L., Tuomi, T., Gaudet, D., Daly, M.J., Hirschhorn, J.N., Altshuler, D., Groop, L., Florez, J.C. Diabetes (2006)
- Mammalian AMP-activated protein kinase subfamily. Stapleton, D., Mitchelhill, K.I., Gao, G., Widmer, J., Michell, B.J., Teh, T., House, C.M., Fernandez, C.S., Cox, T., Witters, L.A., Kemp, B.E. J. Biol. Chem. (1996)
- Circulating adiponectin and expression of adiponectin receptors in human skeletal muscle: associations with metabolic parameters and insulin resistance and regulation by physical training. Blüher, M., Bullen, J.W., Lee, J.H., Kralisch, S., Fasshauer, M., Klöting, N., Niebauer, J., Schön, M.R., Williams, C.J., Mantzoros, C.S. J. Clin. Endocrinol. Metab. (2006)
- Predominant {alpha}2/{beta}2/{gamma}3 AMPK activation during exercise in human skeletal muscle. Birk, J.B., Wojtaszewski, J.F. J. Physiol. (Lond.) (2006)
- AMPK regulation of the growth of cultured human keratinocytes. Saha, A.K., Persons, K., Safer, J.D., Luo, Z., Holick, M.F., Ruderman, N.B. Biochem. Biophys. Res. Commun. (2006)
- Obesity and the role of adipose tissue in inflammation and metabolism. Greenberg, A.S., Obin, M.S. Am. J. Clin. Nutr. (2006)
- Functions of AMP-activated protein kinase in adipose tissue. Daval, M., Foufelle, F., Ferré, P. J. Physiol. (Lond.) (2006)
- Non-catalytic beta- and gamma-subunit isoforms of the 5'-AMP-activated protein kinase. Gao, G., Fernandez, C.S., Stapleton, D., Auster, A.S., Widmer, J., Dyck, J.R., Kemp, B.E., Witters, L.A. J. Biol. Chem. (1996)
- Different effects of adiponectin isoforms in human monocytic cells. Neumeier, M., Weigert, J., Schäffler, A., Wehrwein, G., Müller-Ladner, U., Schölmerich, J., Wrede, C., Buechler, C. J. Leukoc. Biol. (2006)
- Glycogen debranching enzyme association with beta-subunit regulates AMP-activated protein kinase activity. Sakoda, H., Fujishiro, M., Fujio, J., Shojima, N., Ogihara, T., Kushiyama, A., Fukushima, Y., Anai, M., Ono, H., Kikuchi, M., Horike, N., Viana, A.Y., Uchijima, Y., Kurihara, H., Asano, T. Am. J. Physiol. Endocrinol. Metab. (2005)
- Adenosine 5'-Monophosphate Kinase-Activated Protein Kinase (PRKA) Activators Delay Meiotic Resumption in Porcine Oocytes. Mayes, M.A., Laforest, M.F., Guillemette, C., Gilchrist, R.B., Richard, F.J. Biol. Reprod. (2007)
- Identification of a novel AMP-activated protein kinase beta subunit isoform that is highly expressed in skeletal muscle. Thornton, C., Snowden, M.A., Carling, D. J. Biol. Chem. (1998)
- Normal mammalian skeletal muscle and its phenotypic plasticity. Hoppeler, H., Flück, M. J. Exp. Biol. (2002)
- More TORC for the gluconeogenic engine. Cheng, A., Saltiel, A.R. Bioessays (2006)
- Selenium Regulates Cyclooxygenase-2 and Extracellular Signal-Regulated Kinase Signaling Pathways by Activating AMP-Activated Protein Kinase in Colon Cancer Cells. Hwang, J.T., Kim, Y.M., Surh, Y.J., Baik, H.W., Lee, S.K., Ha, J., Park, O.J. Cancer Res. (2006)
- Characterization of AMP-activated protein kinase beta and gamma subunits. Assembly of the heterotrimeric complex in vitro. Woods, A., Cheung, P.C., Smith, F.C., Davison, M.D., Scott, J., Beri, R.K., Carling, D. J. Biol. Chem. (1996)
- AMPK control of myocardial fatty acid metabolism fluctuates with the intensity of insulin-deficient diabetes. Kewalramani, G., An, D., Kim, M.S., Ghosh, S., Qi, D., Abrahani, A., Pulinilkunnil, T., Sharma, V., Wambolt, R.B., Allard, M.F., Innis, S.M., Rodrigues, B. J. Mol. Cell. Cardiol. (2007)
- LKB1, an upstream AMPK kinase, regulates glucose and lipid metabolism in cultured liver and muscle cells. Imai, K., Inukai, K., Ikegami, Y., Awata, T., Katayama, S. Biochem. Biophys. Res. Commun. (2006)