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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


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Disease relevance of Survivors


High impact information on Survivors


Chemical compound and disease context of Survivors


Biological context of Survivors


Anatomical context of Survivors


Associations of Survivors with chemical compounds


Gene context of Survivors

  • The other two long-term survivors, LTS 9 and LTS 11, had loads of less than 200 copies of RNA/ml of plasma and are infected with viruses with larger deletions in both the nef alone and nef/LTR overlap regions [31].
  • METHODS: Two hundred twenty-two long-term survivors of renal transplantation were examined for polymorphisms in the GSTM1, GSTT1, and GSTP1 genes, using a unified polymerase chain reaction with sequence specific primers (PCR-SSP) genotyping method [32].
  • We have used a peptide 'clamp' to assess the relative roles of continuous GHRH and intermittent SS in GH pulse generation in healthy volunteers and short-and long-term survivors of childhood brain tumours [33].
  • TP53 mutations were found in 12 out of 54 (22%) GBMs of short-term survivors and 8 out of 35 (23%) tumors of long-term survivors; the respective numbers for nuclear p53 protein accumulation were 12/53 (23%) and 10/37 (27%) [34].
  • Waf1/p21 expression was found in 13/53 (25%) tumors of short-term survivors and 9/35 (26%) GBMs of long-term survivors [34].

