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MeSH Review

Contact Lenses, Hydrophilic

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Disease relevance of Contact Lenses, Hydrophilic


High impact information on Contact Lenses, Hydrophilic


Chemical compound and disease context of Contact Lenses, Hydrophilic


Biological context of Contact Lenses, Hydrophilic


Anatomical context of Contact Lenses, Hydrophilic

  • Collagen corneal shields allowed a significant (P less than .05) increase in tobramycin penetration into the anterior chamber at 60 minutes compared with hydrophilic soft contact lenses or controls [21].
  • Therefore, ammonia gaseous plasma modification technique was used to modify the surface chemical properties of soft contact lens material such as poly(2-hydroxyethyl methacrylate and methacrylic acid), PHEMA-MAA copolymer, in an attempt to enhance the cell attachment and growth of rabbit corneal epithelial cells [22].
  • The purpose of this study was to compare and evaluate the penetration of amikacin sulfate into aqueous humor of the rabbit eye when applied by different routes and concentrations, namely 100 or 250 mg/ml topical fortified amikacin eye drops, 100 or 250 mg/ml amikacin-embedded soft contact lenses and 25 mg subconjunctival amikacin injection [23].
  • Three soft contact lenses of the HEMA type, discarded because of irritation of the cornea, were processed for and subsequently examined with the SEM, A large portion of the convex surface was covered with globular deposits of fungal spores [24].
  • CONCLUSION: In this patient with partial limbal stem cell deficiency secondary to soft contact lens wear, LASIK was a viable and safe alternative for the correction of myopia [25].

Associations of Contact Lenses, Hydrophilic with chemical compounds

  • The effects of long-term extended wear of soft contact lenses on the human cornea were determined by examining 27 patients who had worn a high water content hydrogel contact lens in 1 eye only for an average of 62 +/- 29 months (mean +/- SD) [26].
  • Therefore, selective adherence by P. aeruginosa to a specific sugar (sialic acid) may be important in the initial attachment of the bacterium to soft contact lenses [27].
  • Six wore daily wear soft contact lenses, two wore extended-wear soft contact lenses, one wore a polymethylmethacrylate hard contact lens, one wore a gas-permeable hard contact lens, and one wore a Saturn lens (combined hard and soft lens) [28].
  • We examined 38 patients who were using soft contact lenses and found that 31 patients had positive ocular provocation test results to a thimerosal-preserved artificial tears solution [29].
  • Two methods are described for the analysis of chlorhexidine sorption in soft contact lenses [30].

