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Gene Review

Retn  -  resistin

Mus musculus

Synonyms: ADSF, Adipose tissue-specific secretory factor, Adipose-specific cysteine-rich secreted protein A12-alpha, Cysteine-rich secreted protein FIZZ3, Fizz3, ...
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Analytical, diagnostic and therapeutic context of Retn


  1. Resistin/ADSF/FIZZ3 in obesity and diabetes. Sul, H.S. Trends Endocrinol. Metab. (2004) [Pubmed]
  2. Regulation of resistin expression and circulating levels in obesity, diabetes, and fasting. Rajala, M.W., Qi, Y., Patel, H.R., Takahashi, N., Banerjee, R., Pajvani, U.B., Sinha, M.K., Gingerich, R.L., Scherer, P.E., Ahima, R.S. Diabetes (2004) [Pubmed]
  3. Cell type-specific expression and coregulation of murine resistin and resistin-like molecule-alpha in adipose tissue. Rajala, M.W., Lin, Y., Ranalletta, M., Yang, X.M., Qian, H., Gingerich, R., Barzilai, N., Scherer, P.E. Mol. Endocrinol. (2002) [Pubmed]
  4. IGF-I downregulates resistin gene expression and protein secretion. Chen, Y.H., Hung, P.F., Kao, Y.H. Am. J. Physiol. Endocrinol. Metab. (2005) [Pubmed]
  5. Weight loss in tumour-bearing mice is not associated with changes in resistin gene expression in white adipose tissue. Gómez-Ambrosi, J., Zabalegui, N., Bing, C., Tisdale, M.J., Trayhurn, P., Williams, G. Horm. Metab. Res. (2002) [Pubmed]
  6. Pituitary resistin gene expression: effects of age, gender and obesity. Morash, B.A., Ur, E., Wiesner, G., Roy, J., Wilkinson, M. Neuroendocrinology (2004) [Pubmed]
  7. IL-31-IL-31R interactions negatively regulate type 2 inflammation in the lung. Perrigoue, J.G., Li, J., Zaph, C., Goldschmidt, M., Scott, P., de Sauvage, F.J., Pearce, E.J., Ghilardi, N., Artis, D. J. Exp. Med. (2007) [Pubmed]
  8. Adenovirus-mediated chronic "hyper-resistinemia" leads to in vivo insulin resistance in normal rats. Satoh, H., Nguyen, M.T., Miles, P.D., Imamura, T., Usui, I., Olefsky, J.M. J. Clin. Invest. (2004) [Pubmed]
  9. Role of resistin in diet-induced hepatic insulin resistance. Muse, E.D., Obici, S., Bhanot, S., Monia, B.P., McKay, R.A., Rajala, M.W., Scherer, P.E., Rossetti, L. J. Clin. Invest. (2004) [Pubmed]
  10. Changes in glycemia by leptin administration or high- fat feeding in rodent models of obesity/type 2 diabetes suggest a link between resistin expression and control of glucose homeostasis. Asensio, C., Cettour-Rose, P., Theander-Carrillo, C., Rohner-Jeanrenaud, F., Muzzin, P. Endocrinology (2004) [Pubmed]
  11. Effect of metformin on adipose tissue resistin expression in db/db mice. Fujita, H., Fujishima, H., Morii, T., Koshimura, J., Narita, T., Kakei, M., Ito, S. Biochem. Biophys. Res. Commun. (2002) [Pubmed]
  12. Telmisartan prevents obesity and increases the expression of uncoupling protein 1 in diet-induced obese mice. Araki, K., Masaki, T., Katsuragi, I., Tanaka, K., Kakuma, T., Yoshimatsu, H. Hypertension (2006) [Pubmed]
  13. Resistin expression and regulation in mouse pituitary. Morash, B.A., Willkinson, D., Ur, E., Wilkinson, M. FEBS Lett. (2002) [Pubmed]
  14. Dominant inhibitory adipocyte-specific secretory factor (ADSF)/resistin enhances adipogenesis and improves insulin sensitivity. Kim, K.H., Zhao, L., Moon, Y., Kang, C., Sul, H.S. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
  15. Human Resistin Is a Systemic Immune-Derived Proinflammatory Cytokine Targeting both Leukocytes and Adipocytes. Nagaev, I., Bokarewa, M., Tarkowski, A., Smith, U. PLoS ONE (2006) [Pubmed]
  16. Activation of SOCS-3 by resistin. Steppan, C.M., Wang, J., Whiteman, E.L., Birnbaum, M.J., Lazar, M.A. Mol. Cell. Biol. (2005) [Pubmed]
  17. 17 beta-estradiol stimulates resistin gene expression in 3T3-L1 adipocytes via the estrogen receptor, extracellularly regulated kinase, and CCAAT/enhancer binding protein-alpha pathways. Chen, Y.H., Lee, M.J., Chang, H.H., Hung, P.F., Kao, Y.H. Endocrinology (2006) [Pubmed]
  18. Endothelin-1 inhibits resistin secretion in 3T3-L1 adipocytes. Zhong, Q., Lin, C.Y., Clarke, K.J., Kemppainen, R.J., Schwartz, D.D., Judd, R.L. Biochem. Biophys. Res. Commun. (2002) [Pubmed]
  19. Inhibitory effect of green tea (-)-epigallocatechin gallate on resistin gene expression in 3T3-L1 adipocytes depends on the ERK pathway. Liu, H.S., Chen, Y.H., Hung, P.F., Kao, Y.H. Am. J. Physiol. Endocrinol. Metab. (2006) [Pubmed]
  20. Tumor necrosis factor alpha is a negative regulator of resistin gene expression and secretion in 3T3-L1 adipocytes. Fasshauer, M., Klein, J., Neumann, S., Eszlinger, M., Paschke, R. Biochem. Biophys. Res. Commun. (2001) [Pubmed]
  21. Brown adipocytes are novel sites of expression and regulation of adiponectin and resistin. Viengchareun, S., Zennaro, M.C., Pascual-Le Tallec, L., Lombes, M. FEBS Lett. (2002) [Pubmed]
  22. Sexual dimorphism and regulation of resistin, adiponectin, and leptin expression in the mouse. Gui, Y., Silha, J.V., Murphy, L.J. Obes. Res. (2004) [Pubmed]
  23. Adenovirus-mediated high expression of resistin causes dyslipidemia in mice. Sato, N., Kobayashi, K., Inoguchi, T., Sonoda, N., Imamura, M., Sekiguchi, N., Nakashima, N., Nawata, H. Endocrinology (2005) [Pubmed]
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