Analytical, diagnostic and therapeutic context of Survivors


  1. A randomized trial of induction chemotherapy plus high-dose radiation versus radiation alone in stage III non-small-cell lung cancer. Dillman, R.O., Seagren, S.L., Propert, K.J., Guerra, J., Eaton, W.L., Perry, M.C., Carey, R.W., Frei, E.F., Green, M.R. N. Engl. J. Med. (1990) [Pubmed]
  2. Absence of hereditary p53 mutations in 10 familial leukemia pedigrees. Felix, C.A., D'Amico, D., Mitsudomi, T., Nau, M.M., Li, F.P., Fraumeni, J.F., Cole, D.E., McCalla, J., Reaman, G.H., Whang-Peng, J. J. Clin. Invest. (1992) [Pubmed]
  3. Protection against liver damage by cardiotrophin-1: a hepatocyte survival factor up-regulated in the regenerating liver in rats. Bustos, M., Beraza, N., Lasarte, J.J., Baixeras, E., Alzuguren, P., Bordet, T., Prieto, J. Gastroenterology (2003) [Pubmed]
  4. Persistent immunologic abnormalities in long-term survivors of advanced Hodgkin's disease. Fisher, R.I., DeVita, V.T., Bostick, F., Vanhaelen, C., Howser, D.M., Hubbard, S.M., Young, R.C. Ann. Intern. Med. (1980) [Pubmed]
  5. Second marrow transplants in patients with aplastic anemia rejecting the first graft: use of a conditioning regimen including cyclophosphamide and antithymocyte globulin. Storb, R., Weiden, P.L., Sullivan, K.M., Appelbaum, F.R., Beatty, P., Buckner, C.D., Clift, R.A., Doney, K.C., Hansen, J., Martin, P.J. Blood (1987) [Pubmed]
  6. Some aspects of host response to levamisole after chemotherapy in a murine leukemia. Perk, K., Chirigos, M.A., Fuhrman, F., Pettigrew, H. J. Natl. Cancer Inst. (1975) [Pubmed]
  7. Association of 1800 cGy cranial irradiation with intellectual function in children with acute lymphoblastic leukaemia. ISPACC. International Study Group on Psychosocial Aspects of Childhood Cancer. Jankovic, M., Brouwers, P., Valsecchi, M.G., Van Veldhuizen, A., Huisman, J., Kamphuis, R., Kingma, A., Mor, W., Van Dongen-Melman, J., Ferronato, L. Lancet (1994) [Pubmed]
  8. Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukaemia. Lennard, L., Lilleyman, J.S., Van Loon, J., Weinshilboum, R.M. Lancet (1990) [Pubmed]
  9. Ceramide, AIDS and long-term survivors. De Simone, C., Grazia Cifone, M., Roncaioli, P., Moretti, S., Famularo, G., Alesse, E., Boschini, A., Testi, R. Immunol. Today (1996) [Pubmed]
  10. Cardiac hypertrophy in idiopathic dilated congestive cardiomyopathy: a clinicopathologic study. Benjamin, I.J., Schuster, E.H., Bulkley, B.H. Circulation (1981) [Pubmed]
  11. Subclinical late cardiomyopathy after doxorubicin therapy for lymphoma in adults. Hequet, O., Le, Q.H., Moullet, I., Pauli, E., Salles, G., Espinouse, D., Dumontet, C., Thieblemont, C., Arnaud, P., Antal, D., Bouafia, F., Coiffier, B. J. Clin. Oncol. (2004) [Pubmed]
  12. Leukemia following chemotherapy for breast cancer. Curtis, R.E., Boice, J.D., Moloney, W.C., Ries, L.G., Flannery, J.T. Cancer Res. (1990) [Pubmed]
  13. Chronic progressive cardiac dysfunction years after doxorubicin therapy for childhood acute lymphoblastic leukemia. Lipshultz, S.E., Lipsitz, S.R., Sallan, S.E., Dalton, V.M., Mone, S.M., Gelber, R.D., Colan, S.D. J. Clin. Oncol. (2005) [Pubmed]
  14. Intracavitary therapy of murine ovarian cancer with cis-diamminedichloroplatinum(II) and 10-ethyl-10-deazaaminopterin incorporating systemic leucovorin protection. Sirotnak, F.M., Schmid, F.A., DeGraw, J.I. Cancer Res. (1989) [Pubmed]
  15. Myocardial flow reserve in patients with a systemic right ventricle after atrial switch repair. Singh, T.P., Humes, R.A., Muzik, O., Kottamasu, S., Karpawich, P.P., Di Carli, M.F. J. Am. Coll. Cardiol. (2001) [Pubmed]
  16. Longitudinal analysis of human immunodeficiency virus type 1 nef/long terminal repeat sequences in a cohort of long-term survivors infected from a single source. Churchill, M.J., Rhodes, D.I., Learmont, J.C., Sullivan, J.S., Wesselingh, S.L., Cooke, I.R., Deacon, N.J., Gorry, P.R. J. Virol. (2006) [Pubmed]
  17. Late pulmonary haemodynamic changes in heart-lung transplantation. Scott, J.P., Otulana, B.A., Mullins, P.A., Aravoj, D.J., Higenbottam, T., Wallwork, J. Eur. Heart J. (1992) [Pubmed]
  18. Characterization of nef sequences in long-term survivors of human immunodeficiency virus type 1 infection. Huang, Y., Zhang, L., Ho, D.D. J. Virol. (1995) [Pubmed]
  19. p53 codon 72 polymorphism and susceptibility to skin cancer after renal transplantation. Marshall, S.E., Bordea, C., Wojnarowska, F., Morris, P.J., Welsh, K.I. Transplantation (2000) [Pubmed]
  20. Relevance of presenting white blood cell count and kinetics of molecular remission in the prognosis of acute myeloid leukemia with CBFbeta/MYH11 rearrangement. Martín, G., Barragán, E., Bolufer, P., Chillón, C., García-Sanz, R., Gómez, T., Brunet, S., González, M., Sanz, M.A. Haematologica (2000) [Pubmed]