Gene context of Contact Lenses, Hydrophilic


Analytical, diagnostic and therapeutic context of Contact Lenses, Hydrophilic


  1. Pseudomonas attachment to low-water and high-water, ionic and nonionic, new and rabbit-worn soft contact lenses. Lawin-Brussel, C.A., Refojo, M.F., Leong, F.L., Kenyon, K.R. Invest. Ophthalmol. Vis. Sci. (1991) [Pubmed]
  2. Delayed hypersensitivity to thimerosal in soft contact lens wearers. Wilson, L.A., McNatt, J., Reitschel, R. Ophthalmology (1981) [Pubmed]
  3. Results of excimer laser photorefractive keratectomy for the correction of myopia. Maguen, E., Salz, J.J., Nesburn, A.B., Warren, C., Macy, J.I., Papaioannou, T., Hofbauer, J., Berlin, M.S. Ophthalmology (1994) [Pubmed]
  4. Circinate-pattern interstitial keratopathy in daily wear soft contact lens wearers. Braude, L.S., Sugar, J. Arch. Ophthalmol. (1985) [Pubmed]
  5. Allergic and toxic reactions of soft contact lens wearers. Mondino, B.J., Salamon, S.M., Zaidman, G.W. Survey of ophthalmology. (1982) [Pubmed]
  6. Fenestrations enhance tear mixing under silicone-hydrogel contact lenses. Miller, K.L., Polse, K.A., Radke, C.J. Invest. Ophthalmol. Vis. Sci. (2003) [Pubmed]
  7. A retrospective study of myopia progression in adult contact lens wearers. Bullimore, M.A., Jones, L.A., Moeschberger, M.L., Zadnik, K., Payor, R.E. Invest. Ophthalmol. Vis. Sci. (2002) [Pubmed]
  8. Analysis of glycoprotein deposits on disposable soft contact lenses. Tripathi, P.C., Tripathi, R.C. Invest. Ophthalmol. Vis. Sci. (1992) [Pubmed]
  9. Isolation and identification of biologically active contaminants from soft contact lenses. I. Nicotine deposits on worn lenses. Broich, J.R., Weiss, L., Rapp, J. Invest. Ophthalmol. Vis. Sci. (1980) [Pubmed]
  10. Observation of soft contact lens disinfection with fluorescent metabolic stains. Gavin, J., Button, N.F., Watson-Craik, I.A., Logan, N.A. Appl. Environ. Microbiol. (2000) [Pubmed]
  11. Adherence of Pseudomonas aeruginosa to hydrophilic contact lenses and other substrata. Miller, M.J., Ahearn, D.G. J. Clin. Microbiol. (1987) [Pubmed]
  12. Association of fungi with extended-wear soft contact lenses. Wilson, L.A., Ahearn, D.G. Am. J. Ophthalmol. (1986) [Pubmed]
  13. Pseudomonas corneal ulcers associated with soft contact-lens wear. Wilson, L.A., Schlitzer, R.L., Ahearn, D.G. Am. J. Ophthalmol. (1981) [Pubmed]
  14. Simplified soft contact lens treatment in corneal diseases. Gasset, A.R., Lobo, L. Annals of ophthalmology. (1977) [Pubmed]
  15. Corneal subepithelial opacities associated with inappropriate contact lens care. Ding, P.C., Lin, C.P. The Kaohsiung journal of medical sciences. (2000) [Pubmed]
  16. Specular microscopic observation of human corneal epithelial abnormalities. Tsubota, K., Yamada, M., Naoi, S. Ophthalmology (1991) [Pubmed]
  17. Chlorhexidine kinetics of hydrophilic contact lenses. Mackeen, D.L., Green, K. J. Pharm. Pharmacol. (1978) [Pubmed]
  18. Corneal light scattering and visual performance in myopic individuals with spectacles, contact lenses, or excimer laser photorefractive keratectomy. Lohmann, C.P., Fitzke, F., O'Brart, D., Muir, M.K., Timberlake, G., Marshall, J. Am. J. Ophthalmol. (1993) [Pubmed]
  19. Detection of complement regulatory proteins on soft contact lenses. Bardenstein, D.S., Sauer, S., Szczotka, L., Medof, M.E. Curr. Eye Res. (1997) [Pubmed]
  20. Do daily wear opaquely tinted hydrogel soft contact lenses affect contrast sensitivity function at one meter? Ozkagnici, A., Zengin, N., Kamiş, O., Gündüz, K. Eye & contact lens. (2003) [Pubmed]
  21. Use of collagen corneal shields versus soft contact lenses to enhance penetration of topical tobramycin. O'Brien, T.P., Sawusch, M.R., Dick, J.D., Hamburg, T.R., Gottsch, J.D. Journal of cataract and refractive surgery. (1988) [Pubmed]
  22. Towards an artificial cornea: surface modifications of optically clear, oxygen permeable soft contact lens materials by ammonia plasma modification technique for the enhanced attachment and growth of corneal epithelial cells. Sipehia, R., Garfinkle, A., Jackson, W.B., Chang, T.M. Biomaterials, artificial cells, and artificial organs. (1990) [Pubmed]
  23. Penetration of amikacin into aqueous humor of rabbits. Erkin, E.F., Günenç U, n.u.l.l., Oner, F.H., Gelal, A., Erkin, Y., Güven, H. Ophthalmologica (2001) [Pubmed]
  24. Fungal growth on soft contact lenses: a SEM-study. Jongebloed, W.L., Humalda, D., Worst, J.F. Documenta ophthalmologica. Advances in ophthalmology. (1987) [Pubmed]
  25. Laser in situ keratomileusis treatment for myopia in a patient with partial limbal stem cell deficiency. Lim, L., Wei, R.H. Eye & contact lens. (2005) [Pubmed]
  26. Effects of long-term extended contact lens wear on the human cornea. Holden, B.A., Sweeney, D.F., Vannas, A., Nilsson, K.T., Efron, N. Invest. Ophthalmol. Vis. Sci. (1985) [Pubmed]
  27. The adherence of Pseudomonas aeruginosa to soft contact lenses. Butrus, S.I., Klotz, S.A., Misra, R.P. Ophthalmology (1987) [Pubmed]
  28. Acanthamoeba keratitis. A growing problem in soft and hard contact lens wearers. Moore, M.B., McCulley, J.P., Newton, C., Cobo, L.M., Foulks, G.N., O'Day, D.M., Johns, K.J., Driebe, W.T., Wilson, L.A., Epstein, R.J. Ophthalmology (1987) [Pubmed]
  29. Ocular inflammation in patients using soft contact lenses. Rietschel, R.L., Wilson, L.A. Archives of dermatology. (1982) [Pubmed]
  30. Analysis of chlorhexidine sorption in soft contact lenses by catalytic oxidation of [14C]chlorhexidine and by liquid chromatography. Stevens, L.E., Durrwachter, J.R., Helton, D.O. Journal of pharmaceutical sciences. (1986) [Pubmed]
  31. Protein adsorption on soft contact lenses. III. Mucin. Castillo, E.J., Koenig, J.L., Anderson, J.M., Jentoft, N. Biomaterials (1986) [Pubmed]
  32. Protein adsorption on hydrogels. II. Reversible and irreversible interactions between lysozyme and soft contact lens surfaces. Castillo, E.J., Koenig, J.L., Anderson, J.M., Lo, J. Biomaterials (1985) [Pubmed]
  33. Fibronectin concentration in tears of contact lens wearers. Baleriola-Lucas, C., Fukuda, M., Willcox, M.D., Sweeney, D.F., Holden, B.A. Exp. Eye Res. (1997) [Pubmed]
  34. Granular corneal dystrophy: treatment with soft contact lenses. Severin, M., Konen, W., Kirchhof, B. Graefes Arch. Clin. Exp. Ophthalmol. (1998) [Pubmed]
  35. A randomized trial of the effects of rigid contact lenses on myopia progression. Walline, J.J., Jones, L.A., Mutti, D.O., Zadnik, K. Arch. Ophthalmol. (2004) [Pubmed]
  36. Mesopic vision in myopia corrected by photorefractive keratectomy, soft contact lenses, and spectacles. Schlote, T., Kriegerowski, M., Bende, T., Derse, M., Thiel, H.J., Jean, B. Journal of cataract and refractive surgery. (1997) [Pubmed]
  37. The nature of backbone monomers determines the performance of imprinted soft contact lenses as timolol drug delivery systems. Hiratani, H., Alvarez-Lorenzo, C. Biomaterials (2004) [Pubmed]
  38. Friction studies of hydrogel contact lenses using AFM: non-crosslinked polymers of low friction at the surface. Kim, S.H., Marmo, C., Somorjai, G.A. Biomaterials (2001) [Pubmed]
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