  21. Gastric functions in patients with the intrathoracic stomach after esophageal surgery. Okada, N., Nishimura, O., Sakurai, T., Tsuchihashi, S., Juhri, M. Ann. Surg. (1986) [Pubmed]
  22. Long-lasting bone damage detected by dual-energy x-ray absorptiometry, phalangeal osteosonogrammetry, and in vitro growth of marrow stromal cells after allogeneic stem cell transplantation. Tauchmanovà, L., Serio, B., Del Puente, A., Risitano, A.M., Esposito, A., De Rosa, G., Lombardi, G., Colao, A., Rotoli, B., Selleri, C. J. Clin. Endocrinol. Metab. (2002) [Pubmed]
  23. Long-term persistence of transferred PPD-reactive T cells after allogeneic bone marrow transplantation. Rouleau, M., Senik, A., Leroy, E., Vernant, J.P. Transplantation (1993) [Pubmed]
  24. Beneficial treatment with risedronate in long-term survivors after allogeneic stem cell transplantation for hematological malignancies. Tauchmanovà, L., Selleri, C., Esposito, M., Di Somma, C., Orio, F., Bifulco, G., Palomba, S., Lombardi, G., Rotoli, B., Colao, A. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. (2003) [Pubmed]
  25. Pulmonary function changes in long-term survivors of bone marrow transplantation. Gore, E.M., Lawton, C.A., Ash, R.C., Lipchik, R.J. Int. J. Radiat. Oncol. Biol. Phys. (1996) [Pubmed]
  26. Nodular histiocytic lymphoma: an aggressive nodular lymphoma with potential for prolonged disease-free survival. Osborne, C.K., Norton, L., Young, R.C., Garvin, A.J., Simon, R.M., Berard, C.W., Hubbard, S., DeVita, V.T. Blood (1980) [Pubmed]
  27. Asparaginase-associated lipid abnormalities in children with acute lymphoblastic leukemia. Parsons, S.K., Skapek, S.X., Neufeld, E.J., Kuhlman, C., Young, M.L., Donnelly, M., Brunzell, J.D., Otvos, J.D., Sallan, S.E., Rifai, N. Blood (1997) [Pubmed]
  28. Efficacy of daunorubicin in the therapy of adult acute lymphocytic leukemia: a prospective randomized trial by cancer and leukemia group B. Gottlieb, A.J., Weinberg, V., Ellison, R.R., Henderson, E.S., Terebelo, H., Rafla, S., Cuttner, J., Silver, R.T., Carey, R.W., Levy, R.N. Blood (1984) [Pubmed]
  29. Inhibition of prostaglandin E2 restores defective lymphocyte proliferation and cell-mediated lympholysis in recipients after allogeneic marrow grafting. Klingemann, H.G., Tsoi, M.S., Storb, R. Blood (1986) [Pubmed]
  30. Effects of alpha-difluoromethylornithine alone and combined with adriamycin or vindesine on L1210 leukemia in mice, EMT6 solid tumors in mice, and solid tumors induced by injection of hepatoma tissue culture cells in rats. Bartholeyns, J., Koch-Weser, J. Cancer Res. (1981) [Pubmed]
  31. Characterization of three nef-defective human immunodeficiency virus type 1 strains associated with long-term nonprogression. Australian Long-Term Nonprogressor Study Group. Rhodes, D.I., Ashton, L., Solomon, A., Carr, A., Cooper, D., Kaldor, J., Deacon, N. J. Virol. (2000) [Pubmed]
  32. Glutathione S-transferase polymorphisms and skin cancer after renal transplantation. Marshall, S.E., Bordea, C., Haldar, N.A., Mullighan, C.G., Wojnarowska, F., Morris, P.J., Welsh, K.I. Kidney Int. (2000) [Pubmed]
  33. The relative roles of continuous growth hormone-releasing hormone (GHRH(1-29)NH2) and intermittent somatostatin(1-14)(SS) in growth hormone (GH) pulse generation: studies in normal and post cranial irradiated individuals. Achermann, J.C., Hindmarsh, P.C., Robinson, I.C., Matthews, D.R., Brook, C.G. Clin. Endocrinol. (Oxf) (1999) [Pubmed]
  34. TP53 gene mutations, nuclear p53 accumulation, expression of Waf/p21, Bcl-2, and CD95 (APO-1/Fas) proteins are not prognostic factors in de novo glioblastoma multiforme. Kraus, J.A., Wenghoefer, M., Glesmann, N., Mohr, S., Beck, M., Schmidt, M.C., Schröder, R., Berweiler, U., Roggendorf, W., Diete, S., Dietzmann, K., Heuser, K., Müller, B., Fimmers, R., von Deimling, A., Schlegel, U. J. Neurooncol. (2001) [Pubmed]
  35. Effect of cytokine therapy on survival for patients with advanced renal cell carcinoma. Motzer, R.J., Mazumdar, M., Bacik, J., Russo, P., Berg, W.J., Metz, E.M. J. Clin. Oncol. (2000) [Pubmed]
  36. Corrected QT interval prolongation in anthracycline-treated survivors of childhood cancer. Schwartz, C.L., Hobbie, W.L., Truesdell, S., Constine, L.C., Clark, E.B. J. Clin. Oncol. (1993) [Pubmed]
  37. Alphav integrin expression is a novel marker of poor prognosis in advanced-stage ovarian carcinoma. Goldberg, I., Davidson, B., Reich, R., Gotlieb, W.H., Ben-Baruch, G., Bryne, M., Berner, A., Nesland, J.M., Kopolovic, J. Clin. Cancer Res. (2001) [Pubmed]
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